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The map label for this gene is cyc2 [H]

Identifier: 158317311

GI number: 158317311

Start: 6737020

End: 6739272

Strand: Direct

Name: cyc2 [H]

Synonym: Franean1_5559

Alternate gene names: 158317311

Gene position: 6737020-6739272 (Clockwise)

Preceding gene: 158317310

Following gene: 158317314

Centisome position: 75.01

GC content: 70.08

Gene sequence:

>2253_bases
ATGCAGCCTTTCACGCTCCCGGAGTTCTACCTGCCCTATCCACCCCGGCTGAATCCGAACCTGGAGCACGCCCGCGTGCA
CAGCCGGGCGTGGGCCGGGGAGATGGAGATGATCGACGTACCGCAGGACGGTGTGGCGATCTGGAGCGGGCAGGACTTCG
ACTCCCACGACTACGCGCTGCTGTGCGCGTACACCCATCCGGACGCGGACGAGGCGCGGCTGGATCTCATCACGGACTGG
TACGTCTGGGTTTTCTACTTCGACGACCACTTCCTCGAGGTCTACAAGCGCGGCCGGGATGTCGCCGGAGCCCGCCGGTA
TCTCGACCGGCTGCGCCTGTTCATGCCGGTCGAGGGCGCCGTCACCGCGGAGCCGGCCAACCCGGTCGAGCGTGGCCTCG
CCGACCTGTGGTCCCGCACCGTCCCGGACCGCACGCCGGCCTGGCGGCGGCGGTTCGCGACGAGCACCCGTCATCTGTTG
GACGAGTCCCTGTGGGAGCTGGCCAACATCGACGAGAACCGGCTCGCCAACCCGGTCGAGTACATCGAGATGCGGCGCAA
GGTCGGCGGCGCGCCCTGGTCGGCGAACCTGGTCGAGCACGCGGCGGACGCCGAGGTGCCCGACGCGATCGCCGCGACCC
GGCCGGCGCAGGTGCTGCGGGACACCTTCTCCGACGCCATCCACCTGCGTAACGACCTGTTCTCCTACCAGCGGGAGGTG
CAGGAGGAGGGCGAGCTCAGCAACGGCGTCCTGGTGCTGGAGCGGTTCCTGGACTGCCCGACCCAGCAGGCGGCCGACGC
CGTGAACGACCTGCTGACCTCGCGGCTGCACCAGTTCGAGCACACCGCGCTCACCGAGCTGCCGCCGGTGCTCGACGAGC
ACGGCGTCACCCCGACCGCCCGCCGGGACGTCCTGGCGTACGTCAAGGGGCTGCAGGACTGGCAGGCCGGCGGCCATGAG
TGGCACATGCGGTCCAGCCGCTACATGAACGCGGAGTCCGGGGCGACCGGGCCCGTTCCCGGCAGCCTTCCCGGGGATGC
CACCGGGCTCGGCACGTCGGCGGTGCGTATCGCGGCCTCGCTGCTGGCCACCGCGCCCGCCCGGATGCGCGCTTTCACCC
ACGTCCCGCACCAGGTCGTGGGGCCGGTGAAGCTCCCTGCCTTCTACATGCCGTTCACGACCGGTGAGAGCCGGCATCTG
GCGGCAGCCCGTCACAACATCGTCGAATGGTCGGCGGCGGTCGGGTTTCTCGACCCGGTACCCGGCATCTGGGACGAGCA
CAAGCTCCGGGCGGCCGACTTCGCGCTGTGCTCCGCGGCCATCCATCCGAACGCGACAGCCGCGGAGCTGGACCTGACGA
CGGGATGGCTCACCTGGGGGACCTACGCCGACGACCTCTACCCGGTCCTGTACGGACGGACCCGCGACCTGGCCGGCGCG
CGGGCCTGCACCGAGCGGCTGAAGGAACTCATGCCGGTGGAGCCCGGCCCGCTGCCCGTCCCGGTCGGCGGGCTGGAGCG
CGGCCTCGCCGACCTGTGGCCGCGCACCACCCGGGACATGACGCCCGACTCCCGGCGCACGTTCCGCCGGACGGTCTGCA
TCATGCTCGACAGCTGGCAGTGGGAGCTGGCGAACCAGGCGCAGAACCGTATTCCCGACCCGGTGGACTACATCGAGATG
CGCCGCCGGACCTTCGGCTCGGACCTGACGATGAGCCTGTCCCGGCTCGGGCACGGGCGGTCCGTTCCACCGGAGATCTA
CGGCACCCGGCCGATCAGGGCGCTGGAGAACTCCGCCGCGGATTACTCCTGCCTGCTCAACGATATTTTCTCCTACCAGA
AGGAAATCCAGTTCGAGGGCGAGATCCACAACTGTGTTCTCGTCTTCCAGAACTTTCTCGGCTGCGGCGCCGAACGCGCG
ATCGGCGTGGTCAACGATCTGATGACCGCGCGGCTGCGCGAGTTCGAGCACGTCGTCGACGTCGAGCTGCCCGCCCTCTT
CGACACCTACGAGCTGACGGAGGAGGCGCGGGACGTCCTGCGGGGGTACGTGGGCGAGCTGAAGAGCTGGCTGGCCGGGG
TTCTCCGCTGGCACCAGGGGACGCGGCGTTACGACGAGGCGGAGCTGCGCCACCATCCGGCGGTCGGGGTGCGGCCCTTC
GGGGGGCCGGTCGGTCTCGGCACGTCGGCGGCCGACATCCGGCGGGCGCTATCGGGAAAATCTGGGCAACCGACCGCCCT
GACCGGCTCCTGA

Upstream 100 bases:

>100_bases
CGCTCGGTGTCCTCGAGAACGTCGAGATCGGGCATTAGAAAGCGGCGTCATTCCCTCGGGACACCGGAAATCTCTGGCAG
AGGAAGGTTCTGACCGGCGC

Downstream 100 bases:

>100_bases
AGGCGGACGTCACACCGATCGGCCGCTGAAAGGGCAAGCGACCTGTCCCAGTCCGCCTCGGACGTGTCGGCGACCGTCCC
GGCGATCGCCACGCCGATGT

Product: terpene synthase metal-binding domain-containing protein

Products: NA

Alternate protein names: Sesquiterpene cyclase; Sesquiterpene synthase [H]

Number of amino acids: Translated: 750; Mature: 750

Protein sequence:

>750_residues
MQPFTLPEFYLPYPPRLNPNLEHARVHSRAWAGEMEMIDVPQDGVAIWSGQDFDSHDYALLCAYTHPDADEARLDLITDW
YVWVFYFDDHFLEVYKRGRDVAGARRYLDRLRLFMPVEGAVTAEPANPVERGLADLWSRTVPDRTPAWRRRFATSTRHLL
DESLWELANIDENRLANPVEYIEMRRKVGGAPWSANLVEHAADAEVPDAIAATRPAQVLRDTFSDAIHLRNDLFSYQREV
QEEGELSNGVLVLERFLDCPTQQAADAVNDLLTSRLHQFEHTALTELPPVLDEHGVTPTARRDVLAYVKGLQDWQAGGHE
WHMRSSRYMNAESGATGPVPGSLPGDATGLGTSAVRIAASLLATAPARMRAFTHVPHQVVGPVKLPAFYMPFTTGESRHL
AAARHNIVEWSAAVGFLDPVPGIWDEHKLRAADFALCSAAIHPNATAAELDLTTGWLTWGTYADDLYPVLYGRTRDLAGA
RACTERLKELMPVEPGPLPVPVGGLERGLADLWPRTTRDMTPDSRRTFRRTVCIMLDSWQWELANQAQNRIPDPVDYIEM
RRRTFGSDLTMSLSRLGHGRSVPPEIYGTRPIRALENSAADYSCLLNDIFSYQKEIQFEGEIHNCVLVFQNFLGCGAERA
IGVVNDLMTARLREFEHVVDVELPALFDTYELTEEARDVLRGYVGELKSWLAGVLRWHQGTRRYDEAELRHHPAVGVRPF
GGPVGLGTSAADIRRALSGKSGQPTALTGS

Sequences:

>Translated_750_residues
MQPFTLPEFYLPYPPRLNPNLEHARVHSRAWAGEMEMIDVPQDGVAIWSGQDFDSHDYALLCAYTHPDADEARLDLITDW
YVWVFYFDDHFLEVYKRGRDVAGARRYLDRLRLFMPVEGAVTAEPANPVERGLADLWSRTVPDRTPAWRRRFATSTRHLL
DESLWELANIDENRLANPVEYIEMRRKVGGAPWSANLVEHAADAEVPDAIAATRPAQVLRDTFSDAIHLRNDLFSYQREV
QEEGELSNGVLVLERFLDCPTQQAADAVNDLLTSRLHQFEHTALTELPPVLDEHGVTPTARRDVLAYVKGLQDWQAGGHE
WHMRSSRYMNAESGATGPVPGSLPGDATGLGTSAVRIAASLLATAPARMRAFTHVPHQVVGPVKLPAFYMPFTTGESRHL
AAARHNIVEWSAAVGFLDPVPGIWDEHKLRAADFALCSAAIHPNATAAELDLTTGWLTWGTYADDLYPVLYGRTRDLAGA
RACTERLKELMPVEPGPLPVPVGGLERGLADLWPRTTRDMTPDSRRTFRRTVCIMLDSWQWELANQAQNRIPDPVDYIEM
RRRTFGSDLTMSLSRLGHGRSVPPEIYGTRPIRALENSAADYSCLLNDIFSYQKEIQFEGEIHNCVLVFQNFLGCGAERA
IGVVNDLMTARLREFEHVVDVELPALFDTYELTEEARDVLRGYVGELKSWLAGVLRWHQGTRRYDEAELRHHPAVGVRPF
GGPVGLGTSAADIRRALSGKSGQPTALTGS
>Mature_750_residues
MQPFTLPEFYLPYPPRLNPNLEHARVHSRAWAGEMEMIDVPQDGVAIWSGQDFDSHDYALLCAYTHPDADEARLDLITDW
YVWVFYFDDHFLEVYKRGRDVAGARRYLDRLRLFMPVEGAVTAEPANPVERGLADLWSRTVPDRTPAWRRRFATSTRHLL
DESLWELANIDENRLANPVEYIEMRRKVGGAPWSANLVEHAADAEVPDAIAATRPAQVLRDTFSDAIHLRNDLFSYQREV
QEEGELSNGVLVLERFLDCPTQQAADAVNDLLTSRLHQFEHTALTELPPVLDEHGVTPTARRDVLAYVKGLQDWQAGGHE
WHMRSSRYMNAESGATGPVPGSLPGDATGLGTSAVRIAASLLATAPARMRAFTHVPHQVVGPVKLPAFYMPFTTGESRHL
AAARHNIVEWSAAVGFLDPVPGIWDEHKLRAADFALCSAAIHPNATAAELDLTTGWLTWGTYADDLYPVLYGRTRDLAGA
RACTERLKELMPVEPGPLPVPVGGLERGLADLWPRTTRDMTPDSRRTFRRTVCIMLDSWQWELANQAQNRIPDPVDYIEM
RRRTFGSDLTMSLSRLGHGRSVPPEIYGTRPIRALENSAADYSCLLNDIFSYQKEIQFEGEIHNCVLVFQNFLGCGAERA
IGVVNDLMTARLREFEHVVDVELPALFDTYELTEEARDVLRGYVGELKSWLAGVLRWHQGTRRYDEAELRHHPAVGVRPF
GGPVGLGTSAADIRRALSGKSGQPTALTGS

Specific function: Catalyzes the cyclization of farnesyl diphosphate (FPP) to a 85:15 mixture of the sesquiterpene alcohol germacradienol and the sesquiterpene hydrocarbon germacrene D. Seems also to be able to partially convert the germacradienol formed into geosmin, the c

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the terpene synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005630
- InterPro:   IPR008949 [H]

Pfam domain/function: PF03936 Terpene_synth_C [H]

EC number: =4.2.3.22 [H]

Molecular weight: Translated: 83993; Mature: 83993

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPFTLPEFYLPYPPRLNPNLEHARVHSRAWAGEMEMIDVPQDGVAIWSGQDFDSHDYAL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCCCEE
LCAYTHPDADEARLDLITDWYVWVFYFDDHFLEVYKRGRDVAGARRYLDRLRLFMPVEGA
EEEECCCCCCHHHHHHEEEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
VTAEPANPVERGLADLWSRTVPDRTPAWRRRFATSTRHLLDESLWELANIDENRLANPVE
EECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHH
YIEMRRKVGGAPWSANLVEHAADAEVPDAIAATRPAQVLRDTFSDAIHLRNDLFSYQREV
HHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QEEGELSNGVLVLERFLDCPTQQAADAVNDLLTSRLHQFEHTALTELPPVLDEHGVTPTA
HHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
RRDVLAYVKGLQDWQAGGHEWHMRSSRYMNAESGATGPVPGSLPGDATGLGTSAVRIAAS
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LLATAPARMRAFTHVPHQVVGPVKLPAFYMPFTTGESRHLAAARHNIVEWSAAVGFLDPV
HHHHCHHHHHHHHHCCHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
PGIWDEHKLRAADFALCSAAIHPNATAAELDLTTGWLTWGTYADDLYPVLYGRTRDLAGA
CCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCHHHHHHHHHCCCHHHHHH
RACTERLKELMPVEPGPLPVPVGGLERGLADLWPRTTRDMTPDSRRTFRRTVCIMLDSWQ
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCC
WELANQAQNRIPDPVDYIEMRRRTFGSDLTMSLSRLGHGRSVPPEIYGTRPIRALENSAA
HHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCC
DYSCLLNDIFSYQKEIQFEGEIHNCVLVFQNFLGCGAERAIGVVNDLMTARLREFEHVVD
HHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
VELPALFDTYELTEEARDVLRGYVGELKSWLAGVLRWHQGTRRYDEAELRHHPAVGVRPF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCC
GGPVGLGTSAADIRRALSGKSGQPTALTGS
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQPFTLPEFYLPYPPRLNPNLEHARVHSRAWAGEMEMIDVPQDGVAIWSGQDFDSHDYAL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCCCEE
LCAYTHPDADEARLDLITDWYVWVFYFDDHFLEVYKRGRDVAGARRYLDRLRLFMPVEGA
EEEECCCCCCHHHHHHEEEEEEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
VTAEPANPVERGLADLWSRTVPDRTPAWRRRFATSTRHLLDESLWELANIDENRLANPVE
EECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHH
YIEMRRKVGGAPWSANLVEHAADAEVPDAIAATRPAQVLRDTFSDAIHLRNDLFSYQREV
HHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QEEGELSNGVLVLERFLDCPTQQAADAVNDLLTSRLHQFEHTALTELPPVLDEHGVTPTA
HHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
RRDVLAYVKGLQDWQAGGHEWHMRSSRYMNAESGATGPVPGSLPGDATGLGTSAVRIAAS
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LLATAPARMRAFTHVPHQVVGPVKLPAFYMPFTTGESRHLAAARHNIVEWSAAVGFLDPV
HHHHCHHHHHHHHHCCHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
PGIWDEHKLRAADFALCSAAIHPNATAAELDLTTGWLTWGTYADDLYPVLYGRTRDLAGA
CCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCHHHHHHHHHCCCHHHHHH
RACTERLKELMPVEPGPLPVPVGGLERGLADLWPRTTRDMTPDSRRTFRRTVCIMLDSWQ
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCC
WELANQAQNRIPDPVDYIEMRRRTFGSDLTMSLSRLGHGRSVPPEIYGTRPIRALENSAA
HHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCC
DYSCLLNDIFSYQKEIQFEGEIHNCVLVFQNFLGCGAERAIGVVNDLMTARLREFEHVVD
HHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
VELPALFDTYELTEEARDVLRGYVGELKSWLAGVLRWHQGTRRYDEAELRHHPAVGVRPF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCC
GGPVGLGTSAADIRRALSGKSGQPTALTGS
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]