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The map label for this gene is actII-2 [H]

Identifier: 158317209

GI number: 158317209

Start: 6597582

End: 6599099

Strand: Reverse

Name: actII-2 [H]

Synonym: Franean1_5456

Alternate gene names: 158317209

Gene position: 6599099-6597582 (Counterclockwise)

Preceding gene: 158317211

Following gene: 158317206

Centisome position: 73.47

GC content: 71.94

Gene sequence:

>1518_bases
ATGGTCGAAGCAACACACACCTCTCGGACGCGGGCACCACATCCCGCCGCTGAGCGCCCGGCGGCCGGCGGAGCCCTGCT
GGCCGTCATCCTCCTCGGCCAGTTCATGGCCATCCTGGACGTCAGCATCGTCAACGTGGCGCTGCCGACGTTGCGGACGG
ATCTGGACGTCTCCGGCGCCGGGCTACAGCTGATCGTCGCCGGCTACGTCCTCTCCTACGCGGTTCTGCTGATCACCGGT
GCGCGGCTGGGCGGCATGCTCGGGCACCGGCGCGTGTTCAACACCGGGCTCGCCGGGTTCACCGTGGCCTCGCTGGCCTG
CGGCCTGGCACCCGGCACGTCCTCACTGATCGCCTTTCGGTTCCTGCAGGGGGTCAGCGCCGCGTTGATGACCCCCCAGG
TCATGAGCCTGATCCAGCGCAATTTCGCCGGTGCCGCGCGGATGCGGGCGCTCGGCTACTTCTCCGCGGTGATCGCGGGA
GGCGTCGTCGTCGGCCAGGCCGCCGGCGGGCTGCTCGTCAGCGCGAACCTGTTCGACGCCGGCTGGCGGACCGTCTTCCT
GGTGAACGTGCCGATCGGGGTGCTGCTGCTCGTCGTCGGCCCGCGGGTCATGCCCTCGGACGAGGGGCGCGCGGGGGTCG
ACCTCGACCTTCCCGGCCTGCTCGTTCTCAGCGCGGCGGTGCTGCTCTTCGTGATGCCGCTGATCCTCGGTCACGAGCTG
GGCTGGCCGGCCTGGACGGCCGTGTCGCTGGCGGCGAGTGTCGTCCTGTTCGTGGTCTTCGTCCTGGTGGAGCGGGGCGT
CGCGGCCCGCGGGCGACGTCCGCTGATCTCGGGACGGGTGCTGCGCGCGCCCGGGCTGCTACCCGCCGCCGGCACGCTGC
TGCTCGGGCCGGCGTCGTGGGCCGGGTTCCTGTTCACCACCACCCTGCACCTGCAGGGCGACCTGGGGATGAGTCCGCTG
CGCTCCGGGCTGGCGTTCGTCCCGTGCGTCGTCGCGTTCGCCGCGGTCGGGCTGAGCTGGCAGCGCCTGCCGTCCAGCTG
GCACGCGAACCTGATCCCGGTCGGGCTGGCGTTCGCCGCCGTCTCGTATCTGTTCCTCGGGCCGCTGGCCGGCGGCGGCG
CGCGCTACGAGATCCTCACCGCGTTGATCGGCCTGGGACTCGGCGTGATGTCGATCATCATCTCGGTGACGCTCGAACAC
GTCCCGGTCGAGGACGCGGCCGACGCCAGCGGCCTGCTGCTGACCCTGATGCAGCTCGGCCAGGTCATCGGCATCGCCAC
GGTCGGCACGGTGTTCCTGACCACCGCCGCCGACGGCGGCTCGACCCGCGACGCGGAGTACAGCACCGGCTGGGCGCTCG
CGGCGGTCGCGTTCGTCGCGGCGGCGAGTGCCCTCCTGCTCGCCCGGCGTCGCGGGCGGCAGCTGAGAGTGGTCGTTCCC
GTCCAGGCACACGACGTCGATCCGGACCGTGCGGATCAGGTGATCGTGGCCGCTCCCACAGTGCCGACCGGCGTCTAA

Upstream 100 bases:

>100_bases
CACCAGCTTGTCCTCTGTGCGGCGCCGGTGCCAGGTGCTGCGAGTACCAGTATCGACAGGCTCTCGTTACCAGTATCCGG
ACCGCCCCATGCTGAGGCTC

Downstream 100 bases:

>100_bases
CCCGCGGCCGGGAGGTCGCCCTGCAGGATCGCCAGCCACCCGGCTGTGTGTACGGCCCTGACCTGGTCGCGGGGGGCGTT
GCCGGTGTGGCCGAGGGTGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MVEATHTSRTRAPHPAAERPAAGGALLAVILLGQFMAILDVSIVNVALPTLRTDLDVSGAGLQLIVAGYVLSYAVLLITG
ARLGGMLGHRRVFNTGLAGFTVASLACGLAPGTSSLIAFRFLQGVSAALMTPQVMSLIQRNFAGAARMRALGYFSAVIAG
GVVVGQAAGGLLVSANLFDAGWRTVFLVNVPIGVLLLVVGPRVMPSDEGRAGVDLDLPGLLVLSAAVLLFVMPLILGHEL
GWPAWTAVSLAASVVLFVVFVLVERGVAARGRRPLISGRVLRAPGLLPAAGTLLLGPASWAGFLFTTTLHLQGDLGMSPL
RSGLAFVPCVVAFAAVGLSWQRLPSSWHANLIPVGLAFAAVSYLFLGPLAGGGARYEILTALIGLGLGVMSIIISVTLEH
VPVEDAADASGLLLTLMQLGQVIGIATVGTVFLTTAADGGSTRDAEYSTGWALAAVAFVAAASALLLARRRGRQLRVVVP
VQAHDVDPDRADQVIVAAPTVPTGV

Sequences:

>Translated_505_residues
MVEATHTSRTRAPHPAAERPAAGGALLAVILLGQFMAILDVSIVNVALPTLRTDLDVSGAGLQLIVAGYVLSYAVLLITG
ARLGGMLGHRRVFNTGLAGFTVASLACGLAPGTSSLIAFRFLQGVSAALMTPQVMSLIQRNFAGAARMRALGYFSAVIAG
GVVVGQAAGGLLVSANLFDAGWRTVFLVNVPIGVLLLVVGPRVMPSDEGRAGVDLDLPGLLVLSAAVLLFVMPLILGHEL
GWPAWTAVSLAASVVLFVVFVLVERGVAARGRRPLISGRVLRAPGLLPAAGTLLLGPASWAGFLFTTTLHLQGDLGMSPL
RSGLAFVPCVVAFAAVGLSWQRLPSSWHANLIPVGLAFAAVSYLFLGPLAGGGARYEILTALIGLGLGVMSIIISVTLEH
VPVEDAADASGLLLTLMQLGQVIGIATVGTVFLTTAADGGSTRDAEYSTGWALAAVAFVAAASALLLARRRGRQLRVVVP
VQAHDVDPDRADQVIVAAPTVPTGV
>Mature_505_residues
MVEATHTSRTRAPHPAAERPAAGGALLAVILLGQFMAILDVSIVNVALPTLRTDLDVSGAGLQLIVAGYVLSYAVLLITG
ARLGGMLGHRRVFNTGLAGFTVASLACGLAPGTSSLIAFRFLQGVSAALMTPQVMSLIQRNFAGAARMRALGYFSAVIAG
GVVVGQAAGGLLVSANLFDAGWRTVFLVNVPIGVLLLVVGPRVMPSDEGRAGVDLDLPGLLVLSAAVLLFVMPLILGHEL
GWPAWTAVSLAASVVLFVVFVLVERGVAARGRRPLISGRVLRAPGLLPAAGTLLLGPASWAGFLFTTTLHLQGDLGMSPL
RSGLAFVPCVVAFAAVGLSWQRLPSSWHANLIPVGLAFAAVSYLFLGPLAGGGARYEILTALIGLGLGVMSIIISVTLEH
VPVEDAADASGLLLTLMQLGQVIGIATVGTVFLTTAADGGSTRDAEYSTGWALAAVAFVAAASALLLARRRGRQLRVVVP
VQAHDVDPDRADQVIVAAPTVPTGV

Specific function: Promotes the efflux of actinorhodin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=428, Percent_Identity=29.2056074766355, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790195, Length=244, Percent_Identity=30.327868852459, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788392, Length=479, Percent_Identity=26.9311064718163, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788710, Length=315, Percent_Identity=26.3492063492064, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1789042, Length=180, Percent_Identity=31.1111111111111, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51871; Mature: 51871

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEATHTSRTRAPHPAAERPAAGGALLAVILLGQFMAILDVSIVNVALPTLRTDLDVSGA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GLQLIVAGYVLSYAVLLITGARLGGMLGHRRVFNTGLAGFTVASLACGLAPGTSSLIAFR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHH
FLQGVSAALMTPQVMSLIQRNFAGAARMRALGYFSAVIAGGVVVGQAAGGLLVSANLFDA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECEECC
GWRTVFLVNVPIGVLLLVVGPRVMPSDEGRAGVDLDLPGLLVLSAAVLLFVMPLILGHEL
CCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
GWPAWTAVSLAASVVLFVVFVLVERGVAARGRRPLISGRVLRAPGLLPAAGTLLLGPASW
CCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCEEECCCCCCCCCEEEECCCHH
AGFLFTTTLHLQGDLGMSPLRSGLAFVPCVVAFAAVGLSWQRLPSSWHANLIPVGLAFAA
HHEHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHH
VSYLFLGPLAGGGARYEILTALIGLGLGVMSIIISVTLEHVPVEDAADASGLLLTLMQLG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
QVIGIATVGTVFLTTAADGGSTRDAEYSTGWALAAVAFVAAASALLLARRRGRQLRVVVP
HHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
VQAHDVDPDRADQVIVAAPTVPTGV
EECCCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MVEATHTSRTRAPHPAAERPAAGGALLAVILLGQFMAILDVSIVNVALPTLRTDLDVSGA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GLQLIVAGYVLSYAVLLITGARLGGMLGHRRVFNTGLAGFTVASLACGLAPGTSSLIAFR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHH
FLQGVSAALMTPQVMSLIQRNFAGAARMRALGYFSAVIAGGVVVGQAAGGLLVSANLFDA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECEECC
GWRTVFLVNVPIGVLLLVVGPRVMPSDEGRAGVDLDLPGLLVLSAAVLLFVMPLILGHEL
CCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
GWPAWTAVSLAASVVLFVVFVLVERGVAARGRRPLISGRVLRAPGLLPAAGTLLLGPASW
CCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCEEECCCCCCCCCEEEECCCHH
AGFLFTTTLHLQGDLGMSPLRSGLAFVPCVVAFAAVGLSWQRLPSSWHANLIPVGLAFAA
HHEHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHH
VSYLFLGPLAGGGARYEILTALIGLGLGVMSIIISVTLEHVPVEDAADASGLLLTLMQLG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
QVIGIATVGTVFLTTAADGGSTRDAEYSTGWALAAVAFVAAASALLLARRRGRQLRVVVP
HHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
VQAHDVDPDRADQVIVAAPTVPTGV
EECCCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1878971; 12000953 [H]