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The map label for this gene is ligC [H]

Identifier: 158316925

GI number: 158316925

Start: 6201061

End: 6202287

Strand: Reverse

Name: ligC [H]

Synonym: Franean1_5169

Alternate gene names: 158316925

Gene position: 6202287-6201061 (Counterclockwise)

Preceding gene: 158316926

Following gene: 158316919

Centisome position: 69.05

GC content: 72.94

Gene sequence:

>1227_bases
ATGCGCGAGGATCGGCGGGTGGACCTGCCTGTGACACCGCCGGTGAAGCCGATGCTCGCCCGCGCGGCGCCGCAGATCCC
CCCGGACATGCTGTATGAGCCGAAGTGGGACGGCTTCCGCGCCCTGGTCTTCCGTGACGGGGCCGAGCTGGAGATCACCT
CGCGCAACACCCGGCCGATGACCCGCTACTTCCCCGAGCTGGTCGAGGTGCTGCTCGCGGCACTGCCCGACCGCTGCGTG
CTTGACGGCGAGATCGTCGTCGTCGGCCCGAACGGACTGGACTTCGAGGAGCTGTCGCAACGGGTGCATCCGGCGACCAG
CCGGGTGGCGAAGCTCGCGCTGGAGACCCCGGTCTCGTTCGTCGCGTTCGACCTGCTGGCACTCGGTGACGAGGCGTTCA
CGGACCAGCCGTTCGCCCGGCGGCGCGCCGTGCTCGAGGAGGTTCTCGCCGGCCACGCCGGCCCGGCTGCGCCCGGAACG
GCACCGGCCCGGCGGATCCCGAGCGGGGTCTACCTCACGCCCTCGACCGGCGAGCTCGACATGGCCCGGCAGTGGTTCGA
GCTCTACGAAGGCGCGGGGCTCGACGGGCTGGTCGCCAAGCCGCCGGACGGGGCGTACCAGCCGGACAAGCGCGCAATGT
TCAAGATCAAACATGACCGCACCGCCGACTGCGTCGTGGCCGGCTACCGGCCGCACAAGAACGATCCGGAGGCGGTCGGG
TCGCTGCTGCTCGGGCTCTACGCCGACCCCGCGGACGAGGCCGACCCCGAGAACGCGACGGACCCGGCTCGGGAAAGCCC
GCTGCTGTCCGTCGGGGTCACCTCGGCCTTCCCGATGGCGCGCCGGCGGGAGCTCGTCCGCGAGCTGGCCCATCTCGTGG
TGCCGATCGACTCCCACCCCTGGGCCCGCCAGGGCCCGGAGAACGCCGCGCAGCCGGGCGGCGACGCGGGCGAGGAACCG
GCAGCGGCCGCGGGGCAGCCGGCGCGCACGCCCTGGGACGTCGGGGAGAGCCGGTGGGCCCGTGGCCGTGACCTCTCGTT
CGTCCCGCTGCGGCCCGAGCTGGTCGTCGAGGTGCGCTACGACCACATGGAGGGACCGCGCTTCCGGCACACCACGCAGT
TCGTCCGCTTCCGGCCCGACCGTGACCCCGGCGGATGCACCTACGCCCAGCTCGAGCGTCCGGTGCGGTTCGACATCGCC
GACGTCCTGCGCATCCCGCCGGACTGA

Upstream 100 bases:

>100_bases
TGCCCGACCTGGTCGTGTGCGATCCCGCCCACGCCGAGCAGGTGTTGGCCGTGACCCGCGCGCGCTGACCCGCCTGCCGT
GCTCGCGGTGCGCCGGCCCG

Downstream 100 bases:

>100_bases
CCGGCCCACCAGCAGGCCCAGGCCGAGGCGCGCGGCCGCGGCGGTGCCCGGGCGGCGGGCGCGGTGGGGGGGTCATCCCG
GCGGCACCTTGCCCGCGGGC

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MREDRRVDLPVTPPVKPMLARAAPQIPPDMLYEPKWDGFRALVFRDGAELEITSRNTRPMTRYFPELVEVLLAALPDRCV
LDGEIVVVGPNGLDFEELSQRVHPATSRVAKLALETPVSFVAFDLLALGDEAFTDQPFARRRAVLEEVLAGHAGPAAPGT
APARRIPSGVYLTPSTGELDMARQWFELYEGAGLDGLVAKPPDGAYQPDKRAMFKIKHDRTADCVVAGYRPHKNDPEAVG
SLLLGLYADPADEADPENATDPARESPLLSVGVTSAFPMARRRELVRELAHLVVPIDSHPWARQGPENAAQPGGDAGEEP
AAAAGQPARTPWDVGESRWARGRDLSFVPLRPELVVEVRYDHMEGPRFRHTTQFVRFRPDRDPGGCTYAQLERPVRFDIA
DVLRIPPD

Sequences:

>Translated_408_residues
MREDRRVDLPVTPPVKPMLARAAPQIPPDMLYEPKWDGFRALVFRDGAELEITSRNTRPMTRYFPELVEVLLAALPDRCV
LDGEIVVVGPNGLDFEELSQRVHPATSRVAKLALETPVSFVAFDLLALGDEAFTDQPFARRRAVLEEVLAGHAGPAAPGT
APARRIPSGVYLTPSTGELDMARQWFELYEGAGLDGLVAKPPDGAYQPDKRAMFKIKHDRTADCVVAGYRPHKNDPEAVG
SLLLGLYADPADEADPENATDPARESPLLSVGVTSAFPMARRRELVRELAHLVVPIDSHPWARQGPENAAQPGGDAGEEP
AAAAGQPARTPWDVGESRWARGRDLSFVPLRPELVVEVRYDHMEGPRFRHTTQFVRFRPDRDPGGCTYAQLERPVRFDIA
DVLRIPPD
>Mature_408_residues
MREDRRVDLPVTPPVKPMLARAAPQIPPDMLYEPKWDGFRALVFRDGAELEITSRNTRPMTRYFPELVEVLLAALPDRCV
LDGEIVVVGPNGLDFEELSQRVHPATSRVAKLALETPVSFVAFDLLALGDEAFTDQPFARRRAVLEEVLAGHAGPAAPGT
APARRIPSGVYLTPSTGELDMARQWFELYEGAGLDGLVAKPPDGAYQPDKRAMFKIKHDRTADCVVAGYRPHKNDPEAVG
SLLLGLYADPADEADPENATDPARESPLLSVGVTSAFPMARRRELVRELAHLVVPIDSHPWARQGPENAAQPGGDAGEEP
AAAAGQPARTPWDVGESRWARGRDLSFVPLRPELVVEVRYDHMEGPRFRHTTQFVRFRPDRDPGGCTYAQLERPVRFDIA
DVLRIPPD

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022865
- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 45000; Mature: 45000

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00697 DNA_LIGASE_A1 ; PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREDRRVDLPVTPPVKPMLARAAPQIPPDMLYEPKWDGFRALVFRDGAELEITSRNTRPM
CCCCCEECCCCCCCHHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCEEEECCCCCCH
TRYFPELVEVLLAALPDRCVLDGEIVVVGPNGLDFEELSQRVHPATSRVAKLALETPVSF
HHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHCCHHH
VAFDLLALGDEAFTDQPFARRRAVLEEVLAGHAGPAAPGTAPARRIPSGVYLTPSTGELD
HHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCEEECCCCCCHH
MARQWFELYEGAGLDGLVAKPPDGAYQPDKRAMFKIKHDRTADCVVAGYRPHKNDPEAVG
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCHHHHH
SLLLGLYADPADEADPENATDPARESPLLSVGVTSAFPMARRRELVRELAHLVVPIDSHP
HHHHHHHCCCCCCCCCCCCCCCHHCCCEEEECCHHHCCHHHHHHHHHHHHHHEECCCCCC
WARQGPENAAQPGGDAGEEPAAAAGQPARTPWDVGESRWARGRDLSFVPLRPELVVEVRY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEECCCCEEEEEEEE
DHMEGPRFRHTTQFVRFRPDRDPGGCTYAQLERPVRFDIADVLRIPPD
CCCCCCCHHHHHHHEEECCCCCCCCCCHHHHCCCCEECHHHHHCCCCC
>Mature Secondary Structure
MREDRRVDLPVTPPVKPMLARAAPQIPPDMLYEPKWDGFRALVFRDGAELEITSRNTRPM
CCCCCEECCCCCCCHHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCEEEECCCCCCH
TRYFPELVEVLLAALPDRCVLDGEIVVVGPNGLDFEELSQRVHPATSRVAKLALETPVSF
HHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHCCHHH
VAFDLLALGDEAFTDQPFARRRAVLEEVLAGHAGPAAPGTAPARRIPSGVYLTPSTGELD
HHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCEEECCCCCCHH
MARQWFELYEGAGLDGLVAKPPDGAYQPDKRAMFKIKHDRTADCVVAGYRPHKNDPEAVG
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCHHHHH
SLLLGLYADPADEADPENATDPARESPLLSVGVTSAFPMARRRELVRELAHLVVPIDSHP
HHHHHHHCCCCCCCCCCCCCCCHHCCCEEEECCHHHCCHHHHHHHHHHHHHHEECCCCCC
WARQGPENAAQPGGDAGEEPAAAAGQPARTPWDVGESRWARGRDLSFVPLRPELVVEVRY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEECCCCEEEEEEEE
DHMEGPRFRHTTQFVRFRPDRDPGGCTYAQLERPVRFDIADVLRIPPD
CCCCCCCHHHHHHHEEECCCCCCCCCCHHHHCCCCEECHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA