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The map label for this gene is fusA [C]

Identifier: 158316911

GI number: 158316911

Start: 6176747

End: 6178771

Strand: Direct

Name: fusA [C]

Synonym: Franean1_5155

Alternate gene names: 158316911

Gene position: 6176747-6178771 (Clockwise)

Preceding gene: 158316906

Following gene: 158316913

Centisome position: 68.77

GC content: 75.06

Gene sequence:

>2025_bases
GTGGGTGCCGCCGGGGGCGGCGCGGGCGCATCCCCCGGCGGAGAACCGGCCCAGCGGAGCATCTCGCTCGTCCTGGCTTC
GTTGCGCCACCGTGGCCTGGCCGTGAACCTGCTGGACACCCCCGGATACCCGGACTTCGTCGGGGAGCTGCGAGCGGGCC
TGCGCGCGGCGGACGCCGCCCTGTTCGTCATCAGCGCCCTCGAGGGCATCGACGGGTCGACCAGGATGCTCTGGGAGGAG
TGCGCGGCGGTCGGCATGCCCCGCGCGATCGCCATCACCCGGCTGGACCATCCCCGGGCCGACTTCGACGCGACCCTGCT
CGCCTGCCAGGAGACTTTCGGCGCCGGAGTCCTGCCCGCCTACCTGCCCGAACCCGGCGGCGCGGAGCCGTCCCGGCTCG
TCGCCCTGCTCACCGGACGGGTGATCGAGTACTCGGCCGGGACCCGCCGCGAGCAGGAGCCCCCGGCCGAGCTGACCGGC
GCCGCGGGGGCGGCGCGCGGCGCCCTGGTCGAGGGGATCATCGCCGAGAGCGAGGACGAGAGCCTGCTCGAGCGGTACCT
CGGCGGCGAGGAACTCGACCCCAAGATGCTGCTCGACGACCTGGAGACCGCGGTGGCGCGCGGGTCGTTCTACCCCGTCC
TGCCGCTCGCGGTACCGTCGCGCGCCGCGGCCGGAGCGCGTGGCGTGCCGCCCGGCCTGGGCACCGTGGAGCTGCTCGAC
CTGTTCGCGCACGCCTTCCCGTCCCCGCGCGAGCACCCGCTGCCCAGCCTCACCCGCCCGGACGGCTCACCGTGCCCACC
GGCGGTCGGCGACCCGGCCGGACCCCTGGTCGCCGAGATCGTCCGCACCACCACCGACCCGTACATCGGCCGGATGTCCC
TCGTCCGGGTCTTCTCCGGCATCCTGCGCCCCGACGCGGCCGTACACGTCTCAGGCCACGGACGGGCGGCCGCCGGACAT
CCCGACCACGACGACGACGAGCGGGTCGGGGCGCTCTCGCAGGCCGTCGGCATCGCGCTGCACTCGGTCGACGAATGCGC
CGCCGGCGGGATCTGCGTCATCACCCGGCTGTCCACCGCCGAGACCGGGGACACCCTCTCCGACCCGGCGGACCCGCGCC
ACCTGCCCGCCTGGACGATGCCGGAGCCGCTGCTGCCCGTAGCCGTGCGCGCCCCGGCCCGCTCCGACGAGAGCAAGCTG
TCCGCGGCGCTGGGCCGCGTCTGCGCCGAGGACCCCACCCTGACCGTCACTCAGGACGCCGAGACCGGCCAGCTCGTCCT
GTGGTCCATGGGCGAGGCCCACTGCGACGTCGTCCTGGACCGCCTGCGGGAGCGGTTCGGCGTCACCCTCGAGAAGATCC
CGCTGCGGGTTCCCATGCGGGAGACGCTGCGCGGGCCGGCCGAGGGCGTCGGGCGGCTGGTGAAGCAGTCGGGCGGCCAC
GGGCAGTACGCGATCTGCCGCCTCAAGGTCGAGCCGCTGCCCGCCGGCAGCGGCTTCGAGTTCGTGGACGAGGTCGTCGG
CGGCGCGGTCCCCCGCCAGTTCATTCCCTCGGTGGAGAAGGGAGTGCGGGCCCAGCTGGAGCGGGGGTTGGAGGCCGGGT
TCCCCGCCGTCGACCTGCGGGTGCGCCTGGTCGACGGGAAGGCGCACAGCGTCGACTCGTCCGACATGGCCTTCCAGGCG
GCCGGCGGCCTGGCGCTGCGGGAGGCCGCGCGCGCGGCCGGCGTGGTGCTGCTCGAACCCGTCCTGGAGGTGCACGTCAC
CGTGCCCGACGAGCACGTCGGCGCGGTGATGAGCGACGTCTCCGCGCGGCGCGGCCGGGTCGTGGGGATGGCGCCGGTCG
GCAACGGCGGCCCGGAGGTCCCGGCGCGCACCGCCATCCACGCGGAGATCCCCGCAGCGGAGATGACCCGCTACGCCGTC
GACCTACGCTCCGTGAGCCACGGGACGGGCGTCTTCAGCCGCCGCCCCCTCGGTTACGAGCCGGTTCCCGACCATCTGAC
GGCCAGGTTCACCGAGCAGTCGTGA

Upstream 100 bases:

>100_bases
CGGGAAGGGTGGCAACGGCCGCGCCAACGCCAACGGCAACGGCAGAGGCACCGGCGGCCAGGCCCGCGCCGGGGCCGGGG
CCGACGGGGGCGCGCCCGGG

Downstream 100 bases:

>100_bases
CCCCGCACGGCCGCCCCGCGCCGGCATGACCCGCGCGGGCGCGGCTGTGCCGGACGGCGCAGGGCCCGACCCTCCCGGGT
GACAGCGGGTTACCGCGGAC

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 674; Mature: 673

Protein sequence:

>674_residues
MGAAGGGAGASPGGEPAQRSISLVLASLRHRGLAVNLLDTPGYPDFVGELRAGLRAADAALFVISALEGIDGSTRMLWEE
CAAVGMPRAIAITRLDHPRADFDATLLACQETFGAGVLPAYLPEPGGAEPSRLVALLTGRVIEYSAGTRREQEPPAELTG
AAGAARGALVEGIIAESEDESLLERYLGGEELDPKMLLDDLETAVARGSFYPVLPLAVPSRAAAGARGVPPGLGTVELLD
LFAHAFPSPREHPLPSLTRPDGSPCPPAVGDPAGPLVAEIVRTTTDPYIGRMSLVRVFSGILRPDAAVHVSGHGRAAAGH
PDHDDDERVGALSQAVGIALHSVDECAAGGICVITRLSTAETGDTLSDPADPRHLPAWTMPEPLLPVAVRAPARSDESKL
SAALGRVCAEDPTLTVTQDAETGQLVLWSMGEAHCDVVLDRLRERFGVTLEKIPLRVPMRETLRGPAEGVGRLVKQSGGH
GQYAICRLKVEPLPAGSGFEFVDEVVGGAVPRQFIPSVEKGVRAQLERGLEAGFPAVDLRVRLVDGKAHSVDSSDMAFQA
AGGLALREAARAAGVVLLEPVLEVHVTVPDEHVGAVMSDVSARRGRVVGMAPVGNGGPEVPARTAIHAEIPAAEMTRYAV
DLRSVSHGTGVFSRRPLGYEPVPDHLTARFTEQS

Sequences:

>Translated_674_residues
MGAAGGGAGASPGGEPAQRSISLVLASLRHRGLAVNLLDTPGYPDFVGELRAGLRAADAALFVISALEGIDGSTRMLWEE
CAAVGMPRAIAITRLDHPRADFDATLLACQETFGAGVLPAYLPEPGGAEPSRLVALLTGRVIEYSAGTRREQEPPAELTG
AAGAARGALVEGIIAESEDESLLERYLGGEELDPKMLLDDLETAVARGSFYPVLPLAVPSRAAAGARGVPPGLGTVELLD
LFAHAFPSPREHPLPSLTRPDGSPCPPAVGDPAGPLVAEIVRTTTDPYIGRMSLVRVFSGILRPDAAVHVSGHGRAAAGH
PDHDDDERVGALSQAVGIALHSVDECAAGGICVITRLSTAETGDTLSDPADPRHLPAWTMPEPLLPVAVRAPARSDESKL
SAALGRVCAEDPTLTVTQDAETGQLVLWSMGEAHCDVVLDRLRERFGVTLEKIPLRVPMRETLRGPAEGVGRLVKQSGGH
GQYAICRLKVEPLPAGSGFEFVDEVVGGAVPRQFIPSVEKGVRAQLERGLEAGFPAVDLRVRLVDGKAHSVDSSDMAFQA
AGGLALREAARAAGVVLLEPVLEVHVTVPDEHVGAVMSDVSARRGRVVGMAPVGNGGPEVPARTAIHAEIPAAEMTRYAV
DLRSVSHGTGVFSRRPLGYEPVPDHLTARFTEQS
>Mature_673_residues
GAAGGGAGASPGGEPAQRSISLVLASLRHRGLAVNLLDTPGYPDFVGELRAGLRAADAALFVISALEGIDGSTRMLWEEC
AAVGMPRAIAITRLDHPRADFDATLLACQETFGAGVLPAYLPEPGGAEPSRLVALLTGRVIEYSAGTRREQEPPAELTGA
AGAARGALVEGIIAESEDESLLERYLGGEELDPKMLLDDLETAVARGSFYPVLPLAVPSRAAAGARGVPPGLGTVELLDL
FAHAFPSPREHPLPSLTRPDGSPCPPAVGDPAGPLVAEIVRTTTDPYIGRMSLVRVFSGILRPDAAVHVSGHGRAAAGHP
DHDDDERVGALSQAVGIALHSVDECAAGGICVITRLSTAETGDTLSDPADPRHLPAWTMPEPLLPVAVRAPARSDESKLS
AALGRVCAEDPTLTVTQDAETGQLVLWSMGEAHCDVVLDRLRERFGVTLEKIPLRVPMRETLRGPAEGVGRLVKQSGGHG
QYAICRLKVEPLPAGSGFEFVDEVVGGAVPRQFIPSVEKGVRAQLERGLEAGFPAVDLRVRLVDGKAHSVDSSDMAFQAA
GGLALREAARAAGVVLLEPVLEVHVTVPDEHVGAVMSDVSARRGRVVGMAPVGNGGPEVPARTAIHAEIPAAEMTRYAVD
LRSVSHGTGVFSRRPLGYEPVPDHLTARFTEQS

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=680, Percent_Identity=28.5294117647059, Blast_Score=233, Evalue=7e-61,
Organism=Homo sapiens, GI19923640, Length=677, Percent_Identity=24.0768094534712, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI25306287, Length=289, Percent_Identity=25.2595155709343, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI25306283, Length=351, Percent_Identity=25.0712250712251, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI1789738, Length=649, Percent_Identity=31.7411402157165, Blast_Score=320, Evalue=2e-88,
Organism=Caenorhabditis elegans, GI17533571, Length=663, Percent_Identity=25.3393665158371, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17556745, Length=418, Percent_Identity=22.0095693779904, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323098, Length=645, Percent_Identity=27.4418604651163, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6322359, Length=746, Percent_Identity=23.4584450402145, Blast_Score=141, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24582462, Length=687, Percent_Identity=29.6943231441048, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI221458488, Length=675, Percent_Identity=22.5185185185185, Blast_Score=139, Evalue=7e-33,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 70452; Mature: 70321

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAAGGGAGASPGGEPAQRSISLVLASLRHRGLAVNLLDTPGYPDFVGELRAGLRAADAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
LFVISALEGIDGSTRMLWEECAAVGMPRAIAITRLDHPRADFDATLLACQETFGAGVLPA
HHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHH
YLPEPGGAEPSRLVALLTGRVIEYSAGTRREQEPPAELTGAAGAARGALVEGIIAESEDE
HCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCHH
SLLERYLGGEELDPKMLLDDLETAVARGSFYPVLPLAVPSRAAAGARGVPPGLGTVELLD
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHCCCCCCCCCCCCHHHHHH
LFAHAFPSPREHPLPSLTRPDGSPCPPAVGDPAGPLVAEIVRTTTDPYIGRMSLVRVFSG
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
ILRPDAAVHVSGHGRAAAGHPDHDDDERVGALSQAVGIALHSVDECAAGGICVITRLSTA
HHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
ETGDTLSDPADPRHLPAWTMPEPLLPVAVRAPARSDESKLSAALGRVCAEDPTLTVTQDA
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCC
ETGQLVLWSMGEAHCDVVLDRLRERFGVTLEKIPLRVPMRETLRGPAEGVGRLVKQSGGH
CCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHCCHHHHHHHHHHCCCCC
GQYAICRLKVEPLPAGSGFEFVDEVVGGAVPRQFIPSVEKGVRAQLERGLEAGFPAVDLR
CCEEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VRLVDGKAHSVDSSDMAFQAAGGLALREAARAAGVVLLEPVLEVHVTVPDEHVGAVMSDV
EEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHCCHHEEECCEEEEEECCCHHHHHHHHHH
SARRGRVVGMAPVGNGGPEVPARTAIHAEIPAAEMTRYAVDLRSVSHGTGVFSRRPLGYE
HHHCCCEEEECCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PVPDHLTARFTEQS
CCCCHHHHHCCCCC
>Mature Secondary Structure 
GAAGGGAGASPGGEPAQRSISLVLASLRHRGLAVNLLDTPGYPDFVGELRAGLRAADAA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
LFVISALEGIDGSTRMLWEECAAVGMPRAIAITRLDHPRADFDATLLACQETFGAGVLPA
HHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHH
YLPEPGGAEPSRLVALLTGRVIEYSAGTRREQEPPAELTGAAGAARGALVEGIIAESEDE
HCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCHH
SLLERYLGGEELDPKMLLDDLETAVARGSFYPVLPLAVPSRAAAGARGVPPGLGTVELLD
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHCCCCCCCCCCCCHHHHHH
LFAHAFPSPREHPLPSLTRPDGSPCPPAVGDPAGPLVAEIVRTTTDPYIGRMSLVRVFSG
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
ILRPDAAVHVSGHGRAAAGHPDHDDDERVGALSQAVGIALHSVDECAAGGICVITRLSTA
HHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
ETGDTLSDPADPRHLPAWTMPEPLLPVAVRAPARSDESKLSAALGRVCAEDPTLTVTQDA
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEECCC
ETGQLVLWSMGEAHCDVVLDRLRERFGVTLEKIPLRVPMRETLRGPAEGVGRLVKQSGGH
CCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHCCHHHHHHHHHHCCCCC
GQYAICRLKVEPLPAGSGFEFVDEVVGGAVPRQFIPSVEKGVRAQLERGLEAGFPAVDLR
CCEEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VRLVDGKAHSVDSSDMAFQAAGGLALREAARAAGVVLLEPVLEVHVTVPDEHVGAVMSDV
EEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHCCHHEEECCEEEEEECCCHHHHHHHHHH
SARRGRVVGMAPVGNGGPEVPARTAIHAEIPAAEMTRYAVDLRSVSHGTGVFSRRPLGYE
HHHCCCEEEECCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PVPDHLTARFTEQS
CCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]