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The map label for this gene is engA [H]

Identifier: 158316815

GI number: 158316815

Start: 6055362

End: 6056750

Strand: Reverse

Name: engA [H]

Synonym: Franean1_5057

Alternate gene names: 158316815

Gene position: 6056750-6055362 (Counterclockwise)

Preceding gene: 158316816

Following gene: 158316813

Centisome position: 67.43

GC content: 74.95

Gene sequence:

>1389_bases
ATGAACACCGAAGATCTCGCCGCGTCCGTCGACGACGGCCCTGTGGGCGGTGCCCTCCCGCTGGCGGGAGGGCAGCCCGT
CCTCGCCGTCGTCGGCCGGCCGAACGTGGGCAAGTCGACGCTGGTCAACCGCATCCTGGGCCGCCGCGCGGCCGTCGTCG
AGGACGTCCCCGGCGTCACCCGTGACCGGGTCGCCTACGACGCGGTGTGGAACGGCCGCCGGTTCACCCTCGTCGACACC
GGCGGCTGGGAGCCCGACGCCCGCGGCCTCGCCGCCCGGGTCTCCGACCAGGCCCGCGCCGCGCTCGACACCGCCGACGG
CGTGCTGTTCGTGATCGACGCCACCGTCGGCGCGACCGACGCCGACGAGGCCGTCGCCCGGGTGCTGCACCGGTCGGGCC
GGCCGGTGATCCTCGCCGCGAACAAGGTCGACGACGCCCGCGCGGAGGCCGACGCCGCCGCGCTGTGGAGCCTCGGGCTG
GGCGAGCCGTACCCGGTGTCCGCGCTGCACGGCCGGGGCAGCGGCGACCTGCTGGACGCCGTCCTCGCGGTGCTGCCCGA
GGCACCCCGCGAGCGGTTCACCGAGGAGGACGGCCCCCGGCGCGTGGCGCTGATCGGGCGGCCGAACGTCGGCAAGTCCA
GCCTGCTCAACAAACTGGCCGGCAGCGAGCGCTCGCTGGTGCACGACGTCGCGGGCACGACCCGCGACCCGGTGGACGAG
CTCGTCACCGTCGGCGGCGAGACCTGGATGTTCATCGACACCGCCGGCCTGCGGCGGCGGGTGAAGGAGGCCTCCGGCGC
CGAGTACTACTCGTCGCTGCGCACCGCCTCCGCGCTGGAGGCCGCCGAGGTCGCGATCGTCCTGCTCGCCGCGGACGAGC
CGGTCACCGAGCAGGACCAGCGGATCATCAGCATGGTCACCGACGCCGGCCGGGCCCTCGTCCTCGCCTTCAACAAGTGG
GACACGCTCGACACCGAGCGCCGTCTCGACCTGGAGCAGGAGATCGTCCGCGAGCTGGGCCGGGTGGCCTGGGCGCCGCG
GGTGAACATCTCGGCCCGCACCGGCCGCGCCACCGACCGGCTCGCCCCGGCGCTGCGGACGTCCCTCGACTCGTGGGGAA
CGCGCATCCCGACCGGCCGCCTCAACGCCTGGATCGGAGAGGTCGTGGCGGCCACGCCGCCGCCGTCGCGGGGCGGGAAG
CTGCCGCGGGTGCTGTTCGCGACCCAGGCCGGGGTGCGCCCGCCGCGCTTCGTCGTGTTCACCACCGGATTCCTCGAGCC
GGCCTACCGGCGTTTCCTGGAGCGCAAACTGCGCGAGGACTTCGGCTTCGCCGGCACGCCCATCGAGATCTCGATCCGGG
TCCGCGAGCGTCCCGACCGCCACCGCTAG

Upstream 100 bases:

>100_bases
CGCTGTTTGTTCCGAGTGCGCCGGACGGGTCCGCCGTCCGCGGAAGGACAGCTCGCAGCCAGTTCACCGAGATGTCCAGC
CCAAGCGGAGTGCAGCCGTC

Downstream 100 bases:

>100_bases
ACCCCACCCCGCGGCCTCGGGATGTGTGGTGCCGGACGGCTCCCCTCACGCCCCGGGACTGAGCCGCGCTGTCCTCGCAT
GTCGGCGGGATCGGGCACGG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MNTEDLAASVDDGPVGGALPLAGGQPVLAVVGRPNVGKSTLVNRILGRRAAVVEDVPGVTRDRVAYDAVWNGRRFTLVDT
GGWEPDARGLAARVSDQARAALDTADGVLFVIDATVGATDADEAVARVLHRSGRPVILAANKVDDARAEADAAALWSLGL
GEPYPVSALHGRGSGDLLDAVLAVLPEAPRERFTEEDGPRRVALIGRPNVGKSSLLNKLAGSERSLVHDVAGTTRDPVDE
LVTVGGETWMFIDTAGLRRRVKEASGAEYYSSLRTASALEAAEVAIVLLAADEPVTEQDQRIISMVTDAGRALVLAFNKW
DTLDTERRLDLEQEIVRELGRVAWAPRVNISARTGRATDRLAPALRTSLDSWGTRIPTGRLNAWIGEVVAATPPPSRGGK
LPRVLFATQAGVRPPRFVVFTTGFLEPAYRRFLERKLREDFGFAGTPIEISIRVRERPDRHR

Sequences:

>Translated_462_residues
MNTEDLAASVDDGPVGGALPLAGGQPVLAVVGRPNVGKSTLVNRILGRRAAVVEDVPGVTRDRVAYDAVWNGRRFTLVDT
GGWEPDARGLAARVSDQARAALDTADGVLFVIDATVGATDADEAVARVLHRSGRPVILAANKVDDARAEADAAALWSLGL
GEPYPVSALHGRGSGDLLDAVLAVLPEAPRERFTEEDGPRRVALIGRPNVGKSSLLNKLAGSERSLVHDVAGTTRDPVDE
LVTVGGETWMFIDTAGLRRRVKEASGAEYYSSLRTASALEAAEVAIVLLAADEPVTEQDQRIISMVTDAGRALVLAFNKW
DTLDTERRLDLEQEIVRELGRVAWAPRVNISARTGRATDRLAPALRTSLDSWGTRIPTGRLNAWIGEVVAATPPPSRGGK
LPRVLFATQAGVRPPRFVVFTTGFLEPAYRRFLERKLREDFGFAGTPIEISIRVRERPDRHR
>Mature_462_residues
MNTEDLAASVDDGPVGGALPLAGGQPVLAVVGRPNVGKSTLVNRILGRRAAVVEDVPGVTRDRVAYDAVWNGRRFTLVDT
GGWEPDARGLAARVSDQARAALDTADGVLFVIDATVGATDADEAVARVLHRSGRPVILAANKVDDARAEADAAALWSLGL
GEPYPVSALHGRGSGDLLDAVLAVLPEAPRERFTEEDGPRRVALIGRPNVGKSSLLNKLAGSERSLVHDVAGTTRDPVDE
LVTVGGETWMFIDTAGLRRRVKEASGAEYYSSLRTASALEAAEVAIVLLAADEPVTEQDQRIISMVTDAGRALVLAFNKW
DTLDTERRLDLEQEIVRELGRVAWAPRVNISARTGRATDRLAPALRTSLDSWGTRIPTGRLNAWIGEVVAATPPPSRGGK
LPRVLFATQAGVRPPRFVVFTTGFLEPAYRRFLERKLREDFGFAGTPIEISIRVRERPDRHR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=461, Percent_Identity=36.0086767895879, Blast_Score=274, Evalue=8e-75,
Organism=Escherichia coli, GI1788919, Length=177, Percent_Identity=31.638418079096, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367268, Length=63, Percent_Identity=53.968253968254, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=176, Percent_Identity=25, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45550813, Length=150, Percent_Identity=36, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49750; Mature: 49750

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTEDLAASVDDGPVGGALPLAGGQPVLAVVGRPNVGKSTLVNRILGRRAAVVEDVPGVT
CCCHHHEECCCCCCCCCEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
RDRVAYDAVWNGRRFTLVDTGGWEPDARGLAARVSDQARAALDTADGVLFVIDATVGATD
HHHEEEHEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
ADEAVARVLHRSGRPVILAANKVDDARAEADAAALWSLGLGEPYPVSALHGRGSGDLLDA
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCHHHHHH
VLAVLPEAPRERFTEEDGPRRVALIGRPNVGKSSLLNKLAGSERSLVHDVAGTTRDPVDE
HHHHCCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHH
LVTVGGETWMFIDTAGLRRRVKEASGAEYYSSLRTASALEAAEVAIVLLAADEPVTEQDQ
HHHCCCCEEEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCCHHHH
RIISMVTDAGRALVLAFNKWDTLDTERRLDLEQEIVRELGRVAWAPRVNISARTGRATDR
HHHHHHHCCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCEECCCCCCHHH
LAPALRTSLDSWGTRIPTGRLNAWIGEVVAATPPPSRGGKLPRVLFATQAGVRPPRFVVF
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHCCCCCCEEEEE
TTGFLEPAYRRFLERKLREDFGFAGTPIEISIRVRERPDRHR
ECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MNTEDLAASVDDGPVGGALPLAGGQPVLAVVGRPNVGKSTLVNRILGRRAAVVEDVPGVT
CCCHHHEECCCCCCCCCEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
RDRVAYDAVWNGRRFTLVDTGGWEPDARGLAARVSDQARAALDTADGVLFVIDATVGATD
HHHEEEHEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
ADEAVARVLHRSGRPVILAANKVDDARAEADAAALWSLGLGEPYPVSALHGRGSGDLLDA
HHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCHHHHHH
VLAVLPEAPRERFTEEDGPRRVALIGRPNVGKSSLLNKLAGSERSLVHDVAGTTRDPVDE
HHHHCCCCHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHH
LVTVGGETWMFIDTAGLRRRVKEASGAEYYSSLRTASALEAAEVAIVLLAADEPVTEQDQ
HHHCCCCEEEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCCHHHH
RIISMVTDAGRALVLAFNKWDTLDTERRLDLEQEIVRELGRVAWAPRVNISARTGRATDR
HHHHHHHCCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCEECCCCCCHHH
LAPALRTSLDSWGTRIPTGRLNAWIGEVVAATPPPSRGGKLPRVLFATQAGVRPPRFVVF
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHCCCCCCEEEEE
TTGFLEPAYRRFLERKLREDFGFAGTPIEISIRVRERPDRHR
ECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]