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The map label for this gene is cobQ [H]

Identifier: 158316626

GI number: 158316626

Start: 5835167

End: 5836693

Strand: Reverse

Name: cobQ [H]

Synonym: Franean1_4863

Alternate gene names: 158316626

Gene position: 5836693-5835167 (Counterclockwise)

Preceding gene: 158316627

Following gene: 158316625

Centisome position: 64.98

GC content: 75.25

Gene sequence:

>1527_bases
ATGACGCGCCCGGCCGCGGGCGGGGCACTGCTGGTGGCGGGAACCGCCTCGGACGCGGGTAAGAGCGTCCTGACCGCCGG
CCTGTGCCGCTGGCTGGCCCGCGAAGGGGTGCGTGTCGCGCCGTTCAAGGCCCAGAACATGGCGCTGAACTCGGTGGTCA
CCGCCGACGGCGCCGAGATCGGGCGGGCGCAGGCGATGCAGGCCGCCGCGGCCGGGGTGGAGCCCGAAGCCGCCATGAAC
CCGGTGCTGCTCAAACCGGGATCGGACCGGCACAGCCAGCTTGTCGTGCTCGGCCGTCCCGTCGCCGAGGTCGACGCGCT
CGGGTACCGGCCGCACAAGGAGCGCCTGCTGGGCATCGTCCTGGACTGTCTCGCTGACCTGCGCGGCCGCTTTGACGCGG
TGATCTGCGAGGGCGCCGGGTCACCGGCCGAGATCAACCTGCGCGCGACCGACATCGCCAACATGGGCCTGGCCCGGGCG
GCGAACCTGCCCGTCCTCGTGGTCGGCGACATCGACCGGGGTGGCGTGTTCGCCGCGCTGTTCGGCACGCTCGCCCTGCT
CGACCGGGCCGACCAGACCCACATCGCCGGTTGGGTGATCAACCGGTTCCGGGGCGACGCGCGGCTGCTCGAACCCGGGC
TGCGTCAGCTCGAGGGCCTCACCGGACGTCCCGTCCTCGGCGTGCTGCCGTGGCTGCCCGGCCTGTGGCTGGACGTCGAG
GACTCCCTGGACCTGCGCTCCCACCCCGACCCCGAGGCGGACGGGTCGGGCGCGGCCGACACCGGCCCGGACCGGCTGCG
TGTCGCCGTCGTCCGCTTCCCCCGGCTGTCCAACATCACCGACCTGGACGCCCTGCGCGCCGAGCCGGGGGTCTCCGTGC
GGCTCGCCACCACCCCCGACGAGATCGCCGACGTCGACCTGGTCGTGCTGCCCGGGACCCGTGCCACCGTCTCCGACCTG
GCGTGGCTGCGCCGCCGCGGCCTGGCCGGCGCCCTCGCCGCGCGCGCCACCGCCGGCCTGCCGATCCTCGGCATCTGCGG
CGGATACCAGATGCTCGGGGTGCGCATCGAGGACGAGATCGAGTCGGGTGCCGGCGAGGTGCCGGGGCTCGGCCTGCTGC
CGCTGGTCACCCGCTTCGCCGCCGACAAGGTCCTCGGCCGCCGCCACGGCGTCAGCGCCGACGGGCATCCGGTCACCGGC
TACGAGATCCGCCACGGCCGGCCGGCAGCCGACGACTCCCTGGAGCCGTTCGCGGTGGACGGGGTGCGCCGCGGCGGCGT
GTACGGCACGAGCTGGCACGGCCTGCTGGAGAACGACGAGTTCCGGCGGGCGTTCCTCACCGGGGTGGCGGCGACCGCCG
GCCGTTCGTTCCGCCCCGCCGTCACCTGCTTCGCCGACGTCCGGGCGCGCCGCCTGGACGCCCTCGGCGACCTGGTCGCC
GACCATCTCGACATCGCCACGGTGCGCGCACTGCTCGACCGCGGCGCGCCCGCCGGCCTGCCCTTCGTCCCCCCGGGAGC
ACCCTGA

Upstream 100 bases:

>100_bases
CGGTCAGCGCGGCCTCGGTCGTGGTGTGCGCCGGTGCGGTCGCCGCCCTCGACACGTTGCGGGCGCGCCGGGCGGGCTCC
CGCGGCCCGCGGGAGGCGGG

Downstream 100 bases:

>100_bases
ATGCCGAACACACCGCCGGGCGGCGTCCCGGCCGAGCCGGTGCTGGCCGCTGACCCGGTGCTGGCCCTGGTGTCCACCGC
CGACACCGAGCTGCTCGCCG

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MTRPAAGGALLVAGTASDAGKSVLTAGLCRWLAREGVRVAPFKAQNMALNSVVTADGAEIGRAQAMQAAAAGVEPEAAMN
PVLLKPGSDRHSQLVVLGRPVAEVDALGYRPHKERLLGIVLDCLADLRGRFDAVICEGAGSPAEINLRATDIANMGLARA
ANLPVLVVGDIDRGGVFAALFGTLALLDRADQTHIAGWVINRFRGDARLLEPGLRQLEGLTGRPVLGVLPWLPGLWLDVE
DSLDLRSHPDPEADGSGAADTGPDRLRVAVVRFPRLSNITDLDALRAEPGVSVRLATTPDEIADVDLVVLPGTRATVSDL
AWLRRRGLAGALAARATAGLPILGICGGYQMLGVRIEDEIESGAGEVPGLGLLPLVTRFAADKVLGRRHGVSADGHPVTG
YEIRHGRPAADDSLEPFAVDGVRRGGVYGTSWHGLLENDEFRRAFLTGVAATAGRSFRPAVTCFADVRARRLDALGDLVA
DHLDIATVRALLDRGAPAGLPFVPPGAP

Sequences:

>Translated_508_residues
MTRPAAGGALLVAGTASDAGKSVLTAGLCRWLAREGVRVAPFKAQNMALNSVVTADGAEIGRAQAMQAAAAGVEPEAAMN
PVLLKPGSDRHSQLVVLGRPVAEVDALGYRPHKERLLGIVLDCLADLRGRFDAVICEGAGSPAEINLRATDIANMGLARA
ANLPVLVVGDIDRGGVFAALFGTLALLDRADQTHIAGWVINRFRGDARLLEPGLRQLEGLTGRPVLGVLPWLPGLWLDVE
DSLDLRSHPDPEADGSGAADTGPDRLRVAVVRFPRLSNITDLDALRAEPGVSVRLATTPDEIADVDLVVLPGTRATVSDL
AWLRRRGLAGALAARATAGLPILGICGGYQMLGVRIEDEIESGAGEVPGLGLLPLVTRFAADKVLGRRHGVSADGHPVTG
YEIRHGRPAADDSLEPFAVDGVRRGGVYGTSWHGLLENDEFRRAFLTGVAATAGRSFRPAVTCFADVRARRLDALGDLVA
DHLDIATVRALLDRGAPAGLPFVPPGAP
>Mature_507_residues
TRPAAGGALLVAGTASDAGKSVLTAGLCRWLAREGVRVAPFKAQNMALNSVVTADGAEIGRAQAMQAAAAGVEPEAAMNP
VLLKPGSDRHSQLVVLGRPVAEVDALGYRPHKERLLGIVLDCLADLRGRFDAVICEGAGSPAEINLRATDIANMGLARAA
NLPVLVVGDIDRGGVFAALFGTLALLDRADQTHIAGWVINRFRGDARLLEPGLRQLEGLTGRPVLGVLPWLPGLWLDVED
SLDLRSHPDPEADGSGAADTGPDRLRVAVVRFPRLSNITDLDALRAEPGVSVRLATTPDEIADVDLVVLPGTRATVSDLA
WLRRRGLAGALAARATAGLPILGICGGYQMLGVRIEDEIESGAGEVPGLGLLPLVTRFAADKVLGRRHGVSADGHPVTGY
EIRHGRPAADDSLEPFAVDGVRRGGVYGTSWHGLLENDEFRRAFLTGVAATAGRSFRPAVTCFADVRARRLDALGDLVAD
HLDIATVRALLDRGAPAGLPFVPPGAP

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: 6.3.5.10

Molecular weight: Translated: 53192; Mature: 53060

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPAAGGALLVAGTASDAGKSVLTAGLCRWLAREGVRVAPFKAQNMALNSVVTADGAEI
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCEEEHHEEECCCHHH
GRAQAMQAAAAGVEPEAAMNPVLLKPGSDRHSQLVVLGRPVAEVDALGYRPHKERLLGIV
HHHHHHHHHHCCCCCHHHCCCEEECCCCCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHH
LDCLADLRGRFDAVICEGAGSPAEINLRATDIANMGLARAANLPVLVVGDIDRGGVFAAL
HHHHHHHCCCEEEEEECCCCCCCEEEEEEHHHHHCCHHHHCCCCEEEEECCCCCCHHHHH
FGTLALLDRADQTHIAGWVINRFRGDARLLEPGLRQLEGLTGRPVLGVLPWLPGLWLDVE
HHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECC
DSLDLRSHPDPEADGSGAADTGPDRLRVAVVRFPRLSNITDLDALRAEPGVSVRLATTPD
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHCCCCCEEEEECCCH
EIADVDLVVLPGTRATVSDLAWLRRRGLAGALAARATAGLPILGICGGYQMLGVRIEDEI
HHCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCEEEEEEEEHHHH
ESGAGEVPGLGLLPLVTRFAADKVLGRRHGVSADGHPVTGYEIRHGRPAADDSLEPFAVD
HCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEC
GVRRGGVYGTSWHGLLENDEFRRAFLTGVAATAGRSFRPAVTCFADVRARRLDALGDLVA
CHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DHLDIATVRALLDRGAPAGLPFVPPGAP
HHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRPAAGGALLVAGTASDAGKSVLTAGLCRWLAREGVRVAPFKAQNMALNSVVTADGAEI
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCEEEHHEEECCCHHH
GRAQAMQAAAAGVEPEAAMNPVLLKPGSDRHSQLVVLGRPVAEVDALGYRPHKERLLGIV
HHHHHHHHHHCCCCCHHHCCCEEECCCCCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHH
LDCLADLRGRFDAVICEGAGSPAEINLRATDIANMGLARAANLPVLVVGDIDRGGVFAAL
HHHHHHHCCCEEEEEECCCCCCCEEEEEEHHHHHCCHHHHCCCCEEEEECCCCCCHHHHH
FGTLALLDRADQTHIAGWVINRFRGDARLLEPGLRQLEGLTGRPVLGVLPWLPGLWLDVE
HHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECC
DSLDLRSHPDPEADGSGAADTGPDRLRVAVVRFPRLSNITDLDALRAEPGVSVRLATTPD
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHCCCCCEEEEECCCH
EIADVDLVVLPGTRATVSDLAWLRRRGLAGALAARATAGLPILGICGGYQMLGVRIEDEI
HHCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCEEEEEEEEHHHH
ESGAGEVPGLGLLPLVTRFAADKVLGRRHGVSADGHPVTGYEIRHGRPAADDSLEPFAVD
HCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEC
GVRRGGVYGTSWHGLLENDEFRRAFLTGVAATAGRSFRPAVTCFADVRARRLDALGDLVA
CHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DHLDIATVRALLDRGAPAGLPFVPPGAP
HHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA