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The map label for this gene is orfB [H]

Identifier: 158316600

GI number: 158316600

Start: 5778090

End: 5781521

Strand: Reverse

Name: orfB [H]

Synonym: Franean1_4836

Alternate gene names: 158316600

Gene position: 5781521-5778090 (Counterclockwise)

Preceding gene: 158316601

Following gene: 158316599

Centisome position: 64.37

GC content: 74.97

Gene sequence:

>3432_bases
ATGGCGACGTCCCATGACACGCTCGTCGAGGCACTGCGCGCCTCGCTGCTGGAGAACGAGCGGCTGCAACGGGAGAACGA
CGGACTGCGCAGGGAGAACGTCCAGCTCTCCGAGCCCACCCGTCAGACGCCCGTCCGGGAGCCCGTCGCAATCGTCGGTG
CCGGCTGTCGGCTGCCGGGCGGGGTCACCTCTCCCGACGATCTGTGGCGACTGGTGGACGAGGGCAGGGAGGGCCTCTCG
CCGTTCCCCACCGACCGTGGCTGGGACCTCGAAAAGCTGTTCGACCCCGACCCGACCCGCCCCGGGACGTCCTACGTGCG
GACCGGCGGGTTCCTGGACGCGGCGGCGTTCGACGCCGGGTTCTTCGGCATCGCCCCGCGTGAGGCCCTCGCGATGGACC
CCCAGCAGCGGCTGATGCTCGAAGTGTCCTGGGAGGCGGTCGAACGGGCCGGGATCGACCCGACATCCCTGCGCGGCCGG
CGGGTCGGCGTGTACACGGGCGTGATGTACCACGACTACGCGACCGGCGTGACCGACGTCCCGCCGGAGCTGGAGGGGCT
GCTCGGGACGGGGAACTCCGGCAGCGTGGTCTCCGGGCGGGTCTCCTATCTGCTCGGTCTCGAGGGACCGTCGGTCACCG
TCGACACGGCCTGCTCGTCCTCCCTGGTCGCCGTCCACCTGGCGCTGCGGGCGCTGCGGGCCGGTGAGATCGAGCTTGCC
CTGGTCGGCGGGGTGGCGGTGATGGCCCAGCCGGGTCCGTTCGTCGAGTTCTCCCGCCAGCGGGGGCTCGCGCCCGACGG
CAGGTGCCGGTCGTTCGCGGCGGGCGCCGACGGCACGGGATGGTCCGAGGGCGCCGTGGTGCTGGTCCTCGAGCGACTGG
ACGACGCCCACCGCGACGGACGTCGCGTGCGCGCGCTGGTGCGCGGCTCGGCGGTGAACTCCGACGGGGCGTCCAACGGC
CTGACCGCCCCGAACGGCCCGGCGCAGCAGCGGGTGATCCGCCAGGCGCTCGCCGACGCGGACCTGACCACCCAGGACGT
GGACGTCGTCGAGGGCCACGGGACGGGTACGCCGCTCGGCGACCCGATCGAGGCCCAGGCGCTGCTGGCAACCTACGGAC
GCAGGCCGGCACAGCATCCGCTGTGGCTCGGGTCACTGAAGTCGAACATCGGCCACACCCAGGCGGCGGCCGGGGTGGCC
GGCATCCTCAAGATCGTGGCGGCGCTGGAGCACGCCGAACTGCCCCGGACACTGCACGCCGACGTCCCGTCGGACCAGGT
CGACTGGGAGTCGGGCGCGGTCCGCCTGCTGAGCGAGGCACGGCCGTGGCCCGCGCGTGACCGGCCGCGCCGCGCCGCGG
TCTCGTCCTTCGGCGTGAGCGGCACCAACGCGCACGTCATCCTGGAGCAGGCACCTGAGCCACCGCCCGGCGCCGGTGAA
CCACCGCCCGGCGTGCCCTCGACCGCCGGCGAACTCCCTGACGGGGACGGGAGACCGGCGGGAGCCGGAGCCGCACCGGC
CGCCTGGGTCGTCAGCGCCGCGAGCCGGACGGCGCTGCGGGTCCTCGCCAGGCGGGTGGAAACGGCTCTGCATGAACAGC
CGCACGTGCCGGTCGACGCCGCCGGCGCCGCGTTGCGCACGAGCCGGGCGACGCTGCGCCACCGCGCCGTGGTGATCGCC
GAGGACCGGGAGTCCGGCCTCGCGGGCCTGGCGGCGGCGGCCGCCGGTGAGCCGGCGGCGAACCTGGTGACCGGTTCGGC
GGACGTCGACGGCCAGACCGTCTTCGTCTTCGCCGGCCAGGGCGGCCAGTGGGCGGGGATGGGCGCCGAGCTGCTCGACG
CCTCGCCCGTCTTCGCCGAAGAGGTGGCGCTGGCGGGCCGCGCGCTCGCCCGGCATGTCGGCTGGTCGGTGGAGGACGTG
CTGCGCCAGGTGCCGGGCGCACCCTCGCTCGACCGGGTGGACGTCGTCCAGCCGGCTTCCTTCGCCGTGGCGGCCGGGCT
GGTCCGGCTGTGGGAGTCGGTCGGGGTCCGCCCGGACGCGGTGGTCGGCCACTCGCAGGGCGAGATCGCCGCCGCCTACA
CGGCGGGGGCGCTGAGCCTCGCCGACGCCGCCGCGGTGGTCGCACTGCGCAGCCAGGCGATCGCCGGCGGGCTCACCGGC
CGGGGCGGGATGGCGGCCGTGGCGCTGCCGGTTCCCGCGGTCGCCGAACGGCTCGCGCCGTTCGCTGACCAGGTCGAGCT
CGCCGCCGTGAACGGCCCGGCGTCGGTCGTCCTCGCCGGCGAGCCCGCCGCGCTCGACGAACTGGTGGCCGCCTTCGAGA
GCGAGGGGATCCGGGCCCGCCGGATCCCGGTGGACTACGCCTCGCACAGCCGGCAGGTCGAACGGATCTCCGGTGTCCTC
ATCCAGGCGCTCGCCGGTCTCGACCCGCGCCCGCCGCGGGTGCCGTTCTTCTCGACCGTCGACGCGAAGTGGGTGGAGGA
CGCCGAGCTCGACGGCGGGTACTGGTACCGCAACCTGCGGTGCCCGGTCCGGTTCGCGTCCGCCACGCGGAGCCTGCTCG
ACGGCGGCTACCGGGTGTTCCTCGAGGTGAGCACCCACCCGGTGCTCGCGCCCGCCATCGCGGAGACGGTGGACCAGTGG
GACGGGCCGCCGGTCGCCGTGCTGGAGTCCCTGCGCCGCGACGACGGCGGTCCGGACCGCTTCACCCGCTCCGCCGCGGC
GGCGTTCGTACGCGGGGTCACGGTCGACCTCGCGGGGGCGTCGCACGCCGCCGCCCACGACGGGCTGGCCGGCACCGCCG
ACGGGCCGGCCGGCACCGGCGACCGGCCCGTGCCGTCAGGCGGCGGCGCGGTCGAGCTACCTACGTATCCGTTCCAGCGC
AGGCGCTACTGGCTCGCTTCGACCGGCGCGGGCCGGCCGTCCGGCACGCCTCGTCCGGGTGGCCGCGGCGGTGGGTTGGA
AGTCGACTCCGGAGATGACCACATGACCGGTGACGTGACGCGAGACATCTCGGCCCGGCTACCGGCAGGTTCGGAAGCGG
GCGCGGCGCAGGATGCGGAGCCTGAGCCCGCGGGGTCCGAGAACGCTGGGCCTGGGGACTCAGGGCTTGAGAACGCGGAG
ACGGACGACGCCGGGCAGGAGTTTCGCGCCCGTCTCGCCGAGCTGCCCACCGCCGAGCGGCCTGCCCGGCTCATCGAGCT
GGTCCGGGCGCAGGCCGCCGCGGTGCTAGGTCACGCCGACACCGACGAGGTCGGCCCGGACAGCGCGTTCTTCGACATCG
GGTTCAGCTCGCTGACCGCCGTCGAGCTGCGTAACCGTCTCGCGGCGGCGACCGGCCTCACGCTGCCCGCGATGTTGCTG
TTCGACCACGCGGTGCCCCGCGAGGTCGCCGCGTACCTGCTGGACCGGCTGGAGGTCGAGACCCGTGTTTGA

Upstream 100 bases:

>100_bases
GGCTGGTCGCGCGGGCGCTGGGTCGCACCGCCTGATCCCGCGTTCCCTCCCACCGCCCGGTTCCCGCCCAGCACCCGCCC
CCGAAGCACCGGAGAGTCAC

Downstream 100 bases:

>100_bases
CGTCGAGGCGTACCTGAAGGCGCTCGACCACCGTGGCCCGGCCGACGCGAGCCCTGAGACGCTGCGCCGCCTGCACCACG
CCCACCTGCGGACCGTGCCC

Product: erythronolide synthase

Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1143; Mature: 1142

Protein sequence:

>1143_residues
MATSHDTLVEALRASLLENERLQRENDGLRRENVQLSEPTRQTPVREPVAIVGAGCRLPGGVTSPDDLWRLVDEGREGLS
PFPTDRGWDLEKLFDPDPTRPGTSYVRTGGFLDAAAFDAGFFGIAPREALAMDPQQRLMLEVSWEAVERAGIDPTSLRGR
RVGVYTGVMYHDYATGVTDVPPELEGLLGTGNSGSVVSGRVSYLLGLEGPSVTVDTACSSSLVAVHLALRALRAGEIELA
LVGGVAVMAQPGPFVEFSRQRGLAPDGRCRSFAAGADGTGWSEGAVVLVLERLDDAHRDGRRVRALVRGSAVNSDGASNG
LTAPNGPAQQRVIRQALADADLTTQDVDVVEGHGTGTPLGDPIEAQALLATYGRRPAQHPLWLGSLKSNIGHTQAAAGVA
GILKIVAALEHAELPRTLHADVPSDQVDWESGAVRLLSEARPWPARDRPRRAAVSSFGVSGTNAHVILEQAPEPPPGAGE
PPPGVPSTAGELPDGDGRPAGAGAAPAAWVVSAASRTALRVLARRVETALHEQPHVPVDAAGAALRTSRATLRHRAVVIA
EDRESGLAGLAAAAAGEPAANLVTGSADVDGQTVFVFAGQGGQWAGMGAELLDASPVFAEEVALAGRALARHVGWSVEDV
LRQVPGAPSLDRVDVVQPASFAVAAGLVRLWESVGVRPDAVVGHSQGEIAAAYTAGALSLADAAAVVALRSQAIAGGLTG
RGGMAAVALPVPAVAERLAPFADQVELAAVNGPASVVLAGEPAALDELVAAFESEGIRARRIPVDYASHSRQVERISGVL
IQALAGLDPRPPRVPFFSTVDAKWVEDAELDGGYWYRNLRCPVRFASATRSLLDGGYRVFLEVSTHPVLAPAIAETVDQW
DGPPVAVLESLRRDDGGPDRFTRSAAAAFVRGVTVDLAGASHAAAHDGLAGTADGPAGTGDRPVPSGGGAVELPTYPFQR
RRYWLASTGAGRPSGTPRPGGRGGGLEVDSGDDHMTGDVTRDISARLPAGSEAGAAQDAEPEPAGSENAGPGDSGLENAE
TDDAGQEFRARLAELPTAERPARLIELVRAQAAAVLGHADTDEVGPDSAFFDIGFSSLTAVELRNRLAAATGLTLPAMLL
FDHAVPREVAAYLLDRLEVETRV

Sequences:

>Translated_1143_residues
MATSHDTLVEALRASLLENERLQRENDGLRRENVQLSEPTRQTPVREPVAIVGAGCRLPGGVTSPDDLWRLVDEGREGLS
PFPTDRGWDLEKLFDPDPTRPGTSYVRTGGFLDAAAFDAGFFGIAPREALAMDPQQRLMLEVSWEAVERAGIDPTSLRGR
RVGVYTGVMYHDYATGVTDVPPELEGLLGTGNSGSVVSGRVSYLLGLEGPSVTVDTACSSSLVAVHLALRALRAGEIELA
LVGGVAVMAQPGPFVEFSRQRGLAPDGRCRSFAAGADGTGWSEGAVVLVLERLDDAHRDGRRVRALVRGSAVNSDGASNG
LTAPNGPAQQRVIRQALADADLTTQDVDVVEGHGTGTPLGDPIEAQALLATYGRRPAQHPLWLGSLKSNIGHTQAAAGVA
GILKIVAALEHAELPRTLHADVPSDQVDWESGAVRLLSEARPWPARDRPRRAAVSSFGVSGTNAHVILEQAPEPPPGAGE
PPPGVPSTAGELPDGDGRPAGAGAAPAAWVVSAASRTALRVLARRVETALHEQPHVPVDAAGAALRTSRATLRHRAVVIA
EDRESGLAGLAAAAAGEPAANLVTGSADVDGQTVFVFAGQGGQWAGMGAELLDASPVFAEEVALAGRALARHVGWSVEDV
LRQVPGAPSLDRVDVVQPASFAVAAGLVRLWESVGVRPDAVVGHSQGEIAAAYTAGALSLADAAAVVALRSQAIAGGLTG
RGGMAAVALPVPAVAERLAPFADQVELAAVNGPASVVLAGEPAALDELVAAFESEGIRARRIPVDYASHSRQVERISGVL
IQALAGLDPRPPRVPFFSTVDAKWVEDAELDGGYWYRNLRCPVRFASATRSLLDGGYRVFLEVSTHPVLAPAIAETVDQW
DGPPVAVLESLRRDDGGPDRFTRSAAAAFVRGVTVDLAGASHAAAHDGLAGTADGPAGTGDRPVPSGGGAVELPTYPFQR
RRYWLASTGAGRPSGTPRPGGRGGGLEVDSGDDHMTGDVTRDISARLPAGSEAGAAQDAEPEPAGSENAGPGDSGLENAE
TDDAGQEFRARLAELPTAERPARLIELVRAQAAAVLGHADTDEVGPDSAFFDIGFSSLTAVELRNRLAAATGLTLPAMLL
FDHAVPREVAAYLLDRLEVETRV
>Mature_1142_residues
ATSHDTLVEALRASLLENERLQRENDGLRRENVQLSEPTRQTPVREPVAIVGAGCRLPGGVTSPDDLWRLVDEGREGLSP
FPTDRGWDLEKLFDPDPTRPGTSYVRTGGFLDAAAFDAGFFGIAPREALAMDPQQRLMLEVSWEAVERAGIDPTSLRGRR
VGVYTGVMYHDYATGVTDVPPELEGLLGTGNSGSVVSGRVSYLLGLEGPSVTVDTACSSSLVAVHLALRALRAGEIELAL
VGGVAVMAQPGPFVEFSRQRGLAPDGRCRSFAAGADGTGWSEGAVVLVLERLDDAHRDGRRVRALVRGSAVNSDGASNGL
TAPNGPAQQRVIRQALADADLTTQDVDVVEGHGTGTPLGDPIEAQALLATYGRRPAQHPLWLGSLKSNIGHTQAAAGVAG
ILKIVAALEHAELPRTLHADVPSDQVDWESGAVRLLSEARPWPARDRPRRAAVSSFGVSGTNAHVILEQAPEPPPGAGEP
PPGVPSTAGELPDGDGRPAGAGAAPAAWVVSAASRTALRVLARRVETALHEQPHVPVDAAGAALRTSRATLRHRAVVIAE
DRESGLAGLAAAAAGEPAANLVTGSADVDGQTVFVFAGQGGQWAGMGAELLDASPVFAEEVALAGRALARHVGWSVEDVL
RQVPGAPSLDRVDVVQPASFAVAAGLVRLWESVGVRPDAVVGHSQGEIAAAYTAGALSLADAAAVVALRSQAIAGGLTGR
GGMAAVALPVPAVAERLAPFADQVELAAVNGPASVVLAGEPAALDELVAAFESEGIRARRIPVDYASHSRQVERISGVLI
QALAGLDPRPPRVPFFSTVDAKWVEDAELDGGYWYRNLRCPVRFASATRSLLDGGYRVFLEVSTHPVLAPAIAETVDQWD
GPPVAVLESLRRDDGGPDRFTRSAAAAFVRGVTVDLAGASHAAAHDGLAGTADGPAGTGDRPVPSGGGAVELPTYPFQRR
RYWLASTGAGRPSGTPRPGGRGGGLEVDSGDDHMTGDVTRDISARLPAGSEAGAAQDAEPEPAGSENAGPGDSGLENAET
DDAGQEFRARLAELPTAERPARLIELVRAQAAAVLGHADTDEVGPDSAFFDIGFSSLTAVELRNRLAAATGLTLPAMLLF
DHAVPREVAAYLLDRLEVETRV

Specific function: May be involved in the biosynthesis of the oleandomycin lactone ring [H]

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=367, Percent_Identity=37.3297002724796, Blast_Score=236, Evalue=6e-62,
Organism=Homo sapiens, GI8923559, Length=278, Percent_Identity=29.8561151079137, Blast_Score=107, Evalue=9e-23,
Organism=Homo sapiens, GI310129082, Length=86, Percent_Identity=39.5348837209302, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI310109937, Length=86, Percent_Identity=39.5348837209302, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI239744023, Length=86, Percent_Identity=39.5348837209302, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1787337, Length=283, Percent_Identity=28.9752650176678, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1787334, Length=293, Percent_Identity=29.3515358361775, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1788663, Length=272, Percent_Identity=25.3676470588235, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI212642053, Length=756, Percent_Identity=29.2328042328042, Blast_Score=291, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17550940, Length=452, Percent_Identity=35.3982300884956, Blast_Score=234, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI71983541, Length=278, Percent_Identity=29.4964028776978, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71983535, Length=269, Percent_Identity=29.7397769516729, Blast_Score=102, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6320904, Length=452, Percent_Identity=23.4513274336283, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24581345, Length=755, Percent_Identity=29.2715231788079, Blast_Score=287, Evalue=4e-77,
Organism=Drosophila melanogaster, GI221330659, Length=884, Percent_Identity=28.2805429864253, Blast_Score=283, Evalue=4e-76,
Organism=Drosophila melanogaster, GI19920632, Length=884, Percent_Identity=28.2805429864253, Blast_Score=283, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24644341, Length=459, Percent_Identity=27.0152505446623, Blast_Score=116, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR000794
- InterPro:   IPR002198
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR013968
- InterPro:   IPR020806
- InterPro:   IPR020802
- InterPro:   IPR015083
- InterPro:   IPR006162
- InterPro:   IPR001031
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF00106 adh_short; PF08990 Docking; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 118769; Mature: 118638

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSHDTLVEALRASLLENERLQRENDGLRRENVQLSEPTRQTPVREPVAIVGAGCRLPG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
GVTSPDDLWRLVDEGREGLSPFPTDRGWDLEKLFDPDPTRPGTSYVRTGGFLDAAAFDAG
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHCCCCHHHHHHCCC
FFGIAPREALAMDPQQRLMLEVSWEAVERAGIDPTSLRGRRVGVYTGVMYHDYATGVTDV
CCCCCCHHHHHCCHHHHEEEEECHHHHHHCCCCHHHCCCCEEEEEECEEEEHHCCCCCCC
PPELEGLLGTGNSGSVVSGRVSYLLGLEGPSVTVDTACSSSLVAVHLALRALRAGEIELA
CHHHHHHEECCCCCCEEECEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEEE
LVGGVAVMAQPGPFVEFSRQRGLAPDGRCRSFAAGADGTGWSEGAVVLVLERLDDAHRDG
EECCEEEEECCCCCHHHHHHCCCCCCCCCCCEECCCCCCCCCCCEEEEEEHHHHHHHHHH
RRVRALVRGSAVNSDGASNGLTAPNGPAQQRVIRQALADADLTTQDVDVVEGHGTGTPLG
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
DPIEAQALLATYGRRPAQHPLWLGSLKSNIGHTQAAAGVAGILKIVAALEHAELPRTLHA
CCHHHHHHHHHHCCCCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
DVPSDQVDWESGAVRLLSEARPWPARDRPRRAAVSSFGVSGTNAHVILEQAPEPPPGAGE
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
PPPGVPSTAGELPDGDGRPAGAGAAPAAWVVSAASRTALRVLARRVETALHEQPHVPVDA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AGAALRTSRATLRHRAVVIAEDRESGLAGLAAAAAGEPAANLVTGSADVDGQTVFVFAGQ
CCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCCCHHEEECCCCCCCCEEEEEECC
GGQWAGMGAELLDASPVFAEEVALAGRALARHVGWSVEDVLRQVPGAPSLDRVDVVQPAS
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHH
FAVAAGLVRLWESVGVRPDAVVGHSQGEIAAAYTAGALSLADAAAVVALRSQAIAGGLTG
HHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RGGMAAVALPVPAVAERLAPFADQVELAAVNGPASVVLAGEPAALDELVAAFESEGIRAR
CCCCEEEECCCHHHHHHHCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCEEE
RIPVDYASHSRQVERISGVLIQALAGLDPRPPRVPFFSTVDAKWVEDAELDGGYWYRNLR
ECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEEECC
CPVRFASATRSLLDGGYRVFLEVSTHPVLAPAIAETVDQWDGPPVAVLESLRRDDGGPDR
CCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHH
FTRSAAAAFVRGVTVDLAGASHAAAHDGLAGTADGPAGTGDRPVPSGGGAVELPTYPFQR
HHHHHHHHHHHCCEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHH
RRYWLASTGAGRPSGTPRPGGRGGGLEVDSGDDHMTGDVTRDISARLPAGSEAGAAQDAE
CEEEEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCC
PEPAGSENAGPGDSGLENAETDDAGQEFRARLAELPTAERPARLIELVRAQAAAVLGHAD
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
TDEVGPDSAFFDIGFSSLTAVELRNRLAAATGLTLPAMLLFDHAVPREVAAYLLDRLEVE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
TRV
CCC
>Mature Secondary Structure 
ATSHDTLVEALRASLLENERLQRENDGLRRENVQLSEPTRQTPVREPVAIVGAGCRLPG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
GVTSPDDLWRLVDEGREGLSPFPTDRGWDLEKLFDPDPTRPGTSYVRTGGFLDAAAFDAG
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHCCCCHHHHHHCCC
FFGIAPREALAMDPQQRLMLEVSWEAVERAGIDPTSLRGRRVGVYTGVMYHDYATGVTDV
CCCCCCHHHHHCCHHHHEEEEECHHHHHHCCCCHHHCCCCEEEEEECEEEEHHCCCCCCC
PPELEGLLGTGNSGSVVSGRVSYLLGLEGPSVTVDTACSSSLVAVHLALRALRAGEIELA
CHHHHHHEECCCCCCEEECEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEEE
LVGGVAVMAQPGPFVEFSRQRGLAPDGRCRSFAAGADGTGWSEGAVVLVLERLDDAHRDG
EECCEEEEECCCCCHHHHHHCCCCCCCCCCCEECCCCCCCCCCCEEEEEEHHHHHHHHHH
RRVRALVRGSAVNSDGASNGLTAPNGPAQQRVIRQALADADLTTQDVDVVEGHGTGTPLG
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
DPIEAQALLATYGRRPAQHPLWLGSLKSNIGHTQAAAGVAGILKIVAALEHAELPRTLHA
CCHHHHHHHHHHCCCCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEC
DVPSDQVDWESGAVRLLSEARPWPARDRPRRAAVSSFGVSGTNAHVILEQAPEPPPGAGE
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
PPPGVPSTAGELPDGDGRPAGAGAAPAAWVVSAASRTALRVLARRVETALHEQPHVPVDA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AGAALRTSRATLRHRAVVIAEDRESGLAGLAAAAAGEPAANLVTGSADVDGQTVFVFAGQ
CCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHCCCCCHHEEECCCCCCCCEEEEEECC
GGQWAGMGAELLDASPVFAEEVALAGRALARHVGWSVEDVLRQVPGAPSLDRVDVVQPAS
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHH
FAVAAGLVRLWESVGVRPDAVVGHSQGEIAAAYTAGALSLADAAAVVALRSQAIAGGLTG
HHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RGGMAAVALPVPAVAERLAPFADQVELAAVNGPASVVLAGEPAALDELVAAFESEGIRAR
CCCCEEEECCCHHHHHHHCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCEEE
RIPVDYASHSRQVERISGVLIQALAGLDPRPPRVPFFSTVDAKWVEDAELDGGYWYRNLR
ECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEEECC
CPVRFASATRSLLDGGYRVFLEVSTHPVLAPAIAETVDQWDGPPVAVLESLRRDDGGPDR
CCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHH
FTRSAAAAFVRGVTVDLAGASHAAAHDGLAGTADGPAGTGDRPVPSGGGAVELPTYPFQR
HHHHHHHHHHHCCEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHH
RRYWLASTGAGRPSGTPRPGGRGGGLEVDSGDDHMTGDVTRDISARLPAGSEAGAAQDAE
CEEEEEECCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCC
PEPAGSENAGPGDSGLENAETDDAGQEFRARLAELPTAERPARLIELVRAQAAAVLGHAD
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
TDEVGPDSAFFDIGFSSLTAVELRNRLAAATGLTLPAMLLFDHAVPREVAAYLLDRLEVE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
TRV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: None [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} [C]

Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]

Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8107683 [H]