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The map label for this gene is ubiE [H]

Identifier: 158316596

GI number: 158316596

Start: 5771179

End: 5772042

Strand: Reverse

Name: ubiE [H]

Synonym: Franean1_4832

Alternate gene names: 158316596

Gene position: 5772042-5771179 (Counterclockwise)

Preceding gene: 158316597

Following gene: 158316595

Centisome position: 64.26

GC content: 69.68

Gene sequence:

>864_bases
ATGGCGCATCCCACGAGCGCGCTCGCGGCAGAGGTCGGGAAGTTCTACGACCACCTCACGACCTACCAGACCGCGCAGGA
CGAGGATCTCAACTTCCACTTCGGCTACTGGGACGTGCCGCCCGACGGCACCCCGCCCGCCCCCGGCACGGACGTCGCCG
AACTCGAGGCGGCGGCCGAGCGCCTCACCGAGTTGATGATCGAGAAGATCCGGGTCCGGACCGGGGACCGGGTGCTCGAC
GTGGGATCGGGCTCCGGCATCCCCGCCGTCCGCCTGACCCGGGCTACCGGAGCTTCGGTCGTCGGGATCTCGATCAGCCG
GGAGCAGGTGCGGCGCTCGACCGACCGGGCGCGCGACGAGAACCTCTCCGACCGGCTGGAGTTCGAGTACGCCGACGCCG
CGGAGCTTCCCTTCGGTCCGGATTCCTTCGACGCCGCCTGGGCGCTGGAATCCATCATTCACGTCCCCGACCGCGCCCAG
GTGCTGCGGGAGATCGCCCGGGTCATCCGGCCGGGCGGCCGTTTCGTCGCCACCGACATCTTCGAGCGGTCGCCGGTCCC
GGACGAGAAGCGGCACGCGGTCGACAGCTTCTATTCCGGTCTGCTGCTCGGTCCGAGTGTTCGGTTCGACGACTATCCGG
CGCTGCTGCGCGGGGCGGGGCTGCGCCCGCTGGAACTCATCGATGTCAGCGACCAGGTGATCGCGCGGTCGTTCCAGCTG
CTCGCCGAGCGGATCCGCCGGGACAAGGAGAACCTCGACGACCTGCTCGGCGACGAGCTGTACCAGCGTCTCGCCAGCAC
GGGTGTGGACGGGCTCCGTGAGATCGGCTACCTCGTCGTGGTGGCCGAGCGTCCGACCGAGTAA

Upstream 100 bases:

>100_bases
GCCGGCCCGGCCGGCCCGGCCGACCTGGCTGACCCGGCAGACCCGGCGCGCGGGACGTCCCGCGCGCCGCACCCATCAGA
CACCTCATGGAGGGATCTTC

Downstream 100 bases:

>100_bases
CGACCCGCCCGGCGAAAGAGGGGGTTCTTAGGGGAGTTTTCCGGCCGTCGGCCGGTGCCACCATTCTGCAATGTCCCCTT
TTTCTCGTCCGCGGCTTTCC

Product: type 11 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MAHPTSALAAEVGKFYDHLTTYQTAQDEDLNFHFGYWDVPPDGTPPAPGTDVAELEAAAERLTELMIEKIRVRTGDRVLD
VGSGSGIPAVRLTRATGASVVGISISREQVRRSTDRARDENLSDRLEFEYADAAELPFGPDSFDAAWALESIIHVPDRAQ
VLREIARVIRPGGRFVATDIFERSPVPDEKRHAVDSFYSGLLLGPSVRFDDYPALLRGAGLRPLELIDVSDQVIARSFQL
LAERIRRDKENLDDLLGDELYQRLASTGVDGLREIGYLVVVAERPTE

Sequences:

>Translated_287_residues
MAHPTSALAAEVGKFYDHLTTYQTAQDEDLNFHFGYWDVPPDGTPPAPGTDVAELEAAAERLTELMIEKIRVRTGDRVLD
VGSGSGIPAVRLTRATGASVVGISISREQVRRSTDRARDENLSDRLEFEYADAAELPFGPDSFDAAWALESIIHVPDRAQ
VLREIARVIRPGGRFVATDIFERSPVPDEKRHAVDSFYSGLLLGPSVRFDDYPALLRGAGLRPLELIDVSDQVIARSFQL
LAERIRRDKENLDDLLGDELYQRLASTGVDGLREIGYLVVVAERPTE
>Mature_286_residues
AHPTSALAAEVGKFYDHLTTYQTAQDEDLNFHFGYWDVPPDGTPPAPGTDVAELEAAAERLTELMIEKIRVRTGDRVLDV
GSGSGIPAVRLTRATGASVVGISISREQVRRSTDRARDENLSDRLEFEYADAAELPFGPDSFDAAWALESIIHVPDRAQV
LREIARVIRPGGRFVATDIFERSPVPDEKRHAVDSFYSGLLLGPSVRFDDYPALLRGAGLRPLELIDVSDQVIARSFQLL
AERIRRDKENLDDLLGDELYQRLASTGVDGLREIGYLVVVAERPTE

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=235, Percent_Identity=22.5531914893617, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25143945, Length=164, Percent_Identity=31.0975609756098, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323635, Length=144, Percent_Identity=32.6388888888889, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31758; Mature: 31627

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHPTSALAAEVGKFYDHLTTYQTAQDEDLNFHFGYWDVPPDGTPPAPGTDVAELEAAAE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECEEECCCCCCCCCCCCCHHHHHHHHH
RLTELMIEKIRVRTGDRVLDVGSGSGIPAVRLTRATGASVVGISISREQVRRSTDRARDE
HHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHC
NLSDRLEFEYADAAELPFGPDSFDAAWALESIIHVPDRAQVLREIARVIRPGGRFVATDI
CCHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEHHH
FERSPVPDEKRHAVDSFYSGLLLGPSVRFDDYPALLRGAGLRPLELIDVSDQVIARSFQL
HHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEECCHHHHHHHHHHH
LAERIRRDKENLDDLLGDELYQRLASTGVDGLREIGYLVVVAERPTE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEECCCCC
>Mature Secondary Structure 
AHPTSALAAEVGKFYDHLTTYQTAQDEDLNFHFGYWDVPPDGTPPAPGTDVAELEAAAE
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECEEECCCCCCCCCCCCCHHHHHHHHH
RLTELMIEKIRVRTGDRVLDVGSGSGIPAVRLTRATGASVVGISISREQVRRSTDRARDE
HHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHC
NLSDRLEFEYADAAELPFGPDSFDAAWALESIIHVPDRAQVLREIARVIRPGGRFVATDI
CCHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEHHH
FERSPVPDEKRHAVDSFYSGLLLGPSVRFDDYPALLRGAGLRPLELIDVSDQVIARSFQL
HHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEECCHHHHHHHHHHH
LAERIRRDKENLDDLLGDELYQRLASTGVDGLREIGYLVVVAERPTE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA