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The map label for this gene is cutS [H]

Identifier: 158316569

GI number: 158316569

Start: 5737616

End: 5738230

Strand: Reverse

Name: cutS [H]

Synonym: Franean1_4805

Alternate gene names: 158316569

Gene position: 5738230-5737616 (Counterclockwise)

Preceding gene: 158316572

Following gene: 158316561

Centisome position: 63.89

GC content: 74.31

Gene sequence:

>615_bases
GTGGCCCTCGCCGACCCGGACACGACGGTCGACTCGCTGCGGGCCGCCTGCCAGGACGTCCTCGCCCTCGGCGAAGCACA
GGAGAGCCTCATCGAGGCGCTGCTCACGCTGGCCGGCGGCGAGCAGGGGGTGGAACACAGAGAACCGTTCGACCTGGCGG
TCGTCGCCCGCGGCGTCCTGCTGACCCGGCGGACCGGAGGCGTCGACGGCACCGGACGGGACGATGGCGTCGAGGTGATC
AGCGCGTTCGGCGCGGCGCCGACGGCCGGCGACCCACGGCTGGTCGAGAGCCTGGTGGCGAACCTGGTCGACAACGCGCT
GCGGCACAACGTCCCCGGCGGACGAGTCGAGATCGTGACGGCGGCTACCAGGCACGGAGCACATCTCACGGCCCGCAACA
CCGGACCGGTCGTCCCACCGGACCAGGTCGAGCGGCTCTTCCAGCCGTTCCAGCAGCTCGGCGGCCAGCGGGTCCGGCGG
GCCGCCGGGCACGGCCTCGGGCTGGCGATCGTCCGCGCCGTCGCGGGCGCGCACGGCGCCACCCTGACCGCGCGCGCCCG
GCCCGAGGGTGGCCTGGACATCGAGGTCCTCTTCCCTGGAGTCAGGATCCCCTGA

Upstream 100 bases:

>100_bases
CGAGCGGCTGGAGGCGGCGTTCGCGTCGCAGCGGCACTTCGTCGCCAACGCCTCCCACGAGCTGCGGACGCCCCTGACCG
CCACGCGGACGGTGCTGCAG

Downstream 100 bases:

>100_bases
GCCAGGCCTAAAGATCCACGCTGTCGTCGTCGACCGGGTCGTCGTCGAGGAGGTAGGCGCCGCCGTCGTCGTCGAGGCCG
AACGAGGCACCACCGGCTCC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MALADPDTTVDSLRAACQDVLALGEAQESLIEALLTLAGGEQGVEHREPFDLAVVARGVLLTRRTGGVDGTGRDDGVEVI
SAFGAAPTAGDPRLVESLVANLVDNALRHNVPGGRVEIVTAATRHGAHLTARNTGPVVPPDQVERLFQPFQQLGGQRVRR
AAGHGLGLAIVRAVAGAHGATLTARARPEGGLDIEVLFPGVRIP

Sequences:

>Translated_204_residues
MALADPDTTVDSLRAACQDVLALGEAQESLIEALLTLAGGEQGVEHREPFDLAVVARGVLLTRRTGGVDGTGRDDGVEVI
SAFGAAPTAGDPRLVESLVANLVDNALRHNVPGGRVEIVTAATRHGAHLTARNTGPVVPPDQVERLFQPFQQLGGQRVRR
AAGHGLGLAIVRAVAGAHGATLTARARPEGGLDIEVLFPGVRIP
>Mature_203_residues
ALADPDTTVDSLRAACQDVLALGEAQESLIEALLTLAGGEQGVEHREPFDLAVVARGVLLTRRTGGVDGTGRDDGVEVIS
AFGAAPTAGDPRLVESLVANLVDNALRHNVPGGRVEIVTAATRHGAHLTARNTGPVVPPDQVERLFQPFQQLGGQRVRRA
AGHGLGLAIVRAVAGAHGATLTARARPEGGLDIEVLFPGVRIP

Specific function: Member of the two-component regulatory system CutS/CutR, involved in the regulation of copper metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=116, Percent_Identity=35.3448275862069, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=192, Percent_Identity=31.25, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788393, Length=110, Percent_Identity=35.4545454545455, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786783, Length=121, Percent_Identity=31.404958677686, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786912, Length=113, Percent_Identity=37.1681415929204, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1786600, Length=181, Percent_Identity=26.5193370165746, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 21125; Mature: 20994

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALADPDTTVDSLRAACQDVLALGEAQESLIEALLTLAGGEQGVEHREPFDLAVVARGVL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LTRRTGGVDGTGRDDGVEVISAFGAAPTAGDPRLVESLVANLVDNALRHNVPGGRVEIVT
HEECCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
AATRHGAHLTARNTGPVVPPDQVERLFQPFQQLGGQRVRRAAGHGLGLAIVRAVAGAHGA
ECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
TLTARARPEGGLDIEVLFPGVRIP
EEEECCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
ALADPDTTVDSLRAACQDVLALGEAQESLIEALLTLAGGEQGVEHREPFDLAVVARGVL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LTRRTGGVDGTGRDDGVEVISAFGAAPTAGDPRLVESLVANLVDNALRHNVPGGRVEIVT
HEECCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
AATRHGAHLTARNTGPVVPPDQVERLFQPFQQLGGQRVRRAAGHGLGLAIVRAVAGAHGA
ECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
TLTARARPEGGLDIEVLFPGVRIP
EEEECCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]