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The map label for this gene is cutL [H]

Identifier: 158316464

GI number: 158316464

Start: 5613718

End: 5616051

Strand: Reverse

Name: cutL [H]

Synonym: Franean1_4699

Alternate gene names: 158316464

Gene position: 5616051-5613718 (Counterclockwise)

Preceding gene: 158316465

Following gene: 158316463

Centisome position: 62.53

GC content: 68.51

Gene sequence:

>2334_bases
ATGAGATTCGTCGGCGAGCGGGTGGCAAGAGTCGAGGACCCGCGGTTGTTGACGGGCCGTGGAAAATTCGTCGACGACGT
GACGTTGCCGCGCATGCTCCATGTCGCTTTCGTACGCAGCCCCATGGCCCACGCTCGGATCAACAGCATCGACACCACGG
CGGCGCGAGCGGTGCCCGGCGTCGTGGCGGTGTTCACCGGCGCCGACCTGGTAGCCGGCTGCAATCCCCTCACGGGATTG
CGCAACGGACCGAACTGGCCGACGTTCCGCGCCTTGCCCACGGACAAGGCAAGGTTCGTCGGCGATCCGCTCGTGATGGT
CGTGGCCGACAGCCGGTACATAGCCGAGGACGCGTGCGAGCTGGTCGACATCGACTACGAGCCGCTTCCGGCGGTGACCG
GTTACGAAGCTGCCCTCGACCCCGCATCACCGGCCATCTTCGACGAACTCGGCGACAACATCGTGGCGACGAGCCCACCC
GTCACCCTGGGTGACATCGATGCCGCCTTCGCCGAGGCCGACCAGGTGGTGCGGGCGACCTTGCGCCAACACCGTGTCGC
CAACGTCCCCCTGGAAACGAGGGGCGGGATCGCCGACTACGACCCGGCCTCGGGGGAGCTGACCTTCATCGCCTCGACCC
AGACCCCGCATGGCCTGCGGCAGGCACTGGCCCAGGCTCTCGACCATCCCCTGGAACGGCTGCGGGTGCTTGCGGGCGAC
GTGGGTGGTGGCTTCGGCCTCAAGGGTGTGGTGGGGCGCGAGGACTTCTGCATCGCGCTGGCCAGCAAGCGGCTCGGCCG
TCCGGTCAAATGGGTGGAGGACCGCAACGAGCACCTTCTCGCGTCCGGCCACGCCCGCGAAGAGAAGATCGACGCGGAAC
TCGCGCTGAAGGCCGACGGCACGCTGCTCGGGTTGAAGGTGAAGCTCGTCCTGGACGGCGGCGCCTACCCGGCGGTGCCG
TTCAGCTGCACGATCTACCCTGAGATGATCTGTACGTCGCTGCCTGGCCCTTACCACATCAAAGCCTACAAATATGAAAG
CGCTGTCGTCGCCAGCAACAAGGCTACGTACGTCGCCTACCGGGGCCCGTGGGAGATGGAGGTGTGGACGCGGGAACGGC
TGCTTGACATCGCGGCCCACGAGCTGGGGCTCGACCCCGCCGACATCCGGCGCCGGAACCTGGTGGCCGGCGAGCCCGGC
GACCAGATCATCACTGGCCGAGGCCTGGAGGGCATCACATCACGCCGCTCCCTTGAGCAGGCCCTGGACCTCGTCGATTA
CGACGGGTTCCGGAAGGAGCAGGTAGCCGCGCGTGCCGCGGGCCGCTACCTCGGCATCGGGTTCGCCATCTTCATGGAAG
CGGCGCCCGGGCCGCCGGAGTTGCGGGGCAAAGGTGCGCCCTTCGGCGGCGAACAGGCGAAGGCGGCGCTCCAGGCCGAC
GGCCATCTCCTCGTGACCACCGGTCAGGCCCCGCACGGCCAGGGCCACGAGACGACGCTCGCCCAGGTCGCGGCCGACCA
GATGGGTATTCCGCTGGACCACGTGCGGGTGGTCCACGGCGACACGCGTCAGACCCCGTTCAACCTCATCGGCACCGGCG
GCAGCCGGGCCGGCACGTGGGCGACGGGTGCCGTGATCGTGACGACCAGGCGGCTGAAGGAAAAGGTGCTGGACATCGCG
GCCCACCGGCTGCAGATCGATCCTGGCGACCTCGACATCGTCGACGGGATGGTGACGCCGAAGGGGGCGCCGGACAAGGC
GATCCCGCTGGCCGACGTGGCGAAGCTGGCGATGATGGCGCCCATGTTCCTCCCGCCGGGCACCGACGTGTCCTTGACGG
CGCAGGAGCGCTTCGACGGGTCCGCCGTCACCAGCAGCGGTTGGTCGGGCGGCGCACATGTCTGCACCGTCGAGGTGGAC
ATCGCCACGGGGCAGGTCCGGATACTTCGTTACGTCGTCGTCGAGGACTGCGGACGGGTGGTCAACCCGGCGATCGTCGA
GGGCCAGATCTGCGGCGGTATCGCGCAGGGCATCGGCGAGGTGCTGTACGAGAACGCCGCCTACGACGCCGACGGCAACT
TCCTCGCCGCCACGTTCATGGACTACCTGCTCCCGACCGCCGCCGAGATCCCGCACATCGAGATCGAACACATCGATTCC
GCAGGCCTCGGCGACTTCGACTTCCACGGTGTCGGCGAAGGCGGGGCGCTGGCCGCCCCGGCGACGCTGACCAACGCCGT
GGCGGACGCTCTGCTGCCCTTCGGAGCCCGGGTGGTCGACCAGTACCTTCCCCCAGCGAAGATCCTCGAGCTCGCGGGCG
TGATCTCTGCCTGA

Upstream 100 bases:

>100_bases
CCGTTCTGGTCCCCGGCTGCGGCTGCGGACTCGTAGAGCGAGGCAAAAGGTCGGCGCCGGCGTTCGGTGGCGCGGCGGTA
CCTGAGCCGGTGTTGTACCG

Downstream 100 bases:

>100_bases
CACTCGTCCACCAGTTGCCCGAAACAGTCCGCAGCCATAGCGGAAGGTGGCCTTCGTGAGCCTCCGTACCACGTCCCCGG
CACTGTCCTACCGTTGCGCG

Product: carbon-monoxide dehydrogenase (acceptor)

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MRFVGERVARVEDPRLLTGRGKFVDDVTLPRMLHVAFVRSPMAHARINSIDTTAARAVPGVVAVFTGADLVAGCNPLTGL
RNGPNWPTFRALPTDKARFVGDPLVMVVADSRYIAEDACELVDIDYEPLPAVTGYEAALDPASPAIFDELGDNIVATSPP
VTLGDIDAAFAEADQVVRATLRQHRVANVPLETRGGIADYDPASGELTFIASTQTPHGLRQALAQALDHPLERLRVLAGD
VGGGFGLKGVVGREDFCIALASKRLGRPVKWVEDRNEHLLASGHAREEKIDAELALKADGTLLGLKVKLVLDGGAYPAVP
FSCTIYPEMICTSLPGPYHIKAYKYESAVVASNKATYVAYRGPWEMEVWTRERLLDIAAHELGLDPADIRRRNLVAGEPG
DQIITGRGLEGITSRRSLEQALDLVDYDGFRKEQVAARAAGRYLGIGFAIFMEAAPGPPELRGKGAPFGGEQAKAALQAD
GHLLVTTGQAPHGQGHETTLAQVAADQMGIPLDHVRVVHGDTRQTPFNLIGTGGSRAGTWATGAVIVTTRRLKEKVLDIA
AHRLQIDPGDLDIVDGMVTPKGAPDKAIPLADVAKLAMMAPMFLPPGTDVSLTAQERFDGSAVTSSGWSGGAHVCTVEVD
IATGQVRILRYVVVEDCGRVVNPAIVEGQICGGIAQGIGEVLYENAAYDADGNFLAATFMDYLLPTAAEIPHIEIEHIDS
AGLGDFDFHGVGEGGALAAPATLTNAVADALLPFGARVVDQYLPPAKILELAGVISA

Sequences:

>Translated_777_residues
MRFVGERVARVEDPRLLTGRGKFVDDVTLPRMLHVAFVRSPMAHARINSIDTTAARAVPGVVAVFTGADLVAGCNPLTGL
RNGPNWPTFRALPTDKARFVGDPLVMVVADSRYIAEDACELVDIDYEPLPAVTGYEAALDPASPAIFDELGDNIVATSPP
VTLGDIDAAFAEADQVVRATLRQHRVANVPLETRGGIADYDPASGELTFIASTQTPHGLRQALAQALDHPLERLRVLAGD
VGGGFGLKGVVGREDFCIALASKRLGRPVKWVEDRNEHLLASGHAREEKIDAELALKADGTLLGLKVKLVLDGGAYPAVP
FSCTIYPEMICTSLPGPYHIKAYKYESAVVASNKATYVAYRGPWEMEVWTRERLLDIAAHELGLDPADIRRRNLVAGEPG
DQIITGRGLEGITSRRSLEQALDLVDYDGFRKEQVAARAAGRYLGIGFAIFMEAAPGPPELRGKGAPFGGEQAKAALQAD
GHLLVTTGQAPHGQGHETTLAQVAADQMGIPLDHVRVVHGDTRQTPFNLIGTGGSRAGTWATGAVIVTTRRLKEKVLDIA
AHRLQIDPGDLDIVDGMVTPKGAPDKAIPLADVAKLAMMAPMFLPPGTDVSLTAQERFDGSAVTSSGWSGGAHVCTVEVD
IATGQVRILRYVVVEDCGRVVNPAIVEGQICGGIAQGIGEVLYENAAYDADGNFLAATFMDYLLPTAAEIPHIEIEHIDS
AGLGDFDFHGVGEGGALAAPATLTNAVADALLPFGARVVDQYLPPAKILELAGVISA
>Mature_777_residues
MRFVGERVARVEDPRLLTGRGKFVDDVTLPRMLHVAFVRSPMAHARINSIDTTAARAVPGVVAVFTGADLVAGCNPLTGL
RNGPNWPTFRALPTDKARFVGDPLVMVVADSRYIAEDACELVDIDYEPLPAVTGYEAALDPASPAIFDELGDNIVATSPP
VTLGDIDAAFAEADQVVRATLRQHRVANVPLETRGGIADYDPASGELTFIASTQTPHGLRQALAQALDHPLERLRVLAGD
VGGGFGLKGVVGREDFCIALASKRLGRPVKWVEDRNEHLLASGHAREEKIDAELALKADGTLLGLKVKLVLDGGAYPAVP
FSCTIYPEMICTSLPGPYHIKAYKYESAVVASNKATYVAYRGPWEMEVWTRERLLDIAAHELGLDPADIRRRNLVAGEPG
DQIITGRGLEGITSRRSLEQALDLVDYDGFRKEQVAARAAGRYLGIGFAIFMEAAPGPPELRGKGAPFGGEQAKAALQAD
GHLLVTTGQAPHGQGHETTLAQVAADQMGIPLDHVRVVHGDTRQTPFNLIGTGGSRAGTWATGAVIVTTRRLKEKVLDIA
AHRLQIDPGDLDIVDGMVTPKGAPDKAIPLADVAKLAMMAPMFLPPGTDVSLTAQERFDGSAVTSSGWSGGAHVCTVEVD
IATGQVRILRYVVVEDCGRVVNPAIVEGQICGGIAQGIGEVLYENAAYDADGNFLAATFMDYLLPTAAEIPHIEIEHIDS
AGLGDFDFHGVGEGGALAAPATLTNAVADALLPFGARVVDQYLPPAKILELAGVISA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=722, Percent_Identity=27.0083102493075, Blast_Score=169, Evalue=9e-42,
Organism=Homo sapiens, GI71773480, Length=761, Percent_Identity=24.0473061760841, Blast_Score=132, Evalue=1e-30,
Organism=Escherichia coli, GI1789230, Length=787, Percent_Identity=30.7496823379924, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI1789246, Length=829, Percent_Identity=25.8142340168878, Blast_Score=189, Evalue=6e-49,
Organism=Escherichia coli, GI1786478, Length=796, Percent_Identity=25.7537688442211, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=755, Percent_Identity=26.0927152317881, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17539860, Length=752, Percent_Identity=23.936170212766, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=741, Percent_Identity=22.1322537112011, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17737937, Length=708, Percent_Identity=26.6949152542373, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24647199, Length=719, Percent_Identity=23.643949930459, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24647193, Length=711, Percent_Identity=24.6132208157525, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24647195, Length=779, Percent_Identity=22.8498074454429, Blast_Score=113, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24647197, Length=765, Percent_Identity=22.8758169934641, Blast_Score=112, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 82407; Mature: 82407

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVGERVARVEDPRLLTGRGKFVDDVTLPRMLHVAFVRSPMAHARINSIDTTAARAVPG
CCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCC
VVAVFTGADLVAGCNPLTGLRNGPNWPTFRALPTDKARFVGDPLVMVVADSRYIAEDACE
EEEEEECCHHHHCCCCCCCCCCCCCCCCEECCCCCCHHHCCCCEEEEEECCCHHHHHHHH
LVDIDYEPLPAVTGYEAALDPASPAIFDELGDNIVATSPPVTLGDIDAAFAEADQVVRAT
EEECCCCCCCCCCCCHHCCCCCCCHHHHHHCCCEEECCCCCEECCCHHHHHHHHHHHHHH
LRQHRVANVPLETRGGIADYDPASGELTFIASTQTPHGLRQALAQALDHPLERLRVLAGD
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
VGGGFGLKGVVGREDFCIALASKRLGRPVKWVEDRNEHLLASGHAREEKIDAELALKADG
CCCCCCCCCCCCCCCHHEEEHHHHHCCCCHHHCCCCCEEEECCCCCHHHCCCEEEEECCC
TLLGLKVKLVLDGGAYPAVPFSCTIYPEMICTSLPGPYHIKAYKYESAVVASNKATYVAY
EEEEEEEEEEECCCCCCCCCEEEEECHHHHHHCCCCCEEEEEEEECCEEEECCCEEEEEE
RGPWEMEVWTRERLLDIAAHELGLDPADIRRRNLVAGEPGDQIITGRGLEGITSRRSLEQ
CCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHH
ALDLVDYDGFRKEQVAARAAGRYLGIGFAIFMEAAPGPPELRGKGAPFGGEQAKAALQAD
HHHHHCCCCCCHHHHHHHHCCCHHEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
GHLLVTTGQAPHGQGHETTLAQVAADQMGIPLDHVRVVHGDTRQTPFNLIGTGGSRAGTW
CEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCEEEECCCCCCCCE
ATGAVIVTTRRLKEKVLDIAAHRLQIDPGDLDIVDGMVTPKGAPDKAIPLADVAKLAMMA
ECCEEEEEHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHC
PMFLPPGTDVSLTAQERFDGSAVTSSGWSGGAHVCTVEVDIATGQVRILRYVVVEDCGRV
CCCCCCCCCEEEEHHHCCCCCCEECCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHH
VNPAIVEGQICGGIAQGIGEVLYENAAYDADGNFLAATFMDYLLPTAAEIPHIEIEHIDS
CCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCC
AGLGDFDFHGVGEGGALAAPATLTNAVADALLPFGARVVDQYLPPAKILELAGVISA
CCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRFVGERVARVEDPRLLTGRGKFVDDVTLPRMLHVAFVRSPMAHARINSIDTTAARAVPG
CCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCC
VVAVFTGADLVAGCNPLTGLRNGPNWPTFRALPTDKARFVGDPLVMVVADSRYIAEDACE
EEEEEECCHHHHCCCCCCCCCCCCCCCCEECCCCCCHHHCCCCEEEEEECCCHHHHHHHH
LVDIDYEPLPAVTGYEAALDPASPAIFDELGDNIVATSPPVTLGDIDAAFAEADQVVRAT
EEECCCCCCCCCCCCHHCCCCCCCHHHHHHCCCEEECCCCCEECCCHHHHHHHHHHHHHH
LRQHRVANVPLETRGGIADYDPASGELTFIASTQTPHGLRQALAQALDHPLERLRVLAGD
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
VGGGFGLKGVVGREDFCIALASKRLGRPVKWVEDRNEHLLASGHAREEKIDAELALKADG
CCCCCCCCCCCCCCCHHEEEHHHHHCCCCHHHCCCCCEEEECCCCCHHHCCCEEEEECCC
TLLGLKVKLVLDGGAYPAVPFSCTIYPEMICTSLPGPYHIKAYKYESAVVASNKATYVAY
EEEEEEEEEEECCCCCCCCCEEEEECHHHHHHCCCCCEEEEEEEECCEEEECCCEEEEEE
RGPWEMEVWTRERLLDIAAHELGLDPADIRRRNLVAGEPGDQIITGRGLEGITSRRSLEQ
CCCCCEEHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHH
ALDLVDYDGFRKEQVAARAAGRYLGIGFAIFMEAAPGPPELRGKGAPFGGEQAKAALQAD
HHHHHCCCCCCHHHHHHHHCCCHHEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
GHLLVTTGQAPHGQGHETTLAQVAADQMGIPLDHVRVVHGDTRQTPFNLIGTGGSRAGTW
CEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCEEEECCCCCCCCE
ATGAVIVTTRRLKEKVLDIAAHRLQIDPGDLDIVDGMVTPKGAPDKAIPLADVAKLAMMA
ECCEEEEEHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHC
PMFLPPGTDVSLTAQERFDGSAVTSSGWSGGAHVCTVEVDIATGQVRILRYVVVEDCGRV
CCCCCCCCCEEEEHHHCCCCCCEECCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHH
VNPAIVEGQICGGIAQGIGEVLYENAAYDADGNFLAATFMDYLLPTAAEIPHIEIEHIDS
CCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCC
AGLGDFDFHGVGEGGALAAPATLTNAVADALLPFGARVVDQYLPPAKILELAGVISA
CCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]