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The map label for this gene is dgoD [H]

Identifier: 158316443

GI number: 158316443

Start: 5587369

End: 5588532

Strand: Reverse

Name: dgoD [H]

Synonym: Franean1_4678

Alternate gene names: 158316443

Gene position: 5588532-5587369 (Counterclockwise)

Preceding gene: 158316444

Following gene: 158316442

Centisome position: 62.22

GC content: 71.56

Gene sequence:

>1164_bases
ATGAAGATCGCCGACGTGCGGACGCACGTGTACGGGACCCCGTGGCGGGATCTGACCTACGTCCAGGTCTTCACGGACGA
CGGTCTGGTCGGCGTAGGAGAGACCCGGATGCTCGGCCACACCCAGGCGCTGCTGGGCTACCTGGCCGAGGCGACCCGCA
ACCATGTGCTCGGCTCCGATCCGTTCGACATCGAGTCACTGGTCGACCGGATGAAGCGCGGCGACTACGGGCGGGCCGGC
GAGATCGTCATGTCCGGTATCGCGTGCGTCGAGATGGCCTGCTGGGACATCGTCGGCAAGGCGCTGGGGCAGCCGGTGTG
GCGGCTGCTGGGCGGCAAGGTCCGCGACCGGATCAAGGCGTACGCCAACGGCTGGTACACCGTCGAGCGCACCCCCGAGG
AGTTCCACGCGGCGGCGCGGGCGGTGGTGGACCGGGGCTACCGGGCGCTCAAGCTCGACCCGTTCGGGGCCGGCCGGTGG
GAGCTGGACCGGGCCGAACGTCGCCACTCCATCTCCCTGGTCGAGGCGGTGCGCGACGCGGTCGGGCCGGACGTGGAGAT
CCTCGTCGAGATGCACGGGCGGTTCGCCCCACACGAGGCGATCCGGATTGCCGCCTCACTGACCGAGTTCGAGCCGGGCT
GGGTCGAGGAGCCGGTACCACCGGAGAACCTGCGGGCGCTGGCCAAGGCCGCCGCCGGGATCGACGCCCCGGTGGCGACC
GGGGAGCGCATCCACGACCGCACCGAGTTCCGGGAGCTGTTCGACCTCGGCGCGGCCGACATCATCCAGCCCGACATCGG
CCATCTCGGTGGCATCAGCGAGACCCGCAAGCTCGCCGCGACCGCAGAGACCCACTTCACGCTGGTCGCCCCGCACAACG
TCGGCGGCGCGGTTCTCACCGCCGCCAACCTGCACCTGGCCGCCTGCACCCCCAACTTCATGATCCAGGAACACTTCAAC
GACTTCGCCGACGAGGAGGTCAAGCTCGCGGCGCCGGGCCTGCCGCCGGTCGTCGACGGCTACTTCGCCCTGCCGACCGC
ACCCGGCCTCGGCGTCGAGCTGGACGTCGACGTCGTGGCCGCCCACCCGTCCCGCGGCGCCCACTTCGACCTCTACGCCG
ACGGCTGGGAGCTGCGCGGCTCCCGCCCGCCCGGCCGCGGCTGA

Upstream 100 bases:

>100_bases
GGCTGGCCGTCCCGGCGCCACCCGGCGACGCACCGGCCTCGCCGGCCCCACCGGCGACTCCGCCGTCCGCCGCTGTAGAG
GGAACACCGGGGGCAGTGTC

Downstream 100 bases:

>100_bases
CCGTGACCGGACGCGCGGTGTGGATCGACGCGCCGGGCCGGCTGGAGATCCGCCCGGCCGAACCGGTCGCTCCCGGGCCG
GGTGAGGTGCTGGTCCGGGT

Product: mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKIADVRTHVYGTPWRDLTYVQVFTDDGLVGVGETRMLGHTQALLGYLAEATRNHVLGSDPFDIESLVDRMKRGDYGRAG
EIVMSGIACVEMACWDIVGKALGQPVWRLLGGKVRDRIKAYANGWYTVERTPEEFHAAARAVVDRGYRALKLDPFGAGRW
ELDRAERRHSISLVEAVRDAVGPDVEILVEMHGRFAPHEAIRIAASLTEFEPGWVEEPVPPENLRALAKAAAGIDAPVAT
GERIHDRTEFRELFDLGAADIIQPDIGHLGGISETRKLAATAETHFTLVAPHNVGGAVLTAANLHLAACTPNFMIQEHFN
DFADEEVKLAAPGLPPVVDGYFALPTAPGLGVELDVDVVAAHPSRGAHFDLYADGWELRGSRPPGRG

Sequences:

>Translated_387_residues
MKIADVRTHVYGTPWRDLTYVQVFTDDGLVGVGETRMLGHTQALLGYLAEATRNHVLGSDPFDIESLVDRMKRGDYGRAG
EIVMSGIACVEMACWDIVGKALGQPVWRLLGGKVRDRIKAYANGWYTVERTPEEFHAAARAVVDRGYRALKLDPFGAGRW
ELDRAERRHSISLVEAVRDAVGPDVEILVEMHGRFAPHEAIRIAASLTEFEPGWVEEPVPPENLRALAKAAAGIDAPVAT
GERIHDRTEFRELFDLGAADIIQPDIGHLGGISETRKLAATAETHFTLVAPHNVGGAVLTAANLHLAACTPNFMIQEHFN
DFADEEVKLAAPGLPPVVDGYFALPTAPGLGVELDVDVVAAHPSRGAHFDLYADGWELRGSRPPGRG
>Mature_387_residues
MKIADVRTHVYGTPWRDLTYVQVFTDDGLVGVGETRMLGHTQALLGYLAEATRNHVLGSDPFDIESLVDRMKRGDYGRAG
EIVMSGIACVEMACWDIVGKALGQPVWRLLGGKVRDRIKAYANGWYTVERTPEEFHAAARAVVDRGYRALKLDPFGAGRW
ELDRAERRHSISLVEAVRDAVGPDVEILVEMHGRFAPHEAIRIAASLTEFEPGWVEEPVPPENLRALAKAAAGIDAPVAT
GERIHDRTEFRELFDLGAADIIQPDIGHLGGISETRKLAATAETHFTLVAPHNVGGAVLTAANLHLAACTPNFMIQEHFN
DFADEEVKLAAPGLPPVVDGYFALPTAPGLGVELDVDVVAAHPSRGAHFDLYADGWELRGSRPPGRG

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=332, Percent_Identity=25, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI186972148, Length=260, Percent_Identity=24.2307692307692, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI48994953, Length=370, Percent_Identity=33.2432432432432, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1787864, Length=398, Percent_Identity=27.8894472361809, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI226510960, Length=316, Percent_Identity=28.4810126582279, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 42125; Mature: 42125

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIADVRTHVYGTPWRDLTYVQVFTDDGLVGVGETRMLGHTQALLGYLAEATRNHVLGSD
CCCCCCCHHCCCCCCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PFDIESLVDRMKRGDYGRAGEIVMSGIACVEMACWDIVGKALGQPVWRLLGGKVRDRIKA
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHHHHH
YANGWYTVERTPEEFHAAARAVVDRGYRALKLDPFGAGRWELDRAERRHSISLVEAVRDA
HHCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
VGPDVEILVEMHGRFAPHEAIRIAASLTEFEPGWVEEPVPPENLRALAKAAAGIDAPVAT
HCCCCEEHEEHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
GERIHDRTEFRELFDLGAADIIQPDIGHLGGISETRKLAATAETHFTLVAPHNVGGAVLT
CHHHHHHHHHHHHHHCCCHHHCCCCCHHCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEE
AANLHLAACTPNFMIQEHFNDFADEEVKLAAPGLPPVVDGYFALPTAPGLGVELDVDVVA
ECCEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHCCEEECCCCCCCCEEEEEEEEE
AHPSRGAHFDLYADGWELRGSRPPGRG
ECCCCCCEEEEEECCEEECCCCCCCCC
>Mature Secondary Structure
MKIADVRTHVYGTPWRDLTYVQVFTDDGLVGVGETRMLGHTQALLGYLAEATRNHVLGSD
CCCCCCCHHCCCCCCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PFDIESLVDRMKRGDYGRAGEIVMSGIACVEMACWDIVGKALGQPVWRLLGGKVRDRIKA
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHHHHH
YANGWYTVERTPEEFHAAARAVVDRGYRALKLDPFGAGRWELDRAERRHSISLVEAVRDA
HHCCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
VGPDVEILVEMHGRFAPHEAIRIAASLTEFEPGWVEEPVPPENLRALAKAAAGIDAPVAT
HCCCCEEHEEHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
GERIHDRTEFRELFDLGAADIIQPDIGHLGGISETRKLAATAETHFTLVAPHNVGGAVLT
CHHHHHHHHHHHHHHCCCHHHCCCCCHHCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEE
AANLHLAACTPNFMIQEHFNDFADEEVKLAAPGLPPVVDGYFALPTAPGLGVELDVDVVA
ECCEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHCCEEECCCCCCCCEEEEEEEEE
AHPSRGAHFDLYADGWELRGSRPPGRG
ECCCCCCEEEEEECCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA