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The map label for this gene is atoB [H]

Identifier: 158316348

GI number: 158316348

Start: 5459955

End: 5461121

Strand: Reverse

Name: atoB [H]

Synonym: Franean1_4577

Alternate gene names: 158316348

Gene position: 5461121-5459955 (Counterclockwise)

Preceding gene: 158316349

Following gene: 158316347

Centisome position: 60.8

GC content: 74.89

Gene sequence:

>1167_bases
ATGGCCCAGGCCGTGATCGTCAGTGCGGTGCGCACGCCCATCGCGACGTCGTTCAAGGGGACGCTGCGGGACACCTCGGC
CGAGGAGCTGGCCACGGCGGTCGTCCGGGCCGCGGTGGACCGCTCGGGGCTGGCGCCCGAGGACGTCGACGACGTCATCC
TCGCCGAGGAGCTGGCCGGCGGCGGCGACATCGCCAGGTACGCCGCCTTCGCGGCCGGGCTGACGGCGGCGCCGGGCCAG
GCCGTCAACCGCCACTGCGCGGCGAGCCTCGCGGCGGTGGGCAACGCGGCGGCGACGATCCGGGCCGGGATGGACCGCGC
GGTCGTCGCCGGCGGCACCCACTCCTCGTCGATGAACCCCAGGCTGTCGTGGCGGGTGCCCGGGTCGGACGAGCCGCGCG
CCGGGTTCAACCCCACGTTCCCCTACTACGAGGGCGCCACCGACGACGTGACCCTCGCCGTCGGCTGGAACACCGCGCAG
GAGGTGGGCATCACCCGGGCGGAGATGGACGCCTGGGCCAAGCGCTCCCACGACCGGGCGATCGCCGCGATCGACGCCGG
AGTCTTCGACGACGAGATCGTCCCGATCGACGTCGTCGTGGCGGGGGAGAAGGTCCGCTTCGCCGTCGACGAGCACCCGC
GCCGGACGTCCACGCTGGAGAAGCTGGCCACGCTGAAGCCGCTGCACCCCGAGATCGAGGGCTTCGGCATCACCGCGGGG
AACGCGAGCGGCGTGAACGACGCCGCCGCGGCCCTGATGCTGGTCACCGACGACCTCGCCCGGGATCGGGGCCTCACCCC
GCTGGCCCGGGTGCGGGCGTGGGCGGCACTCGGCGTGGCCCCGCACCGCACCGGGATGGCCGGGGTGGAGGTCATCCCGC
GGGTGCTGGAGCGGGCCGGGATCGGGGTGGCCGACGTCGACGCCTGGGAGATCAACGAGGCCTTCGCGTCGGTCCCGATC
GCCGCCTGCCGCCTCCTGGGAATCCCGGACGACCTGGTCAACCAGTACGGCAGTGGCTGCAGTCTCGGGCATCCGGTCGC
GGCCTCCGGAGCGCGGATGCTGACCACCCTGACCCACCACCTGCGCCGGCGCGGCGGCGGGATCGCCGTGGCGGCGATGT
GCGCCGCGGGCGGCCAGGGCGGCGCAGTGGTCATCGAGGCGCCGTGA

Upstream 100 bases:

>100_bases
GCCCGCTCGGCAGCCTGGCTGACGGGCCTGCTCGCCGACCTCGGCGCCTGACAAGCCCAGCGCCTGACAAGCCCACCGTT
CATCGAGGAGAGGTACAGCC

Downstream 100 bases:

>100_bases
GGGTCGGGATGCCGCTGAAGTACTCCGGCGGCTTCACCGAGACCGTCGCGGACCTTCGCGACTTCGAGGCGGCCGGGCTC
GACCTGGTCATGCTCCCGGA

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MAQAVIVSAVRTPIATSFKGTLRDTSAEELATAVVRAAVDRSGLAPEDVDDVILAEELAGGGDIARYAAFAAGLTAAPGQ
AVNRHCAASLAAVGNAAATIRAGMDRAVVAGGTHSSSMNPRLSWRVPGSDEPRAGFNPTFPYYEGATDDVTLAVGWNTAQ
EVGITRAEMDAWAKRSHDRAIAAIDAGVFDDEIVPIDVVVAGEKVRFAVDEHPRRTSTLEKLATLKPLHPEIEGFGITAG
NASGVNDAAAALMLVTDDLARDRGLTPLARVRAWAALGVAPHRTGMAGVEVIPRVLERAGIGVADVDAWEINEAFASVPI
AACRLLGIPDDLVNQYGSGCSLGHPVAASGARMLTTLTHHLRRRGGGIAVAAMCAAGGQGGAVVIEAP

Sequences:

>Translated_388_residues
MAQAVIVSAVRTPIATSFKGTLRDTSAEELATAVVRAAVDRSGLAPEDVDDVILAEELAGGGDIARYAAFAAGLTAAPGQ
AVNRHCAASLAAVGNAAATIRAGMDRAVVAGGTHSSSMNPRLSWRVPGSDEPRAGFNPTFPYYEGATDDVTLAVGWNTAQ
EVGITRAEMDAWAKRSHDRAIAAIDAGVFDDEIVPIDVVVAGEKVRFAVDEHPRRTSTLEKLATLKPLHPEIEGFGITAG
NASGVNDAAAALMLVTDDLARDRGLTPLARVRAWAALGVAPHRTGMAGVEVIPRVLERAGIGVADVDAWEINEAFASVPI
AACRLLGIPDDLVNQYGSGCSLGHPVAASGARMLTTLTHHLRRRGGGIAVAAMCAAGGQGGAVVIEAP
>Mature_387_residues
AQAVIVSAVRTPIATSFKGTLRDTSAEELATAVVRAAVDRSGLAPEDVDDVILAEELAGGGDIARYAAFAAGLTAAPGQA
VNRHCAASLAAVGNAAATIRAGMDRAVVAGGTHSSSMNPRLSWRVPGSDEPRAGFNPTFPYYEGATDDVTLAVGWNTAQE
VGITRAEMDAWAKRSHDRAIAAIDAGVFDDEIVPIDVVVAGEKVRFAVDEHPRRTSTLEKLATLKPLHPEIEGFGITAGN
ASGVNDAAAALMLVTDDLARDRGLTPLARVRAWAALGVAPHRTGMAGVEVIPRVLERAGIGVADVDAWEINEAFASVPIA
ACRLLGIPDDLVNQYGSGCSLGHPVAASGARMLTTLTHHLRRRGGGIAVAAMCAAGGQGGAVVIEAP

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=390, Percent_Identity=37.1794871794872, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI167614485, Length=390, Percent_Identity=35.1282051282051, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI4557237, Length=395, Percent_Identity=35.4430379746835, Blast_Score=198, Evalue=9e-51,
Organism=Homo sapiens, GI4501853, Length=401, Percent_Identity=35.1620947630923, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI4504327, Length=426, Percent_Identity=29.5774647887324, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI194353979, Length=394, Percent_Identity=27.1573604060914, Blast_Score=116, Evalue=3e-26,
Organism=Escherichia coli, GI1788554, Length=403, Percent_Identity=39.7022332506204, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI87082165, Length=395, Percent_Identity=38.4810126582278, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787663, Length=406, Percent_Identity=38.1773399014778, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI48994986, Length=401, Percent_Identity=34.1645885286783, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1788683, Length=426, Percent_Identity=31.4553990610329, Blast_Score=146, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI133906874, Length=396, Percent_Identity=37.1212121212121, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI25147385, Length=393, Percent_Identity=34.8600508905852, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17535921, Length=393, Percent_Identity=33.587786259542, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17551802, Length=429, Percent_Identity=31.4685314685315, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17535917, Length=396, Percent_Identity=29.040404040404, Blast_Score=131, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6325229, Length=408, Percent_Identity=33.8235294117647, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322031, Length=399, Percent_Identity=31.328320802005, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24655093, Length=393, Percent_Identity=35.6234096692112, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI17648125, Length=391, Percent_Identity=32.9923273657289, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24640423, Length=403, Percent_Identity=33.4987593052109, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI17137578, Length=424, Percent_Identity=30.6603773584906, Blast_Score=145, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 39939; Mature: 39807

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAVIVSAVRTPIATSFKGTLRDTSAEELATAVVRAAVDRSGLAPEDVDDVILAEELAG
CCCHHHHHHHHCCHHHCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
GGDIARYAAFAAGLTAAPGQAVNRHCAASLAAVGNAAATIRAGMDRAVVAGGTHSSSMNP
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCCC
RLSWRVPGSDEPRAGFNPTFPYYEGATDDVTLAVGWNTAQEVGITRAEMDAWAKRSHDRA
EEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCHHHHHHHHHHHCCCCE
IAAIDAGVFDDEIVPIDVVVAGEKVRFAVDEHPRRTSTLEKLATLKPLHPEIEGFGITAG
EEEEECCCCCCCCEEEEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEECC
NASGVNDAAAALMLVTDDLARDRGLTPLARVRAWAALGVAPHRTGMAGVEVIPRVLERAG
CCCCCCHHHHEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
IGVADVDAWEINEAFASVPIAACRLLGIPDDLVNQYGSGCSLGHPVAASGARMLTTLTHH
CCEECCCHHHHHHHHHHCHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHCCHHHHHHHHHH
LRRRGGGIAVAAMCAAGGQGGAVVIEAP
HHHCCCCEEEEEEHHCCCCCCEEEEECC
>Mature Secondary Structure 
AQAVIVSAVRTPIATSFKGTLRDTSAEELATAVVRAAVDRSGLAPEDVDDVILAEELAG
CCHHHHHHHHCCHHHCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
GGDIARYAAFAAGLTAAPGQAVNRHCAASLAAVGNAAATIRAGMDRAVVAGGTHSSSMNP
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCCC
RLSWRVPGSDEPRAGFNPTFPYYEGATDDVTLAVGWNTAQEVGITRAEMDAWAKRSHDRA
EEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCHHHHHHHHHHHCCCCE
IAAIDAGVFDDEIVPIDVVVAGEKVRFAVDEHPRRTSTLEKLATLKPLHPEIEGFGITAG
EEEEECCCCCCCCEEEEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEECC
NASGVNDAAAALMLVTDDLARDRGLTPLARVRAWAALGVAPHRTGMAGVEVIPRVLERAG
CCCCCCHHHHEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
IGVADVDAWEINEAFASVPIAACRLLGIPDDLVNQYGSGCSLGHPVAASGARMLTTLTHH
CCEECCCHHHHHHHHHHCHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHCCHHHHHHHHHH
LRRRGGGIAVAAMCAAGGQGGAVVIEAP
HHHCCCCEEEEEEHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]