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The map label for this gene is fabG [C]

Identifier: 158316317

GI number: 158316317

Start: 5421088

End: 5421864

Strand: Reverse

Name: fabG [C]

Synonym: Franean1_4544

Alternate gene names: 158316317

Gene position: 5421864-5421088 (Counterclockwise)

Preceding gene: 158316321

Following gene: 158316316

Centisome position: 60.36

GC content: 68.34

Gene sequence:

>777_bases
GTGGTGAGGCAGACGGATATCAGAATGAGCATCTCAGGCATCCACGCGCTCATGGCCGCGCCCTACGGTTCATCCATGAA
CCTCTCTGGAAGCATCGCCCTCGTCACCGGCGCGAACCGCGGCATCGGCCGCCACTTCGTCGAACAGCTCCACGACCGGG
GGGCGTCGAAGGTCTACGCCACGGCGCGCAACCCCCGGTCGGCCGACCTCCCCGGTGTCGAGACGCTGCCGCTCGACATC
ACCGACCCGGACTCGGTCGCCGCGGCCGCCGCCGCGGCATCCGACGTCACGCTGCTGGTCAACAACGCCGGCGTGTCCAC
CGCGCAGAATCTCGTCACCGGCGATCTGACGAAGATCCGTCTTGAGATGGACACCCACTTCTACGGAACCCTCGCGATGG
TGCGCGCGTTCGCCCCGGTGCTCGCCGGCAACGGCGGCGGCGCGGTCCTCAACGTCCTTTCCAGGCTGTCCTGGCTGTCC
TATCTCGGGGCCAACGCCTACAGCGCGGCCAAGGCCGCGGAGTGGAGCCTGACCAACGGAATCCGCCTGGAGCTGCGCGA
GCAGGGCACCCTCGTCACGGGTCTGGTCCTGAGCAGCACAGACACCGACATGATGGCCGGCTGGGACATCCCGAAGAACG
ATCCGGCCGATGTCGTACGTGCGGCGTTGGACGGCCTGGAGGCCGGGCGGTTCGAGATCCTCGCCGACCGGGACAGTGCC
GAGGCCAAGGCGGCGCTCAGCACCGACCCGGGTGTCCTGTACGCCCAGACCGGATGA

Upstream 100 bases:

>100_bases
TCCCCGGCCTCGATCCTCGCCCCGAGGGTGCCGCGAACCCCCGAGACCGCCAGCACGTCGGCGAGGACATCCACGGACGC
AGCGTACCGGGAGGCCTCAT

Downstream 100 bases:

>100_bases
CGGCCCGCACGCGCGGAACCTTCCGTTTCCTCGGGACGAGACTCGCCGCCGTCGGCTCCTTGCTGACCGAGTCGGCATCT
CTCCGGCGACGCGGTCATCG

Product: short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MVRQTDIRMSISGIHALMAAPYGSSMNLSGSIALVTGANRGIGRHFVEQLHDRGASKVYATARNPRSADLPGVETLPLDI
TDPDSVAAAAAAASDVTLLVNNAGVSTAQNLVTGDLTKIRLEMDTHFYGTLAMVRAFAPVLAGNGGGAVLNVLSRLSWLS
YLGANAYSAAKAAEWSLTNGIRLELREQGTLVTGLVLSSTDTDMMAGWDIPKNDPADVVRAALDGLEAGRFEILADRDSA
EAKAALSTDPGVLYAQTG

Sequences:

>Translated_258_residues
MVRQTDIRMSISGIHALMAAPYGSSMNLSGSIALVTGANRGIGRHFVEQLHDRGASKVYATARNPRSADLPGVETLPLDI
TDPDSVAAAAAAASDVTLLVNNAGVSTAQNLVTGDLTKIRLEMDTHFYGTLAMVRAFAPVLAGNGGGAVLNVLSRLSWLS
YLGANAYSAAKAAEWSLTNGIRLELREQGTLVTGLVLSSTDTDMMAGWDIPKNDPADVVRAALDGLEAGRFEILADRDSA
EAKAALSTDPGVLYAQTG
>Mature_258_residues
MVRQTDIRMSISGIHALMAAPYGSSMNLSGSIALVTGANRGIGRHFVEQLHDRGASKVYATARNPRSADLPGVETLPLDI
TDPDSVAAAAAAASDVTLLVNNAGVSTAQNLVTGDLTKIRLEMDTHFYGTLAMVRAFAPVLAGNGGGAVLNVLSRLSWLS
YLGANAYSAAKAAEWSLTNGIRLELREQGTLVTGLVLSSTDTDMMAGWDIPKNDPADVVRAALDGLEAGRFEILADRDSA
EAKAALSTDPGVLYAQTG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI1787335, Length=194, Percent_Identity=31.9587628865979, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI72001658, Length=210, Percent_Identity=29.0476190476191, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643142, Length=169, Percent_Identity=36.094674556213, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 26914; Mature: 26914

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRQTDIRMSISGIHALMAAPYGSSMNLSGSIALVTGANRGIGRHFVEQLHDRGASKVYA
CCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEE
TARNPRSADLPGVETLPLDITDPDSVAAAAAAASDVTLLVNNAGVSTAQNLVTGDLTKIR
ECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCEEEEE
LEMDTHFYGTLAMVRAFAPVLAGNGGGAVLNVLSRLSWLSYLGANAYSAAKAAEWSLTNG
EEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCEECCCC
IRLELREQGTLVTGLVLSSTDTDMMAGWDIPKNDPADVVRAALDGLEAGRFEILADRDSA
EEEEEECCCCEEEEEEEECCCCCCEECCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCC
EAKAALSTDPGVLYAQTG
CHHEEECCCCCEEEEECC
>Mature Secondary Structure
MVRQTDIRMSISGIHALMAAPYGSSMNLSGSIALVTGANRGIGRHFVEQLHDRGASKVYA
CCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEE
TARNPRSADLPGVETLPLDITDPDSVAAAAAAASDVTLLVNNAGVSTAQNLVTGDLTKIR
ECCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCEEEEE
LEMDTHFYGTLAMVRAFAPVLAGNGGGAVLNVLSRLSWLSYLGANAYSAAKAAEWSLTNG
EEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCEECCCC
IRLELREQGTLVTGLVLSSTDTDMMAGWDIPKNDPADVVRAALDGLEAGRFEILADRDSA
EEEEEECCCCEEEEEEEECCCCCCEECCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCC
EAKAALSTDPGVLYAQTG
CHHEEECCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA