| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
Click here to switch to the map view.
The map label for this gene is lcfB [H]
Identifier: 158316256
GI number: 158316256
Start: 5346623
End: 5348143
Strand: Reverse
Name: lcfB [H]
Synonym: Franean1_4481
Alternate gene names: 158316256
Gene position: 5348143-5346623 (Counterclockwise)
Preceding gene: 158316258
Following gene: 158316255
Centisome position: 59.54
GC content: 64.04
Gene sequence:
>1521_bases ATGACGAATAGCACCAGGAGTCCCGCATCGTTAGGTCGGACGTTGCTTGCGATAGCTGCTGACCGGCCAGCTCACCCGGC GGTAACCACCCGGTCGGGGTCGACTTCCTACCGGGAGCTGGCGGACGGTGCGCTGCGCGTCGCGGCAGCACTGACGGTGC AGGGGCTCGGTCTTGGCGACCGAATAGCGATCCTGGCTCGTAACGATCTACCCTACGTCGAGCTCATCTACGGCGCGGAC TTTGTCGGTGCGGTGGTCGTCGGGATCAATTGTCGGCTCTCGCCGGCGGAGGTTGCCGATATTCTCGACGACTGCCAGCC CAGCCTTGTGTTCGTCGCGGACGAGTACCTGCCGCTGCTGGGTTCCGCCGCCGCGGGCGTCCTCCGGGTGTCTCTTGATC GCGACTACCGGACATGGTGCGGCACCGGGGACATGACGCGGTTCGTGCCGCGGGTCGGTTACGCCGACAGTGTGGTACTC ATGGTCTACACCAGCGGCACCACCGGTCGGTCGAAAGGTGTGCGACTGACCGAGGCCAACATCACGGCCGCCCTCGCCGC GAACAGAGATGTCTGGTTCGTTGGCCCGGAGATCCGGGCGCTGGCGCTTTTTCCGCTGTTTAATATCAGCGGTTCGATCT TTCTGCTCTCGATCTTACATGTCGGCGGTGAAGTCGTCATTGCCGAGAACGCGTCAGGCGCCACCATCCTGGAACTTCTC GGGGCGAGGCGCATTACCCACGCGCTGTTCGTGGCGGCGATGATCGTCGCGCTGCTTGATCAACCGGCCGACGACGAGAT CGACCTGTCCAGCCTGCGAGTACTGATCTATGGTGCCGCTCCGTCTTCGGCGGCCGTGATCGACCGGGCTATGCGGCGGC TGCCGACCTGTGATTTCTTTCAGGGATACGGGATGACGGAGACCTGTGGCGGCATCGCGATGACGCCGCCGCATCGATAC GGCGAAGAGATCGCGCCGGCATCGGTGGGGCGAGCCATACCATCCTATGAGATTCGGATTGTGGATCCGGTCAGGCGCAC CGACCTGCCGGTTGGTGTGGAAGGCGAGATCTGGGCGCGCGGGCCACAGAACACCATCGGCTACTGGAACCGGGCCGAGG AGACCGATCGTCTGCTCGCCGCGGACGGGTGGCTTCGTACCGGTGATGTCGGTGTCCTAGACGCCGCTCACAACCTCTAT GTCGTAGACCGCCTCAAAGACATGATTATTTCGGGTGGGTTCAACGTCTATTCGCTCGAGGTCGAGCAGATCCTGGTCGG CCACCCGGATGTCGGTGATGCGGCGGTGTTCGGCGTGCCCGACGAGCGTTGGGGCGAGACCGTGGTGGCCGTGGTGACCC TGCGTCCGGGCGCCACCTGCGTCCCGGCCGACCTGAGTGAGTTCGCCCGGGCGCGGTTGGCCCACTTCAAATGCCCGCGG CGGATCGAGATTCTCGACGAACTTCCGAGGAATGCGGCCGGAAAGATCCTCAAAAGAGAGCTTCGCGGCCGGTTCAGCTG A
Upstream 100 bases:
>100_bases ACCCGGGGTGGAGCCGCCGGATCGGTGTGAAAAATTGCGTGAATGACCAGATCGGGAAGCCAGAAATACCCGAGTCGAGT TCGGCATGGGGAGTGCGGCG
Downstream 100 bases:
>100_bases ACCCGAGTTGGCACGTAGACCCAACCATGATGCAGGCATCGTGGTGAAATCATGGAGGAACGCTCATGGCCGAGTTTCGT TTTGGCAACCGGGTTGCCCT
Product: AMP-dependent synthetase and ligase
Products: NA
Alternate protein names: Long-chain acyl-CoA synthetase [H]
Number of amino acids: Translated: 506; Mature: 505
Protein sequence:
>506_residues MTNSTRSPASLGRTLLAIAADRPAHPAVTTRSGSTSYRELADGALRVAAALTVQGLGLGDRIAILARNDLPYVELIYGAD FVGAVVVGINCRLSPAEVADILDDCQPSLVFVADEYLPLLGSAAAGVLRVSLDRDYRTWCGTGDMTRFVPRVGYADSVVL MVYTSGTTGRSKGVRLTEANITAALAANRDVWFVGPEIRALALFPLFNISGSIFLLSILHVGGEVVIAENASGATILELL GARRITHALFVAAMIVALLDQPADDEIDLSSLRVLIYGAAPSSAAVIDRAMRRLPTCDFFQGYGMTETCGGIAMTPPHRY GEEIAPASVGRAIPSYEIRIVDPVRRTDLPVGVEGEIWARGPQNTIGYWNRAEETDRLLAADGWLRTGDVGVLDAAHNLY VVDRLKDMIISGGFNVYSLEVEQILVGHPDVGDAAVFGVPDERWGETVVAVVTLRPGATCVPADLSEFARARLAHFKCPR RIEILDELPRNAAGKILKRELRGRFS
Sequences:
>Translated_506_residues MTNSTRSPASLGRTLLAIAADRPAHPAVTTRSGSTSYRELADGALRVAAALTVQGLGLGDRIAILARNDLPYVELIYGAD FVGAVVVGINCRLSPAEVADILDDCQPSLVFVADEYLPLLGSAAAGVLRVSLDRDYRTWCGTGDMTRFVPRVGYADSVVL MVYTSGTTGRSKGVRLTEANITAALAANRDVWFVGPEIRALALFPLFNISGSIFLLSILHVGGEVVIAENASGATILELL GARRITHALFVAAMIVALLDQPADDEIDLSSLRVLIYGAAPSSAAVIDRAMRRLPTCDFFQGYGMTETCGGIAMTPPHRY GEEIAPASVGRAIPSYEIRIVDPVRRTDLPVGVEGEIWARGPQNTIGYWNRAEETDRLLAADGWLRTGDVGVLDAAHNLY VVDRLKDMIISGGFNVYSLEVEQILVGHPDVGDAAVFGVPDERWGETVVAVVTLRPGATCVPADLSEFARARLAHFKCPR RIEILDELPRNAAGKILKRELRGRFS >Mature_505_residues TNSTRSPASLGRTLLAIAADRPAHPAVTTRSGSTSYRELADGALRVAAALTVQGLGLGDRIAILARNDLPYVELIYGADF VGAVVVGINCRLSPAEVADILDDCQPSLVFVADEYLPLLGSAAAGVLRVSLDRDYRTWCGTGDMTRFVPRVGYADSVVLM VYTSGTTGRSKGVRLTEANITAALAANRDVWFVGPEIRALALFPLFNISGSIFLLSILHVGGEVVIAENASGATILELLG ARRITHALFVAAMIVALLDQPADDEIDLSSLRVLIYGAAPSSAAVIDRAMRRLPTCDFFQGYGMTETCGGIAMTPPHRYG EEIAPASVGRAIPSYEIRIVDPVRRTDLPVGVEGEIWARGPQNTIGYWNRAEETDRLLAADGWLRTGDVGVLDAAHNLYV VDRLKDMIISGGFNVYSLEVEQILVGHPDVGDAAVFGVPDERWGETVVAVVTLRPGATCVPADLSEFARARLAHFKCPRR IEILDELPRNAAGKILKRELRGRFS
Specific function: Involved in the degradation of long-chain fatty acids [H]
COG id: COG0318
COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
Gene ontology:
Cell location: Partially Membrane-Associated [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]
Homologues:
Organism=Homo sapiens, GI187761345, Length=520, Percent_Identity=30.5769230769231, Blast_Score=198, Evalue=1e-50, Organism=Homo sapiens, GI187761343, Length=520, Percent_Identity=30.5769230769231, Blast_Score=198, Evalue=1e-50, Organism=Homo sapiens, GI156151445, Length=548, Percent_Identity=26.0948905109489, Blast_Score=164, Evalue=1e-40, Organism=Homo sapiens, GI42544132, Length=531, Percent_Identity=25.2354048964218, Blast_Score=126, Evalue=4e-29, Organism=Homo sapiens, GI122937307, Length=529, Percent_Identity=26.0869565217391, Blast_Score=124, Evalue=2e-28, Organism=Homo sapiens, GI115511026, Length=499, Percent_Identity=24.6492985971944, Blast_Score=104, Evalue=2e-22, Organism=Homo sapiens, GI38505220, Length=530, Percent_Identity=25.8490566037736, Blast_Score=102, Evalue=1e-21, Organism=Homo sapiens, GI58082049, Length=503, Percent_Identity=24.0556660039761, Blast_Score=92, Evalue=9e-19, Organism=Homo sapiens, GI157311624, Length=501, Percent_Identity=23.1536926147705, Blast_Score=92, Evalue=1e-18, Organism=Homo sapiens, GI157311622, Length=501, Percent_Identity=23.1536926147705, Blast_Score=92, Evalue=1e-18, Organism=Homo sapiens, GI27477105, Length=516, Percent_Identity=24.6124031007752, Blast_Score=87, Evalue=5e-17, Organism=Homo sapiens, GI57165412, Length=344, Percent_Identity=26.1627906976744, Blast_Score=86, Evalue=1e-16, Organism=Homo sapiens, GI57165410, Length=344, Percent_Identity=25.5813953488372, Blast_Score=83, Evalue=8e-16, Organism=Homo sapiens, GI40807491, Length=168, Percent_Identity=30.952380952381, Blast_Score=79, Evalue=9e-15, Organism=Homo sapiens, GI28416953, Length=523, Percent_Identity=24.8565965583174, Blast_Score=75, Evalue=1e-13, Organism=Homo sapiens, GI42794760, Length=138, Percent_Identity=31.1594202898551, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI42794758, Length=138, Percent_Identity=31.1594202898551, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI42794756, Length=138, Percent_Identity=31.1594202898551, Blast_Score=70, Evalue=4e-12, Organism=Escherichia coli, GI1788107, Length=521, Percent_Identity=30.5182341650672, Blast_Score=212, Evalue=4e-56, Organism=Escherichia coli, GI221142682, Length=490, Percent_Identity=31.0204081632653, Blast_Score=171, Evalue=8e-44, Organism=Escherichia coli, GI145693145, Length=537, Percent_Identity=29.4227188081937, Blast_Score=157, Evalue=2e-39, Organism=Escherichia coli, GI1786810, Length=489, Percent_Identity=25.7668711656442, Blast_Score=109, Evalue=4e-25, Organism=Escherichia coli, GI1788595, Length=345, Percent_Identity=27.536231884058, Blast_Score=95, Evalue=1e-20, Organism=Escherichia coli, GI1790505, Length=526, Percent_Identity=24.1444866920152, Blast_Score=77, Evalue=3e-15, Organism=Escherichia coli, GI1786801, Length=441, Percent_Identity=22.9024943310658, Blast_Score=73, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17559526, Length=525, Percent_Identity=29.1428571428571, Blast_Score=189, Evalue=4e-48, Organism=Caenorhabditis elegans, GI17560308, Length=521, Percent_Identity=26.4875239923225, Blast_Score=176, Evalue=2e-44, Organism=Caenorhabditis elegans, GI17531443, Length=509, Percent_Identity=25.3438113948919, Blast_Score=170, Evalue=2e-42, Organism=Caenorhabditis elegans, GI71994703, Length=529, Percent_Identity=27.2211720226843, Blast_Score=168, Evalue=5e-42, Organism=Caenorhabditis elegans, GI71994694, Length=529, Percent_Identity=27.2211720226843, Blast_Score=168, Evalue=6e-42, Organism=Caenorhabditis elegans, GI71994690, Length=529, Percent_Identity=27.2211720226843, Blast_Score=168, Evalue=6e-42, Organism=Caenorhabditis elegans, GI17538037, Length=364, Percent_Identity=28.5714285714286, Blast_Score=159, Evalue=3e-39, Organism=Caenorhabditis elegans, GI17557194, Length=364, Percent_Identity=28.2967032967033, Blast_Score=155, Evalue=5e-38, Organism=Caenorhabditis elegans, GI32563687, Length=483, Percent_Identity=28.1573498964803, Blast_Score=144, Evalue=9e-35, Organism=Caenorhabditis elegans, GI17558820, Length=484, Percent_Identity=27.4793388429752, Blast_Score=142, Evalue=4e-34, Organism=Caenorhabditis elegans, GI17560140, Length=448, Percent_Identity=26.5625, Blast_Score=135, Evalue=6e-32, Organism=Caenorhabditis elegans, GI71996755, Length=481, Percent_Identity=27.4428274428274, Blast_Score=131, Evalue=1e-30, Organism=Caenorhabditis elegans, GI71985884, Length=350, Percent_Identity=29.4285714285714, Blast_Score=120, Evalue=1e-27, Organism=Caenorhabditis elegans, GI25141359, Length=504, Percent_Identity=22.4206349206349, Blast_Score=90, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17564090, Length=484, Percent_Identity=20.8677685950413, Blast_Score=83, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17556552, Length=363, Percent_Identity=22.5895316804408, Blast_Score=71, Evalue=1e-12, Organism=Caenorhabditis elegans, GI25147511, Length=263, Percent_Identity=24.7148288973384, Blast_Score=71, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17510401, Length=182, Percent_Identity=30.2197802197802, Blast_Score=70, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6319699, Length=482, Percent_Identity=24.2738589211618, Blast_Score=139, Evalue=7e-34, Organism=Saccharomyces cerevisiae, GI6323182, Length=401, Percent_Identity=26.4339152119701, Blast_Score=89, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6320852, Length=341, Percent_Identity=25.2199413489736, Blast_Score=77, Evalue=6e-15, Organism=Saccharomyces cerevisiae, GI6324893, Length=171, Percent_Identity=28.0701754385965, Blast_Score=75, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6319264, Length=370, Percent_Identity=24.0540540540541, Blast_Score=66, Evalue=1e-11, Organism=Drosophila melanogaster, GI18859661, Length=368, Percent_Identity=33.4239130434783, Blast_Score=184, Evalue=1e-46, Organism=Drosophila melanogaster, GI21355181, Length=479, Percent_Identity=27.5574112734864, Blast_Score=169, Evalue=4e-42, Organism=Drosophila melanogaster, GI24581924, Length=513, Percent_Identity=28.8499025341131, Blast_Score=155, Evalue=5e-38, Organism=Drosophila melanogaster, GI24648260, Length=517, Percent_Identity=25.9187620889749, Blast_Score=144, Evalue=1e-34, Organism=Drosophila melanogaster, GI19922652, Length=526, Percent_Identity=28.3269961977186, Blast_Score=137, Evalue=2e-32, Organism=Drosophila melanogaster, GI281365686, Length=458, Percent_Identity=25.764192139738, Blast_Score=135, Evalue=5e-32, Organism=Drosophila melanogaster, GI21358303, Length=471, Percent_Identity=24.8407643312102, Blast_Score=133, Evalue=3e-31, Organism=Drosophila melanogaster, GI24653035, Length=480, Percent_Identity=26.25, Blast_Score=131, Evalue=1e-30, Organism=Drosophila melanogaster, GI21356947, Length=525, Percent_Identity=24.5714285714286, Blast_Score=128, Evalue=8e-30, Organism=Drosophila melanogaster, GI24648257, Length=493, Percent_Identity=23.9350912778905, Blast_Score=125, Evalue=5e-29, Organism=Drosophila melanogaster, GI161076582, Length=488, Percent_Identity=25.2049180327869, Blast_Score=120, Evalue=2e-27, Organism=Drosophila melanogaster, GI21356441, Length=450, Percent_Identity=24.4444444444444, Blast_Score=119, Evalue=4e-27, Organism=Drosophila melanogaster, GI20130357, Length=477, Percent_Identity=24.5283018867925, Blast_Score=114, Evalue=1e-25, Organism=Drosophila melanogaster, GI24648253, Length=506, Percent_Identity=23.9130434782609, Blast_Score=110, Evalue=2e-24, Organism=Drosophila melanogaster, GI24648255, Length=504, Percent_Identity=23.6111111111111, Blast_Score=107, Evalue=1e-23, Organism=Drosophila melanogaster, GI24656500, Length=493, Percent_Identity=23.9350912778905, Blast_Score=96, Evalue=4e-20, Organism=Drosophila melanogaster, GI221329755, Length=556, Percent_Identity=21.4028776978417, Blast_Score=86, Evalue=5e-17, Organism=Drosophila melanogaster, GI19921316, Length=544, Percent_Identity=24.0808823529412, Blast_Score=85, Evalue=1e-16, Organism=Drosophila melanogaster, GI281366413, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=7e-12, Organism=Drosophila melanogaster, GI24666501, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=8e-12, Organism=Drosophila melanogaster, GI24666497, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=8e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020459 - InterPro: IPR020845 - InterPro: IPR000873 [H]
Pfam domain/function: PF00501 AMP-binding [H]
EC number: =6.2.1.3 [H]
Molecular weight: Translated: 54352; Mature: 54221
Theoretical pI: Translated: 5.22; Mature: 5.22
Prosite motif: PS00455 AMP_BINDING
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTNSTRSPASLGRTLLAIAADRPAHPAVTTRSGSTSYRELADGALRVAAALTVQGLGLGD CCCCCCCHHHHCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCC RIAILARNDLPYVELIYGADFVGAVVVGINCRLSPAEVADILDDCQPSLVFVADEYLPLL EEEEEEECCCCEEEEEECCCHHEEEEEEECCCCCHHHHHHHHHCCCCCEEEEECHHHHHH GSAAAGVLRVSLDRDYRTWCGTGDMTRFVPRVGYADSVVLMVYTSGTTGRSKGVRLTEAN HHHCCCEEEEEECCCCHHHCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEEECC ITAALAANRDVWFVGPEIRALALFPLFNISGSIFLLSILHVGGEVVIAENASGATILELL EEEEEECCCCEEEECCCCEEEEEEHHHCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHH GARRITHALFVAAMIVALLDQPADDEIDLSSLRVLIYGAAPSSAAVIDRAMRRLPTCDFF HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCHH QGYGMTETCGGIAMTPPHRYGEEIAPASVGRAIPSYEIRIVDPVRRTDLPVGVEGEIWAR CCCCCCCCCCCEEECCCHHHCCCCCCHHHHCCCCCEEEEEECCHHHCCCCCCCCCCEEEC GPQNTIGYWNRAEETDRLLAADGWLRTGDVGVLDAAHNLYVVDRLKDMIISGGFNVYSLE CCCCCCCCCCCCCHHCCEEECCCCEEECCEEEEECCCCEEEHHHHHHHHHCCCCEEEEEE VEQILVGHPDVGDAAVFGVPDERWGETVVAVVTLRPGATCVPADLSEFARARLAHFKCPR EEEEEECCCCCCCEEEECCCCHHHCCEEEEEEEECCCCEECCCCHHHHHHHHHHHHCCCC RIEILDELPRNAAGKILKRELRGRFS HHHHHHHCCCHHHHHHHHHHHCCCCC >Mature Secondary Structure TNSTRSPASLGRTLLAIAADRPAHPAVTTRSGSTSYRELADGALRVAAALTVQGLGLGD CCCCCCHHHHCCEEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCC RIAILARNDLPYVELIYGADFVGAVVVGINCRLSPAEVADILDDCQPSLVFVADEYLPLL EEEEEEECCCCEEEEEECCCHHEEEEEEECCCCCHHHHHHHHHCCCCCEEEEECHHHHHH GSAAAGVLRVSLDRDYRTWCGTGDMTRFVPRVGYADSVVLMVYTSGTTGRSKGVRLTEAN HHHCCCEEEEEECCCCHHHCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEEECC ITAALAANRDVWFVGPEIRALALFPLFNISGSIFLLSILHVGGEVVIAENASGATILELL EEEEEECCCCEEEECCCCEEEEEEHHHCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHH GARRITHALFVAAMIVALLDQPADDEIDLSSLRVLIYGAAPSSAAVIDRAMRRLPTCDFF HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCHH QGYGMTETCGGIAMTPPHRYGEEIAPASVGRAIPSYEIRIVDPVRRTDLPVGVEGEIWAR CCCCCCCCCCCEEECCCHHHCCCCCCHHHHCCCCCEEEEEECCHHHCCCCCCCCCCEEEC GPQNTIGYWNRAEETDRLLAADGWLRTGDVGVLDAAHNLYVVDRLKDMIISGGFNVYSLE CCCCCCCCCCCCCHHCCEEECCCCEEECCEEEEECCCCEEEHHHHHHHHHCCCCEEEEEE VEQILVGHPDVGDAAVFGVPDERWGETVVAVVTLRPGATCVPADLSEFARARLAHFKCPR EEEEEECCCCCCCEEEECCCCHHHCCEEEEEEEECCCCEECCCCHHHHHHHHHHHHCCCC RIEILDELPRNAAGKILKRELRGRFS HHHHHHHCCCHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9579061; 9384377 [H]