BacMap

Definition	Frankia sp. EAN1pec chromosome, complete genome.
Accession	NC_009921
Length	8,982,042

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The map label for this gene is fabG [H]

Identifier: 158316109

GI number: 158316109

Start: 5169519

End: 5170412

Strand: Reverse

Name: fabG [H]

Synonym: Franean1_4327

Alternate gene names: 158316109

Gene position: 5170412-5169519 (Counterclockwise)

Preceding gene: 158316110

Following gene: 158316100

Centisome position: 57.56

GC content: 72.48

Gene sequence:

>894_bases
ATGGGTTGGTTCGAGGACAGAGGCGGGCTGGCGGGCAGCGTCGCCGTGGTCACCGGGGGAGCGGGGGGCATCGGCGGGGC
CGTGACCACCGACCTGGCGGCCAACGGCGTGCGCCTCGCGGTGGTCGACATCGACAAGGACGCGATCGACGCGCTGCAGG
CCGCGCTGGATGAGCAGGGCGCCGAGGCGATCGTGCACCACGGCGACGCCCGCGACCCCGACGTGCTCGCGGCGCTGTTC
GCCGCCGTCGACGAACGCTGGGGACGGGTCGACACCCTGGTCAACGTCGTCGGCGGCACCTTCCGCGCACCCTTCGTGGA
GACCAGCCCGAACGGCTGGAACGCACTGCTGCGCATGAACCTCATGCACGTGCTGCACGCCTGCTCGCTGGCCGCGCCCC
GGATGCAGGCGGGTGGGCGCGGCGGCAGCATCATCAACCTGACCACCATCGAGGCGCACCGGGCCGCCCCCGGGTTCGCG
GTCTACTCGGCGGCCAAGGCCGCGGTGGAGCAGTTCGGCCGGACCCTGGCCGTGGAGCTCGCCCCCGACCGGATCCGGGT
CAACAACGTCGCCCCCGACTACACCCCGACTCCCAACATGACCAAGATGACAGGCGGCGACGGCGCGTACTCGACCGAGG
TCGGGATCCGCGTCGGCATCCCGATGGGCCGGGCCGGCGAGGTCGCCGACGTGTCCGGCTGCGTGGTCTTCCTCGCTTCC
GGTCTCTCGACCTACGTCACCGGCTCGACCCTGCACCCCGACGGCGGCACCTACGCCTCGTCGGGATGGCTGAACTGGCC
GGGCACCGGTTTCTCGAACCACGCACCGTCGCACGTCCTGGCGAACCTGGGAGCGACCGGCGCCGACCCGTCGGCCGCAG
GGGAAGCCGGCTAG

Upstream 100 bases:

>100_bases
GCCGTGCCGAGTTCAGGTCGCGGGCGCGGTTGTGCCAGTCGGGTGGCGGGACCGGTCGTGACGTCGTGCCGGTCGTGACG
TGGAGTGGAGGCGCGGGTTC

Downstream 100 bases:

>100_bases
GAGCTGCACCTCTTCCTGAACTTCCTGAACCCCGCGGCCGCGCGGACGGTCTGGGGGTCTGGGGGTCAGTCAGTGGCACC
GGTGGGTGTTGAGTCGGGCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MGWFEDRGGLAGSVAVVTGGAGGIGGAVTTDLAANGVRLAVVDIDKDAIDALQAALDEQGAEAIVHHGDARDPDVLAALF
AAVDERWGRVDTLVNVVGGTFRAPFVETSPNGWNALLRMNLMHVLHACSLAAPRMQAGGRGGSIINLTTIEAHRAAPGFA
VYSAAKAAVEQFGRTLAVELAPDRIRVNNVAPDYTPTPNMTKMTGGDGAYSTEVGIRVGIPMGRAGEVADVSGCVVFLAS
GLSTYVTGSTLHPDGGTYASSGWLNWPGTGFSNHAPSHVLANLGATGADPSAAGEAG

Sequences:

>Translated_297_residues
MGWFEDRGGLAGSVAVVTGGAGGIGGAVTTDLAANGVRLAVVDIDKDAIDALQAALDEQGAEAIVHHGDARDPDVLAALF
AAVDERWGRVDTLVNVVGGTFRAPFVETSPNGWNALLRMNLMHVLHACSLAAPRMQAGGRGGSIINLTTIEAHRAAPGFA
VYSAAKAAVEQFGRTLAVELAPDRIRVNNVAPDYTPTPNMTKMTGGDGAYSTEVGIRVGIPMGRAGEVADVSGCVVFLAS
GLSTYVTGSTLHPDGGTYASSGWLNWPGTGFSNHAPSHVLANLGATGADPSAAGEAG
>Mature_296_residues
GWFEDRGGLAGSVAVVTGGAGGIGGAVTTDLAANGVRLAVVDIDKDAIDALQAALDEQGAEAIVHHGDARDPDVLAALFA
AVDERWGRVDTLVNVVGGTFRAPFVETSPNGWNALLRMNLMHVLHACSLAAPRMQAGGRGGSIINLTTIEAHRAAPGFAV
YSAAKAAVEQFGRTLAVELAPDRIRVNNVAPDYTPTPNMTKMTGGDGAYSTEVGIRVGIPMGRAGEVADVSGCVVFLASG
LSTYVTGSTLHPDGGTYASSGWLNWPGTGFSNHAPSHVLANLGATGADPSAAGEAG

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=35.9183673469388, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI19923817, Length=272, Percent_Identity=33.4558823529412, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=31.7647058823529, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=31.3953488372093, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=31.5175097276265, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=31.0756972111554, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI10190704, Length=265, Percent_Identity=30.188679245283, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=29.9610894941634, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI33667109, Length=203, Percent_Identity=33.4975369458128, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI31542939, Length=192, Percent_Identity=33.8541666666667, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=30.0518134715026, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4503301, Length=249, Percent_Identity=27.710843373494, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=34.7058823529412, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI59889578, Length=226, Percent_Identity=29.646017699115, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4758504, Length=206, Percent_Identity=31.0679611650485, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=30.6772908366534, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=32.8125, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=33.7301587301587, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=30.7086614173228, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=31.3253012048193, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=29.8039215686275, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=30.8300395256917, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=28.2868525896414, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=28.6885245901639, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=28.0155642023346, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=26.6932270916335, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=34.5381526104418, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=34.136546184739, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=28.6290322580645, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=26.5060240963855, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=273, Percent_Identity=27.8388278388278, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=28.3018867924528, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=26.9961977186312, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17561272, Length=255, Percent_Identity=30.1960784313725, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=275, Percent_Identity=28.7272727272727, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=29.5275590551181, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=265, Percent_Identity=28.6792452830189, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=29.2307692307692, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=26.1363636363636, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=273, Percent_Identity=27.1062271062271, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=26.3779527559055, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=26.5151515151515, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=275, Percent_Identity=27.6363636363636, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=27.1653543307087, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=24.6212121212121, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=26.1363636363636, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=25, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=275, Percent_Identity=26.9090909090909, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=25.6603773584906, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=24.4274809160305, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=24.5210727969349, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=272, Percent_Identity=23.8970588235294, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=27.1653543307087, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=30, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357041, Length=261, Percent_Identity=29.8850574712644, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=29.5275590551181, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571526, Length=265, Percent_Identity=30.5660377358491, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24643142, Length=261, Percent_Identity=30.6513409961686, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=31.6, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=27.5193798449612, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=30.078125, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24649181, Length=213, Percent_Identity=28.169014084507, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24665243, Length=204, Percent_Identity=27.9411764705882, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=28.9340101522843, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24665247, Length=205, Percent_Identity=27.8048780487805, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 30186; Mature: 30055

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWFEDRGGLAGSVAVVTGGAGGIGGAVTTDLAANGVRLAVVDIDKDAIDALQAALDEQG
CCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCC
AEAIVHHGDARDPDVLAALFAAVDERWGRVDTLVNVVGGTFRAPFVETSPNGWNALLRMN
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHH
LMHVLHACSLAAPRMQAGGRGGSIINLTTIEAHRAAPGFAVYSAAKAAVEQFGRTLAVEL
HHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHHHHHCCEEEEEE
APDRIRVNNVAPDYTPTPNMTKMTGGDGAYSTEVGIRVGIPMGRAGEVADVSGCVVFLAS
CCCEEEECCCCCCCCCCCCCEEECCCCCCEEECCCEEECCCCCCCCCCCHHHHHHHHHHC
GLSTYVTGSTLHPDGGTYASSGWLNWPGTGFSNHAPSHVLANLGATGADPSAAGEAG
CHHHHEECCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GWFEDRGGLAGSVAVVTGGAGGIGGAVTTDLAANGVRLAVVDIDKDAIDALQAALDEQG
CCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCC
AEAIVHHGDARDPDVLAALFAAVDERWGRVDTLVNVVGGTFRAPFVETSPNGWNALLRMN
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHH
LMHVLHACSLAAPRMQAGGRGGSIINLTTIEAHRAAPGFAVYSAAKAAVEQFGRTLAVEL
HHHHHHHHHHCCCHHHCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHHHHHCCEEEEEE
APDRIRVNNVAPDYTPTPNMTKMTGGDGAYSTEVGIRVGIPMGRAGEVADVSGCVVFLAS
CCCEEEECCCCCCCCCCCCCEEECCCCCCEEECCCEEECCCCCCCCCCCHHHHHHHHHHC
GLSTYVTGSTLHPDGGTYASSGWLNWPGTGFSNHAPSHVLANLGATGADPSAAGEAG
CHHHHEECCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]