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The map label for this gene is icd [H]

Identifier: 158316056

GI number: 158316056

Start: 5108256

End: 5110475

Strand: Reverse

Name: icd [H]

Synonym: Franean1_4274

Alternate gene names: 158316056

Gene position: 5110475-5108256 (Counterclockwise)

Preceding gene: 158316057

Following gene: 158316054

Centisome position: 56.9

GC content: 70.36

Gene sequence:

>2220_bases
GTGACTGATTCGGTGATCATCTACACCCAGACGGACGAGGCGCCGGCGCTGGCGACGTACTCGTTCCTGCCGGTGGTGCA
GGCGTACGCGTCGACGGCCGGGGTCGGCGTTGTCAGCCGCGACATTTCCCTGGCCGGGCGGATCATCGCCAGCTTCCCGG
AGCACCTCGAGCCGTCCCAGCGCATCGACGACGCGCTCGCCGAGCTCGGCGACCTGGCCCGCACGCCTGAGGCGAACATC
ATCAAGCTGCCGAACATCTCGGCGTCCATCCCGCAGCTGCGGGCCGCCGTCGTCGAGCTGCAGAAGCAGGGCTACGCGCT
GCCGGACTACCCCGACGACCCGAAGACCGACGAGGAGCGGGAGATCCGCGCCCGTTACGACAAGGTCAAGGGCAGCGCCG
TCAACCCCGTGCTGCGCGAGGGCAACTCCGACCGCCGCGCGCCGGCGTCGGTGAAGAGCTACGCCAAGGCCCACCCGCAC
CGCATGGGCGCCTGGAGCGTCGAGTCGAAGACGAACGTCGCCACCATGAGCGCCGACGACTTCCGTTCGACCGAGAAGTC
CGCGGTGATCGCCGCGGACGGCTCCCTGCGTATCGAGCTGGTCGGCGACGACGGCACCACGTCCGTCCTGCGCGAGTCGG
TACCGGTGCTCGCCAGCGAAGTCGTCGACGTCTCGGTCATGCGGGTCGGCGCGCTGCGCGAGTTCCTCACCGAGCAGGTG
GCCCGGGCGAAGGCCGAGGGCGTGCTGTTCTCGGTGCACCTGAAGGCCACGATGATGAAGGTCTCCGACCCGATCATCTT
CGGCCACGTCGTGCGTGCGTTCTTCCCCGAGACGTTCGCCCGCCACGGCGCGGCGCTCGCGGCGGCCGGCCTGACCCCGA
ACGAGGGCCTCGGCGGCATCTTCAAGGGGCTGGAGGCGCTGCCCGAGGGCGCCGAGATCAAGGCCTCCTTCGAGGCCGAG
CTCGCCGCCGGGCCGCCGCTGGCCATGGTCGACTCCGACCGGGGCATCACGAACCTGCACGTGCCCAGCGACGTCATCGT
CGACGCGTCCATGCCGGCGATGATCCGCACCTCCGGCCACATGTGGGGGCCGGACGGTGCCGAGGCGGACACCCTCGCCG
TCCTGCCCGACAGCAGCTACGCCGGCATCTACCAGGCCGTCATCGACGACTGCCGCGCGCACGGCGCCTACGACCCGGCG
ACGATGGGCTCGGTGCCCAACGTCGGCCTGATGGCGCAGAAGGCCGAGGAGTACGGCAGCCACGACAAGACCTTCGAGAT
CCCGACGACCGGCACCGTGCGGCTCGTCGACGGAGCGGGCACGGCGGTCCTCGAGCTGACCGTGAGCGCGGGTGACATCT
TCCGCGCCTGCCAGACCAAGGACGCCCCGATCCGCGACTGGGTGAAGCTCGCCGTCACCCGGGCCTGCGCCACCGGCAAC
CCGGCCGTGTTCTGGCTTGACGAGACCCGCGCGCACGACGCCCAGCTCATCACCAAGGTCCGGACCTACCTGGCCGACCA
CGACACCACCGGGCTGCAGATCGAGATCAAGGCCCCGGTCGACGCGATCACCTTCTCGCTGGAGCGGATCCGCCGCGGCG
AGGACACCATCTCGGTGACCGGCAACGTGCTGCGTGACTACCTGACCGACCTGTTCCCGATCCTGGAGCTCGGCACGAGC
GCAAAGATGCTCTCGGTCGTCCCGCTGATGAACGGCGGCGGCCTGTTCGAGACCGGTGCCGGCGGGTCGGCGCCCAAGCA
CGTCCAGCAGCTCGTCAAGGAGAACTACCTGCGCTGGGACAGCCTGGGTGAGTTCCTGGCGCTGGCGGTGAGCTTCGAGC
ACCTCGCGCAGCGCACCGGCAACGCCCGCGCCCAGGTGCTGGCCGACACCCTCGACCGGGCGACCGCGACCTTCCTCAAC
GAGGACAAGTCGCCCACCCGCCGGGTCGGCGGCATCGACAACCGGGGCAGCCACTTCTACCTGGCCCTGTACTGGGCCCA
GGAACTCGCGGCGCAGACCGACGACGCCGCGCTCGCGCAGGCGTTCACCAGCCTGGCCGAGAGCCTCGCGGCCCAGGAGA
AGACCATCGTCGACGAGCTGCTCGCCGTGCAGGGCTCGCCGGCCGACATCGGCGGCTACTACCAGCCCGACCCGGCCAAG
GCCGCGGCCGTGATGCGCCCGTCGAAGACCTTCAACGAGGCCATCGCGACGCTTGCCTGA

Upstream 100 bases:

>100_bases
ATGCACGGTGCCACATGCCTCTGCGTAATGATCAGTGGCGCGGGACGGGCAGGGCATACCTTGATACGACACGAAGTAGT
AGACGTGAAGCGGAGTATCG

Downstream 100 bases:

>100_bases
CCTGCCGGCCTGACCACGTGTCAGGAGCGGGACGTCAGGAGAACGTGGGTCAAGGGAAAGGGCCCGGGCTCCGCACGGGC
CCTTTCCCTGATCGTTCCGA

Product: isocitrate dehydrogenase, NADP-dependent

Products: NA

Alternate protein names: IDH; Oxalosuccinate decarboxylase [H]

Number of amino acids: Translated: 739; Mature: 738

Protein sequence:

>739_residues
MTDSVIIYTQTDEAPALATYSFLPVVQAYASTAGVGVVSRDISLAGRIIASFPEHLEPSQRIDDALAELGDLARTPEANI
IKLPNISASIPQLRAAVVELQKQGYALPDYPDDPKTDEEREIRARYDKVKGSAVNPVLREGNSDRRAPASVKSYAKAHPH
RMGAWSVESKTNVATMSADDFRSTEKSAVIAADGSLRIELVGDDGTTSVLRESVPVLASEVVDVSVMRVGALREFLTEQV
ARAKAEGVLFSVHLKATMMKVSDPIIFGHVVRAFFPETFARHGAALAAAGLTPNEGLGGIFKGLEALPEGAEIKASFEAE
LAAGPPLAMVDSDRGITNLHVPSDVIVDASMPAMIRTSGHMWGPDGAEADTLAVLPDSSYAGIYQAVIDDCRAHGAYDPA
TMGSVPNVGLMAQKAEEYGSHDKTFEIPTTGTVRLVDGAGTAVLELTVSAGDIFRACQTKDAPIRDWVKLAVTRACATGN
PAVFWLDETRAHDAQLITKVRTYLADHDTTGLQIEIKAPVDAITFSLERIRRGEDTISVTGNVLRDYLTDLFPILELGTS
AKMLSVVPLMNGGGLFETGAGGSAPKHVQQLVKENYLRWDSLGEFLALAVSFEHLAQRTGNARAQVLADTLDRATATFLN
EDKSPTRRVGGIDNRGSHFYLALYWAQELAAQTDDAALAQAFTSLAESLAAQEKTIVDELLAVQGSPADIGGYYQPDPAK
AAAVMRPSKTFNEAIATLA

Sequences:

>Translated_739_residues
MTDSVIIYTQTDEAPALATYSFLPVVQAYASTAGVGVVSRDISLAGRIIASFPEHLEPSQRIDDALAELGDLARTPEANI
IKLPNISASIPQLRAAVVELQKQGYALPDYPDDPKTDEEREIRARYDKVKGSAVNPVLREGNSDRRAPASVKSYAKAHPH
RMGAWSVESKTNVATMSADDFRSTEKSAVIAADGSLRIELVGDDGTTSVLRESVPVLASEVVDVSVMRVGALREFLTEQV
ARAKAEGVLFSVHLKATMMKVSDPIIFGHVVRAFFPETFARHGAALAAAGLTPNEGLGGIFKGLEALPEGAEIKASFEAE
LAAGPPLAMVDSDRGITNLHVPSDVIVDASMPAMIRTSGHMWGPDGAEADTLAVLPDSSYAGIYQAVIDDCRAHGAYDPA
TMGSVPNVGLMAQKAEEYGSHDKTFEIPTTGTVRLVDGAGTAVLELTVSAGDIFRACQTKDAPIRDWVKLAVTRACATGN
PAVFWLDETRAHDAQLITKVRTYLADHDTTGLQIEIKAPVDAITFSLERIRRGEDTISVTGNVLRDYLTDLFPILELGTS
AKMLSVVPLMNGGGLFETGAGGSAPKHVQQLVKENYLRWDSLGEFLALAVSFEHLAQRTGNARAQVLADTLDRATATFLN
EDKSPTRRVGGIDNRGSHFYLALYWAQELAAQTDDAALAQAFTSLAESLAAQEKTIVDELLAVQGSPADIGGYYQPDPAK
AAAVMRPSKTFNEAIATLA
>Mature_738_residues
TDSVIIYTQTDEAPALATYSFLPVVQAYASTAGVGVVSRDISLAGRIIASFPEHLEPSQRIDDALAELGDLARTPEANII
KLPNISASIPQLRAAVVELQKQGYALPDYPDDPKTDEEREIRARYDKVKGSAVNPVLREGNSDRRAPASVKSYAKAHPHR
MGAWSVESKTNVATMSADDFRSTEKSAVIAADGSLRIELVGDDGTTSVLRESVPVLASEVVDVSVMRVGALREFLTEQVA
RAKAEGVLFSVHLKATMMKVSDPIIFGHVVRAFFPETFARHGAALAAAGLTPNEGLGGIFKGLEALPEGAEIKASFEAEL
AAGPPLAMVDSDRGITNLHVPSDVIVDASMPAMIRTSGHMWGPDGAEADTLAVLPDSSYAGIYQAVIDDCRAHGAYDPAT
MGSVPNVGLMAQKAEEYGSHDKTFEIPTTGTVRLVDGAGTAVLELTVSAGDIFRACQTKDAPIRDWVKLAVTRACATGNP
AVFWLDETRAHDAQLITKVRTYLADHDTTGLQIEIKAPVDAITFSLERIRRGEDTISVTGNVLRDYLTDLFPILELGTSA
KMLSVVPLMNGGGLFETGAGGSAPKHVQQLVKENYLRWDSLGEFLALAVSFEHLAQRTGNARAQVLADTLDRATATFLNE
DKSPTRRVGGIDNRGSHFYLALYWAQELAAQTDDAALAQAFTSLAESLAAQEKTIVDELLAVQGSPADIGGYYQPDPAKA
AAVMRPSKTFNEAIATLA

Specific function: Unknown

COG id: COG2838

COG function: function code C; Monomeric isocitrate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monomeric-type IDH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001804
- InterPro:   IPR004436 [H]

Pfam domain/function: PF03971 IDH [H]

EC number: =1.1.1.42 [H]

Molecular weight: Translated: 78957; Mature: 78826

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSVIIYTQTDEAPALATYSFLPVVQAYASTAGVGVVSRDISLAGRIIASFPEHLEPSQ
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCHHHCCHHH
RIDDALAELGDLARTPEANIIKLPNISASIPQLRAAVVELQKQGYALPDYPDDPKTDEER
HHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
EIRARYDKVKGSAVNPVLREGNSDRRAPASVKSYAKAHPHRMGAWSVESKTNVATMSADD
HHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCEEEECCHH
FRSTEKSAVIAADGSLRIELVGDDGTTSVLRESVPVLASEVVDVSVMRVGALREFLTEQV
HCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAKAEGVLFSVHLKATMMKVSDPIIFGHVVRAFFPETFARHGAALAAAGLTPNEGLGGI
HHHHHCCEEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHH
FKGLEALPEGAEIKASFEAELAAGPPLAMVDSDRGITNLHVPSDVIVDASMPAMIRTSGH
HHHHHHCCCCCEEEEECCEEECCCCCEEEEECCCCCEEEECCCCEEECCCCCCCEECCCC
MWGPDGAEADTLAVLPDSSYAGIYQAVIDDCRAHGAYDPATMGSVPNVGLMAQKAEEYGS
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHCC
HDKTFEIPTTGTVRLVDGAGTAVLELTVSAGDIFRACQTKDAPIRDWVKLAVTRACATGN
CCCEEECCCCCEEEEEECCCCEEEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
PAVFWLDETRAHDAQLITKVRTYLADHDTTGLQIEIKAPVDAITFSLERIRRGEDTISVT
CEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEC
GNVLRDYLTDLFPILELGTSAKMLSVVPLMNGGGLFETGAGGSAPKHVQQLVKENYLRWD
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEECCCCCCCHHHHHHHHHHHCCCHH
SLGEFLALAVSFEHLAQRTGNARAQVLADTLDRATATFLNEDKSPTRRVGGIDNRGSHFY
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEE
LALYWAQELAAQTDDAALAQAFTSLAESLAAQEKTIVDELLAVQGSPADIGGYYQPDPAK
EEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
AAAVMRPSKTFNEAIATLA
HHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TDSVIIYTQTDEAPALATYSFLPVVQAYASTAGVGVVSRDISLAGRIIASFPEHLEPSQ
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCHHHCCHHH
RIDDALAELGDLARTPEANIIKLPNISASIPQLRAAVVELQKQGYALPDYPDDPKTDEER
HHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
EIRARYDKVKGSAVNPVLREGNSDRRAPASVKSYAKAHPHRMGAWSVESKTNVATMSADD
HHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCEEEECCHH
FRSTEKSAVIAADGSLRIELVGDDGTTSVLRESVPVLASEVVDVSVMRVGALREFLTEQV
HCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARAKAEGVLFSVHLKATMMKVSDPIIFGHVVRAFFPETFARHGAALAAAGLTPNEGLGGI
HHHHHCCEEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHH
FKGLEALPEGAEIKASFEAELAAGPPLAMVDSDRGITNLHVPSDVIVDASMPAMIRTSGH
HHHHHHCCCCCEEEEECCEEECCCCCEEEEECCCCCEEEECCCCEEECCCCCCCEECCCC
MWGPDGAEADTLAVLPDSSYAGIYQAVIDDCRAHGAYDPATMGSVPNVGLMAQKAEEYGS
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHCC
HDKTFEIPTTGTVRLVDGAGTAVLELTVSAGDIFRACQTKDAPIRDWVKLAVTRACATGN
CCCEEECCCCCEEEEEECCCCEEEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
PAVFWLDETRAHDAQLITKVRTYLADHDTTGLQIEIKAPVDAITFSLERIRRGEDTISVT
CEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEC
GNVLRDYLTDLFPILELGTSAKMLSVVPLMNGGGLFETGAGGSAPKHVQQLVKENYLRWD
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEECCCCCCCHHHHHHHHHHHCCCHH
SLGEFLALAVSFEHLAQRTGNARAQVLADTLDRATATFLNEDKSPTRRVGGIDNRGSHFY
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEE
LALYWAQELAAQTDDAALAQAFTSLAESLAAQEKTIVDELLAVQGSPADIGGYYQPDPAK
EEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
AAAVMRPSKTFNEAIATLA
HHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12005040; 4149369; 12467571 [H]