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The map label for this gene is adh [H]

Identifier: 158316009

GI number: 158316009

Start: 5034115

End: 5035149

Strand: Reverse

Name: adh [H]

Synonym: Franean1_4227

Alternate gene names: 158316009

Gene position: 5035149-5034115 (Counterclockwise)

Preceding gene: 158316010

Following gene: 158316008

Centisome position: 56.06

GC content: 70.92

Gene sequence:

>1035_bases
GTGAGCCGTGCCATCGTCTTCAACGGCGACGAGACCTGGGAGGAACGCGACCTCCCCGTCCCCGACCCCCAGCCCGGCGG
CGCCGTCCTGCGCGTCGAGGCCACCGGCCTGTGCCACAGCGACATCGACCACTTCCGCGGCCACGTCCACACCTCCTGGG
GCGGTGCCTTCCCCTCCATCGCCGGCCACGAGATCGTCGGCCGCGTCGAGAAGATCGATTCGGCCACGGCCGAGGCGTGG
GGGGTGGCGGAAGGCGACCGGGTCGCCGTCCGTGAGCTCCTCGTCACGCCCGAGGGGTACCGGATCTACGGCCACGACTT
CTCGGTGGACGAGGGCTCGGGCCTGTACGGCGGCTTCGCCGAACACCTCGAACTGCTGCCCGGCTCCCAGGTCTACCGCC
TGCGCGAGGACCTCCCCGCCGACCAGCTCACGGTCTTCGAACCGCTGAGCTGCGCGGTCACCTGGGTGGCGCCGGTCAGG
AAGGGCGACGTCGTCGTCATCGAGGGGCCAGGCCACATGGGGATGGCGACCATCGTCGCCGCCCGTGCGGCCGGCGCCTC
GACCATCATCGTCACCGGCACGGCCAGGGACCGCTTCCGCCTCGACTGGGCACTGCGCGTCGGCGCCGACCACACCGTCG
ACGTCGACTCCGAGGACCCCCTCGAACGGGTCCGCGAGCTCACCGACGGCCGCCTGGCCGACGTCGTCATCGACGCCGCC
GCCGGTAATCCGGTCACCATCAACCTCGCTATGGACCTCGTCCGCAAGGGTGGGCACGTCGTCATCGCCGGGATGAAGGA
CCGCCCCCTCGAAGGCTTCCACAGCGACTGGATCCCCACCCGACGGATCACCCTGCACCCCGGCGCCGGCCTCGACACCG
AGGCGGCCGTCGACCTCATCAACGCGGGCAAGGTACCGACCGGCGAGCTGCTCGGCGACACCTTCCCCCTCGAACATTTC
GAGGATGCCTTCGCGCTTCTGACCCGCAGGACACCCGGCCGAGACTCGATCCGGATCGCCCTGCGCCTCACCTAG

Upstream 100 bases:

>100_bases
AACTCGAACTCGTCGGCCCCGCCATCGAGGCCGAAGGGCACATCAGCGCCACCCGGCGCGCGGTGGAACGCGCGAGCGGG
CTGCTCGAGGAGGTCCTGAC

Downstream 100 bases:

>100_bases
TCTCCCACCGCGGTATCCGGGGGTGCGTCCCTTGATGGAAAGAAGTCCATTCATGAGAACTCCACTGATGCCGAGGATGA
CGCATCTGCAGCGGCTGGAG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSRAIVFNGDETWEERDLPVPDPQPGGAVLRVEATGLCHSDIDHFRGHVHTSWGGAFPSIAGHEIVGRVEKIDSATAEAW
GVAEGDRVAVRELLVTPEGYRIYGHDFSVDEGSGLYGGFAEHLELLPGSQVYRLREDLPADQLTVFEPLSCAVTWVAPVR
KGDVVVIEGPGHMGMATIVAARAAGASTIIVTGTARDRFRLDWALRVGADHTVDVDSEDPLERVRELTDGRLADVVIDAA
AGNPVTINLAMDLVRKGGHVVIAGMKDRPLEGFHSDWIPTRRITLHPGAGLDTEAAVDLINAGKVPTGELLGDTFPLEHF
EDAFALLTRRTPGRDSIRIALRLT

Sequences:

>Translated_344_residues
MSRAIVFNGDETWEERDLPVPDPQPGGAVLRVEATGLCHSDIDHFRGHVHTSWGGAFPSIAGHEIVGRVEKIDSATAEAW
GVAEGDRVAVRELLVTPEGYRIYGHDFSVDEGSGLYGGFAEHLELLPGSQVYRLREDLPADQLTVFEPLSCAVTWVAPVR
KGDVVVIEGPGHMGMATIVAARAAGASTIIVTGTARDRFRLDWALRVGADHTVDVDSEDPLERVRELTDGRLADVVIDAA
AGNPVTINLAMDLVRKGGHVVIAGMKDRPLEGFHSDWIPTRRITLHPGAGLDTEAAVDLINAGKVPTGELLGDTFPLEHF
EDAFALLTRRTPGRDSIRIALRLT
>Mature_343_residues
SRAIVFNGDETWEERDLPVPDPQPGGAVLRVEATGLCHSDIDHFRGHVHTSWGGAFPSIAGHEIVGRVEKIDSATAEAWG
VAEGDRVAVRELLVTPEGYRIYGHDFSVDEGSGLYGGFAEHLELLPGSQVYRLREDLPADQLTVFEPLSCAVTWVAPVRK
GDVVVIEGPGHMGMATIVAARAAGASTIIVTGTARDRFRLDWALRVGADHTVDVDSEDPLERVRELTDGRLADVVIDAAA
GNPVTINLAMDLVRKGGHVVIAGMKDRPLEGFHSDWIPTRRITLHPGAGLDTEAAVDLINAGKVPTGELLGDTFPLEHFE
DAFALLTRRTPGRDSIRIALRLT

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788075, Length=344, Percent_Identity=23.2558139534884, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788073, Length=258, Percent_Identity=27.1317829457364, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787863, Length=328, Percent_Identity=23.780487804878, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790045, Length=267, Percent_Identity=24.3445692883895, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI226510992, Length=272, Percent_Identity=28.3088235294118, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562584, Length=354, Percent_Identity=25.7062146892655, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562878, Length=341, Percent_Identity=25.5131964809384, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322619, Length=339, Percent_Identity=28.6135693215339, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6319955, Length=339, Percent_Identity=28.6135693215339, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319257, Length=299, Percent_Identity=26.0869565217391, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17737897, Length=351, Percent_Identity=27.6353276353276, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 37130; Mature: 36999

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAIVFNGDETWEERDLPVPDPQPGGAVLRVEATGLCHSDIDHFRGHVHTSWGGAFPSI
CCCEEEECCCCCHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCEEEECCCCCCCCC
AGHEIVGRVEKIDSATAEAWGVAEGDRVAVRELLVTPEGYRIYGHDFSVDEGSGLYGGFA
CCHHHHHHHHHHCCHHHHHCCCCCCCHHEEHHHHCCCCCCEEECCEECCCCCCCCCCCHH
EHLELLPGSQVYRLREDLPADQLTVFEPLSCAVTWVAPVRKGDVVVIEGPGHMGMATIVA
HHHHHCCCHHHHHHHHHCCCCCEEEECCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHH
ARAAGASTIIVTGTARDRFRLDWALRVGADHTVDVDSEDPLERVRELTDGRLADVVIDAA
HHCCCCEEEEEECCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHCCCCEEEEEEECC
AGNPVTINLAMDLVRKGGHVVIAGMKDRPLEGFHSDWIPTRRITLHPGAGLDTEAAVDLI
CCCCEEEEEEHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHH
NAGKVPTGELLGDTFPLEHFEDAFALLTRRTPGRDSIRIALRLT
HCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
SRAIVFNGDETWEERDLPVPDPQPGGAVLRVEATGLCHSDIDHFRGHVHTSWGGAFPSI
CCEEEECCCCCHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCEEEECCCCCCCCC
AGHEIVGRVEKIDSATAEAWGVAEGDRVAVRELLVTPEGYRIYGHDFSVDEGSGLYGGFA
CCHHHHHHHHHHCCHHHHHCCCCCCCHHEEHHHHCCCCCCEEECCEECCCCCCCCCCCHH
EHLELLPGSQVYRLREDLPADQLTVFEPLSCAVTWVAPVRKGDVVVIEGPGHMGMATIVA
HHHHHCCCHHHHHHHHHCCCCCEEEECCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHH
ARAAGASTIIVTGTARDRFRLDWALRVGADHTVDVDSEDPLERVRELTDGRLADVVIDAA
HHCCCCEEEEEECCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHCCCCEEEEEEECC
AGNPVTINLAMDLVRKGGHVVIAGMKDRPLEGFHSDWIPTRRITLHPGAGLDTEAAVDLI
CCCCEEEEEEHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHH
NAGKVPTGELLGDTFPLEHFEDAFALLTRRTPGRDSIRIALRLT
HCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]