Click here to switch to the map view.

The map label for this gene is fabA [H]

Identifier: 158315741

GI number: 158315741

Start: 4726650

End: 4728977

Strand: Reverse

Name: fabA [H]

Synonym: Franean1_3953

Alternate gene names: 158315741

Gene position: 4728977-4726650 (Counterclockwise)

Preceding gene: 158315742

Following gene: 158315740

Centisome position: 52.65

GC content: 76.59

Gene sequence:

>2328_bases
ATGACAGTCGAGATGACCGGACCGGCACTCGTGACACCGTTCGTCGTGGAGGACGACGAGCTGTCGTTCGACGGGGAGCC
CTTCGACAGCCTGCGACTGACCGCCACGGGGCCGACAGCCGCGGCGCCGCCCACGCCAGCACCCCCCACGGCCCCGCAAC
CCGCCGCGGCGGCGGCCGGCCCCGCACCGCGGATCGCGGATGTCGTCCGCGAGGTGCGCGCGGTCGTGGTGGCCGCCCAC
GAGTCGGCGCTGAACGCGCAGCTCGCGCTCACCCGGCTCACTCTCGCGGGTCCCGGCCGGCCATTGGCAGCCGGCTCGCA
GGCGCTCGTCCTTCCGCCGGCCGCCGCGGCCTCGGGCGTTCCCGCCCCGGCCGTGCTCACCGCCGGGGTACCCGCCGCGC
CGGCCGGGCTCACGGCACCGGCCGGTCCCGCTGTGGCGGCCGGGCGGGTTGCTCCGGACGTCGCGCCGACGGATCCGGTC
GCGACGGAGGCGGCGTTCAAGCCGCTCGCCCGCTCCGGGCGCCGGGAGCTCACCGACGCCGACCTGGCCGCGCTGGTCCG
CGGCGAGGTGGCCGGCGTCTTCGGCCCGGCCTACGACCAGGAGGGCGTCAACCCGGACGTTCGGCTCACCGACCCCGGCG
AGGCGACCCTGCTCACCTGGGTGGCGGACCTGCGGCTGCGCGGCGGGAGCCGCACCGCGGGCTCGCTGCACGCCGGGCTG
CGTGCGCTGCCCGGCACGGCCGCGCCCGGCTCGTTCGCCGGAGCGGCCGGGTCCGGTTCGCTGGCCGACGCGCTCCAGGC
GGCGGCCGCGCAGGCCGCCAAGGTGTTCGCCCTCTACGCCGGCCTGCACCTGTGCCTTGCGGACGCCCGGTTCGTCGCCG
GCCCGCCGGCCGAGGACGCCGACGGCGGCCCGCGCACCGGCGCGCGGCCGCCCGCCCCGACAGTGGCCCTCACCGCCGAC
GGCGGGGGCTGGGACGGCACCGGCGGCGAGCTCGTCCTCGACGTCACCGCCATCGACCTGATCCCGCGGCCCTGGCTCGC
CGTGCGCGCGCTGGTCCACGCGGGCGGCCGGCTGGTCGCCGAGGTCCGCGACGTCGCGGTCACCGTGCGGGAGCGGCCGG
GCGCGCCGGTCGGCGCCGACCATGGCGGGGCCGTCACCGCGTTCCTGGGCCGGCGCACCGCGGCCGGCGAGCGGGCGCTG
CTCAGCGAGTTCCACATGGCCCACTGCGCACGCGGCGACCAGGGCGTCGGCCTCGGGCCCGAGTTCGCCGCCTACCGGGG
GCGGCGTGCGACCCGGCTGCCCGGCGGCGGCCTGCGCCTCGTCGACCGGGTGATGGCGATGGACTCGCGGCGCGGTGACC
TGCGCGGCGGGGCGACGCACGTCACCGAGTACGACGCGGCGGCCGACTGCTGGTACTTCACCGAGACGGCGAACGCGTCC
ATGCCGAACTGCGTCTACATGGAGACCAGCCTGCAGGCCGCGCTGATGCTGGGCTACTACCTCGGCGCCACGCTGGCCCA
GCCGGCGGAGGACTACAGCCTGCGCAACCTCGGCGGCAGCGCGACCGTGCTGCGGGAGGTCGACCTGCGCGACGCCACGA
TCCGCCAGCACTCGACGCTGCTGTCGACCAACCCGATGCCCGGCACGGCGCTGCAGGACTTCTCCTACGAGCTCGCCGTC
GACGGCGAGCCGTTCTACACCGGCGAGTCGATGTTCGGGTACTTCAACGCCCCGGCGCTGGCCCGCCAGACCGGCCTGGA
CGGCGGCCGCCTCGAGCCGACCTGGCTGGACGCGCTCGACGAACGGGAGCGCCCGCCGGTCCGGATGATCGACGTGGCCG
CCCGCCGTGCCGACCCGGCCGCACCGCTGTGCGCCCGCGGCCACCTGGCGCTGCTCGACGACGTCGAGGTGGTGGACGGC
GGCGGCCGGTTCGGGCAGGGCTACCTGCGCGCCGTGCGGCCGATCGACCCGGCGGACTGGTTCTTCGCCCGGCACTTCTA
CCTCGACCCGGTCATCCCCGGCTCGCTCGGGGTGGAGGCGGTCATCCAGGCCATGCAGGAGTGGGTCATCGACGCCGGCC
ATCTCGCCGGCCTCGCCCGGCCCGGGTTCGTGCTGCCCGTGGGCGTGCCCCTGCAGTGGAAGTACCGCGGCCAGCTCCTG
CCCTCCGACGGGACGTTCACCCTGGAGGTCCACATCAAGGACGTCAGCCACCGGCCCGGCCGGGTCCGCGTCACCGCCGA
CGCGAGCCTGTGGAAGCCGACGATGCGCATCTACGAGCTGATCGACGTGGCCGTGGAGCTGCGTGACGAGGGCGCGCCGT
CGTGGTGA

Upstream 100 bases:

>100_bases
TCCTCGTCCGCCTGCACGACGTGGCGATGGTCGGGACGCCCGACATGGCCGCGAAGTTCGCCGAGGGCACCGCGAGCTGG
CACAAGAAGGAGGTGTCCGC

Downstream 100 bases:

>100_bases
CCCCGGTCGCGCCCGCCCCCCGCCCCGCGGCGGCTCAGCCGGCCACGGCCCACCCCGGCGCGGCCGGGGCACTCGCCCGG
CGGCCGGCCGACATCCACCG

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 775; Mature: 774

Protein sequence:

>775_residues
MTVEMTGPALVTPFVVEDDELSFDGEPFDSLRLTATGPTAAAPPTPAPPTAPQPAAAAAGPAPRIADVVREVRAVVVAAH
ESALNAQLALTRLTLAGPGRPLAAGSQALVLPPAAAASGVPAPAVLTAGVPAAPAGLTAPAGPAVAAGRVAPDVAPTDPV
ATEAAFKPLARSGRRELTDADLAALVRGEVAGVFGPAYDQEGVNPDVRLTDPGEATLLTWVADLRLRGGSRTAGSLHAGL
RALPGTAAPGSFAGAAGSGSLADALQAAAAQAAKVFALYAGLHLCLADARFVAGPPAEDADGGPRTGARPPAPTVALTAD
GGGWDGTGGELVLDVTAIDLIPRPWLAVRALVHAGGRLVAEVRDVAVTVRERPGAPVGADHGGAVTAFLGRRTAAGERAL
LSEFHMAHCARGDQGVGLGPEFAAYRGRRATRLPGGGLRLVDRVMAMDSRRGDLRGGATHVTEYDAAADCWYFTETANAS
MPNCVYMETSLQAALMLGYYLGATLAQPAEDYSLRNLGGSATVLREVDLRDATIRQHSTLLSTNPMPGTALQDFSYELAV
DGEPFYTGESMFGYFNAPALARQTGLDGGRLEPTWLDALDERERPPVRMIDVAARRADPAAPLCARGHLALLDDVEVVDG
GGRFGQGYLRAVRPIDPADWFFARHFYLDPVIPGSLGVEAVIQAMQEWVIDAGHLAGLARPGFVLPVGVPLQWKYRGQLL
PSDGTFTLEVHIKDVSHRPGRVRVTADASLWKPTMRIYELIDVAVELRDEGAPSW

Sequences:

>Translated_775_residues
MTVEMTGPALVTPFVVEDDELSFDGEPFDSLRLTATGPTAAAPPTPAPPTAPQPAAAAAGPAPRIADVVREVRAVVVAAH
ESALNAQLALTRLTLAGPGRPLAAGSQALVLPPAAAASGVPAPAVLTAGVPAAPAGLTAPAGPAVAAGRVAPDVAPTDPV
ATEAAFKPLARSGRRELTDADLAALVRGEVAGVFGPAYDQEGVNPDVRLTDPGEATLLTWVADLRLRGGSRTAGSLHAGL
RALPGTAAPGSFAGAAGSGSLADALQAAAAQAAKVFALYAGLHLCLADARFVAGPPAEDADGGPRTGARPPAPTVALTAD
GGGWDGTGGELVLDVTAIDLIPRPWLAVRALVHAGGRLVAEVRDVAVTVRERPGAPVGADHGGAVTAFLGRRTAAGERAL
LSEFHMAHCARGDQGVGLGPEFAAYRGRRATRLPGGGLRLVDRVMAMDSRRGDLRGGATHVTEYDAAADCWYFTETANAS
MPNCVYMETSLQAALMLGYYLGATLAQPAEDYSLRNLGGSATVLREVDLRDATIRQHSTLLSTNPMPGTALQDFSYELAV
DGEPFYTGESMFGYFNAPALARQTGLDGGRLEPTWLDALDERERPPVRMIDVAARRADPAAPLCARGHLALLDDVEVVDG
GGRFGQGYLRAVRPIDPADWFFARHFYLDPVIPGSLGVEAVIQAMQEWVIDAGHLAGLARPGFVLPVGVPLQWKYRGQLL
PSDGTFTLEVHIKDVSHRPGRVRVTADASLWKPTMRIYELIDVAVELRDEGAPSW
>Mature_774_residues
TVEMTGPALVTPFVVEDDELSFDGEPFDSLRLTATGPTAAAPPTPAPPTAPQPAAAAAGPAPRIADVVREVRAVVVAAHE
SALNAQLALTRLTLAGPGRPLAAGSQALVLPPAAAASGVPAPAVLTAGVPAAPAGLTAPAGPAVAAGRVAPDVAPTDPVA
TEAAFKPLARSGRRELTDADLAALVRGEVAGVFGPAYDQEGVNPDVRLTDPGEATLLTWVADLRLRGGSRTAGSLHAGLR
ALPGTAAPGSFAGAAGSGSLADALQAAAAQAAKVFALYAGLHLCLADARFVAGPPAEDADGGPRTGARPPAPTVALTADG
GGWDGTGGELVLDVTAIDLIPRPWLAVRALVHAGGRLVAEVRDVAVTVRERPGAPVGADHGGAVTAFLGRRTAAGERALL
SEFHMAHCARGDQGVGLGPEFAAYRGRRATRLPGGGLRLVDRVMAMDSRRGDLRGGATHVTEYDAAADCWYFTETANASM
PNCVYMETSLQAALMLGYYLGATLAQPAEDYSLRNLGGSATVLREVDLRDATIRQHSTLLSTNPMPGTALQDFSYELAVD
GEPFYTGESMFGYFNAPALARQTGLDGGRLEPTWLDALDERERPPVRMIDVAARRADPAAPLCARGHLALLDDVEVVDGG
GRFGQGYLRAVRPIDPADWFFARHFYLDPVIPGSLGVEAVIQAMQEWVIDAGHLAGLARPGFVLPVGVPLQWKYRGQLLP
SDGTFTLEVHIKDVSHRPGRVRVTADASLWKPTMRIYELIDVAVELRDEGAPSW

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=104, Percent_Identity=37.5, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 80499; Mature: 80368

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEMTGPALVTPFVVEDDELSFDGEPFDSLRLTATGPTAAAPPTPAPPTAPQPAAAAAG
CEEEECCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
PAPRIADVVREVRAVVVAAHESALNAQLALTRLTLAGPGRPLAAGSQALVLPPAAAASGV
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCEEEECCHHHCCCC
PAPAVLTAGVPAAPAGLTAPAGPAVAAGRVAPDVAPTDPVATEAAFKPLARSGRRELTDA
CCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHH
DLAALVRGEVAGVFGPAYDQEGVNPDVRLTDPGEATLLTWVADLRLRGGSRTAGSLHAGL
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHEEEEHHHCCCCCCCCHHHHHHH
RALPGTAAPGSFAGAAGSGSLADALQAAAAQAAKVFALYAGLHLCLADARFVAGPPAEDA
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCC
DGGPRTGARPPAPTVALTADGGGWDGTGGELVLDVTAIDLIPRPWLAVRALVHAGGRLVA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCHHHH
EVRDVAVTVRERPGAPVGADHGGAVTAFLGRRTAAGERALLSEFHMAHCARGDQGVGLGP
HHHHHEEEEECCCCCCCCCCCCCEEEHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
EFAAYRGRRATRLPGGGLRLVDRVMAMDSRRGDLRGGATHVTEYDAAADCWYFTETANAS
HHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEEEEECCCCC
MPNCVYMETSLQAALMLGYYLGATLAQPAEDYSLRNLGGSATVLREVDLRDATIRQHSTL
CCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEECCCCHHHHHHHHHH
LSTNPMPGTALQDFSYELAVDGEPFYTGESMFGYFNAPALARQTGLDGGRLEPTWLDALD
EECCCCCCCHHHCCCEEEEECCCCCCCCCCCCEECCCCHHHHHCCCCCCCCCHHHHHHHH
ERERPPVRMIDVAARRADPAAPLCARGHLALLDDVEVVDGGGRFGQGYLRAVRPIDPADW
HCCCCCCHHHHHHHHCCCCCCCHHCCCCEEEECCEEEECCCCCCCCHHHHHCCCCCCHHH
FFARHFYLDPVIPGSLGVEAVIQAMQEWVIDAGHLAGLARPGFVLPVGVPLQWKYRGQLL
HHHHHEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCEEEEECCCEEEEECCEEC
PSDGTFTLEVHIKDVSHRPGRVRVTADASLWKPTMRIYELIDVAVELRDEGAPSW
CCCCEEEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVEMTGPALVTPFVVEDDELSFDGEPFDSLRLTATGPTAAAPPTPAPPTAPQPAAAAAG
EEEECCCCEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
PAPRIADVVREVRAVVVAAHESALNAQLALTRLTLAGPGRPLAAGSQALVLPPAAAASGV
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCEEEECCHHHCCCC
PAPAVLTAGVPAAPAGLTAPAGPAVAAGRVAPDVAPTDPVATEAAFKPLARSGRRELTDA
CCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHH
DLAALVRGEVAGVFGPAYDQEGVNPDVRLTDPGEATLLTWVADLRLRGGSRTAGSLHAGL
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHEEEEHHHCCCCCCCCHHHHHHH
RALPGTAAPGSFAGAAGSGSLADALQAAAAQAAKVFALYAGLHLCLADARFVAGPPAEDA
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCC
DGGPRTGARPPAPTVALTADGGGWDGTGGELVLDVTAIDLIPRPWLAVRALVHAGGRLVA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCHHHH
EVRDVAVTVRERPGAPVGADHGGAVTAFLGRRTAAGERALLSEFHMAHCARGDQGVGLGP
HHHHHEEEEECCCCCCCCCCCCCEEEHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
EFAAYRGRRATRLPGGGLRLVDRVMAMDSRRGDLRGGATHVTEYDAAADCWYFTETANAS
HHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEEEEECCCCC
MPNCVYMETSLQAALMLGYYLGATLAQPAEDYSLRNLGGSATVLREVDLRDATIRQHSTL
CCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEECCCCHHHHHHHHHH
LSTNPMPGTALQDFSYELAVDGEPFYTGESMFGYFNAPALARQTGLDGGRLEPTWLDALD
EECCCCCCCHHHCCCEEEEECCCCCCCCCCCCEECCCCHHHHHCCCCCCCCCHHHHHHHH
ERERPPVRMIDVAARRADPAAPLCARGHLALLDDVEVVDGGGRFGQGYLRAVRPIDPADW
HCCCCCCHHHHHHHHCCCCCCCHHCCCCEEEECCEEEECCCCCCCCHHHHHCCCCCCHHH
FFARHFYLDPVIPGSLGVEAVIQAMQEWVIDAGHLAGLARPGFVLPVGVPLQWKYRGQLL
HHHHHEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCEEEEECCCEEEEECCEEC
PSDGTFTLEVHIKDVSHRPGRVRVTADASLWKPTMRIYELIDVAVELRDEGAPSW
CCCCEEEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA