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The map label for this gene is yisK [H]

Identifier: 158315716

GI number: 158315716

Start: 4697316

End: 4698203

Strand: Reverse

Name: yisK [H]

Synonym: Franean1_3928

Alternate gene names: 158315716

Gene position: 4698203-4697316 (Counterclockwise)

Preceding gene: 158315718

Following gene: 158315714

Centisome position: 52.31

GC content: 72.97

Gene sequence:

>888_bases
ATGCGGTTCGTGGGATTGCGGGACGGACGGCGGGTCGTGGTCGGCCTGGTGTTCGGTGCCGACGGGGCCGGCCCGCAGGG
CGGGCCCATGGGCACGGCCGGGGACGAACGCCCCCGGGTCGCCCGCGTCGCCGAGGTCGACGAGTTCTACGGAGACCTCG
CCGGCTGGACGGCGAAGGCCCGCCGGATGACCGCCGGTGAGCATGACCTCGCCGACGTCGAGCTCGTCCCGCCCGTACCG
GCCGGAGCCCGGATCCTCGGCATGGGGCTGAATTATCATGCGCACGCCGCGGAGACCGGGCTGGAACTGCCCAGGCGGCC
ACCGATCTTCGGCCGGTGGACCGCGTCCCTGACGGTGGACGGCACCCCCGTCCCCGTCCCGCCGGGCGAGCGGGGCCTGG
ACTGGGAGGGCGAGCTCGCCGTCATCGTCGGGTCCAGGATGACCGATGTCGACGAGGACGCCGCCCTGCGCGGCGTGTTC
GGCTACGCGGTGTTCAACGACCTCAGCGCCCGCCGCGCCCAGGGCGCCTCGGCGCAGTGGACGCTGGGCAAGAACTCCGA
CCGCAGCGGGCCGATGGGGCCCGTCGTGACCGCCGACGAGGTCGGCGATCCGGCGGCGGGCCTGCGGCTGGTCACCCGCG
TCAACGGCGAGGTGGTGCAGGACGGCGACACCAGCGACATGATCTTCTCGATCGGCCGGATCCTGTCGTTCGTGAGCCGC
ACCCTGACCCTCAACCCGGGTGACATCCTGATCACCGGAACTCCCGCCGGGGTCGGCTACATCCGCAAGCCGCCCCGCTA
CCTGGGTCCGGGTGATGTCGTCGAGGTGTGGATCGAGCGGGTGGGCACGATCCGCAACCCGGTCGTGGACGCGTCCGCCC
GGCCGTGA

Upstream 100 bases:

>100_bases
ACACGCGGGCGCCGGCTTCCTGGCGTCCCGTGGTGCACAATTCCGGTGTCCGATCCGAGCCGGGGCGGCCGGTGTCGCGG
TGGGAGGGAGGACGGGTTCG

Downstream 100 bases:

>100_bases
CCCGGCGGTGGGCCGAACCCGTGGCGGGTCGGGTCGGCCCACCACACCCGTGTTCCGCGTCAACGCGGGCCGGGGTCACC
GGGCACGTTCACGCCTTCGG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MRFVGLRDGRRVVVGLVFGADGAGPQGGPMGTAGDERPRVARVAEVDEFYGDLAGWTAKARRMTAGEHDLADVELVPPVP
AGARILGMGLNYHAHAAETGLELPRRPPIFGRWTASLTVDGTPVPVPPGERGLDWEGELAVIVGSRMTDVDEDAALRGVF
GYAVFNDLSARRAQGASAQWTLGKNSDRSGPMGPVVTADEVGDPAAGLRLVTRVNGEVVQDGDTSDMIFSIGRILSFVSR
TLTLNPGDILITGTPAGVGYIRKPPRYLGPGDVVEVWIERVGTIRNPVVDASARP

Sequences:

>Translated_295_residues
MRFVGLRDGRRVVVGLVFGADGAGPQGGPMGTAGDERPRVARVAEVDEFYGDLAGWTAKARRMTAGEHDLADVELVPPVP
AGARILGMGLNYHAHAAETGLELPRRPPIFGRWTASLTVDGTPVPVPPGERGLDWEGELAVIVGSRMTDVDEDAALRGVF
GYAVFNDLSARRAQGASAQWTLGKNSDRSGPMGPVVTADEVGDPAAGLRLVTRVNGEVVQDGDTSDMIFSIGRILSFVSR
TLTLNPGDILITGTPAGVGYIRKPPRYLGPGDVVEVWIERVGTIRNPVVDASARP
>Mature_295_residues
MRFVGLRDGRRVVVGLVFGADGAGPQGGPMGTAGDERPRVARVAEVDEFYGDLAGWTAKARRMTAGEHDLADVELVPPVP
AGARILGMGLNYHAHAAETGLELPRRPPIFGRWTASLTVDGTPVPVPPGERGLDWEGELAVIVGSRMTDVDEDAALRGVF
GYAVFNDLSARRAQGASAQWTLGKNSDRSGPMGPVVTADEVGDPAAGLRLVTRVNGEVVQDGDTSDMIFSIGRILSFVSR
TLTLNPGDILITGTPAGVGYIRKPPRYLGPGDVVEVWIERVGTIRNPVVDASARP

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=236, Percent_Identity=39.4067796610169, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI40786394, Length=238, Percent_Identity=39.0756302521008, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI66348062, Length=218, Percent_Identity=36.2385321100917, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI215422413, Length=186, Percent_Identity=38.7096774193548, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI13654274, Length=186, Percent_Identity=38.7096774193548, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=33.5164835164835, Blast_Score=101, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17557057, Length=198, Percent_Identity=33.8383838383838, Blast_Score=117, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6324161, Length=236, Percent_Identity=29.6610169491525, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28572127, Length=265, Percent_Identity=34.3396226415094, Blast_Score=151, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24663695, Length=225, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI28571789, Length=219, Percent_Identity=31.5068493150685, Blast_Score=112, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 31183; Mature: 31183

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVGLRDGRRVVVGLVFGADGAGPQGGPMGTAGDERPRVARVAEVDEFYGDLAGWTAKA
CEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRMTAGEHDLADVELVPPVPAGARILGMGLNYHAHAAETGLELPRRPPIFGRWTASLTVD
HHCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCEEEEEEEEEC
GTPVPVPPGERGLDWEGELAVIVGSRMTDVDEDAALRGVFGYAVFNDLSARRAQGASAQW
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
TLGKNSDRSGPMGPVVTADEVGDPAAGLRLVTRVNGEVVQDGDTSDMIFSIGRILSFVSR
EECCCCCCCCCCCCEEEHHCCCCCHHHEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHH
TLTLNPGDILITGTPAGVGYIRKPPRYLGPGDVVEVWIERVGTIRNPVVDASARP
HEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRFVGLRDGRRVVVGLVFGADGAGPQGGPMGTAGDERPRVARVAEVDEFYGDLAGWTAKA
CEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRMTAGEHDLADVELVPPVPAGARILGMGLNYHAHAAETGLELPRRPPIFGRWTASLTVD
HHCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCEEEEEEEEEC
GTPVPVPPGERGLDWEGELAVIVGSRMTDVDEDAALRGVFGYAVFNDLSARRAQGASAQW
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
TLGKNSDRSGPMGPVVTADEVGDPAAGLRLVTRVNGEVVQDGDTSDMIFSIGRILSFVSR
EECCCCCCCCCCCCEEEHHCCCCCHHHEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHH
TLTLNPGDILITGTPAGVGYIRKPPRYLGPGDVVEVWIERVGTIRNPVVDASARP
HEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]