Click here to switch to the map view.

The map label for this gene is choA [H]

Identifier: 158315689

GI number: 158315689

Start: 4665120

End: 4666745

Strand: Reverse

Name: choA [H]

Synonym: Franean1_3901

Alternate gene names: 158315689

Gene position: 4666745-4665120 (Counterclockwise)

Preceding gene: 158315690

Following gene: 158315688

Centisome position: 51.96

GC content: 69.25

Gene sequence:

>1626_bases
ATGCCCGAAAACACGCCCGACGCCGTCGAATCCACCCCCGGCCTCAACCGCAGGCACTTAATCGGCACGGCGGCGATCGG
CGCCGCCGCGGTCGGCGGTTTCACCGCGGGACCGGGTGCCGTCCGGGCCCGGGCCGCCACCCCCGTGCCGGCCACTGTGC
AGCAGGAGCGGGCCGTTGTCATCGGGAGCGGCTTCGGCGGCGGCGTGACCGCGCTGCGGCTGGCCCAGGTAGGCGTGTCG
ACGCTGGTCCTGGAGCGCGGGCTGCGGTGGCCCACCGGGCCGAACGCAACGACGTTCTGCCGCTTCGCCAACATCGACAA
CCGCTCCGCCTGGCTGACCGACCACGCCACGGTCGGCGGCGTGGTGAAGACGTGGGAGCCCTACACCGGGGTGATCGAGA
GCATTCCCGGCAACGGAATCACGGTGAACTGCGGGGCGGCCGTCGGCGGCGGCTCCCTCATGTACCACGGCATGACACTG
AAGCCCTCGAAGGCGAACTTCGCCGCGTCGATCCCGGTGGCCGCGAACCTCTACGACGAGCTGAACCTGTGGGCGTATCC
GCTGGTGGCCAGCATGCTGGGAGTCTCCACGATTCCCAACGACATCCTGAACAGCGACCCGTACAAGTCCTCCCGGCTCT
TCCGGGACGTCGCTCCGGGCGCGGGCCTGGAGCCGTTCCAGGTTCCCCTGCCGATCGACTGGCAGTACGTGCGCGGTGAG
CTGAACGGCCAGTACCAGCCGACCTACACCACCAGCGACATCGCCTTCGGGGTCAACAACGGCGGTAAGCGCTCCATCGA
CGTCACCTACCTCAAGGCGGCGGAGGCGACCGGCCGGGTCCGCGTCGCGACGCTGCACGTCGTCCGCGACATCGCGCTCG
ACGCGAACAAGAAGTGGGTACTGACGGTCGACCGCATCAACACCGGCGGCATCGTCCAGGAGACGAAGACCATCGTCGCG
GACGCGGTATTCCTCAACGCGGGTTCCGCCGGCACGACCCGCCTGCTGGTGAAGTCCAAGGCGAAGGGGCTTATCCCCAA
CCTGCCGGACGCCGTCGGAACCCAGTGGGGAAACAACGGCGACCGCATCTACCTGTGGAACGGCATGAACGGCGACATCG
GGACCCAGCAGGGTGGTCCCGCCTGCGTCGGCGGTCGCGACACCACCAGCTCGATCCCGCTCACCATCATCCACGCGGGC
TCCCCCATTCCGAGTACCGCCGGCAAGCTGATGACGGTCGTCGGCTTCGGGATCGTGAACCCCGCCGGCACCTGGGCGTA
CGACTCCGCGAAGGACGACGCCGTCCTGACCTGGCCGTCCAGCGGTGACGCCGCGCTGCAGGCGCTGATCGCCGCGCGCA
TGCAGAAGATCGCCCAGGTGGGCGGCGGCATCATGATCGACACGAACGCCCAGGCGAACTCGACCTGGCACGCCCTGGGC
GGCGTGCCCATGGGGTCCGCGGTCGACCTCTACGGCCGGGTCATCGGCCAGAGTGGCCTCTACGTGCTCGACGGCGCGCG
GATCCCGGGCTCCACCGGCGCCTGCAACCCGTCCATGACGATCGCGGCCCTCGCCGAGCACAGCATGGCCAAGATCGTGC
TCCAGGACGTCGGACGCGTCTTCTAG

Upstream 100 bases:

>100_bases
GACTTACGTCGGCGCACCCCCGCGGGCCGGTGGACCCTCGTCCACCCGCTCGCGGCCGAAGGATGCGCATCATGCCCGCA
ATTCAACTCTGGAGTCCACC

Downstream 100 bases:

>100_bases
GTTCCCGCTCCCGGCACGCCCCCGGGGGTACCGGATCCCGCGACCTGCGGAATCCGGTACCCCCGGCCCGCTGCGTCGGA
ACCGACGCCCGCGCGGCCGG

Product: cholesterol oxidase

Products: NA

Alternate protein names: CHOD [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MPENTPDAVESTPGLNRRHLIGTAAIGAAAVGGFTAGPGAVRARAATPVPATVQQERAVVIGSGFGGGVTALRLAQVGVS
TLVLERGLRWPTGPNATTFCRFANIDNRSAWLTDHATVGGVVKTWEPYTGVIESIPGNGITVNCGAAVGGGSLMYHGMTL
KPSKANFAASIPVAANLYDELNLWAYPLVASMLGVSTIPNDILNSDPYKSSRLFRDVAPGAGLEPFQVPLPIDWQYVRGE
LNGQYQPTYTTSDIAFGVNNGGKRSIDVTYLKAAEATGRVRVATLHVVRDIALDANKKWVLTVDRINTGGIVQETKTIVA
DAVFLNAGSAGTTRLLVKSKAKGLIPNLPDAVGTQWGNNGDRIYLWNGMNGDIGTQQGGPACVGGRDTTSSIPLTIIHAG
SPIPSTAGKLMTVVGFGIVNPAGTWAYDSAKDDAVLTWPSSGDAALQALIAARMQKIAQVGGGIMIDTNAQANSTWHALG
GVPMGSAVDLYGRVIGQSGLYVLDGARIPGSTGACNPSMTIAALAEHSMAKIVLQDVGRVF

Sequences:

>Translated_541_residues
MPENTPDAVESTPGLNRRHLIGTAAIGAAAVGGFTAGPGAVRARAATPVPATVQQERAVVIGSGFGGGVTALRLAQVGVS
TLVLERGLRWPTGPNATTFCRFANIDNRSAWLTDHATVGGVVKTWEPYTGVIESIPGNGITVNCGAAVGGGSLMYHGMTL
KPSKANFAASIPVAANLYDELNLWAYPLVASMLGVSTIPNDILNSDPYKSSRLFRDVAPGAGLEPFQVPLPIDWQYVRGE
LNGQYQPTYTTSDIAFGVNNGGKRSIDVTYLKAAEATGRVRVATLHVVRDIALDANKKWVLTVDRINTGGIVQETKTIVA
DAVFLNAGSAGTTRLLVKSKAKGLIPNLPDAVGTQWGNNGDRIYLWNGMNGDIGTQQGGPACVGGRDTTSSIPLTIIHAG
SPIPSTAGKLMTVVGFGIVNPAGTWAYDSAKDDAVLTWPSSGDAALQALIAARMQKIAQVGGGIMIDTNAQANSTWHALG
GVPMGSAVDLYGRVIGQSGLYVLDGARIPGSTGACNPSMTIAALAEHSMAKIVLQDVGRVF
>Mature_540_residues
PENTPDAVESTPGLNRRHLIGTAAIGAAAVGGFTAGPGAVRARAATPVPATVQQERAVVIGSGFGGGVTALRLAQVGVST
LVLERGLRWPTGPNATTFCRFANIDNRSAWLTDHATVGGVVKTWEPYTGVIESIPGNGITVNCGAAVGGGSLMYHGMTLK
PSKANFAASIPVAANLYDELNLWAYPLVASMLGVSTIPNDILNSDPYKSSRLFRDVAPGAGLEPFQVPLPIDWQYVRGEL
NGQYQPTYTTSDIAFGVNNGGKRSIDVTYLKAAEATGRVRVATLHVVRDIALDANKKWVLTVDRINTGGIVQETKTIVAD
AVFLNAGSAGTTRLLVKSKAKGLIPNLPDAVGTQWGNNGDRIYLWNGMNGDIGTQQGGPACVGGRDTTSSIPLTIIHAGS
PIPSTAGKLMTVVGFGIVNPAGTWAYDSAKDDAVLTWPSSGDAALQALIAARMQKIAQVGGGIMIDTNAQANSTWHALGG
VPMGSAVDLYGRVIGQSGLYVLDGARIPGSTGACNPSMTIAALAEHSMAKIVLQDVGRVF

Specific function: Unknown

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867
- InterPro:   IPR006311 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.3.6 [H]

Molecular weight: Translated: 56152; Mature: 56020

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENTPDAVESTPGLNRRHLIGTAAIGAAAVGGFTAGPGAVRARAATPVPATVQQERAVV
CCCCCCCHHHCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCEEE
IGSGFGGGVTALRLAQVGVSTLVLERGLRWPTGPNATTFCRFANIDNRSAWLTDHATVGG
EECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCC
VVKTWEPYTGVIESIPGNGITVNCGAAVGGGSLMYHGMTLKPSKANFAASIPVAANLYDE
EEECCCCHHHHHHCCCCCCEEEECCCEECCCCEEEECEEECCCCCCCEEECCCCCCHHHH
LNLWAYPLVASMLGVSTIPNDILNSDPYKSSRLFRDVAPGAGLEPFQVPLPIDWQYVRGE
HHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHCCCCCCCCCEECCCCCCHHEEEEC
LNGQYQPTYTTSDIAFGVNNGGKRSIDVTYLKAAEATGRVRVATLHVVRDIALDANKKWV
CCCEECCCEECCCEEEECCCCCCEEEEEEEEEECCCCCCEEEEEEEEHHHHHCCCCCEEE
LTVDRINTGGIVQETKTIVADAVFLNAGSAGTTRLLVKSKAKGLIPNLPDAVGTQWGNNG
EEEEECCCCCCHHHHHHHHEEEEEEECCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCC
DRIYLWNGMNGDIGTQQGGPACVGGRDTTSSIPLTIIHAGSPIPSTAGKLMTVVGFGIVN
CEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCHHHHHEEEHHHCCCC
PAGTWAYDSAKDDAVLTWPSSGDAALQALIAARMQKIAQVGGGIMIDTNAQANSTWHALG
CCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEC
GVPMGSAVDLYGRVIGQSGLYVLDGARIPGSTGACNPSMTIAALAEHSMAKIVLQDVGRV
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
F
C
>Mature Secondary Structure 
PENTPDAVESTPGLNRRHLIGTAAIGAAAVGGFTAGPGAVRARAATPVPATVQQERAVV
CCCCCCHHHCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCEEE
IGSGFGGGVTALRLAQVGVSTLVLERGLRWPTGPNATTFCRFANIDNRSAWLTDHATVGG
EECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCC
VVKTWEPYTGVIESIPGNGITVNCGAAVGGGSLMYHGMTLKPSKANFAASIPVAANLYDE
EEECCCCHHHHHHCCCCCCEEEECCCEECCCCEEEECEEECCCCCCCEEECCCCCCHHHH
LNLWAYPLVASMLGVSTIPNDILNSDPYKSSRLFRDVAPGAGLEPFQVPLPIDWQYVRGE
HHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHCCCCCCCCCEECCCCCCHHEEEEC
LNGQYQPTYTTSDIAFGVNNGGKRSIDVTYLKAAEATGRVRVATLHVVRDIALDANKKWV
CCCEECCCEECCCEEEECCCCCCEEEEEEEEEECCCCCCEEEEEEEEHHHHHCCCCCEEE
LTVDRINTGGIVQETKTIVADAVFLNAGSAGTTRLLVKSKAKGLIPNLPDAVGTQWGNNG
EEEEECCCCCCHHHHHHHHEEEEEEECCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCC
DRIYLWNGMNGDIGTQQGGPACVGGRDTTSSIPLTIIHAGSPIPSTAGKLMTVVGFGIVN
CEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCHHHHHEEEHHHCCCC
PAGTWAYDSAKDDAVLTWPSSGDAALQALIAARMQKIAQVGGGIMIDTNAQANSTWHALG
CCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEC
GVPMGSAVDLYGRVIGQSGLYVLDGARIPGSTGACNPSMTIAALAEHSMAKIVLQDVGRV
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2914858; 10194345 [H]