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The map label for this gene is iniA [H]

Identifier: 158315598

GI number: 158315598

Start: 4520533

End: 4522470

Strand: Reverse

Name: iniA [H]

Synonym: Franean1_3807

Alternate gene names: 158315598

Gene position: 4522470-4520533 (Counterclockwise)

Preceding gene: 158315600

Following gene: 158315597

Centisome position: 50.35

GC content: 73.99

Gene sequence:

>1938_bases
ATGACGGGACCGAGCGGCGATTCAAGGTCCACACAATTTCCGCCCCCGCCAGACGCGATCCGGCTGCTCGACACGGTGGT
GGCGGAGGCGGCCCGGCGCCGCCGGGCGGACCTGCAGGCGCGGCTCGCCGGGGAACGCGGGCGGCTGGAGACGTCGACCT
GCCTCGTGGCCGTGGTCGGCGAGTTCAAGAAGGGCAAGGGCACGCTCATCAACGCGCTGCTGGACATGCGGGTGTGCGGC
ACTGACCCGGTGGCCACGACGCTGGTACCCACGCTCGTCAGGTACGCGCCACGGGCAACGGCGACGCTGCGGCGCGCCGC
GCCCGCCTCGGACGGCTCGGCCGACAGCGCTGCCCCGCCGTCCACCCGTCCCACCGACGAGCCGGTCACCATCACAGCTC
TCCACGAGGTCACCCAGGCGGCCGCCGCGGAGGGGCGGGGGGCGTCCATCACCACGGTGACCGGGGCGGAGATCGGGATC
CCGCGCCGGTTGTTGGAGTCGGGCCTGCTGCTGCTCGACACGCCGGGCCTGAACGGCGGGCTCGCCGACGGCCGGGCCAC
CGCTACCCTGCGCGCCGCCGCCGGCGCGGACGCGGTGGTGTTCGTCTCGGACGCGAGCCAGGAGCTCACCGCACCCGAAC
TCGAACTGCTGCGCCGGCTGGTGCGGCTGTGCCCGGCGGTCGTGCTGGCTCTCGCCAAGGTCGACGTCTACCCGCACTGG
CGGCGCATCCGCGACACGAACCTCGCCCACCTGCGCCGTTCGCGACTGGAGCTGCCGATCTTCCCGCTGGCGGCCCCGCT
GCGCCATCATGCGCTGCGAGCCGGCCGGTCCGATCTGGACGGCGAATCGGGGTATCCGGCTCTCGCCGCCATCCTGCGGG
ACGACATCGTCGGCGGGCGACGCGCCCGGCTGGAGAAGATCGCGGCGGAGGCGGCCACGGACGCCCTCGGGCAGATGCTC
GCCGAACTCGAGACGGAACGGGCGACCCTCGCCGACCCGGCGGCGGCACGGGAGCTGCGGGCCAAGCTCGAGGAGGCCGA
GCAGCGCGCCAAGGGGATGAGCGAGGCCGCCGCCACCTGGCGACGGGTGCTGGGCGACCGGTCCCAGGACATGACCGCGC
GGGTGCGGGACGACCTCGACAACCGGCTGCGCAATCTGGAATCGGCGGTGGCCAGGCGGATCGAGACAAGCGAGCCGGCG
CGCGACTGGGACGACCTGCGCGGCTGGCTGTACCGGCAGACCAACGACGCCCTGCTGACCCACCGGATGATGATCCGGTC
CGAGGCGGAAGCCCTGGTCACCGCCGTCACCCGGGAGTTCGAGGCGGATTCGGAGCGGGTGCGCGCACTCCTGGACGCGG
CTACCGGGCTGCCTCTCGGCACCATCACCGAAGGGCACGACCCGGAGTTCCAGCGGGTCGGCGGTGTGGACCTGCTCGCC
CAGGGGGCCCGCGGCGGCGGCATCGGGCTGATGATCGTCTCCGTGGGCGGGACTGTGGCCAGCATCGCCGGGTTCGCGGC
GGCGTCAGTGCTACTCGCGCCGGTGGGCATCGGCGTCGTGGTCGTCCTCGGCCGGCGGACGATCGCCTCGATCCGGGAGA
ACGAGGTGCGCGTCCACCGGGCGAACGCGCTGAAGACCGCCCGCGAGTACCTCGCCGAGACCCGCCGGGTCGCCGCCCAG
GACTCGGCGACCGCCCGCGAACAGATCTACCGCAATCTCCGCGACACCCTCACCGAGCAGGCGGCCGAGCTGTCCACCTC
CGCCCAGCGGAACAAGGAGGCCTCGGCACGCTCGATCAAGGCGACCTGGGAGTCGCGCCGGGCCCGGCTCGCGGCGGTGG
AGGCGGAGGTCGCCCGGCTGCGCTCGCTGGTGGGCACAGCCGGGGCGGCCGGCACAGTCAGCACCGCCGGCACCGCCGAC
ACGGGGATGGCGCCGTGA

Upstream 100 bases:

>100_bases
CCAGTCCTCCCGCCCGCGTCGCCTGGTCGTCGGGGCGCACCACATATGGCACATGGCTCTCAAGACCGGCCCACGGTCAC
ACGGCACTTGAGAAAAACTC

Downstream 100 bases:

>100_bases
CCGGCCCCGGGCAGGGCGGGCTGCGGGAACAGGTCCGCGCGCTGCTGTCCGACGCGGTCGACGCCTACCGCGGCACCCCC
GCCGAGGCGCTGCTCCGTCA

Product: dynamin family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MTGPSGDSRSTQFPPPPDAIRLLDTVVAEAARRRRADLQARLAGERGRLETSTCLVAVVGEFKKGKGTLINALLDMRVCG
TDPVATTLVPTLVRYAPRATATLRRAAPASDGSADSAAPPSTRPTDEPVTITALHEVTQAAAAEGRGASITTVTGAEIGI
PRRLLESGLLLLDTPGLNGGLADGRATATLRAAAGADAVVFVSDASQELTAPELELLRRLVRLCPAVVLALAKVDVYPHW
RRIRDTNLAHLRRSRLELPIFPLAAPLRHHALRAGRSDLDGESGYPALAAILRDDIVGGRRARLEKIAAEAATDALGQML
AELETERATLADPAAARELRAKLEEAEQRAKGMSEAAATWRRVLGDRSQDMTARVRDDLDNRLRNLESAVARRIETSEPA
RDWDDLRGWLYRQTNDALLTHRMMIRSEAEALVTAVTREFEADSERVRALLDAATGLPLGTITEGHDPEFQRVGGVDLLA
QGARGGGIGLMIVSVGGTVASIAGFAAASVLLAPVGIGVVVVLGRRTIASIRENEVRVHRANALKTAREYLAETRRVAAQ
DSATAREQIYRNLRDTLTEQAAELSTSAQRNKEASARSIKATWESRRARLAAVEAEVARLRSLVGTAGAAGTVSTAGTAD
TGMAP

Sequences:

>Translated_645_residues
MTGPSGDSRSTQFPPPPDAIRLLDTVVAEAARRRRADLQARLAGERGRLETSTCLVAVVGEFKKGKGTLINALLDMRVCG
TDPVATTLVPTLVRYAPRATATLRRAAPASDGSADSAAPPSTRPTDEPVTITALHEVTQAAAAEGRGASITTVTGAEIGI
PRRLLESGLLLLDTPGLNGGLADGRATATLRAAAGADAVVFVSDASQELTAPELELLRRLVRLCPAVVLALAKVDVYPHW
RRIRDTNLAHLRRSRLELPIFPLAAPLRHHALRAGRSDLDGESGYPALAAILRDDIVGGRRARLEKIAAEAATDALGQML
AELETERATLADPAAARELRAKLEEAEQRAKGMSEAAATWRRVLGDRSQDMTARVRDDLDNRLRNLESAVARRIETSEPA
RDWDDLRGWLYRQTNDALLTHRMMIRSEAEALVTAVTREFEADSERVRALLDAATGLPLGTITEGHDPEFQRVGGVDLLA
QGARGGGIGLMIVSVGGTVASIAGFAAASVLLAPVGIGVVVVLGRRTIASIRENEVRVHRANALKTAREYLAETRRVAAQ
DSATAREQIYRNLRDTLTEQAAELSTSAQRNKEASARSIKATWESRRARLAAVEAEVARLRSLVGTAGAAGTVSTAGTAD
TGMAP
>Mature_644_residues
TGPSGDSRSTQFPPPPDAIRLLDTVVAEAARRRRADLQARLAGERGRLETSTCLVAVVGEFKKGKGTLINALLDMRVCGT
DPVATTLVPTLVRYAPRATATLRRAAPASDGSADSAAPPSTRPTDEPVTITALHEVTQAAAAEGRGASITTVTGAEIGIP
RRLLESGLLLLDTPGLNGGLADGRATATLRAAAGADAVVFVSDASQELTAPELELLRRLVRLCPAVVLALAKVDVYPHWR
RIRDTNLAHLRRSRLELPIFPLAAPLRHHALRAGRSDLDGESGYPALAAILRDDIVGGRRARLEKIAAEAATDALGQMLA
ELETERATLADPAAARELRAKLEEAEQRAKGMSEAAATWRRVLGDRSQDMTARVRDDLDNRLRNLESAVARRIETSEPAR
DWDDLRGWLYRQTNDALLTHRMMIRSEAEALVTAVTREFEADSERVRALLDAATGLPLGTITEGHDPEFQRVGGVDLLAQ
GARGGGIGLMIVSVGGTVASIAGFAAASVLLAPVGIGVVVVLGRRTIASIRENEVRVHRANALKTAREYLAETRRVAAQD
SATAREQIYRNLRDTLTEQAAELSTSAQRNKEASARSIKATWESRRARLAAVEAEVARLRSLVGTAGAAGTVSTAGTADT
GMAP

Specific function: Participates in the development of tolerance to both isoniazid and ethambutol. May function through a MDR-pump like mechanism, although it does not appear to directly transport isoniazid from the cell [H]

COG id: COG0699

COG function: function code R; Predicted GTPases (dynamin-related)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001401 [H]

Pfam domain/function: PF00350 Dynamin_N [H]

EC number: NA

Molecular weight: Translated: 68718; Mature: 68587

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPSGDSRSTQFPPPPDAIRLLDTVVAEAARRRRADLQARLAGERGRLETSTCLVAVVG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EFKKGKGTLINALLDMRVCGTDPVATTLVPTLVRYAPRATATLRRAAPASDGSADSAAPP
HHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC
STRPTDEPVTITALHEVTQAAAAEGRGASITTVTGAEIGIPRRLLESGLLLLDTPGLNGG
CCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHCCCEEEECCCCCCC
LADGRATATLRAAAGADAVVFVSDASQELTAPELELLRRLVRLCPAVVLALAKVDVYPHW
CCCCCHHHEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RRIRDTNLAHLRRSRLELPIFPLAAPLRHHALRAGRSDLDGESGYPALAAILRDDIVGGR
HHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCH
RARLEKIAAEAATDALGQMLAELETERATLADPAAARELRAKLEEAEQRAKGMSEAAATW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RRVLGDRSQDMTARVRDDLDNRLRNLESAVARRIETSEPARDWDDLRGWLYRQTNDALLT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHH
HRMMIRSEAEALVTAVTREFEADSERVRALLDAATGLPLGTITEGHDPEFQRVGGVDLLA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHH
QGARGGGIGLMIVSVGGTVASIAGFAAASVLLAPVGIGVVVVLGRRTIASIRENEVRVHR
CCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ANALKTAREYLAETRRVAAQDSATAREQIYRNLRDTLTEQAAELSTSAQRNKEASARSIK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATWESRRARLAAVEAEVARLRSLVGTAGAAGTVSTAGTADTGMAP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGPSGDSRSTQFPPPPDAIRLLDTVVAEAARRRRADLQARLAGERGRLETSTCLVAVVG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EFKKGKGTLINALLDMRVCGTDPVATTLVPTLVRYAPRATATLRRAAPASDGSADSAAPP
HHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC
STRPTDEPVTITALHEVTQAAAAEGRGASITTVTGAEIGIPRRLLESGLLLLDTPGLNGG
CCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHCCCEEEECCCCCCC
LADGRATATLRAAAGADAVVFVSDASQELTAPELELLRRLVRLCPAVVLALAKVDVYPHW
CCCCCHHHEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RRIRDTNLAHLRRSRLELPIFPLAAPLRHHALRAGRSDLDGESGYPALAAILRDDIVGGR
HHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCH
RARLEKIAAEAATDALGQMLAELETERATLADPAAARELRAKLEEAEQRAKGMSEAAATW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RRVLGDRSQDMTARVRDDLDNRLRNLESAVARRIETSEPARDWDDLRGWLYRQTNDALLT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHH
HRMMIRSEAEALVTAVTREFEADSERVRALLDAATGLPLGTITEGHDPEFQRVGGVDLLA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHH
QGARGGGIGLMIVSVGGTVASIAGFAAASVLLAPVGIGVVVVLGRRTIASIRENEVRVHR
CCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ANALKTAREYLAETRRVAAQDSATAREQIYRNLRDTLTEQAAELSTSAQRNKEASARSIK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATWESRRARLAAVEAEVARLRSLVGTAGAAGTVSTAGTADTGMAP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]