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The map label for this gene is iolS [H]

Identifier: 158315575

GI number: 158315575

Start: 4487024

End: 4488085

Strand: Reverse

Name: iolS [H]

Synonym: Franean1_3784

Alternate gene names: 158315575

Gene position: 4488085-4487024 (Counterclockwise)

Preceding gene: 158315582

Following gene: 158315574

Centisome position: 49.97

GC content: 73.16

Gene sequence:

>1062_bases
ATGAATGGTCCCTGCCGCGGCGTCGCCCGCCGCAGCAGACTGGCGGTCATGACGCAGACGACGATGACGACAAGGCGGCT
CGGGGCAACCGGGCCGGAGGTGGGTGCGCTCGGGCTCGGTTGCATGGGCATGTCCGGCATGTACGGGCCAGCCGACGACG
ATGAGAGCGTGGCGACGATCCTCGCCGCGGTCGACGCGGGGATGACCCTGCTCGACACCGGCGACTTCTACGGCATGGGA
CACAACGAGCTGCTGGTCGGCCGCGCCCTGCGCCAGCTCGACCGGGACGCGGTGACGGTGAGCGTGAAGTTCGGGGCGCT
GCGCGACGCGGTCGGCGGCTGGGGTGGTCTCGACGCCCGGCCGGCGGCGCTGCGCAACTTCCTCGCCTACTCGCTGGTGC
GCCTGGGCACCGACCATGTGGACGTCTACCGGCCGGCCCGGCTCGACCCCGCCGTGCCGATCGAGGAGACGATCGGTGCC
ATCGCCGAGCAGGTCAAGGCCGGTCTGGTCCGGCACATCGGCCTGTCGGAGGTCGGCCCGGAGACGATCCGGCGGGCGGC
GGCCGTGCACCCGATCTGCGACCTGCAGATCGAGTACTCGGTGCTTTCCCGCGGCATCGAGGACGAGATCCTGGCGACCT
GCCGCGAGCTCGGGATCGCGATCACCGCGTACGGGGTGCTCTCCCGCGGGCTGATCGCCGGCACCGGCCCGTCGGGGCAC
AGCAACGACTTCCGGGCACACAGCCCGCGCTTCCAGGGCGCGAACCTCGACCACAACCTGGGGCTCGTCGAGCGGCTGCG
GCCGGTCGCCGAGCGCCACGGGATCTCCGTCGCGCAGCTGGCCATCGCCTGGGTCGCCGCCGCAGGTCCGGACGTCATCC
CGCTGGTGGGGATGCGCCGGCGCAGCCGCATCGATGACGCCCTGGCCGCCGCGGCCGTCACCCTGTCCGAGCAGGATCTG
GCCGACGTCGACCGGGCGGTGCCCGCCGGGTCGGCCGCGGGCGGACGATACGAGGACGCCCAGCTCGCCGCCCTCGACAG
CGAGCGTCCCGCCGAGCGCTGA

Upstream 100 bases:

>100_bases
TGCGCGCGGCGCCGGCGCAGGAAGTCGGCGAGCCCGGAGCGATCCATGCCACCAGTGTTCCCCACGCCCGGCAGCCGAGC
CAGGGACCGGCGATCCCACG

Downstream 100 bases:

>100_bases
CGCGGCCCCGCCAAGCCCGCCCACGCACAGGTGGTGCACAGGGAACGCACAGCGTAGGCATCGCCGGGCCCGCCATGATC
GAGCCATCAGGTCAGCCGAT

Product: aldo/keto reductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MNGPCRGVARRSRLAVMTQTTMTTRRLGATGPEVGALGLGCMGMSGMYGPADDDESVATILAAVDAGMTLLDTGDFYGMG
HNELLVGRALRQLDRDAVTVSVKFGALRDAVGGWGGLDARPAALRNFLAYSLVRLGTDHVDVYRPARLDPAVPIEETIGA
IAEQVKAGLVRHIGLSEVGPETIRRAAAVHPICDLQIEYSVLSRGIEDEILATCRELGIAITAYGVLSRGLIAGTGPSGH
SNDFRAHSPRFQGANLDHNLGLVERLRPVAERHGISVAQLAIAWVAAAGPDVIPLVGMRRRSRIDDALAAAAVTLSEQDL
ADVDRAVPAGSAAGGRYEDAQLAALDSERPAER

Sequences:

>Translated_353_residues
MNGPCRGVARRSRLAVMTQTTMTTRRLGATGPEVGALGLGCMGMSGMYGPADDDESVATILAAVDAGMTLLDTGDFYGMG
HNELLVGRALRQLDRDAVTVSVKFGALRDAVGGWGGLDARPAALRNFLAYSLVRLGTDHVDVYRPARLDPAVPIEETIGA
IAEQVKAGLVRHIGLSEVGPETIRRAAAVHPICDLQIEYSVLSRGIEDEILATCRELGIAITAYGVLSRGLIAGTGPSGH
SNDFRAHSPRFQGANLDHNLGLVERLRPVAERHGISVAQLAIAWVAAAGPDVIPLVGMRRRSRIDDALAAAAVTLSEQDL
ADVDRAVPAGSAAGGRYEDAQLAALDSERPAER
>Mature_353_residues
MNGPCRGVARRSRLAVMTQTTMTTRRLGATGPEVGALGLGCMGMSGMYGPADDDESVATILAAVDAGMTLLDTGDFYGMG
HNELLVGRALRQLDRDAVTVSVKFGALRDAVGGWGGLDARPAALRNFLAYSLVRLGTDHVDVYRPARLDPAVPIEETIGA
IAEQVKAGLVRHIGLSEVGPETIRRAAAVHPICDLQIEYSVLSRGIEDEILATCRELGIAITAYGVLSRGLIAGTGPSGH
SNDFRAHSPRFQGANLDHNLGLVERLRPVAERHGISVAQLAIAWVAAAGPDVIPLVGMRRRSRIDDALAAAAVTLSEQDL
ADVDRAVPAGSAAGGRYEDAQLAALDSERPAER

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=286, Percent_Identity=28.3216783216783, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI4504825, Length=283, Percent_Identity=28.2685512367491, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI27436964, Length=291, Percent_Identity=27.1477663230241, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI27436962, Length=291, Percent_Identity=26.8041237113402, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI27436966, Length=309, Percent_Identity=26.2135922330097, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27436971, Length=330, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1788070, Length=314, Percent_Identity=30.2547770700637, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87081735, Length=321, Percent_Identity=31.4641744548287, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1789375, Length=331, Percent_Identity=28.3987915407855, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787674, Length=313, Percent_Identity=28.1150159744409, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788081, Length=277, Percent_Identity=27.4368231046931, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789199, Length=343, Percent_Identity=27.1137026239067, Blast_Score=78, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=331, Percent_Identity=26.8882175226586, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6325384, Length=303, Percent_Identity=28.0528052805281, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323998, Length=302, Percent_Identity=24.5033112582781, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319958, Length=297, Percent_Identity=24.5791245791246, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=208, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646159, Length=311, Percent_Identity=24.7588424437299, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24646155, Length=308, Percent_Identity=25.6493506493506, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37154; Mature: 37154

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGPCRGVARRSRLAVMTQTTMTTRRLGATGPEVGALGLGCMGMSGMYGPADDDESVATI
CCCCCHHHHHHHHEEEEEHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHH
LAAVDAGMTLLDTGDFYGMGHNELLVGRALRQLDRDAVTVSVKFGALRDAVGGWGGLDAR
HHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHHCCCCCCCCC
PAALRNFLAYSLVRLGTDHVDVYRPARLDPAVPIEETIGAIAEQVKAGLVRHIGLSEVGP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCH
ETIRRAAAVHPICDLQIEYSVLSRGIEDEILATCRELGIAITAYGVLSRGLIAGTGPSGH
HHHHHHHHCCCHHCCEEEHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHCCEEECCCCCCC
SNDFRAHSPRFQGANLDHNLGLVERLRPVAERHGISVAQLAIAWVAAAGPDVIPLVGMRR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHCCCHH
RSRIDDALAAAAVTLSEQDLADVDRAVPAGSAAGGRYEDAQLAALDSERPAER
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MNGPCRGVARRSRLAVMTQTTMTTRRLGATGPEVGALGLGCMGMSGMYGPADDDESVATI
CCCCCHHHHHHHHEEEEEHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHH
LAAVDAGMTLLDTGDFYGMGHNELLVGRALRQLDRDAVTVSVKFGALRDAVGGWGGLDAR
HHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHHCCCCCCCCC
PAALRNFLAYSLVRLGTDHVDVYRPARLDPAVPIEETIGAIAEQVKAGLVRHIGLSEVGP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCH
ETIRRAAAVHPICDLQIEYSVLSRGIEDEILATCRELGIAITAYGVLSRGLIAGTGPSGH
HHHHHHHHCCCHHCCEEEHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHCCEEECCCCCCC
SNDFRAHSPRFQGANLDHNLGLVERLRPVAERHGISVAQLAIAWVAAAGPDVIPLVGMRR
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHCCCHH
RSRIDDALAAAAVTLSEQDLADVDRAVPAGSAAGGRYEDAQLAALDSERPAER
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]