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The map label for this gene is tfdA [H]

Identifier: 158315509

GI number: 158315509

Start: 4396129

End: 4396956

Strand: Reverse

Name: tfdA [H]

Synonym: Franean1_3714

Alternate gene names: 158315509

Gene position: 4396956-4396129 (Counterclockwise)

Preceding gene: 158315510

Following gene: 158315508

Centisome position: 48.95

GC content: 65.94

Gene sequence:

>828_bases
ATGACCGCGATCACTACGAGAAAACTGAACGATTATGTCGGAGCGGAGGTTGTCGGCCTCGACGTCGACCGTCTACTGAA
CGACAGCGACGTGCCGGCAGCGTGCCTAGCGGCGCTCGAAGAACACGGTGTTCTGTTATTCCGCGAGTTGAACATCAGCC
ATCAGGACCAGCTCGCGTTCGGTCGGAAGCTCGGCGACGTCGTCAAGATTCCCGGCTATCCGATCCCCGAGGTCATGGAG
ATCAGCTTCGACCCGGCCAATCCGAACGCGCAGTACTTCCCGAGCAACGACCACTGGCACTTCGACGGCTCCATGGACGA
CATCCCGGCCAAGGCCGCGCTGATGAGCGCGAGCGTGGTCGTCGCGGAGGGCGGCGAGACGGAGTTCGCCAGCACCTACG
TGGCCTACGACACCCTCTCCGACGAGGAGAAGGAGCGTTTCGACGATCTCCGGGTGGTCCACACGTTCGAGTCGATCCAG
CGCCGGAGCTACCCCGATCCGACGCCGGAGCAGAAGGCCGACTGGGCGTCGTGGCCCGTGCGTGAGCACCCGCTGGTGTG
GGAGCACCAGTCGAGGCGGCGTTCGCTGGTGTTCGGGGCGAGCGCGTCGCACATCGTCGGGATGGACGTCGACGAGGGCC
GGGCGCTGCTCGCGGACCTTGAGCGGCGGAGCACGCTGCCGGACCGGGTGCTGCGGCACTCCTGGTCGGTGGGAGACATG
GTGATCTGGGACAACCGGGGGCTGGTCCACCGGGCCTGCCCCTTCGACCGGACGAAGCCGCGCACCATGCACCGCACGAC
CCTCGCCGGAGATGAGCCGATCAAATGA

Upstream 100 bases:

>100_bases
ACGACGAGTTCCGGACCTGGTACGCAGAGGGAATGCAGTAGGGAATGCAATGGCTCCCGGGAGCACGGCGACCGGGAGCA
AGCGAGAGGAGGCGGGAAGG

Downstream 100 bases:

>100_bases
GCGCACGTACAGCCATCGTCACCGGAGGCGCGTCGGGCATCGGCGGTGGCATCAGCCAGCGCCTGGCGGCCGACGGCGCC
ATGGTAGCGATCTTCGACCT

Product: taurine catabolism dioxygenase TauD/TfdA

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: 2,4-D dioxygenase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTAITTRKLNDYVGAEVVGLDVDRLLNDSDVPAACLAALEEHGVLLFRELNISHQDQLAFGRKLGDVVKIPGYPIPEVME
ISFDPANPNAQYFPSNDHWHFDGSMDDIPAKAALMSASVVVAEGGETEFASTYVAYDTLSDEEKERFDDLRVVHTFESIQ
RRSYPDPTPEQKADWASWPVREHPLVWEHQSRRRSLVFGASASHIVGMDVDEGRALLADLERRSTLPDRVLRHSWSVGDM
VIWDNRGLVHRACPFDRTKPRTMHRTTLAGDEPIK

Sequences:

>Translated_275_residues
MTAITTRKLNDYVGAEVVGLDVDRLLNDSDVPAACLAALEEHGVLLFRELNISHQDQLAFGRKLGDVVKIPGYPIPEVME
ISFDPANPNAQYFPSNDHWHFDGSMDDIPAKAALMSASVVVAEGGETEFASTYVAYDTLSDEEKERFDDLRVVHTFESIQ
RRSYPDPTPEQKADWASWPVREHPLVWEHQSRRRSLVFGASASHIVGMDVDEGRALLADLERRSTLPDRVLRHSWSVGDM
VIWDNRGLVHRACPFDRTKPRTMHRTTLAGDEPIK
>Mature_274_residues
TAITTRKLNDYVGAEVVGLDVDRLLNDSDVPAACLAALEEHGVLLFRELNISHQDQLAFGRKLGDVVKIPGYPIPEVMEI
SFDPANPNAQYFPSNDHWHFDGSMDDIPAKAALMSASVVVAEGGETEFASTYVAYDTLSDEEKERFDDLRVVHTFESIQR
RSYPDPTPEQKADWASWPVREHPLVWEHQSRRRSLVFGASASHIVGMDVDEGRALLADLERRSTLPDRVLRHSWSVGDMV
IWDNRGLVHRACPFDRTKPRTMHRTTLAGDEPIK

Specific function: Involved in degradation of the herbicide 2,4- dichlorophenoxyacetic acid (2,4-D). Is also able to degrade 2- methyl-4-chlorophenoxyacetic acid and 3-chlorobenzoic acid [H]

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=283, Percent_Identity=31.095406360424, Blast_Score=117, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6322971, Length=292, Percent_Identity=27.0547945205479, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 30989; Mature: 30858

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAITTRKLNDYVGAEVVGLDVDRLLNDSDVPAACLAALEEHGVLLFRELNISHQDQLAF
CCCCCCCHHHHHCCCEEEEECHHHHCCCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHH
GRKLGDVVKIPGYPIPEVMEISFDPANPNAQYFPSNDHWHFDGSMDDIPAKAALMSASVV
HHHCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHEEEEE
VAEGGETEFASTYVAYDTLSDEEKERFDDLRVVHTFESIQRRSYPDPTPEQKADWASWPV
EECCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
REHPLVWEHQSRRRSLVFGASASHIVGMDVDEGRALLADLERRSTLPDRVLRHSWSVGDM
CCCCEEECCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCE
VIWDNRGLVHRACPFDRTKPRTMHRTTLAGDEPIK
EEECCCCCEEECCCCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
TAITTRKLNDYVGAEVVGLDVDRLLNDSDVPAACLAALEEHGVLLFRELNISHQDQLAF
CCCCCCHHHHHCCCEEEEECHHHHCCCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHH
GRKLGDVVKIPGYPIPEVMEISFDPANPNAQYFPSNDHWHFDGSMDDIPAKAALMSASVV
HHHCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHEEEEE
VAEGGETEFASTYVAYDTLSDEEKERFDDLRVVHTFESIQRRSYPDPTPEQKADWASWPV
EECCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
REHPLVWEHQSRRRSLVFGASASHIVGMDVDEGRALLADLERRSTLPDRVLRHSWSVGDM
CCCCEEECCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCE
VIWDNRGLVHRACPFDRTKPRTMHRTTLAGDEPIK
EEECCCCCEEECCCCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8779585 [H]