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The map label for this gene is ahpC [C]

Identifier: 158315461

GI number: 158315461

Start: 4343266

End: 4343892

Strand: Reverse

Name: ahpC [C]

Synonym: Franean1_3666

Alternate gene names: 158315461

Gene position: 4343892-4343266 (Counterclockwise)

Preceding gene: 158315462

Following gene: 158315458

Centisome position: 48.36

GC content: 67.94

Gene sequence:

>627_bases
GTGGGTCTCCGCCTGGGCGACACCGCTCCCGACTTCACCGCCACGACCACCGACGGCGAGATCACCTTCCTCGAGTGGAA
GAAGGACTCGTGGGCGGTCTTCTTCAGCCACCCGGCCGACTTCACCCCCGTGTGCACCACCGAGCTGGGCCGCACCGCCG
CGCTGCAGAGCGAGTTCCAGAAGCGGAACACCAAGGCTCTCGCGCTGTCCGTCGACCCGGTCGACCAGCACAACGCCTGG
GCGCCGGACATCGCCGAGGTCGCCGGCAGCGCGCTCAACTTCCCGATCGTGGCCGACCCCGACCACCGCATCGCCGAGCT
GTACGACATGATCCACCCGGGTGAGGGCGACACCTCCACCGTGCGTTCGGTGTTCATCATCGACCCCGCCAACAAGGTGC
GGCTCTCCCTCACCTACCCGAAGTCGGTGGGCCGCAACTTCGACGAGATCATCCGCGTCATCGACGCGCTCCAGGCCACG
GACGCGAACCCCATCGCGACCCCGGCCGACTGGAAGCCCGGCGACCGCGTGATCGTCGCGATCTCGGTCTCGACCGAGGA
CGCCAAGAAGCGGTTCCAGAACGTCGAGGAGACCAAGCCCTACCTGCGCTACGCCGACGCTCCCTGA

Upstream 100 bases:

>100_bases
CGGCGGCCACATGAGGTCTCGCACGTACGGTCGCGGCCGATCGACCGTAGCCTTGGCCTGGCCTGAACAACCACCCGACG
CTACGACGAAAGGACGGCCC

Downstream 100 bases:

>100_bases
TCGATCACGTCACCGGTCTCGTCCCGCCCGATCGTGGGGCGAGGCCGGCCGCCGGCCGCGCGTCCGTCAGGCCGCGCGGC
TCAGCGCGCCGCTGAGGAAG

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MGLRLGDTAPDFTATTTDGEITFLEWKKDSWAVFFSHPADFTPVCTTELGRTAALQSEFQKRNTKALALSVDPVDQHNAW
APDIAEVAGSALNFPIVADPDHRIAELYDMIHPGEGDTSTVRSVFIIDPANKVRLSLTYPKSVGRNFDEIIRVIDALQAT
DANPIATPADWKPGDRVIVAISVSTEDAKKRFQNVEETKPYLRYADAP

Sequences:

>Translated_208_residues
MGLRLGDTAPDFTATTTDGEITFLEWKKDSWAVFFSHPADFTPVCTTELGRTAALQSEFQKRNTKALALSVDPVDQHNAW
APDIAEVAGSALNFPIVADPDHRIAELYDMIHPGEGDTSTVRSVFIIDPANKVRLSLTYPKSVGRNFDEIIRVIDALQAT
DANPIATPADWKPGDRVIVAISVSTEDAKKRFQNVEETKPYLRYADAP
>Mature_207_residues
GLRLGDTAPDFTATTTDGEITFLEWKKDSWAVFFSHPADFTPVCTTELGRTAALQSEFQKRNTKALALSVDPVDQHNAWA
PDIAEVAGSALNFPIVADPDHRIAELYDMIHPGEGDTSTVRSVFIIDPANKVRLSLTYPKSVGRNFDEIIRVIDALQATD
ANPIATPADWKPGDRVIVAISVSTEDAKKRFQNVEETKPYLRYADAP

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=221, Percent_Identity=47.9638009049774, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI4505591, Length=180, Percent_Identity=35.5555555555556, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI32455266, Length=180, Percent_Identity=35.5555555555556, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI32455264, Length=180, Percent_Identity=35.5555555555556, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=35.0515463917526, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI32483377, Length=193, Percent_Identity=30.0518134715026, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI5802974, Length=193, Percent_Identity=30.0518134715026, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1786822, Length=149, Percent_Identity=31.5436241610738, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25153706, Length=194, Percent_Identity=42.7835051546392, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI193204376, Length=192, Percent_Identity=34.8958333333333, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32565831, Length=192, Percent_Identity=34.8958333333333, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17554494, Length=169, Percent_Identity=31.9526627218935, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=49.5283018867925, Blast_Score=212, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6323613, Length=198, Percent_Identity=30.8080808080808, Blast_Score=82, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320661, Length=190, Percent_Identity=30.5263157894737, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24581278, Length=218, Percent_Identity=48.1651376146789, Blast_Score=205, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24652434, Length=199, Percent_Identity=50.251256281407, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17975518, Length=199, Percent_Identity=50.251256281407, Blast_Score=188, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24652436, Length=199, Percent_Identity=50.251256281407, Blast_Score=188, Evalue=3e-48,
Organism=Drosophila melanogaster, GI17738015, Length=194, Percent_Identity=31.4432989690722, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17157991, Length=154, Percent_Identity=32.4675324675325, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24641739, Length=154, Percent_Identity=32.4675324675325, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21357347, Length=192, Percent_Identity=30.2083333333333, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24656348, Length=175, Percent_Identity=32.5714285714286, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17864676, Length=175, Percent_Identity=32.5714285714286, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22917; Mature: 22786

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLRLGDTAPDFTATTTDGEITFLEWKKDSWAVFFSHPADFTPVCTTELGRTAALQSEFQ
CCCCCCCCCCCCEEECCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHCHHHHHHHHHH
KRNTKALALSVDPVDQHNAWAPDIAEVAGSALNFPIVADPDHRIAELYDMIHPGEGDTST
HCCCEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCC
VRSVFIIDPANKVRLSLTYPKSVGRNFDEIIRVIDALQATDANPIATPADWKPGDRVIVA
EEEEEEECCCCEEEEEEECCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
ISVSTEDAKKRFQNVEETKPYLRYADAP
EEECCHHHHHHHHCHHHCCCCEEECCCC
>Mature Secondary Structure 
GLRLGDTAPDFTATTTDGEITFLEWKKDSWAVFFSHPADFTPVCTTELGRTAALQSEFQ
CCCCCCCCCCCEEECCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHCHHHHHHHHHH
KRNTKALALSVDPVDQHNAWAPDIAEVAGSALNFPIVADPDHRIAELYDMIHPGEGDTST
HCCCEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCC
VRSVFIIDPANKVRLSLTYPKSVGRNFDEIIRVIDALQATDANPIATPADWKPGDRVIVA
EEEEEEECCCCEEEEEEECCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
ISVSTEDAKKRFQNVEETKPYLRYADAP
EEECCHHHHHHHHCHHHCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]