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The map label for this gene is lldD [H]

Identifier: 158315310

GI number: 158315310

Start: 4172548

End: 4173339

Strand: Direct

Name: lldD [H]

Synonym: Franean1_3511

Alternate gene names: 158315310

Gene position: 4172548-4173339 (Clockwise)

Preceding gene: 158315309

Following gene: 158315312

Centisome position: 46.45

GC content: 74.75

Gene sequence:

>792_bases
GTGACCCGGTGGGTGGACGAGCTTGAGGAGCGGGCCGCCGCAGCCCTGCCCCGCGATGTGTACGACTACTTCCGGCAGGG
CGCCGGCACCCACCACGCGCTGCACGAGGCAACCCCGGCCTGGGATGCCCTGCGGCTGCACCCGCGGGTCCTACGCGACG
TCACCAGCGTGCGCACCGCCACGACCGTTCTCGGCACCCCCGTCGACACCCCGGTCGTCGGCGACCGGCCCCATCCCGGC
CCCGGATCCGACGCGCCCTGGTACGGCGGTCACCTCCTGCCGACCGCCGCACCGGGGGACGTCGCCGTCGCCACCGACCT
CACCTTCGACGACATCACCTGGCTCCAGGGGATCAGCCGGCTGCCCGTCGTCGTCAAGGGAGTCCTGCGGGCCGACGACG
CGCTGAGCGCCGTGCGGGCAGGGGCCCGCGCGGTCATCGTCAGCAACCACGGCGGTCGCCAGCTCGACGTCGCCGTCCCC
ACGGCCACCGCCCTTCCCGGCATCGCCCGCGCCCTGGTGGGCACCGGCGCCGAGACCTACGTCGACGGCGGTATCCGCAG
CGGCGTCCACGTGCTGGCGGCCCTCGCCCTCGGAGCCCGCGCGGTCCTGCTCGGCCGGCCTGTCCTGTGGGCGCTGGCCA
CCGCCGGGGCTGACAACGTGCACCGACTGCTGAGGACCGTCACCGCCGAGTTGCAGCACGCCATGACCCTCGTCGGTGCC
CGAAACCCGGACGAGATCACCCCGGACCTGGCCGGGCTGGTCGACACCGCCGGCGCTCAGCCACCGGGGTAA

Upstream 100 bases:

>100_bases
TGCCGGCACGGGCGTGTGTGGGGGAGTAACGGGGGGCTGGCGTGGACCAGGAACGTGATCACGCCGGCCGGGCCCGCGCT
CTCACGTCCGGAGCCGGACA

Downstream 100 bases:

>100_bases
CGGACGACTCGACGGCACGATCTACCCAGGATGTCCCGCACCCCCAGCTGGACCCCACAGCGCTGTCCACATTCCGGCTT
GACCTGACTCGTCGCGGTTA

Product: FMN-dependent alpha-hydroxy acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTRWVDELEERAAAALPRDVYDYFRQGAGTHHALHEATPAWDALRLHPRVLRDVTSVRTATTVLGTPVDTPVVGDRPHPG
PGSDAPWYGGHLLPTAAPGDVAVATDLTFDDITWLQGISRLPVVVKGVLRADDALSAVRAGARAVIVSNHGGRQLDVAVP
TATALPGIARALVGTGAETYVDGGIRSGVHVLAALALGARAVLLGRPVLWALATAGADNVHRLLRTVTAELQHAMTLVGA
RNPDEITPDLAGLVDTAGAQPPG

Sequences:

>Translated_263_residues
MTRWVDELEERAAAALPRDVYDYFRQGAGTHHALHEATPAWDALRLHPRVLRDVTSVRTATTVLGTPVDTPVVGDRPHPG
PGSDAPWYGGHLLPTAAPGDVAVATDLTFDDITWLQGISRLPVVVKGVLRADDALSAVRAGARAVIVSNHGGRQLDVAVP
TATALPGIARALVGTGAETYVDGGIRSGVHVLAALALGARAVLLGRPVLWALATAGADNVHRLLRTVTAELQHAMTLVGA
RNPDEITPDLAGLVDTAGAQPPG
>Mature_262_residues
TRWVDELEERAAAALPRDVYDYFRQGAGTHHALHEATPAWDALRLHPRVLRDVTSVRTATTVLGTPVDTPVVGDRPHPGP
GSDAPWYGGHLLPTAAPGDVAVATDLTFDDITWLQGISRLPVVVKGVLRADDALSAVRAGARAVIVSNHGGRQLDVAVPT
ATALPGIARALVGTGAETYVDGGIRSGVHVLAALALGARAVLLGRPVLWALATAGADNVHRLLRTVTAELQHAMTLVGAR
NPDEITPDLAGLVDTAGAQPPG

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=227, Percent_Identity=36.1233480176211, Blast_Score=147, Evalue=7e-36,
Organism=Homo sapiens, GI7705393, Length=227, Percent_Identity=36.1233480176211, Blast_Score=147, Evalue=7e-36,
Organism=Homo sapiens, GI11068137, Length=152, Percent_Identity=45.3947368421053, Blast_Score=128, Evalue=5e-30,
Organism=Escherichia coli, GI1790033, Length=176, Percent_Identity=43.1818181818182, Blast_Score=123, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI193208036, Length=208, Percent_Identity=38.4615384615385, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32566217, Length=112, Percent_Identity=36.6071428571429, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323587, Length=151, Percent_Identity=39.7350993377483, Blast_Score=113, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281363140, Length=144, Percent_Identity=43.75, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI78707190, Length=144, Percent_Identity=43.75, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI78707188, Length=141, Percent_Identity=44.6808510638298, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 27393; Mature: 27262

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRWVDELEERAAAALPRDVYDYFRQGAGTHHALHEATPAWDALRLHPRVLRDVTSVRTA
CCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHCCCCHHHHHHCHHHHHHHHHHHHH
TTVLGTPVDTPVVGDRPHPGPGSDAPWYGGHLLPTAAPGDVAVATDLTFDDITWLQGISR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHH
LPVVVKGVLRADDALSAVRAGARAVIVSNHGGRQLDVAVPTATALPGIARALVGTGAETY
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCCHHHH
VDGGIRSGVHVLAALALGARAVLLGRPVLWALATAGADNVHRLLRTVTAELQHAMTLVGA
HCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
RNPDEITPDLAGLVDTAGAQPPG
CCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRWVDELEERAAAALPRDVYDYFRQGAGTHHALHEATPAWDALRLHPRVLRDVTSVRTA
CHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHCCCCHHHHHHCHHHHHHHHHHHHH
TTVLGTPVDTPVVGDRPHPGPGSDAPWYGGHLLPTAAPGDVAVATDLTFDDITWLQGISR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHH
LPVVVKGVLRADDALSAVRAGARAVIVSNHGGRQLDVAVPTATALPGIARALVGTGAETY
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCCHHHH
VDGGIRSGVHVLAALALGARAVLLGRPVLWALATAGADNVHRLLRTVTAELQHAMTLVGA
HCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
RNPDEITPDLAGLVDTAGAQPPG
CCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA