Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 158315287

GI number: 158315287

Start: 4144326

End: 4145372

Strand: Reverse

Name: fabH [H]

Synonym: Franean1_3487

Alternate gene names: 158315287

Gene position: 4145372-4144326 (Counterclockwise)

Preceding gene: 158315288

Following gene: 158315286

Centisome position: 46.15

GC content: 73.45

Gene sequence:

>1047_bases
GTGCCCGGTCCCGACATCCACGTCCTGTCCGCCGGCTCCGCGCTGCCGGGGCCAGCGGTGGACAACGCCACCCTGGCCCA
GCGGTTCGGCATGGACACGCTCTGGCAGCAGTGGATCGAGGTGTTCATCGGGACCAGGGCCCGGCACCTGGCCCTCGACC
TGGAATCCGGCCAGCTCACCAGCACCCTCGCCGAGCTCGTCGAGCAGGCGGGCCGCCAGGCGCTGGCCGCGGCCGGGCTG
GGGCCCGGCGACATCGACGCGGTGGTGCTCGGCACCGCCACCCCCGACCAGCTCATGCCGGCCACCGTGAACATCGTCGC
CGACCGGCTGGGCATCAACGACGTCCGGACCTACCAGTTGCAGTCCGGGTGCTCCGGTGCCGTGCAGGCGCTGGATGTGG
CGCGCCAGATCCTGCTGGCCGGCAGCGGCCGGCGGGTGCTGGTCCTCGGCGGCGACGTGATCGCCCGGTTCTACGACGTC
ACCGCCGACCTGCGCAAGCTACCGCCCGCGCAGCTCGTCAACTACGTGCTGTTCGGGGACGCGGCCGGCGCGGCCGTGCT
GTCGACCGAGCCGGGGCCCGGCTCGGCGGTGGTGCGGGCGCTGTTCACCCGGCTGGTCGGGCTCGGCCGTCCGCCCGGCG
CGACGCTGGAGTGGTTCGGGCCGACCGACCGCGACAGCACCCGCCCGGCCGCGACCGAGGACTACAAGGCCATCGAGCAG
CACGTGCCGGCGATGACCGGCGAGGTGCTCGAGGAGCTGCTCACCGCCACCGGCTGGAGCCCCGGCGAGGTGGACCTGCT
GCTGCCGCCGCAGCTGTCCGGGCGTATGACCAGGCTGATCACCGAGAAGCTGGCGCTGCCCCGGGCCGGTGAGGTGACCG
TCGTCGACGAGGCCGGCAACTGCGGCAACGCGATCGTCTTCCTCCAGCTGGAGCGGGCGCTGGCCAAGCTCGGCGCGGGT
GAGCGGGCGGTCGGCGTCTCCATCGAGTCCAGCAAGTGGATCAAGGCCGGCTTCGCCCTGCAGGGCGGCGGAGGGGAATC
CCGATGA

Upstream 100 bases:

>100_bases
ACCGGTTTCCGCACCTGGCGGATGACGGGCGTGCGGGCCTCCGCCGAGGCCCGCATCCTGCTGTCCGACTGAGGCCCGCC
GCGCAGGAGAGGAGCACACC

Downstream 100 bases:

>100_bases
CCCGGACCGCACCAGCCCAGACCGCGCCGGCCGAGAACGCGCCGGAGCCGGATCTGCGGGCGCTGCACCGGGCCGACCGG
CTGGGCGACAACGGCCTGGT

Product: beta-ketoacyl-acyl-carrier-protein synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MPGPDIHVLSAGSALPGPAVDNATLAQRFGMDTLWQQWIEVFIGTRARHLALDLESGQLTSTLAELVEQAGRQALAAAGL
GPGDIDAVVLGTATPDQLMPATVNIVADRLGINDVRTYQLQSGCSGAVQALDVARQILLAGSGRRVLVLGGDVIARFYDV
TADLRKLPPAQLVNYVLFGDAAGAAVLSTEPGPGSAVVRALFTRLVGLGRPPGATLEWFGPTDRDSTRPAATEDYKAIEQ
HVPAMTGEVLEELLTATGWSPGEVDLLLPPQLSGRMTRLITEKLALPRAGEVTVVDEAGNCGNAIVFLQLERALAKLGAG
ERAVGVSIESSKWIKAGFALQGGGGESR

Sequences:

>Translated_348_residues
MPGPDIHVLSAGSALPGPAVDNATLAQRFGMDTLWQQWIEVFIGTRARHLALDLESGQLTSTLAELVEQAGRQALAAAGL
GPGDIDAVVLGTATPDQLMPATVNIVADRLGINDVRTYQLQSGCSGAVQALDVARQILLAGSGRRVLVLGGDVIARFYDV
TADLRKLPPAQLVNYVLFGDAAGAAVLSTEPGPGSAVVRALFTRLVGLGRPPGATLEWFGPTDRDSTRPAATEDYKAIEQ
HVPAMTGEVLEELLTATGWSPGEVDLLLPPQLSGRMTRLITEKLALPRAGEVTVVDEAGNCGNAIVFLQLERALAKLGAG
ERAVGVSIESSKWIKAGFALQGGGGESR
>Mature_347_residues
PGPDIHVLSAGSALPGPAVDNATLAQRFGMDTLWQQWIEVFIGTRARHLALDLESGQLTSTLAELVEQAGRQALAAAGLG
PGDIDAVVLGTATPDQLMPATVNIVADRLGINDVRTYQLQSGCSGAVQALDVARQILLAGSGRRVLVLGGDVIARFYDVT
ADLRKLPPAQLVNYVLFGDAAGAAVLSTEPGPGSAVVRALFTRLVGLGRPPGATLEWFGPTDRDSTRPAATEDYKAIEQH
VPAMTGEVLEELLTATGWSPGEVDLLLPPQLSGRMTRLITEKLALPRAGEVTVVDEAGNCGNAIVFLQLERALAKLGAGE
RAVGVSIESSKWIKAGFALQGGGGESR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=311, Percent_Identity=27.6527331189711, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36339; Mature: 36208

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGPDIHVLSAGSALPGPAVDNATLAQRFGMDTLWQQWIEVFIGTRARHLALDLESGQLT
CCCCCEEEEECCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
STLAELVEQAGRQALAAAGLGPGDIDAVVLGTATPDQLMPATVNIVADRLGINDVRTYQL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHCCHHHHHHHHHCCCCHHEEEEE
QSGCSGAVQALDVARQILLAGSGRRVLVLGGDVIARFYDVTADLRKLPPAQLVNYVLFGD
CCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHEECC
AAGAAVLSTEPGPGSAVVRALFTRLVGLGRPPGATLEWFGPTDRDSTRPAATEDYKAIEQ
CCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHH
HVPAMTGEVLEELLTATGWSPGEVDLLLPPQLSGRMTRLITEKLALPRAGEVTVVDEAGN
HCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCC
CGNAIVFLQLERALAKLGAGERAVGVSIESSKWIKAGFALQGGGGESR
CCCEEEEEEHHHHHHHCCCCCCEEEEEECCCCEEEECEEEECCCCCCC
>Mature Secondary Structure 
PGPDIHVLSAGSALPGPAVDNATLAQRFGMDTLWQQWIEVFIGTRARHLALDLESGQLT
CCCCEEEEECCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
STLAELVEQAGRQALAAAGLGPGDIDAVVLGTATPDQLMPATVNIVADRLGINDVRTYQL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHCCHHHHHHHHHCCCCHHEEEEE
QSGCSGAVQALDVARQILLAGSGRRVLVLGGDVIARFYDVTADLRKLPPAQLVNYVLFGD
CCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHEECC
AAGAAVLSTEPGPGSAVVRALFTRLVGLGRPPGATLEWFGPTDRDSTRPAATEDYKAIEQ
CCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHH
HVPAMTGEVLEELLTATGWSPGEVDLLLPPQLSGRMTRLITEKLALPRAGEVTVVDEAGN
HCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCC
CGNAIVFLQLERALAKLGAGERAVGVSIESSKWIKAGFALQGGGGESR
CCCEEEEEEHHHHHHHCCCCCCEEEEEECCCCEEEECEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA