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The map label for this gene is orfB [H]

Identifier: 158315271

GI number: 158315271

Start: 4101039

End: 4104254

Strand: Reverse

Name: orfB [H]

Synonym: Franean1_3471

Alternate gene names: 158315271

Gene position: 4104254-4101039 (Counterclockwise)

Preceding gene: 158315272

Following gene: 158315267

Centisome position: 45.69

GC content: 77.39

Gene sequence:

>3216_bases
ATGACTGACCAGGCTGTGGCGAGCACCGAGGACCGGCTGCGCGACTATCTGCGGCGGGCCACCGCCGACCTGCGCCAGGC
CCGGCGCCGGATCCGGGAGCTGGACGCGCGGGTGCACGAGCCGATCGCGATCGTGGGCATGGGCTGCCGCCTGCCGGGCG
GTGTCGACTCCCCGGAGGCGCTGTGGCGGCTGCTCGACGAGGAGCGGGACGCCATCGCGGACCTGCCCACCGACCGCGGC
TGGGATCCGGAGCGGCTCTACGACCCCGATCCCGACCGGCCGGGCACCACCTACGCCCGCGAGGGTGGGTTCCTCGCCGA
CGCGGGCGGCTTCGACGCGCCGTTCTTCGGCATCGGCCCGCGCGAGGCGACCGCCAGCGACCCGCAGCACCGGCAGCTGC
TCGAGGTCGCCTACGAGACCCTCGAGTACGCCGGGATCGCCCCGGACTCGCTGCACGGCACCCGGACGGGCGTGTACGCC
GGGGTGGTGTCCCAGGCGTACGTGCCGCCGCCGGAGCGGGTGCCAGCCTCGTTCGAGGGCCACCTGATGACGGGGAACGC
GACGAGCGTCGCGTCCGGGCGGGTGGCCTACCACCTCGGGCTGGAGGGACCGGCCCTCACCCTGGACACCGCCTGCTCCT
CGTCGCTGGTAGCGATGCACCTGGCGGCGCGGGCGCTGCAGCGCGGCGAGTGCGACCTGGCGCTCGCCGGCGGGGTGACG
GTGATGGCGACCCCGGTGCTGCTGGTCGAGTTCAGCCGGCAGCGCGGGCTGTCACCGGACGGCCGCTGCAAGGCCTTCGC
TGCGGCGGCGGACGGCACCGGCTTCGCCGAGGGCGTCGGGCTGGTGGCGCTGGAGCGGCTCTCCGACGCCCGCCGGGCCG
GCCGGCGCATCCTGGCGGTGCTGCGCGGCTCGGCGGTGAACTCCGACGGGGCCAGCAACGGGCTGACCGCGCCGAACGGC
GTCAGCCAGGAGCGGGTGATCCGCCAGGCGCTGGCCGACGCGCGGCTGGCCCCGCAGCAGGTCGACGTGGTGGAGGCGCA
CGGGACGGGCACCCGGCTCGGCGACCCGATCGAGGCGCAGGCGCTGCTGGCCACCTACGGGCAGGGCCGGCCGGCCGGCG
AGCCGCTGTGGCTGGGGAGCCTGAAGTCCAACATCGGCCACACCCAGGCCGCCGCCGGCATCGCCGGGGTGATCAAGATG
ATCCTGGCCATGCGGCACGACCGGCTGCCGCGCACCCTGCACGTCGACGAGCCGACGCCGCACGTCGACTGGGCCGGCGG
CGACGTCCAGCTGCTCACCGAGGCCCGCCGGTGGCAGCGCGGCGACCGGCCGCGCCGGGCGGCGGTCTCCTCGTTCGGGA
TCAGCGGCACCAACGCCCACCTCGTCCTGGAGGAGCCGCCCGCGTCCGACGAGCCCGCCGCGGAGACCGAGCCCGGGCTC
GACTCCGACGAGCCGGCCACGGGCGGCCAGGCCGGCCCGGCCGCCGGGACGGGCGACACGCGGCCGCCGGCGGCCGACCC
GGCGGCGGCTCCGTGGGTGCTGTCGGGACGGACCGAGGCGGCGCTGCGGGCCGCGGCCGGCCGGCTGCACGAACGGCTGG
ACGCCGACCCCGGTCTCGACCCGGCCGAGGTCGGGCGGGTGCTGGCCGTCGGGCGCACCGCCCACCCGCACCGGGCGGCC
GTGCTGCCCGGGTCCAACCGCAGGCGGCTGGAGGCGCTCGCCGCGCTGGCGGGCGGCCGGCCCGGCGGGCTGGTCGCGCC
CGGCGGCCCGGGCGGCCGGACGGCGTTCCTGTTCACGGGCCAGGGCAGCCAGCGGCCAGGCATGGGCCGGCACCTCTACG
CCAACCGGCCGGTGTTCGCCGCCGCGCTCGACGAGGTCTTCGCGGCGTTCGAGCCGCTGCTCGACCGGCGGCTGCCCGAC
CTGATGTTCACCGAGCCGGGCACTGACGAGGCGGCGCTGCTCGACCGCACCGAGTACGCCCAGCCGGCCCTGTTCGCGCT
GGAGACGGCGCTGTACCGGCTGCTGGTCGATCTCGGGCCGGAACCGGACCTGGTCGCCGGGCACTCGCTCGGCGGGCTGA
CCGCCGGGCACGTGGCCGGCCTGCTCTCGCTGGCCGACGCCGCCGCGCTCGTCGCCGCCCGCGGCCGCCTCATGCAGGCC
CAGCCCACCGGCGGGCTGATGGCCGCCTGCGAGGCGACCGCGGACGAGATCGAGCCACTGCTCGCCGCGCAGGACGGGCA
GGACGGCCAGGTCTCGCTGGCGGCCGTCAACGGCCCGCGGGCCGTCGTCGTCTCCGGGGACGCGGCGGCGGTCGCCCGGG
TCACGGCGGCCGTCGCCGCCCGCGGTGGGCGGACCCGCACGCTGCGGGTCAGCCACGCCTTCCACTCCGCGCACATGGAC
GGGGCGCTGGCCCCGTTCCGCGAGGTCGTCGCCGGGCTGCGCTTCCAGCCGCCGGTCCTGGACGTCGTCTCCGAGCTGAC
CGGACGGCCGGCGAGCTTCGAGGAGCTGCGCGACCCCGACTACTGGGTGCGCCAGCTGCGCTCGCCGGTGCGCTTCGCCG
ACGCCGTGGCCACGCTGCACGCCGCCGGCGCCACCACCTTCCTCGAGGTCGGCCCGGACGCGGTGCTCACCCCGATGGTG
GCCGACTGCCTCCCGGTGGGCGCCGGCGCGGCGGGCGCGGGCCAGGTGGTGGCGGTGCCCGCCCTGGTCCGGGACCGACC
GGAGGAGCAGGTGCTCGCCACCGCCCTGGTCTGGCGGCATGTGCGCGGCGCGGACGTCCGCTGGGATGCCTGGTTCGGCC
CGGCGGCCGGCCCGCCGCCGCACCTGCCCACCTATCCCTTCGAGCACCGCCGTTACTGGTGGCCCGCCGAGGTCGTCGCC
GCCCCCGCGGGCCCGCGGCCCGTGACGGCCGAGGTGGCTGAGGTCCCCGCGGCCGACCAGGCCGACCAGGCCGACCCGCC
GGTCGCCGCGGACCGTGGGGAGGTGCTGCTCGCCCTGGTCCGTGAGCACGCCGCCGAGGTGCTCGGCCATCCCGATCCGG
ACTCCATCGGGGCGGACGACAACTTCCTGGAGATCGGGTTCTCGTCCTTCACCGCCCTCGAGGTGCGCAACCGGCTGTGC
GAGGCGACCGGCCTGACGCTGCCGGCGGTGCTGCTCTACGACCACCCGACACCGACGGCGGTCGTCCGGTTCCTCGAGGA
GAGCCTGGTCGCCTGA

Upstream 100 bases:

>100_bases
GCTCGACGAGGAGCTGGACGCGCCGTGACCGGATCCGCCGTCCCATACCAGCCAGACAGGTGTGACAGCCAATCAGGTGT
GACAGGGGAGTGCGAGACAG

Downstream 100 bases:

>100_bases
CCTGCCCCGCCCGCGGACGCGTGATCGGCCCCGGCCTTCGAAGGCCGGGGCCGATCAGGAGCTACCAGACGACGGGCAGC
CGGTAGACGCCCTGCACCGA

Product: erythronolide synthase

Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1071; Mature: 1070

Protein sequence:

>1071_residues
MTDQAVASTEDRLRDYLRRATADLRQARRRIRELDARVHEPIAIVGMGCRLPGGVDSPEALWRLLDEERDAIADLPTDRG
WDPERLYDPDPDRPGTTYAREGGFLADAGGFDAPFFGIGPREATASDPQHRQLLEVAYETLEYAGIAPDSLHGTRTGVYA
GVVSQAYVPPPERVPASFEGHLMTGNATSVASGRVAYHLGLEGPALTLDTACSSSLVAMHLAARALQRGECDLALAGGVT
VMATPVLLVEFSRQRGLSPDGRCKAFAAAADGTGFAEGVGLVALERLSDARRAGRRILAVLRGSAVNSDGASNGLTAPNG
VSQERVIRQALADARLAPQQVDVVEAHGTGTRLGDPIEAQALLATYGQGRPAGEPLWLGSLKSNIGHTQAAAGIAGVIKM
ILAMRHDRLPRTLHVDEPTPHVDWAGGDVQLLTEARRWQRGDRPRRAAVSSFGISGTNAHLVLEEPPASDEPAAETEPGL
DSDEPATGGQAGPAAGTGDTRPPAADPAAAPWVLSGRTEAALRAAAGRLHERLDADPGLDPAEVGRVLAVGRTAHPHRAA
VLPGSNRRRLEALAALAGGRPGGLVAPGGPGGRTAFLFTGQGSQRPGMGRHLYANRPVFAAALDEVFAAFEPLLDRRLPD
LMFTEPGTDEAALLDRTEYAQPALFALETALYRLLVDLGPEPDLVAGHSLGGLTAGHVAGLLSLADAAALVAARGRLMQA
QPTGGLMAACEATADEIEPLLAAQDGQDGQVSLAAVNGPRAVVVSGDAAAVARVTAAVAARGGRTRTLRVSHAFHSAHMD
GALAPFREVVAGLRFQPPVLDVVSELTGRPASFEELRDPDYWVRQLRSPVRFADAVATLHAAGATTFLEVGPDAVLTPMV
ADCLPVGAGAAGAGQVVAVPALVRDRPEEQVLATALVWRHVRGADVRWDAWFGPAAGPPPHLPTYPFEHRRYWWPAEVVA
APAGPRPVTAEVAEVPAADQADQADPPVAADRGEVLLALVREHAAEVLGHPDPDSIGADDNFLEIGFSSFTALEVRNRLC
EATGLTLPAVLLYDHPTPTAVVRFLEESLVA

Sequences:

>Translated_1071_residues
MTDQAVASTEDRLRDYLRRATADLRQARRRIRELDARVHEPIAIVGMGCRLPGGVDSPEALWRLLDEERDAIADLPTDRG
WDPERLYDPDPDRPGTTYAREGGFLADAGGFDAPFFGIGPREATASDPQHRQLLEVAYETLEYAGIAPDSLHGTRTGVYA
GVVSQAYVPPPERVPASFEGHLMTGNATSVASGRVAYHLGLEGPALTLDTACSSSLVAMHLAARALQRGECDLALAGGVT
VMATPVLLVEFSRQRGLSPDGRCKAFAAAADGTGFAEGVGLVALERLSDARRAGRRILAVLRGSAVNSDGASNGLTAPNG
VSQERVIRQALADARLAPQQVDVVEAHGTGTRLGDPIEAQALLATYGQGRPAGEPLWLGSLKSNIGHTQAAAGIAGVIKM
ILAMRHDRLPRTLHVDEPTPHVDWAGGDVQLLTEARRWQRGDRPRRAAVSSFGISGTNAHLVLEEPPASDEPAAETEPGL
DSDEPATGGQAGPAAGTGDTRPPAADPAAAPWVLSGRTEAALRAAAGRLHERLDADPGLDPAEVGRVLAVGRTAHPHRAA
VLPGSNRRRLEALAALAGGRPGGLVAPGGPGGRTAFLFTGQGSQRPGMGRHLYANRPVFAAALDEVFAAFEPLLDRRLPD
LMFTEPGTDEAALLDRTEYAQPALFALETALYRLLVDLGPEPDLVAGHSLGGLTAGHVAGLLSLADAAALVAARGRLMQA
QPTGGLMAACEATADEIEPLLAAQDGQDGQVSLAAVNGPRAVVVSGDAAAVARVTAAVAARGGRTRTLRVSHAFHSAHMD
GALAPFREVVAGLRFQPPVLDVVSELTGRPASFEELRDPDYWVRQLRSPVRFADAVATLHAAGATTFLEVGPDAVLTPMV
ADCLPVGAGAAGAGQVVAVPALVRDRPEEQVLATALVWRHVRGADVRWDAWFGPAAGPPPHLPTYPFEHRRYWWPAEVVA
APAGPRPVTAEVAEVPAADQADQADPPVAADRGEVLLALVREHAAEVLGHPDPDSIGADDNFLEIGFSSFTALEVRNRLC
EATGLTLPAVLLYDHPTPTAVVRFLEESLVA
>Mature_1070_residues
TDQAVASTEDRLRDYLRRATADLRQARRRIRELDARVHEPIAIVGMGCRLPGGVDSPEALWRLLDEERDAIADLPTDRGW
DPERLYDPDPDRPGTTYAREGGFLADAGGFDAPFFGIGPREATASDPQHRQLLEVAYETLEYAGIAPDSLHGTRTGVYAG
VVSQAYVPPPERVPASFEGHLMTGNATSVASGRVAYHLGLEGPALTLDTACSSSLVAMHLAARALQRGECDLALAGGVTV
MATPVLLVEFSRQRGLSPDGRCKAFAAAADGTGFAEGVGLVALERLSDARRAGRRILAVLRGSAVNSDGASNGLTAPNGV
SQERVIRQALADARLAPQQVDVVEAHGTGTRLGDPIEAQALLATYGQGRPAGEPLWLGSLKSNIGHTQAAAGIAGVIKMI
LAMRHDRLPRTLHVDEPTPHVDWAGGDVQLLTEARRWQRGDRPRRAAVSSFGISGTNAHLVLEEPPASDEPAAETEPGLD
SDEPATGGQAGPAAGTGDTRPPAADPAAAPWVLSGRTEAALRAAAGRLHERLDADPGLDPAEVGRVLAVGRTAHPHRAAV
LPGSNRRRLEALAALAGGRPGGLVAPGGPGGRTAFLFTGQGSQRPGMGRHLYANRPVFAAALDEVFAAFEPLLDRRLPDL
MFTEPGTDEAALLDRTEYAQPALFALETALYRLLVDLGPEPDLVAGHSLGGLTAGHVAGLLSLADAAALVAARGRLMQAQ
PTGGLMAACEATADEIEPLLAAQDGQDGQVSLAAVNGPRAVVVSGDAAAVARVTAAVAARGGRTRTLRVSHAFHSAHMDG
ALAPFREVVAGLRFQPPVLDVVSELTGRPASFEELRDPDYWVRQLRSPVRFADAVATLHAAGATTFLEVGPDAVLTPMVA
DCLPVGAGAAGAGQVVAVPALVRDRPEEQVLATALVWRHVRGADVRWDAWFGPAAGPPPHLPTYPFEHRRYWWPAEVVAA
PAGPRPVTAEVAEVPAADQADQADPPVAADRGEVLLALVREHAAEVLGHPDPDSIGADDNFLEIGFSSFTALEVRNRLCE
ATGLTLPAVLLYDHPTPTAVVRFLEESLVA

Specific function: May be involved in the biosynthesis of the oleandomycin lactone ring [H]

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=929, Percent_Identity=29.6017222820237, Blast_Score=294, Evalue=3e-79,
Organism=Homo sapiens, GI8923559, Length=279, Percent_Identity=30.1075268817204, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI310129082, Length=98, Percent_Identity=38.7755102040816, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI310109937, Length=98, Percent_Identity=38.7755102040816, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI239744023, Length=98, Percent_Identity=38.7755102040816, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1787337, Length=284, Percent_Identity=31.3380281690141, Blast_Score=109, Evalue=8e-25,
Organism=Escherichia coli, GI1787334, Length=291, Percent_Identity=35.7388316151203, Blast_Score=103, Evalue=8e-23,
Organism=Escherichia coli, GI1788663, Length=292, Percent_Identity=27.3972602739726, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI212642053, Length=801, Percent_Identity=27.5905118601748, Blast_Score=264, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17550940, Length=470, Percent_Identity=30.8510638297872, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71983541, Length=433, Percent_Identity=29.3302540415704, Blast_Score=125, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71983535, Length=270, Percent_Identity=31.1111111111111, Blast_Score=122, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320904, Length=280, Percent_Identity=29.2857142857143, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24581345, Length=850, Percent_Identity=29.8823529411765, Blast_Score=268, Evalue=2e-71,
Organism=Drosophila melanogaster, GI19920632, Length=871, Percent_Identity=27.5545350172216, Blast_Score=261, Evalue=2e-69,
Organism=Drosophila melanogaster, GI221330659, Length=871, Percent_Identity=27.5545350172216, Blast_Score=261, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24644341, Length=281, Percent_Identity=30.9608540925267, Blast_Score=117, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR000794
- InterPro:   IPR002198
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR013968
- InterPro:   IPR020806
- InterPro:   IPR020802
- InterPro:   IPR015083
- InterPro:   IPR006162
- InterPro:   IPR001031
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF00106 adh_short; PF08990 Docking; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 112427; Mature: 112295

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQAVASTEDRLRDYLRRATADLRQARRRIRELDARVHEPIAIVGMGCRLPGGVDSPEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHH
LWRLLDEERDAIADLPTDRGWDPERLYDPDPDRPGTTYAREGGFLADAGGFDAPFFGIGP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEECCCCCCCCCCCCCC
REATASDPQHRQLLEVAYETLEYAGIAPDSLHGTRTGVYAGVVSQAYVPPPERVPASFEG
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCC
HLMTGNATSVASGRVAYHLGLEGPALTLDTACSSSLVAMHLAARALQRGECDLALAGGVT
EEEECCCCCCCCCCEEEEECCCCCCEEEHHHHCHHHHHHHHHHHHHHCCCCCEEEECCCH
VMATPVLLVEFSRQRGLSPDGRCKAFAAAADGTGFAEGVGLVALERLSDARRAGRRILAV
HHHHHHHHEEEHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRGSAVNSDGASNGLTAPNGVSQERVIRQALADARLAPQQVDVVEAHGTGTRLGDPIEAQ
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHH
ALLATYGQGRPAGEPLWLGSLKSNIGHTQAAAGIAGVIKMILAMRHDRLPRTLHVDEPTP
HHHHHCCCCCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
HVDWAGGDVQLLTEARRWQRGDRPRRAAVSSFGISGTNAHLVLEEPPASDEPAAETEPGL
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCC
DSDEPATGGQAGPAAGTGDTRPPAADPAAAPWVLSGRTEAALRAAAGRLHERLDADPGLD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCC
PAEVGRVLAVGRTAHPHRAAVLPGSNRRRLEALAALAGGRPGGLVAPGGPGGRTAFLFTG
HHHHCCEEEECCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEEC
QGSQRPGMGRHLYANRPVFAAALDEVFAAFEPLLDRRLPDLMFTEPGTDEAALLDRTEYA
CCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHCCHHHC
QPALFALETALYRLLVDLGPEPDLVAGHSLGGLTAGHVAGLLSLADAAALVAARGRLMQA
CHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
QPTGGLMAACEATADEIEPLLAAQDGQDGQVSLAAVNGPRAVVVSGDAAAVARVTAAVAA
CCCCCCHHHHHHCHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHH
RGGRTRTLRVSHAFHSAHMDGALAPFREVVAGLRFQPPVLDVVSELTGRPASFEELRDPD
CCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHCCHH
YWVRQLRSPVRFADAVATLHAAGATTFLEVGPDAVLTPMVADCLPVGAGAAGAGQVVAVP
HHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEEH
ALVRDRPEEQVLATALVWRHVRGADVRWDAWFGPAAGPPPHLPTYPFEHRRYWWPAEVVA
HHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCHHHEE
APAGPRPVTAEVAEVPAADQADQADPPVAADRGEVLLALVREHAAEVLGHPDPDSIGADD
CCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NFLEIGFSSFTALEVRNRLCEATGLTLPAVLLYDHPTPTAVVRFLEESLVA
CEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDQAVASTEDRLRDYLRRATADLRQARRRIRELDARVHEPIAIVGMGCRLPGGVDSPEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHH
LWRLLDEERDAIADLPTDRGWDPERLYDPDPDRPGTTYAREGGFLADAGGFDAPFFGIGP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEECCCCCCCCCCCCCC
REATASDPQHRQLLEVAYETLEYAGIAPDSLHGTRTGVYAGVVSQAYVPPPERVPASFEG
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCC
HLMTGNATSVASGRVAYHLGLEGPALTLDTACSSSLVAMHLAARALQRGECDLALAGGVT
EEEECCCCCCCCCCEEEEECCCCCCEEEHHHHCHHHHHHHHHHHHHHCCCCCEEEECCCH
VMATPVLLVEFSRQRGLSPDGRCKAFAAAADGTGFAEGVGLVALERLSDARRAGRRILAV
HHHHHHHHEEEHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRGSAVNSDGASNGLTAPNGVSQERVIRQALADARLAPQQVDVVEAHGTGTRLGDPIEAQ
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHH
ALLATYGQGRPAGEPLWLGSLKSNIGHTQAAAGIAGVIKMILAMRHDRLPRTLHVDEPTP
HHHHHCCCCCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
HVDWAGGDVQLLTEARRWQRGDRPRRAAVSSFGISGTNAHLVLEEPPASDEPAAETEPGL
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCC
DSDEPATGGQAGPAAGTGDTRPPAADPAAAPWVLSGRTEAALRAAAGRLHERLDADPGLD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCC
PAEVGRVLAVGRTAHPHRAAVLPGSNRRRLEALAALAGGRPGGLVAPGGPGGRTAFLFTG
HHHHCCEEEECCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEEC
QGSQRPGMGRHLYANRPVFAAALDEVFAAFEPLLDRRLPDLMFTEPGTDEAALLDRTEYA
CCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHCCHHHC
QPALFALETALYRLLVDLGPEPDLVAGHSLGGLTAGHVAGLLSLADAAALVAARGRLMQA
CHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
QPTGGLMAACEATADEIEPLLAAQDGQDGQVSLAAVNGPRAVVVSGDAAAVARVTAAVAA
CCCCCCHHHHHHCHHHHHHHHHCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHH
RGGRTRTLRVSHAFHSAHMDGALAPFREVVAGLRFQPPVLDVVSELTGRPASFEELRDPD
CCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHCCHH
YWVRQLRSPVRFADAVATLHAAGATTFLEVGPDAVLTPMVADCLPVGAGAAGAGQVVAVP
HHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEEH
ALVRDRPEEQVLATALVWRHVRGADVRWDAWFGPAAGPPPHLPTYPFEHRRYWWPAEVVA
HHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCHHHEE
APAGPRPVTAEVAEVPAADQADQADPPVAADRGEVLLALVREHAAEVLGHPDPDSIGADD
CCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NFLEIGFSSFTALEVRNRLCEATGLTLPAVLLYDHPTPTAVVRFLEESLVA
CEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: None [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} [C]

Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]

Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8107683 [H]