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The map label for this gene is tfdA [H]

Identifier: 158314787

GI number: 158314787

Start: 3497527

End: 3498372

Strand: Direct

Name: tfdA [H]

Synonym: Franean1_2971

Alternate gene names: 158314787

Gene position: 3497527-3498372 (Clockwise)

Preceding gene: 158314786

Following gene: 158314789

Centisome position: 38.94

GC content: 68.44

Gene sequence:

>846_bases
GTGACGACGACCATCTCCTGTGAGCCTCTTGCCGCCACGGTCGGCGCCGAGGTGAGTGGCGTCGACGCCGGCCAGCTCGC
TCACGACGACACCGTCGCCACCGCCGTCCTCGAGGCGCTCGAACAGTACGGCGTGCTCGTTTTCCGCGGCCTGCACCTCG
CCCCAGAGACTCAGGTCGCCTTCGGTCGGCGCCTCGGCGAGATTGACTACGAGCAGGGCCACCACCCCGTGTCCGGGATC
TACCGGGTCACCCTCGACACGTCGAAGAACACCTCGGCCGACTACCTGAGGGCCACGTTCGAGTGGCACATGGACGGCTG
CACCCCGCTCCACGGAGAGCCGCCGCAGAAGGCCACCATTCTCAGCGCCAAAGCGGTGGCAACCAGCGGCGGAGAGACCG
AGTTCGCCAATACCTACGCCGCCTACGAGGCGCTCAGCGACGGGGAGAAGGAAGAGTTCGGCTCGCTGCGCGTCGTGCAC
ACCATGGAAGCGTCCCAGCGCCGGGTCACGCCCGACCCGACCCCTGAACAGCTCCAGCGATGGCGGAACCGTCCGACGTC
GACCCACCCCCTGGTGTGGACGCATCGCACCGGCCGGCGGTCGCTCGTGATCGGTGCCAATGCCAGCCATGTCGTCGGGA
TGGGCCTCAACGAGGGGCCGAGCCTGCTACAGGAACTGCTCGACCGGGCGACGGCGCCCGACAGGGTCTACCGCCATCAG
TGGTCGGTGGGCGACACCGTCATCTGGGACAACACCGGCGTCGTGCACCGCGCGGCACCCTACGACTCGCACTCGCCCCG
GGAGATGCTGCGTACGACCGTGTTCGGGGATGAGCCGATCCGTTGA

Upstream 100 bases:

>100_bases
ACTCGCTCGTCATGGTCGCGCTGCCTGTCGAGGTCTGGCACCAGCCGAGAGTGATCGACGCCGGGACCGCCTACTTCGAC
CGTTACCTGGAGCCCGTGCC

Downstream 100 bases:

>100_bases
AGCCACTCGTGTCGCTTCTTCGGGGGCGGCTAGCTGGCCTGACCGGCGACGATCTTGTCGTCGGCCGGGCGGCGGTCTCC
TTCGAGGGCGCGGATCTCGC

Product: taurine catabolism dioxygenase TauD/TfdA

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: 2,4-D dioxygenase [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTTTISCEPLAATVGAEVSGVDAGQLAHDDTVATAVLEALEQYGVLVFRGLHLAPETQVAFGRRLGEIDYEQGHHPVSGI
YRVTLDTSKNTSADYLRATFEWHMDGCTPLHGEPPQKATILSAKAVATSGGETEFANTYAAYEALSDGEKEEFGSLRVVH
TMEASQRRVTPDPTPEQLQRWRNRPTSTHPLVWTHRTGRRSLVIGANASHVVGMGLNEGPSLLQELLDRATAPDRVYRHQ
WSVGDTVIWDNTGVVHRAAPYDSHSPREMLRTTVFGDEPIR

Sequences:

>Translated_281_residues
MTTTISCEPLAATVGAEVSGVDAGQLAHDDTVATAVLEALEQYGVLVFRGLHLAPETQVAFGRRLGEIDYEQGHHPVSGI
YRVTLDTSKNTSADYLRATFEWHMDGCTPLHGEPPQKATILSAKAVATSGGETEFANTYAAYEALSDGEKEEFGSLRVVH
TMEASQRRVTPDPTPEQLQRWRNRPTSTHPLVWTHRTGRRSLVIGANASHVVGMGLNEGPSLLQELLDRATAPDRVYRHQ
WSVGDTVIWDNTGVVHRAAPYDSHSPREMLRTTVFGDEPIR
>Mature_280_residues
TTTISCEPLAATVGAEVSGVDAGQLAHDDTVATAVLEALEQYGVLVFRGLHLAPETQVAFGRRLGEIDYEQGHHPVSGIY
RVTLDTSKNTSADYLRATFEWHMDGCTPLHGEPPQKATILSAKAVATSGGETEFANTYAAYEALSDGEKEEFGSLRVVHT
MEASQRRVTPDPTPEQLQRWRNRPTSTHPLVWTHRTGRRSLVIGANASHVVGMGLNEGPSLLQELLDRATAPDRVYRHQW
SVGDTVIWDNTGVVHRAAPYDSHSPREMLRTTVFGDEPIR

Specific function: Involved in degradation of the herbicide 2,4- dichlorophenoxyacetic acid (2,4-D). Is also able to degrade 2- methyl-4-chlorophenoxyacetic acid and 3-chlorobenzoic acid [H]

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=287, Percent_Identity=29.2682926829268, Blast_Score=109, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322971, Length=297, Percent_Identity=26.9360269360269, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 30850; Mature: 30718

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTISCEPLAATVGAEVSGVDAGQLAHDDTVATAVLEALEQYGVLVFRGLHLAPETQVA
CCCEECCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCHHHH
FGRRLGEIDYEQGHHPVSGIYRVTLDTSKNTSADYLRATFEWHMDGCTPLHGEPPQKATI
HHHHHCCCCHHCCCCCCCEEEEEEEECCCCCCHHHHEEEEEEECCCCCCCCCCCCCCEEE
LSAKAVATSGGETEFANTYAAYEALSDGEKEEFGSLRVVHTMEASQRRVTPDPTPEQLQR
EEHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHCCEEEEEECCCCCCCCCCCCCHHHHHH
WRNRPTSTHPLVWTHRTGRRSLVIGANASHVVGMGLNEGPSLLQELLDRATAPDRVYRHQ
HHCCCCCCCCEEEEECCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCCCCHHHHHC
WSVGDTVIWDNTGVVHRAAPYDSHSPREMLRTTVFGDEPIR
CCCCCEEEECCCCCEEECCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTTISCEPLAATVGAEVSGVDAGQLAHDDTVATAVLEALEQYGVLVFRGLHLAPETQVA
CCEECCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCHHHH
FGRRLGEIDYEQGHHPVSGIYRVTLDTSKNTSADYLRATFEWHMDGCTPLHGEPPQKATI
HHHHHCCCCHHCCCCCCCEEEEEEEECCCCCCHHHHEEEEEEECCCCCCCCCCCCCCEEE
LSAKAVATSGGETEFANTYAAYEALSDGEKEEFGSLRVVHTMEASQRRVTPDPTPEQLQR
EEHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHCCEEEEEECCCCCCCCCCCCCHHHHHH
WRNRPTSTHPLVWTHRTGRRSLVIGANASHVVGMGLNEGPSLLQELLDRATAPDRVYRHQ
HHCCCCCCCCEEEEECCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCCCCHHHHHC
WSVGDTVIWDNTGVVHRAAPYDSHSPREMLRTTVFGDEPIR
CCCCCEEEECCCCCEEECCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8779585 [H]