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The map label for this gene is alsR [H]

Identifier: 158314155

GI number: 158314155

Start: 2772342

End: 2773271

Strand: Direct

Name: alsR [H]

Synonym: Franean1_2323

Alternate gene names: 158314155

Gene position: 2772342-2773271 (Clockwise)

Preceding gene: 158314151

Following gene: 158314156

Centisome position: 30.87

GC content: 70.75

Gene sequence:

>930_bases
ATGGTTATGGATGTGCATGTGCGGGACCTCCGTTACTTCGTGGCGGTCGCCGAGGAACAGAGCTTCACCCGGGCGGCGAG
TCAGCGGCTGTTCATCTCGCAGCCGGCGCTGAGCAAGCAGATCCGCCAGCTGGAGCAGTCATTGCGGACCGTCCTGTTCG
ATCGGGACCGGCGGACGGTCCGGCTGACTCCGGCCGGAGAGGCCCTGCTGCCCTACGCCCGGCAGCTCACCGAGGACTGG
GAGGCGGCGCTGCTCGCGGTGTCGGAGGCGTCGGCCCAGGCCGGGACGACAGTGAGGGTCGGCTTTCAGACGCGGATCGG
TCGCGGGCTCATCCCAGCCATCACCGCGCGGATGCGACAGCGGCTTCCCGGCTGGAAGCTGATGTTCCGCCAGGTCTCCT
GGGCCGACCCCACGGTCGGCCTGGCCCAGGGCGAGGTGGACATCGCGATCGCCTGGCTGCCGGTACCCGACACCGGCGCG
CTTTCCTGGCGGGTCGTGGCGCGGGAGGATGTCTGGGTAGCACTCGCGCCCCGACACCGCCTGGCCAGTCGGCCCATAGT
GCCTTTCGCCGATCTCGCCGACGAGCCCTTCGTCGCGCTGCCGAGGACGGCCGGCGCCCAGCGGGACTTCTGGCTCGGGG
CGGCGGCCCGGCGGTCCCCGGCCGTCATCGCGGGGGAGGCCGAGACCGCCGAGGAGTCGTTCGAAGCGGTCGCCTCCGGG
ACAGGGATCACCCTGCTTTCCGCTGGCAACGCCGAGATCTACCACCGCGACGACGTCGTCTGCCGGCCGGTCAGCGGACT
GCCGCCCAGCGAACTGGCCGTCGTCTGGCGAACGGTCGACAACCGACCGTTCGTCGACGTCTTCGCCGACATCTGCCGTG
CCTGCTCCAGCCCCGCGGCCGAGGCTGGTAAGTGCGACCCGTCACTGTGA

Upstream 100 bases:

>100_bases
GGCGTCCCACTCGTGGACCTCACCCGGCCGGGCGCGTCCTGTCCGCCAGACCACCGTGCCCGGCTCCTCCGGGTCGGTCC
AAGACCCGTTGTTATAACCA

Downstream 100 bases:

>100_bases
TCGGCTCCGTTGACGCCGCCCGGGGACAGGAATCCGCCTGCTGCGCACGAACCGCCCGCCCGGGTGCCACCCGCTACGGG
CGGAGAGCCGACATCACCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MVMDVHVRDLRYFVAVAEEQSFTRAASQRLFISQPALSKQIRQLEQSLRTVLFDRDRRTVRLTPAGEALLPYARQLTEDW
EAALLAVSEASAQAGTTVRVGFQTRIGRGLIPAITARMRQRLPGWKLMFRQVSWADPTVGLAQGEVDIAIAWLPVPDTGA
LSWRVVAREDVWVALAPRHRLASRPIVPFADLADEPFVALPRTAGAQRDFWLGAAARRSPAVIAGEAETAEESFEAVASG
TGITLLSAGNAEIYHRDDVVCRPVSGLPPSELAVVWRTVDNRPFVDVFADICRACSSPAAEAGKCDPSL

Sequences:

>Translated_309_residues
MVMDVHVRDLRYFVAVAEEQSFTRAASQRLFISQPALSKQIRQLEQSLRTVLFDRDRRTVRLTPAGEALLPYARQLTEDW
EAALLAVSEASAQAGTTVRVGFQTRIGRGLIPAITARMRQRLPGWKLMFRQVSWADPTVGLAQGEVDIAIAWLPVPDTGA
LSWRVVAREDVWVALAPRHRLASRPIVPFADLADEPFVALPRTAGAQRDFWLGAAARRSPAVIAGEAETAEESFEAVASG
TGITLLSAGNAEIYHRDDVVCRPVSGLPPSELAVVWRTVDNRPFVDVFADICRACSSPAAEAGKCDPSL
>Mature_309_residues
MVMDVHVRDLRYFVAVAEEQSFTRAASQRLFISQPALSKQIRQLEQSLRTVLFDRDRRTVRLTPAGEALLPYARQLTEDW
EAALLAVSEASAQAGTTVRVGFQTRIGRGLIPAITARMRQRLPGWKLMFRQVSWADPTVGLAQGEVDIAIAWLPVPDTGA
LSWRVVAREDVWVALAPRHRLASRPIVPFADLADEPFVALPRTAGAQRDFWLGAAARRSPAVIAGEAETAEESFEAVASG
TGITLLSAGNAEIYHRDDVVCRPVSGLPPSELAVVWRTVDNRPFVDVFADICRACSSPAAEAGKCDPSL

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=297, Percent_Identity=32.3232323232323, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787879, Length=253, Percent_Identity=34.7826086956522, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790399, Length=252, Percent_Identity=32.1428571428571, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI2367136, Length=280, Percent_Identity=31.7857142857143, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788887, Length=294, Percent_Identity=30.2721088435374, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787601, Length=195, Percent_Identity=30.2564102564103, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87081904, Length=179, Percent_Identity=31.2849162011173, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=30.5220883534137, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI145693105, Length=203, Percent_Identity=25.1231527093596, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788297, Length=257, Percent_Identity=27.6264591439689, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790262, Length=266, Percent_Identity=27.8195488721804, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994962, Length=89, Percent_Identity=44.9438202247191, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790208, Length=169, Percent_Identity=30.1775147928994, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787530, Length=193, Percent_Identity=24.3523316062176, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787589, Length=94, Percent_Identity=40.4255319148936, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33810; Mature: 33810

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMDVHVRDLRYFVAVAEEQSFTRAASQRLFISQPALSKQIRQLEQSLRTVLFDRDRRTV
CEEEEEHHHHEEEEHHHCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEE
RLTPAGEALLPYARQLTEDWEAALLAVSEASAQAGTTVRVGFQTRIGRGLIPAITARMRQ
EECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHH
RLPGWKLMFRQVSWADPTVGLAQGEVDIAIAWLPVPDTGALSWRVVAREDVWVALAPRHR
HCCCHHHHHHHHCCCCCCCEEECCCEEEEEEEEECCCCCCEEEEEEEECCEEEEECCCHH
LASRPIVPFADLADEPFVALPRTAGAQRDFWLGAAARRSPAVIAGEAETAEESFEAVASG
HCCCCCCCHHHCCCCCCEECCCCCCCCCCEEECCCCCCCCCEEECCCHHHHHHHHHHHCC
TGITLLSAGNAEIYHRDDVVCRPVSGLPPSELAVVWRTVDNRPFVDVFADICRACSSPAA
CCEEEEECCCCEEEECCCCEEECCCCCCHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCC
EAGKCDPSL
CCCCCCCCC
>Mature Secondary Structure
MVMDVHVRDLRYFVAVAEEQSFTRAASQRLFISQPALSKQIRQLEQSLRTVLFDRDRRTV
CEEEEEHHHHEEEEHHHCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEE
RLTPAGEALLPYARQLTEDWEAALLAVSEASAQAGTTVRVGFQTRIGRGLIPAITARMRQ
EECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHH
RLPGWKLMFRQVSWADPTVGLAQGEVDIAIAWLPVPDTGALSWRVVAREDVWVALAPRHR
HCCCHHHHHHHHCCCCCCCEEECCCEEEEEEEEECCCCCCEEEEEEEECCEEEEECCCHH
LASRPIVPFADLADEPFVALPRTAGAQRDFWLGAAARRSPAVIAGEAETAEESFEAVASG
HCCCCCCCHHHCCCCCCEECCCCCCCCCCEEECCCCCCCCCEEECCCHHHHHHHHHHHCC
TGITLLSAGNAEIYHRDDVVCRPVSGLPPSELAVVWRTVDNRPFVDVFADICRACSSPAA
CCEEEEECCCCEEEECCCCEEECCCCCCHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCC
EAGKCDPSL
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]