Click here to switch to the map view.

The map label for this gene is ptrB [C]

Identifier: 158314127

GI number: 158314127

Start: 2743192

End: 2745522

Strand: Direct

Name: ptrB [C]

Synonym: Franean1_2294

Alternate gene names: 158314127

Gene position: 2743192-2745522 (Clockwise)

Preceding gene: 158314126

Following gene: 158314129

Centisome position: 30.54

GC content: 77.82

Gene sequence:

>2331_bases
ATGATCCGTCCGGTCGAGTCGGCGCTCACCGGCGTCCCGTCCCGGACCGCCGCGGCGCGGTCTGAGACCACCGCGGCACC
GGCTGGCGCCCTGCCGGCCGGTACCGTGCCGGTCCAACCGGTGGACTCGCCGGTCCTGGGAGCGGTCGAGCCGCCGCTCC
CGGCACCGCGGGACCTGGTGGACGAGTGGGCCACGCCGCCGAGCGTGCGCGGGCCCTCACCCGGCCCGGACGGCTCGATC
GCCTTCGTCGGGGACGCCACCGGGCGCCCGGCCCTGTGGGTCCGCGCGGCCGACGGGACGGAGCGGGTCCTCGACACCGG
CCCGGCGCACGTCCGGTCGGCGCTGTGGTCCCCGGACGGCGCCTGGATCGCGATCACCGTGGCCCCGGGCGGCGGGGAGC
ACACCGAGGTCCACCTTGTCCGCCCGGACGGCAGGGTCCGCCCGGACGGCAGGGTCCGCCCGGACGGCACGGCGGCGCAC
CGGCTGGCCGGTGGCGTCCGGCCCGGCACGGCGGGAGCCGTGGAGGCGTGCGCGGCCACGGTCTCCCGGTGGGCGGCGGG
CGGCCGGCTGCTCGTGGTCACCGAGTCGGCCCGCTCCGGGCTGACCCACGCGGTCGCCGTCGACCCGGCCGGCCACCGCC
GCCACCTCGCGGTGGGGCTGGCCCTGCAGGTCTGCGCCGTCCACGAGACCGCCGACCGGTGGCTGCTGCTCCTGCGGGAG
GGCCCGCGGGGCGCCCGGCGCGTGCTGGTGGCCCGGGTGGACGCGCCCGACCCGCTGGCACCGGCCGCCGCCCCGCTCGA
GGCGTTCCCGCTCAACGACGAGATGGCCGGCGGAGTGGCCGGCAGCGGGGGGACCGTCGGAGGGGTGGCGACCGAGGCGT
TCGAGGTCGCGGGCGGCACCACCACGGCCGTCTCAGGCACCTTCGCCGCGGACGCCTCGCGTGCCCTGCTCGCCTGCGAC
CTGGGCCGCGAGCGGCCGGGCCTGCTCGAGGTGCCCCTGGACCCGCACGGCCGGCCGGGGCCGACCCGACTGCTGGCCGG
CCGGGACGACGCGGACCTGGAGCGCTTCCTCCTCCTCGACCCGGCCACGGCCGTGCTCGGCTGGAACGTCGGCGGGCGCA
CCGAGCTCGCCGTCCACAGCCTGGACGACGGGACGTCGCGGGCCCTGCCGCCGCTGCCGCGCGAGGTGGTCACCGGCCTG
CTCCCCGGGCCCGGCGGGGCGAGCCTGCTCCTGGCGCTGGACGGCTCCACCGCCCCCAGCGAGGTGTGGACCTGCGACCT
GACCGGCACCGCGGCGGGCATTCCGCCCGGCACCGCGTCGGACGCCCCGGACGGCACCTCGGCGGGCACCTCGGACAGCG
GCGTGCCGGCCTACCGCTGCCTGGTCTCGCACACGCCGACGGCGTACCCCACCGTCGAGATCACGGCCGTGGCCGCGAGC
GGGACGCACACCGCGGGCCCGGGCCCGTGCCCGGCGGGGGCGCCCGAGGTGCCCGGCGGGACGGAGGACGTGGGCTACCG
GTTCGTCCGCCCGATCGCGCGCCGGTTCCTCGCGCACGACGGGCTGGAGCTCACCGGCTGGTGGTACCGCCCGCGGGTGG
CCCCGGGGCCGGTGCCCACCCTGCTCTACTTCCATGGCGGCCCGGAGGCGCAGGAGCGCCCCGTCCTCAACCCGCTCTTC
CACGCGCTGCTCGCCCGCGGCATCGCCGTGTTCGCGCCGAACGTGCGCGGCTCCACCGGGTTCGGTCGCTCGTTCGAGGA
GGCCGACCACCTGGCCGGCCGCTTCGCCGGCATCGCCGACGTCGCGAGTGCCGTGACGCACCTGGTCACCGAGGGCCTGG
CCGCGCCGGGCCACATCGGCGTGGCCGGCCGGTCCTACGGCGGGTACCTGACGCTGGCCGCGTTGGTCTGCCACCCCGAG
CTGTTCGCCGTCGGTGTCGACGTGTGCGGGATGGTCGATCTGGAGACCTTCTACCGGCACACCGAACCGTGGATCGCCGC
ACCGGCGGTCACCAAGTACGGCGACCCGGCGACCGACCGCGACCTGCTACGGGCTCTGTCGCCGTTGCACCGGATGGATG
CGCTCGCGGCCCCGCTGCTGGTCGTGCACGGGGCCAACGACACCAACGTCCCCGTGTGTGAGGCCGAGCAGACTGTCGCC
GCGGCCCGGGCCCGCGGGATCCCGTGCGAGTACCTGCTCTTCGAGGGCGAGGGCCACGAGGTCGCCGAGCGCGCGAACCG
GCTGGTGTTCGTCCGCGCCGTGGTGGAGTTCGTCGCGGCGTGCCTGACCGGCGCGCAGGCGCCGGCGGACACCCTCGGCG
AGGCCGTCTGA

Upstream 100 bases:

>100_bases
GATGCTCGCCGACCCGAACTCGAACCGTACGACGCTCGGGGCGAACGCGCTCTGGCAGGCCGCCCTGCTCGAGATGTGGC
TGCAGACACAGGGGGTGTGA

Downstream 100 bases:

>100_bases
CCGATCGCGCCGGCGCCGCACGGTCGGTGCTCGGTGGTTGCGGTCGGTCAGCGCCGCACAGCCGGCGCCGCGCGTCGGGC
GCTGGGCGGTCAGCGGCGGG

Product: peptidase S9 prolyl oligopeptidase

Products: NA

Alternate protein names: AARE; Acyl-peptide hydrolase; APH; Acylaminoacyl-peptidase [H]

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MIRPVESALTGVPSRTAAARSETTAAPAGALPAGTVPVQPVDSPVLGAVEPPLPAPRDLVDEWATPPSVRGPSPGPDGSI
AFVGDATGRPALWVRAADGTERVLDTGPAHVRSALWSPDGAWIAITVAPGGGEHTEVHLVRPDGRVRPDGRVRPDGTAAH
RLAGGVRPGTAGAVEACAATVSRWAAGGRLLVVTESARSGLTHAVAVDPAGHRRHLAVGLALQVCAVHETADRWLLLLRE
GPRGARRVLVARVDAPDPLAPAAAPLEAFPLNDEMAGGVAGSGGTVGGVATEAFEVAGGTTTAVSGTFAADASRALLACD
LGRERPGLLEVPLDPHGRPGPTRLLAGRDDADLERFLLLDPATAVLGWNVGGRTELAVHSLDDGTSRALPPLPREVVTGL
LPGPGGASLLLALDGSTAPSEVWTCDLTGTAAGIPPGTASDAPDGTSAGTSDSGVPAYRCLVSHTPTAYPTVEITAVAAS
GTHTAGPGPCPAGAPEVPGGTEDVGYRFVRPIARRFLAHDGLELTGWWYRPRVAPGPVPTLLYFHGGPEAQERPVLNPLF
HALLARGIAVFAPNVRGSTGFGRSFEEADHLAGRFAGIADVASAVTHLVTEGLAAPGHIGVAGRSYGGYLTLAALVCHPE
LFAVGVDVCGMVDLETFYRHTEPWIAAPAVTKYGDPATDRDLLRALSPLHRMDALAAPLLVVHGANDTNVPVCEAEQTVA
AARARGIPCEYLLFEGEGHEVAERANRLVFVRAVVEFVAACLTGAQAPADTLGEAV

Sequences:

>Translated_776_residues
MIRPVESALTGVPSRTAAARSETTAAPAGALPAGTVPVQPVDSPVLGAVEPPLPAPRDLVDEWATPPSVRGPSPGPDGSI
AFVGDATGRPALWVRAADGTERVLDTGPAHVRSALWSPDGAWIAITVAPGGGEHTEVHLVRPDGRVRPDGRVRPDGTAAH
RLAGGVRPGTAGAVEACAATVSRWAAGGRLLVVTESARSGLTHAVAVDPAGHRRHLAVGLALQVCAVHETADRWLLLLRE
GPRGARRVLVARVDAPDPLAPAAAPLEAFPLNDEMAGGVAGSGGTVGGVATEAFEVAGGTTTAVSGTFAADASRALLACD
LGRERPGLLEVPLDPHGRPGPTRLLAGRDDADLERFLLLDPATAVLGWNVGGRTELAVHSLDDGTSRALPPLPREVVTGL
LPGPGGASLLLALDGSTAPSEVWTCDLTGTAAGIPPGTASDAPDGTSAGTSDSGVPAYRCLVSHTPTAYPTVEITAVAAS
GTHTAGPGPCPAGAPEVPGGTEDVGYRFVRPIARRFLAHDGLELTGWWYRPRVAPGPVPTLLYFHGGPEAQERPVLNPLF
HALLARGIAVFAPNVRGSTGFGRSFEEADHLAGRFAGIADVASAVTHLVTEGLAAPGHIGVAGRSYGGYLTLAALVCHPE
LFAVGVDVCGMVDLETFYRHTEPWIAAPAVTKYGDPATDRDLLRALSPLHRMDALAAPLLVVHGANDTNVPVCEAEQTVA
AARARGIPCEYLLFEGEGHEVAERANRLVFVRAVVEFVAACLTGAQAPADTLGEAV
>Mature_776_residues
MIRPVESALTGVPSRTAAARSETTAAPAGALPAGTVPVQPVDSPVLGAVEPPLPAPRDLVDEWATPPSVRGPSPGPDGSI
AFVGDATGRPALWVRAADGTERVLDTGPAHVRSALWSPDGAWIAITVAPGGGEHTEVHLVRPDGRVRPDGRVRPDGTAAH
RLAGGVRPGTAGAVEACAATVSRWAAGGRLLVVTESARSGLTHAVAVDPAGHRRHLAVGLALQVCAVHETADRWLLLLRE
GPRGARRVLVARVDAPDPLAPAAAPLEAFPLNDEMAGGVAGSGGTVGGVATEAFEVAGGTTTAVSGTFAADASRALLACD
LGRERPGLLEVPLDPHGRPGPTRLLAGRDDADLERFLLLDPATAVLGWNVGGRTELAVHSLDDGTSRALPPLPREVVTGL
LPGPGGASLLLALDGSTAPSEVWTCDLTGTAAGIPPGTASDAPDGTSAGTSDSGVPAYRCLVSHTPTAYPTVEITAVAAS
GTHTAGPGPCPAGAPEVPGGTEDVGYRFVRPIARRFLAHDGLELTGWWYRPRVAPGPVPTLLYFHGGPEAQERPVLNPLF
HALLARGIAVFAPNVRGSTGFGRSFEEADHLAGRFAGIADVASAVTHLVTEGLAAPGHIGVAGRSYGGYLTLAALVCHPE
LFAVGVDVCGMVDLETFYRHTEPWIAAPAVTKYGDPATDRDLLRALSPLHRMDALAAPLLVVHGANDTNVPVCEAEQTVA
AARARGIPCEYLLFEGEGHEVAERANRLVFVRAVVEFVAACLTGAQAPADTLGEAV

Specific function: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N- acetylated amino acid and a peptide with a free N-terminus [H]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9C family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=217, Percent_Identity=26.7281105990783, Blast_Score=67, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25144540, Length=238, Percent_Identity=33.6134453781513, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25144537, Length=238, Percent_Identity=33.6134453781513, Blast_Score=126, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17552908, Length=204, Percent_Identity=32.3529411764706, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25144543, Length=114, Percent_Identity=38.5964912280702, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45551969, Length=286, Percent_Identity=27.972027972028, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI45550825, Length=286, Percent_Identity=26.9230769230769, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45553511, Length=286, Percent_Identity=26.9230769230769, Blast_Score=79, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR001375
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: =3.4.19.1 [H]

Molecular weight: Translated: 79532; Mature: 79532

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00708 PRO_ENDOPEP_SER ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPVESALTGVPSRTAAARSETTAAPAGALPAGTVPVQPVDSPVLGAVEPPLPAPRDLV
CCCCHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
DEWATPPSVRGPSPGPDGSIAFVGDATGRPALWVRAADGTERVLDTGPAHVRSALWSPDG
HHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHCCCHHHHHHHHCCCCC
AWIAITVAPGGGEHTEVHLVRPDGRVRPDGRVRPDGTAAHRLAGGVRPGTAGAVEACAAT
CEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHH
VSRWAAGGRLLVVTESARSGLTHAVAVDPAGHRRHLAVGLALQVCAVHETADRWLLLLRE
HHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCEEEEEEEC
GPRGARRVLVARVDAPDPLAPAAAPLEAFPLNDEMAGGVAGSGGTVGGVATEAFEVAGGT
CCCCCEEEEEEEECCCCCCCCCCCCCEECCCCCHHCCCCCCCCCCCCCHHHHHHHHCCCC
TTAVSGTFAADASRALLACDLGRERPGLLEVPLDPHGRPGPTRLLAGRDDADLERFLLLD
EEEECCEECCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCEEEEEC
PATAVLGWNVGGRTELAVHSLDDGTSRALPPLPREVVTGLLPGPGGASLLLALDGSTAPS
CCHHEEECCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCC
EVWTCDLTGTAAGIPPGTASDAPDGTSAGTSDSGVPAYRCLVSHTPTAYPTVEITAVAAS
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEEEC
GTHTAGPGPCPAGAPEVPGGTEDVGYRFVRPIARRFLAHDGLELTGWWYRPRVAPGPVPT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCE
LLYFHGGPEAQERPVLNPLFHALLARGIAVFAPNVRGSTGFGRSFEEADHLAGRFAGIAD
EEEECCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VASAVTHLVTEGLAAPGHIGVAGRSYGGYLTLAALVCHPELFAVGVDVCGMVDLETFYRH
HHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCHHEEEHHHHCCEEEHHHHHHC
TEPWIAAPAVTKYGDPATDRDLLRALSPLHRMDALAAPLLVVHGANDTNVPVCEAEQTVA
CCCCEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEECCHHHHH
AARARGIPCEYLLFEGEGHEVAERANRLVFVRAVVEFVAACLTGAQAPADTLGEAV
HHHHCCCCEEEEEEECCCHHHHHHCCCEEHHHHHHHHHHHHHCCCCCCHHHHCCCC
>Mature Secondary Structure
MIRPVESALTGVPSRTAAARSETTAAPAGALPAGTVPVQPVDSPVLGAVEPPLPAPRDLV
CCCCHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
DEWATPPSVRGPSPGPDGSIAFVGDATGRPALWVRAADGTERVLDTGPAHVRSALWSPDG
HHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHCCCHHHHHHHHCCCCC
AWIAITVAPGGGEHTEVHLVRPDGRVRPDGRVRPDGTAAHRLAGGVRPGTAGAVEACAAT
CEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHH
VSRWAAGGRLLVVTESARSGLTHAVAVDPAGHRRHLAVGLALQVCAVHETADRWLLLLRE
HHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCEEEEEEEC
GPRGARRVLVARVDAPDPLAPAAAPLEAFPLNDEMAGGVAGSGGTVGGVATEAFEVAGGT
CCCCCEEEEEEEECCCCCCCCCCCCCEECCCCCHHCCCCCCCCCCCCCHHHHHHHHCCCC
TTAVSGTFAADASRALLACDLGRERPGLLEVPLDPHGRPGPTRLLAGRDDADLERFLLLD
EEEECCEECCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCEEEEEC
PATAVLGWNVGGRTELAVHSLDDGTSRALPPLPREVVTGLLPGPGGASLLLALDGSTAPS
CCHHEEECCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCC
EVWTCDLTGTAAGIPPGTASDAPDGTSAGTSDSGVPAYRCLVSHTPTAYPTVEITAVAAS
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEEEC
GTHTAGPGPCPAGAPEVPGGTEDVGYRFVRPIARRFLAHDGLELTGWWYRPRVAPGPVPT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCE
LLYFHGGPEAQERPVLNPLFHALLARGIAVFAPNVRGSTGFGRSFEEADHLAGRFAGIAD
EEEECCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VASAVTHLVTEGLAAPGHIGVAGRSYGGYLTLAALVCHPELFAVGVDVCGMVDLETFYRH
HHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCHHEEEHHHHCCEEEHHHHHHC
TEPWIAAPAVTKYGDPATDRDLLRALSPLHRMDALAAPLLVVHGANDTNVPVCEAEQTVA
CCCCEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEECCHHHHH
AARARGIPCEYLLFEGEGHEVAERANRLVFVRAVVEFVAACLTGAQAPADTLGEAV
HHHHCCCCEEEEEEECCCHHHHHHCCCEEHHHHHHHHHHHHHCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10382966; 12037315 [H]