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The map label for this gene is bcsA [H]

Identifier: 158314090

GI number: 158314090

Start: 2697476

End: 2699329

Strand: Direct

Name: bcsA [H]

Synonym: Franean1_2257

Alternate gene names: 158314090

Gene position: 2697476-2699329 (Clockwise)

Preceding gene: 158314088

Following gene: 158314094

Centisome position: 30.03

GC content: 66.83

Gene sequence:

>1854_bases
GTGAGTGGTCCGGTGCGCGAGGCGTACGTTCCGGAGGATGTGGCGGGTGGCGTCGGGGCGCTGACCGTCCCCCTGCGGTA
CCAGAAGTTCACGCCGGGCCTCCGGGAGCCGATGCGGGACCATTCCGGGAACCGGGTCCGGTCGACGGCCGTGATGAGCC
GGTGGCAGGAACTGCAGTACTGGCTGATCACGGTGGGGTGGCTGGCTGCCACGGTGTTCTTCTGGCGGTGGTGGCTACGC
GCCGACAACGTCGGCTCGATTGTGTTGTTCGTGCTGATGTCGGTGTCCTTCTTCTACGTCGGTGCCTTCCTGGCGGGGAT
GTATCTGATCTTTGTCGGGCACATGCGCCGGCCCGTTCCCATTCCGGTGCGCCAGGCGGAGATCTCGGCGCCGATCCGGC
GGGTTGCCGTCATCAGCCTCACCGTCCCCGGCTCGGAGTCCCTCGAGATCGTCCGTCGCCAGCTGGTGGCGATGAGCAGG
ATCAGATATCCACACGACAGCTGGATACTCGTCGACAAGGTCTCCTCACCGGAGATCGAGGAGCTCGCCCGGTCGGTAGG
TGTCCGGTACTTCTCGCGGCACGACGAGGCCCGCTGGGGAAGGGAGGGGGTGGCGGGCTGGAACCGCCGGTTCCCGCCGT
TCAAACGCAAGACCAAGGCCGGCAACGTCAACAGCTGGCTGGACGCCCACGGCCACGAGTACAGCCACTTCACCCAGCTC
GACATCGATCACATACCGAACCCCGACTACCTGGACCGGGTGCTCGGCTACTTCGCGGACCCCAAGGTCAAGTGGGTGCA
GGCGCCGAGTGTGTACGGGAACTTCGAACACTGGACCGCCCGGGGCGCGGCCGAGCAGGAACTGGGTCTGCAGGGACCGC
TTCAGATGGGGTTCTTCGGGTTCTCGCGGACGCCCTTCATCATCGGGAGTCACTGCACCTACGACACGGCCGGCATCCTC
GAGATCGGCGGGTTCCAGCCGACCAGGGCGGAGGACCACCTCGACACCGTCTGCCTGGCGGCGCGCGGATATCAGGGCGT
CTTCGTCCCGGACGTCATCGCGACCGGTGACGGGCCCGAGACGTTCGAGACCTATCTGTCGCAGCAGTTCGCGTGGGCGT
ACTCGATGATCGAGGTCCTCCTGCGGCACACGCCCCGACTCCTCCGCAGGTACGGACCGCGGCAGGCCGTCCAGTTTCTC
TTCGCCCAGACCTGGTACACCCTCTGGTCGCTGTCGATGCTGATCCTCTTCGCGCTGCCGCTCCTCGCGCTCTGCCTGAA
CCAGGCCATCGCGAAGGTCCACTATCTGGATTTCCTCGCCCACAGTGTTCCGCTGAGCGTCACCTCGCTGCTGATCTGGT
GGTGGAGCCGGCCGTGGCACGTGCCGGCCGGTATACGGCTGACCTGGCGCGGGATCGTCCTGCACGCCGCCCGGTGGATC
GTGGTCCTCTCCGCGCTCGTCCAGGTCGTCCTCAGAGTCAAGAAGCCATACATGATCACGAAGAAGGGAGTGGGGGGTGG
GGCCGGAACCGTCTCACTGCGACCCATGGCTCCCTACATCGCGATGGTGGTTGTCCCGCTCGCGGCCTGCTGGACCTATC
TCACCGTCCATCACGCGGGCGGGAGATCGGGCTATCTCCTGTTCGCCCTGCAGGACTCCCTGACCTTCCTGCTGGTCCTG
TCCGTCGTGATCCTGCAGGAGGTCCGGCTGTCCGGAGACGGGGGTACGCCGCTCGCCGTTCGGCTGCGCCGCGCGGCGGC
GCCGTTGGCGGCGACGGGACTGCTCACGGCCGCGACGGTCGCCACCGCGATCGCCTCATGGCACCCGATCTGGGAGGCGG
TCTCCTCTGCGTGA

Upstream 100 bases:

>100_bases
GGCGCTCTTCTCTCCGTACGCCTTGTGCGCGGGGACGCATGGCGACTGTTTTCTTCGCCGCTCGTCGAAACGAGCGCGCG
GATTCTTTTGGGGGAGACCG

Downstream 100 bases:

>100_bases
GGTCGTGCGGGCGGTGTGTCCACACAGAGTGAGTCCGAGTGGACGGCCGTGCCGCATCCCCTGGCAGACCGACGACGCGA
ACAACGTGCTGGCGATCAGC

Product: putative transmembrane cellulose synthase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MSGPVREAYVPEDVAGGVGALTVPLRYQKFTPGLREPMRDHSGNRVRSTAVMSRWQELQYWLITVGWLAATVFFWRWWLR
ADNVGSIVLFVLMSVSFFYVGAFLAGMYLIFVGHMRRPVPIPVRQAEISAPIRRVAVISLTVPGSESLEIVRRQLVAMSR
IRYPHDSWILVDKVSSPEIEELARSVGVRYFSRHDEARWGREGVAGWNRRFPPFKRKTKAGNVNSWLDAHGHEYSHFTQL
DIDHIPNPDYLDRVLGYFADPKVKWVQAPSVYGNFEHWTARGAAEQELGLQGPLQMGFFGFSRTPFIIGSHCTYDTAGIL
EIGGFQPTRAEDHLDTVCLAARGYQGVFVPDVIATGDGPETFETYLSQQFAWAYSMIEVLLRHTPRLLRRYGPRQAVQFL
FAQTWYTLWSLSMLILFALPLLALCLNQAIAKVHYLDFLAHSVPLSVTSLLIWWWSRPWHVPAGIRLTWRGIVLHAARWI
VVLSALVQVVLRVKKPYMITKKGVGGGAGTVSLRPMAPYIAMVVVPLAACWTYLTVHHAGGRSGYLLFALQDSLTFLLVL
SVVILQEVRLSGDGGTPLAVRLRRAAAPLAATGLLTAATVATAIASWHPIWEAVSSA

Sequences:

>Translated_617_residues
MSGPVREAYVPEDVAGGVGALTVPLRYQKFTPGLREPMRDHSGNRVRSTAVMSRWQELQYWLITVGWLAATVFFWRWWLR
ADNVGSIVLFVLMSVSFFYVGAFLAGMYLIFVGHMRRPVPIPVRQAEISAPIRRVAVISLTVPGSESLEIVRRQLVAMSR
IRYPHDSWILVDKVSSPEIEELARSVGVRYFSRHDEARWGREGVAGWNRRFPPFKRKTKAGNVNSWLDAHGHEYSHFTQL
DIDHIPNPDYLDRVLGYFADPKVKWVQAPSVYGNFEHWTARGAAEQELGLQGPLQMGFFGFSRTPFIIGSHCTYDTAGIL
EIGGFQPTRAEDHLDTVCLAARGYQGVFVPDVIATGDGPETFETYLSQQFAWAYSMIEVLLRHTPRLLRRYGPRQAVQFL
FAQTWYTLWSLSMLILFALPLLALCLNQAIAKVHYLDFLAHSVPLSVTSLLIWWWSRPWHVPAGIRLTWRGIVLHAARWI
VVLSALVQVVLRVKKPYMITKKGVGGGAGTVSLRPMAPYIAMVVVPLAACWTYLTVHHAGGRSGYLLFALQDSLTFLLVL
SVVILQEVRLSGDGGTPLAVRLRRAAAPLAATGLLTAATVATAIASWHPIWEAVSSA
>Mature_616_residues
SGPVREAYVPEDVAGGVGALTVPLRYQKFTPGLREPMRDHSGNRVRSTAVMSRWQELQYWLITVGWLAATVFFWRWWLRA
DNVGSIVLFVLMSVSFFYVGAFLAGMYLIFVGHMRRPVPIPVRQAEISAPIRRVAVISLTVPGSESLEIVRRQLVAMSRI
RYPHDSWILVDKVSSPEIEELARSVGVRYFSRHDEARWGREGVAGWNRRFPPFKRKTKAGNVNSWLDAHGHEYSHFTQLD
IDHIPNPDYLDRVLGYFADPKVKWVQAPSVYGNFEHWTARGAAEQELGLQGPLQMGFFGFSRTPFIIGSHCTYDTAGILE
IGGFQPTRAEDHLDTVCLAARGYQGVFVPDVIATGDGPETFETYLSQQFAWAYSMIEVLLRHTPRLLRRYGPRQAVQFLF
AQTWYTLWSLSMLILFALPLLALCLNQAIAKVHYLDFLAHSVPLSVTSLLIWWWSRPWHVPAGIRLTWRGIVLHAARWIV
VLSALVQVVLRVKKPYMITKKGVGGGAGTVSLRPMAPYIAMVVVPLAACWTYLTVHHAGGRSGYLLFALQDSLTFLLVLS
VVILQEVRLSGDGGTPLAVRLRRAAAPLAATGLLTAATVATAIASWHPIWEAVSSA

Specific function: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection [H]

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

Organism=Escherichia coli, GI87082284, Length=430, Percent_Identity=25.1162790697674, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003919
- InterPro:   IPR005150
- InterPro:   IPR001173
- InterPro:   IPR009875 [H]

Pfam domain/function: PF03552 Cellulose_synt; PF00535 Glycos_transf_2; PF07238 PilZ [H]

EC number: =2.4.1.12 [H]

Molecular weight: Translated: 69114; Mature: 68983

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPVREAYVPEDVAGGVGALTVPLRYQKFTPGLREPMRDHSGNRVRSTAVMSRWQELQY
CCCCCCCCCCCHHHCCCCCEEEECEEHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
WLITVGWLAATVFFWRWWLRADNVGSIVLFVLMSVSFFYVGAFLAGMYLIFVGHMRRPVP
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IPVRQAEISAPIRRVAVISLTVPGSESLEIVRRQLVAMSRIRYPHDSWILVDKVSSPEIE
CCCHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHH
ELARSVGVRYFSRHDEARWGREGVAGWNRRFPPFKRKTKAGNVNSWLDAHGHEYSHFTQL
HHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHCCCCCCCCEEEE
DIDHIPNPDYLDRVLGYFADPKVKWVQAPSVYGNFEHWTARGAAEQELGLQGPLQMGFFG
ECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCCCHHHCCCCCCHHHCEEC
FSRTPFIIGSHCTYDTAGILEIGGFQPTRAEDHLDTVCLAARGYQGVFVPDVIATGDGPE
CCCCCEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCHH
TFETYLSQQFAWAYSMIEVLLRHTPRLLRRYGPRQAVQFLFAQTWYTLWSLSMLILFALP
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALCLNQAIAKVHYLDFLAHSVPLSVTSLLIWWWSRPWHVPAGIRLTWRGIVLHAARWI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEHHHHHHHHHHHH
VVLSALVQVVLRVKKPYMITKKGVGGGAGTVSLRPMAPYIAMVVVPLAACWTYLTVHHAG
HHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC
GRSGYLLFALQDSLTFLLVLSVVILQEVRLSGDGGTPLAVRLRRAAAPLAATGLLTAATV
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
ATAIASWHPIWEAVSSA
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGPVREAYVPEDVAGGVGALTVPLRYQKFTPGLREPMRDHSGNRVRSTAVMSRWQELQY
CCCCCCCCCCHHHCCCCCEEEECEEHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
WLITVGWLAATVFFWRWWLRADNVGSIVLFVLMSVSFFYVGAFLAGMYLIFVGHMRRPVP
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IPVRQAEISAPIRRVAVISLTVPGSESLEIVRRQLVAMSRIRYPHDSWILVDKVSSPEIE
CCCHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHH
ELARSVGVRYFSRHDEARWGREGVAGWNRRFPPFKRKTKAGNVNSWLDAHGHEYSHFTQL
HHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHCCCCCCCCEEEE
DIDHIPNPDYLDRVLGYFADPKVKWVQAPSVYGNFEHWTARGAAEQELGLQGPLQMGFFG
ECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCCCHHHCCCCCCHHHCEEC
FSRTPFIIGSHCTYDTAGILEIGGFQPTRAEDHLDTVCLAARGYQGVFVPDVIATGDGPE
CCCCCEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCHH
TFETYLSQQFAWAYSMIEVLLRHTPRLLRRYGPRQAVQFLFAQTWYTLWSLSMLILFALP
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALCLNQAIAKVHYLDFLAHSVPLSVTSLLIWWWSRPWHVPAGIRLTWRGIVLHAARWI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEHHHHHHHHHHHH
VVLSALVQVVLRVKKPYMITKKGVGGGAGTVSLRPMAPYIAMVVVPLAACWTYLTVHHAG
HHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC
GRSGYLLFALQDSLTFLLVLSVVILQEVRLSGDGGTPLAVRLRRAAAPLAATGLLTAATV
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
ATAIASWHPIWEAVSSA
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]