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The map label for this gene is era [H]

Identifier: 158313950

GI number: 158313950

Start: 2542134

End: 2543066

Strand: Direct

Name: era [H]

Synonym: Franean1_2116

Alternate gene names: 158313950

Gene position: 2542134-2543066 (Clockwise)

Preceding gene: 158313949

Following gene: 158313952

Centisome position: 28.3

GC content: 72.56

Gene sequence:

>933_bases
GTGGACATCGAGCTCGCCGACCCGGCGACGGACTTCCGGTCGGGGTTCGCCTGCCTGGTGGGGCGGCCCAACGCGGGTAA
GTCGACGCTGACGAACGCCCTGGTGGGGACGAAGGTGGCGATCACCTCCGGGCGGCCGCAGACGACCCGCCACGCCATCC
GGGGCATCATCAACCGCCCCGACGCGCAGCTCATCCTGGTCGACACCCCGGGGTTGCACCGTCCGCGCACCCTGCTCGGC
CAGCGGCTCAACGACGTCGTCCGCACGACGCTGTCCGAGGTCGACGTGATCGGCTTCTGCATGCCCGCCGACGAGCCCCT
CGGCCGCGGCGACCGCTTCATCGCCGACGAGCTGGGCCGGATGGCGGGGCGCACCCCGGTGGTGGCGATCCTGACCAAGG
TCGACGCGGTCGGCGACCCGGACCGCGTCGGCGCCCGGCTGCTCGAGGTCTCCGGGCTCGGCGACTTCGCCGACATCGTG
CCGGTGAGCGCGGTGTCGTCCTTCCAGGTCGGCACGCTGGCCGACGTGCTCGTCTCCCGCCTGCCCGAGGGCCCGCGGCT
CTACCCCGACGGGGAGCTGACCGACGAGCCCGAGCAGGTCATGGTCGCCGAGCTGATCCGCGAGGCGGCGCTGGAGGGGG
TGCGTGACGAGCTGCCGCACTCACTGGCCGTGGTGGTCGAGGAGATGATCCCGCGGGAGAACCGCCCGGAGGACAGGCCG
CTGCTCGACGTCCACGTGAACGTGTACGTGGAGCGGCCGAGCCAGAAGGCGATCGTCATCGGCGCCGGCGGCTCCCGGCT
GCGCGACGTCGGCACCCGGGCCCGGACGCAGATCGAGGCGCTGCTGGGCACCCCGATCTACCTGGACCTGCACGTCAAGG
TTGCCAAGGACTGGCAGCGGGACCCGAAGCAGCTGCGCCGGCTGGGCTTCTGA

Upstream 100 bases:

>100_bases
CCGCCGGCGACGACCTGGCGATGCTCGCCGAGTTCGGCGCCGGGGTGCCCGTCTACCTCGCCGGTCCCGACGGCGTCGCA
CGCAGCCGGGTGACGAGCTA

Downstream 100 bases:

>100_bases
GCGTCACGACGCGGAGCACCATGGCCGTGGGTGTCACGACGGTGTCGGCAGCCGGCGCCGCAGGCGGTCCCACCAGCGCC
GGGCCGGCGACCGCTCGTCG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDIELADPATDFRSGFACLVGRPNAGKSTLTNALVGTKVAITSGRPQTTRHAIRGIINRPDAQLILVDTPGLHRPRTLLG
QRLNDVVRTTLSEVDVIGFCMPADEPLGRGDRFIADELGRMAGRTPVVAILTKVDAVGDPDRVGARLLEVSGLGDFADIV
PVSAVSSFQVGTLADVLVSRLPEGPRLYPDGELTDEPEQVMVAELIREAALEGVRDELPHSLAVVVEEMIPRENRPEDRP
LLDVHVNVYVERPSQKAIVIGAGGSRLRDVGTRARTQIEALLGTPIYLDLHVKVAKDWQRDPKQLRRLGF

Sequences:

>Translated_310_residues
MDIELADPATDFRSGFACLVGRPNAGKSTLTNALVGTKVAITSGRPQTTRHAIRGIINRPDAQLILVDTPGLHRPRTLLG
QRLNDVVRTTLSEVDVIGFCMPADEPLGRGDRFIADELGRMAGRTPVVAILTKVDAVGDPDRVGARLLEVSGLGDFADIV
PVSAVSSFQVGTLADVLVSRLPEGPRLYPDGELTDEPEQVMVAELIREAALEGVRDELPHSLAVVVEEMIPRENRPEDRP
LLDVHVNVYVERPSQKAIVIGAGGSRLRDVGTRARTQIEALLGTPIYLDLHVKVAKDWQRDPKQLRRLGF
>Mature_310_residues
MDIELADPATDFRSGFACLVGRPNAGKSTLTNALVGTKVAITSGRPQTTRHAIRGIINRPDAQLILVDTPGLHRPRTLLG
QRLNDVVRTTLSEVDVIGFCMPADEPLGRGDRFIADELGRMAGRTPVVAILTKVDAVGDPDRVGARLLEVSGLGDFADIV
PVSAVSSFQVGTLADVLVSRLPEGPRLYPDGELTDEPEQVMVAELIREAALEGVRDELPHSLAVVVEEMIPRENRPEDRP
LLDVHVNVYVERPSQKAIVIGAGGSRLRDVGTRARTQIEALLGTPIYLDLHVKVAKDWQRDPKQLRRLGF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=301, Percent_Identity=34.8837209302326, Blast_Score=184, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24646434, Length=323, Percent_Identity=24.1486068111455, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33711; Mature: 33711

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIELADPATDFRSGFACLVGRPNAGKSTLTNALVGTKVAITSGRPQTTRHAIRGIINRP
CCCCCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCC
DAQLILVDTPGLHRPRTLLGQRLNDVVRTTLSEVDVIGFCMPADEPLGRGDRFIADELGR
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHH
MAGRTPVVAILTKVDAVGDPDRVGARLLEVSGLGDFADIVPVSAVSSFQVGTLADVLVSR
HCCCCHHHHHHHHHCCCCCHHHHHHHHEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LPEGPRLYPDGELTDEPEQVMVAELIREAALEGVRDELPHSLAVVVEEMIPRENRPEDRP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC
LLDVHVNVYVERPSQKAIVIGAGGSRLRDVGTRARTQIEALLGTPIYLDLHVKVAKDWQR
EEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHCC
DPKQLRRLGF
CHHHHHHCCC
>Mature Secondary Structure
MDIELADPATDFRSGFACLVGRPNAGKSTLTNALVGTKVAITSGRPQTTRHAIRGIINRP
CCCCCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCC
DAQLILVDTPGLHRPRTLLGQRLNDVVRTTLSEVDVIGFCMPADEPLGRGDRFIADELGR
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHH
MAGRTPVVAILTKVDAVGDPDRVGARLLEVSGLGDFADIVPVSAVSSFQVGTLADVLVSR
HCCCCHHHHHHHHHCCCCCHHHHHHHHEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LPEGPRLYPDGELTDEPEQVMVAELIREAALEGVRDELPHSLAVVVEEMIPRENRPEDRP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC
LLDVHVNVYVERPSQKAIVIGAGGSRLRDVGTRARTQIEALLGTPIYLDLHVKVAKDWQR
EEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHCC
DPKQLRRLGF
CHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]