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The map label for this gene is kstR2 [H]

Identifier: 158313723

GI number: 158313723

Start: 2265355

End: 2265963

Strand: Direct

Name: kstR2 [H]

Synonym: Franean1_1887

Alternate gene names: 158313723

Gene position: 2265355-2265963 (Clockwise)

Preceding gene: 158313718

Following gene: 158313724

Centisome position: 25.22

GC content: 72.09

Gene sequence:

>609_bases
GTGGGAAAGGACGTGGCGGGAAAGGACGTGGTCCGGCCCAGTTCGGTGCGGTCCGCGCAGATCCGCGCCGCCGCGCTCGA
CCTGTTCACGCGCTCCGGCTACGAGGCCACCACGATGGCCGACCTCGGTGCCGCCGTGGGCATGCGCGGACCCAGCCTGT
ACAAGCACGTCGCGTCCAAGCAGGACGTCCTCGAGCAGATCATGACCGGCACGATGGAGGCGCTCCTGGCCGCGCACCGG
ACGGCCGTCGCGACCACGGCGGACCCGGTGGAACGGCTGCGGCGCGCCACGGAGGCGCATGTCCGGTACCATGCGCGGCA
CCGGCTGGAGGCGTTCGTCGGGAACCGCGAGATCCGCAGCCTCACCCAGCCCAACCGCGAGCGTGTGCTGGGCCTGCGCG
CGGAGTACGAGCGGTGCTTCCGGGACCTCATCGAGGCCGGCCTGCGGGCGGGGCGGTTCCAGGTGGAGTCCGCGAGGCTG
GCCTCGTACGCGATCCTCGACCTGGGGATGGGCGTCGCGGTGTGGTTCCGCGATGACGGCGAGCTGACCGAGGACGCCGT
GGTCTGGCAGTTCAGCCAGTTCGCCCTGCGCATCGTGGGCGCGGCGTAG

Upstream 100 bases:

>100_bases
TAGACACGGCTTTGCGTTGGCCGCAAGTGATCCTGACTATGATGCGAGGTGACGGTGGCCAGGCTTGGCTATCACCTGTT
AGCGATCGGGGAGGGACGTG

Downstream 100 bases:

>100_bases
GCGCGGCCGGCTTCGGCCAGCGATCAGGTGGGCGGGTTCCAGCGGTAGCGTCGGCGCGGTGATTTCCCTCCCGGACCGGC
CGGCGGTGCCTGACCCCACG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MGKDVAGKDVVRPSSVRSAQIRAAALDLFTRSGYEATTMADLGAAVGMRGPSLYKHVASKQDVLEQIMTGTMEALLAAHR
TAVATTADPVERLRRATEAHVRYHARHRLEAFVGNREIRSLTQPNRERVLGLRAEYERCFRDLIEAGLRAGRFQVESARL
ASYAILDLGMGVAVWFRDDGELTEDAVVWQFSQFALRIVGAA

Sequences:

>Translated_202_residues
MGKDVAGKDVVRPSSVRSAQIRAAALDLFTRSGYEATTMADLGAAVGMRGPSLYKHVASKQDVLEQIMTGTMEALLAAHR
TAVATTADPVERLRRATEAHVRYHARHRLEAFVGNREIRSLTQPNRERVLGLRAEYERCFRDLIEAGLRAGRFQVESARL
ASYAILDLGMGVAVWFRDDGELTEDAVVWQFSQFALRIVGAA
>Mature_201_residues
GKDVAGKDVVRPSSVRSAQIRAAALDLFTRSGYEATTMADLGAAVGMRGPSLYKHVASKQDVLEQIMTGTMEALLAAHRT
AVATTADPVERLRRATEAHVRYHARHRLEAFVGNREIRSLTQPNRERVLGLRAEYERCFRDLIEAGLRAGRFQVESARLA
SYAILDLGMGVAVWFRDDGELTEDAVVWQFSQFALRIVGAA

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22317; Mature: 22186

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKDVAGKDVVRPSSVRSAQIRAAALDLFTRSGYEATTMADLGAAVGMRGPSLYKHVASK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
QDVLEQIMTGTMEALLAAHRTAVATTADPVERLRRATEAHVRYHARHRLEAFVGNREIRS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LTQPNRERVLGLRAEYERCFRDLIEAGLRAGRFQVESARLASYAILDLGMGVAVWFRDDG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCEEEEECCCC
ELTEDAVVWQFSQFALRIVGAA
CCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKDVAGKDVVRPSSVRSAQIRAAALDLFTRSGYEATTMADLGAAVGMRGPSLYKHVASK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
QDVLEQIMTGTMEALLAAHRTAVATTADPVERLRRATEAHVRYHARHRLEAFVGNREIRS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LTQPNRERVLGLRAEYERCFRDLIEAGLRAGRFQVESARLASYAILDLGMGVAVWFRDDG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCEEEEECCCC
ELTEDAVVWQFSQFALRIVGAA
CCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]