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The map label for this gene is aroB [H]

Identifier: 158313537

GI number: 158313537

Start: 2033332

End: 2034447

Strand: Direct

Name: aroB [H]

Synonym: Franean1_1701

Alternate gene names: 158313537

Gene position: 2033332-2034447 (Clockwise)

Preceding gene: 158313536

Following gene: 158313538

Centisome position: 22.64

GC content: 73.92

Gene sequence:

>1116_bases
ATGTGCGCGATGAAGGTTTCCGACATGGTCCGCATCCAGGTCACCCCGTCCGGTGACCGGGCCTACGACGTGGTGCTGGG
CGAGGGCGCCCTCTGCGAGCTACCGGCGCTGGCCGCGGGGCGCACCCGGGTCATGGTCATTCACCCGCGAGCGCTGCGGG
CCACCGCCGCGGCGGTCATCGCCGAGCTGCGGGCCGGCGCCGGTGCCGGCGTCGAGACGCACGCGTTCGAGGTGCCGGAC
GGCGAGGAGGCCAAGCAGCTGCGGGTCGCGGGCGCCTGCTGGGACGCCCTCGGCCGTGTCGGCTTCACCCGCGACGACCT
GGTGGTCGGGCTCGGCGGCGGGACGACGACCGACCTGGCCGGGTTCGCCGCGGCGGGCTGGCTGCGTGGTGTCGACGTCA
TCCAGGTGCCCACCACCGTGCTCGGGATGGTCGATGCGGCGGTCGGTGGCAAGACGGGCATCGACATCGAGGCGGGCAAG
AACCTCGTCGGCGCCTTCCACCAGCCGCTGGCGGTGCTCTGTGACCTGTCGACCCTGGCCAGCCTGCCGGCGGTCGAGGT
CCGGGCCGGGCTCGCCGAGGTCGTCAAGGCCGGGTTCATCGCCGATCCGCGCATCCTCGAGCTGCTGGAGGCCGATCCGA
CCGGGTCGGCGCGGCTGCCCGAGCTCGTCGAGCGGTCGATCCGGGTCAAGGCGGCGGTGGTGTCCGGCGACCCGCGCGAG
GCCGGCCGGCGCGAGATCCTGAACTACGGGCACACCCTCGCCCACGCGATCGAGAAGGTCGAGAACTTCTCCTGGCGGCA
CGGCGCGGCGGTCTCGGTCGGCATGGTCTTCGCCGCCGAGCTCTCCCGGCTCGTCGCCGGGCTCGACCGCGTGACCGCCG
ATCGCCACCGCGAGCTGCTGCGGGCCATCGGGCTGCCGGTGGAGTACCGGGGGGACCGCTGGCCGGCGCTGCTCGACGCG
ATGCGGGTGGACAAGAAGACCCGGGGCCGGCGGTTGCGTTTCGTTGTGCTCGAAGCGCTCGGCCGGCCGCGCGGATTCGA
CGATCCCGAGCCCGGCCTGCTGCTGGCCGCGTACGGCTCGGTCGCCGCGGGCGGTGTGAGCGCTACCGGGAACTGA

Upstream 100 bases:

>100_bases
ACGAGGAGGTGGCCGCGATCACCGTGGACACCGCCGCCCTCGGGATCGACGACGTCGTCGCCGCGATCCTGATCGAGCTC
GCCGGGAGGGCGGGGCACTG

Downstream 100 bases:

>100_bases
CCGTTCGGCTGGCACCGCGCGTGGTCCGCCGTGGGCTGCGAGGCGGCCATGCCCTCGATCTGTAGACTTTGCCGCGGCCT
GACCCGGTGACGGGCGGCGG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MCAMKVSDMVRIQVTPSGDRAYDVVLGEGALCELPALAAGRTRVMVIHPRALRATAAAVIAELRAGAGAGVETHAFEVPD
GEEAKQLRVAGACWDALGRVGFTRDDLVVGLGGGTTTDLAGFAAAGWLRGVDVIQVPTTVLGMVDAAVGGKTGIDIEAGK
NLVGAFHQPLAVLCDLSTLASLPAVEVRAGLAEVVKAGFIADPRILELLEADPTGSARLPELVERSIRVKAAVVSGDPRE
AGRREILNYGHTLAHAIEKVENFSWRHGAAVSVGMVFAAELSRLVAGLDRVTADRHRELLRAIGLPVEYRGDRWPALLDA
MRVDKKTRGRRLRFVVLEALGRPRGFDDPEPGLLLAAYGSVAAGGVSATGN

Sequences:

>Translated_371_residues
MCAMKVSDMVRIQVTPSGDRAYDVVLGEGALCELPALAAGRTRVMVIHPRALRATAAAVIAELRAGAGAGVETHAFEVPD
GEEAKQLRVAGACWDALGRVGFTRDDLVVGLGGGTTTDLAGFAAAGWLRGVDVIQVPTTVLGMVDAAVGGKTGIDIEAGK
NLVGAFHQPLAVLCDLSTLASLPAVEVRAGLAEVVKAGFIADPRILELLEADPTGSARLPELVERSIRVKAAVVSGDPRE
AGRREILNYGHTLAHAIEKVENFSWRHGAAVSVGMVFAAELSRLVAGLDRVTADRHRELLRAIGLPVEYRGDRWPALLDA
MRVDKKTRGRRLRFVVLEALGRPRGFDDPEPGLLLAAYGSVAAGGVSATGN
>Mature_371_residues
MCAMKVSDMVRIQVTPSGDRAYDVVLGEGALCELPALAAGRTRVMVIHPRALRATAAAVIAELRAGAGAGVETHAFEVPD
GEEAKQLRVAGACWDALGRVGFTRDDLVVGLGGGTTTDLAGFAAAGWLRGVDVIQVPTTVLGMVDAAVGGKTGIDIEAGK
NLVGAFHQPLAVLCDLSTLASLPAVEVRAGLAEVVKAGFIADPRILELLEADPTGSARLPELVERSIRVKAAVVSGDPRE
AGRREILNYGHTLAHAIEKVENFSWRHGAAVSVGMVFAAELSRLVAGLDRVTADRHRELLRAIGLPVEYRGDRWPALLDA
MRVDKKTRGRRLRFVVLEALGRPRGFDDPEPGLLLAAYGSVAAGGVSATGN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=346, Percent_Identity=39.8843930635838, Blast_Score=181, Evalue=8e-47,
Organism=Saccharomyces cerevisiae, GI6320332, Length=331, Percent_Identity=35.0453172205438, Blast_Score=180, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38949; Mature: 38949

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCAMKVSDMVRIQVTPSGDRAYDVVLGEGALCELPALAAGRTRVMVIHPRALRATAAAVI
CCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
AELRAGAGAGVETHAFEVPDGEEAKQLRVAGACWDALGRVGFTRDDLVVGLGGGTTTDLA
HHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHH
GFAAAGWLRGVDVIQVPTTVLGMVDAAVGGKTGIDIEAGKNLVGAFHQPLAVLCDLSTLA
HHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHCHHHHH
SLPAVEVRAGLAEVVKAGFIADPRILELLEADPTGSARLPELVERSIRVKAAVVSGDPRE
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHEEEEEEECCCCHH
AGRREILNYGHTLAHAIEKVENFSWRHGAAVSVGMVFAAELSRLVAGLDRVTADRHRELL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAIGLPVEYRGDRWPALLDAMRVDKKTRGRRLRFVVLEALGRPRGFDDPEPGLLLAAYGS
HHHCCCEEECCCCCHHHHHHHHHCHHHCCCEEHHHHHHHHCCCCCCCCCCCCEEEEECCC
VAAGGVSATGN
HHCCCCCCCCC
>Mature Secondary Structure
MCAMKVSDMVRIQVTPSGDRAYDVVLGEGALCELPALAAGRTRVMVIHPRALRATAAAVI
CCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
AELRAGAGAGVETHAFEVPDGEEAKQLRVAGACWDALGRVGFTRDDLVVGLGGGTTTDLA
HHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHH
GFAAAGWLRGVDVIQVPTTVLGMVDAAVGGKTGIDIEAGKNLVGAFHQPLAVLCDLSTLA
HHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHHCHHHHH
SLPAVEVRAGLAEVVKAGFIADPRILELLEADPTGSARLPELVERSIRVKAAVVSGDPRE
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHEEEEEEECCCCHH
AGRREILNYGHTLAHAIEKVENFSWRHGAAVSVGMVFAAELSRLVAGLDRVTADRHRELL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAIGLPVEYRGDRWPALLDAMRVDKKTRGRRLRFVVLEALGRPRGFDDPEPGLLLAAYGS
HHHCCCEEECCCCCHHHHHHHHHCHHHCCCEEHHHHHHHHCCCCCCCCCCCCEEEEECCC
VAAGGVSATGN
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]