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The map label for this gene is paaX [H]

Identifier: 158313521

GI number: 158313521

Start: 2016644

End: 2017645

Strand: Direct

Name: paaX [H]

Synonym: Franean1_1685

Alternate gene names: 158313521

Gene position: 2016644-2017645 (Clockwise)

Preceding gene: 158313517

Following gene: 158313525

Centisome position: 22.45

GC content: 73.85

Gene sequence:

>1002_bases
GTGACAGCGCCCGCGCGGCTCGCAGGTCGCGACCGTGATCCGGGTCGTGGCCGGCGCCCGACCGTCCGCCGGCCGCAGGT
CGGGGCCCAAGGAGCGAATCCGGCACCTCCAACGGTCGACGTCGTCGACCTGCCCAGGGTCCAGGCGGGCGCACAGCCCC
AGCACCTGCTCACCACCCTGCTCGGCGATTACTGGGCCGGCCGCCGGGAGCACGTCCCGTCGGTGGTGCTGGTCAGCCTG
CTCGCGGATTTCGACGTCAGCACGGTCGGTGCCCGGGCGGCGCTGAGCCGGCTGTCGCGGCGCGGGCTGCTGGAGTCGTC
CCGGATCGGCCGCAACACCTACTACGGGCTGACAGCGGAGGCCTCGGCCGCGATCCTCGCGTCGGCGAACCGGATCTTCA
CCTTCGGCCTGCGGCACGACCCGTGGGACGGGCGCTGGACGGTGGCGGCGTTCTCCATCCCCGAGGACCAGCGCGACGTG
CGGCACGCCGTGCGTGCACGGCTGCGTTGGCTGGGCTTCGCTCCGCTCTACGACGGGATGTGGGTCACCCCGCGGTCTGC
CGGTGAGGCGGCCCGCCGGGTGTTCGCCGAGTTGGGCGTCATCGCGTCGACGGTGCTGATCACGACGTCGGAGGCGCGCC
GCAGCGACCCCCGCCCGCCGATGGCCGCCTGGGATCTCACCGAGCTGCAGCGCACCTACGAGGAGTTCGTCCGCACCTAC
ACCCCCCTGTTGGAACGGGTCCGGCACGGCGAGGTGTGCGGCGCGGAGGCACTGGCCGCACGCACCGCGGTGATGGAGTC
CTGGGGGCGCTTCCCGAGCCTCGACCCGGACCTTCCGATCGACCTGCTGCCCGGCCGCTGGCCGCGGCGCGAGGCCCGCA
CGGTCTTCGCCGAGATCTACGACGGGCTGGCCGTCCCGGCTGTGGCGCGGGTCCGGGAGCTGCTGGCGGAGGTGTCGCCG
GAGCTGGCCGACCTCGTCCGGCTGCGTACGACGGTCTCCTGA

Upstream 100 bases:

>100_bases
TACAGGTCGCCCGTCAGGAGACCGACCGACGTCACCCGGACCACAGGAGATCCGGACCGATCGCGTGGAATGTCGGTAGG
GGCTCGTAAAATCGGAGAGC

Downstream 100 bases:

>100_bases
CCGGCCGGCCCGGAGTCCCCTGGCCGGCCCGGAGTCCCCTGACCGGTTGGCCCGAGTCTCGTGGGCGGTCAGCGCGGGCC
TTCTGGGCGGTCAGCCCGAG

Product: PaaX family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTAPARLAGRDRDPGRGRRPTVRRPQVGAQGANPAPPTVDVVDLPRVQAGAQPQHLLTTLLGDYWAGRREHVPSVVLVSL
LADFDVSTVGARAALSRLSRRGLLESSRIGRNTYYGLTAEASAAILASANRIFTFGLRHDPWDGRWTVAAFSIPEDQRDV
RHAVRARLRWLGFAPLYDGMWVTPRSAGEAARRVFAELGVIASTVLITTSEARRSDPRPPMAAWDLTELQRTYEEFVRTY
TPLLERVRHGEVCGAEALAARTAVMESWGRFPSLDPDLPIDLLPGRWPRREARTVFAEIYDGLAVPAVARVRELLAEVSP
ELADLVRLRTTVS

Sequences:

>Translated_333_residues
MTAPARLAGRDRDPGRGRRPTVRRPQVGAQGANPAPPTVDVVDLPRVQAGAQPQHLLTTLLGDYWAGRREHVPSVVLVSL
LADFDVSTVGARAALSRLSRRGLLESSRIGRNTYYGLTAEASAAILASANRIFTFGLRHDPWDGRWTVAAFSIPEDQRDV
RHAVRARLRWLGFAPLYDGMWVTPRSAGEAARRVFAELGVIASTVLITTSEARRSDPRPPMAAWDLTELQRTYEEFVRTY
TPLLERVRHGEVCGAEALAARTAVMESWGRFPSLDPDLPIDLLPGRWPRREARTVFAEIYDGLAVPAVARVRELLAEVSP
ELADLVRLRTTVS
>Mature_332_residues
TAPARLAGRDRDPGRGRRPTVRRPQVGAQGANPAPPTVDVVDLPRVQAGAQPQHLLTTLLGDYWAGRREHVPSVVLVSLL
ADFDVSTVGARAALSRLSRRGLLESSRIGRNTYYGLTAEASAAILASANRIFTFGLRHDPWDGRWTVAAFSIPEDQRDVR
HAVRARLRWLGFAPLYDGMWVTPRSAGEAARRVFAELGVIASTVLITTSEARRSDPRPPMAAWDLTELQRTYEEFVRTYT
PLLERVRHGEVCGAEALAARTAVMESWGRFPSLDPDLPIDLLPGRWPRREARTVFAEIYDGLAVPAVARVRELLAEVSPE
LADLVRLRTTVS

Specific function: Negative regulator of the paaZ and paaABCDEFGHIJK catabolic operons. Binds the consensus sequence 5'- WWTRTGATTCGYGWT-3'. Binding of paaX is specifically inhibited by phenylacetyl-coenzyme A [H]

COG id: COG3327

COG function: function code K; Phenylacetic acid-responsive transcriptional repressor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787666, Length=265, Percent_Identity=27.1698113207547, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012906
- InterPro:   IPR013225
- InterPro:   IPR011965 [H]

Pfam domain/function: PF07848 PaaX; PF08223 PaaX_C [H]

EC number: NA

Molecular weight: Translated: 36808; Mature: 36677

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPARLAGRDRDPGRGRRPTVRRPQVGAQGANPAPPTVDVVDLPRVQAGAQPQHLLTTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHH
LGDYWAGRREHVPSVVLVSLLADFDVSTVGARAALSRLSRRGLLESSRIGRNTYYGLTAE
HHHHHCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECCC
ASAAILASANRIFTFGLRHDPWDGRWTVAAFSIPEDQRDVRHAVRARLRWLGFAPLYDGM
HHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCE
WVTPRSAGEAARRVFAELGVIASTVLITTSEARRSDPRPPMAAWDLTELQRTYEEFVRTY
EECCCCHHHHHHHHHHHHHHHHHHHHEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
TPLLERVRHGEVCGAEALAARTAVMESWGRFPSLDPDLPIDLLPGRWPRREARTVFAEIY
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
DGLAVPAVARVRELLAEVSPELADLVRLRTTVS
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAPARLAGRDRDPGRGRRPTVRRPQVGAQGANPAPPTVDVVDLPRVQAGAQPQHLLTTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHH
LGDYWAGRREHVPSVVLVSLLADFDVSTVGARAALSRLSRRGLLESSRIGRNTYYGLTAE
HHHHHCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECCC
ASAAILASANRIFTFGLRHDPWDGRWTVAAFSIPEDQRDVRHAVRARLRWLGFAPLYDGM
HHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHCCE
WVTPRSAGEAARRVFAELGVIASTVLITTSEARRSDPRPPMAAWDLTELQRTYEEFVRTY
EECCCCHHHHHHHHHHHHHHHHHHHHEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
TPLLERVRHGEVCGAEALAARTAVMESWGRFPSLDPDLPIDLLPGRWPRREARTVFAEIY
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
DGLAVPAVARVRELLAEVSPELADLVRLRTTVS
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]