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The map label for this gene is tfdA [H]

Identifier: 158313469

GI number: 158313469

Start: 1950420

End: 1951253

Strand: Direct

Name: tfdA [H]

Synonym: Franean1_1633

Alternate gene names: 158313469

Gene position: 1950420-1951253 (Clockwise)

Preceding gene: 158313468

Following gene: 158313470

Centisome position: 21.71

GC content: 71.22

Gene sequence:

>834_bases
ATGGCCGTGACCGTCACCGAGATCAGCCCGGAGGTCGGCGTCGAGATCGCCGGCCTCGCCGGCCACCAGCTCGCCGACCC
GGCGGTCGCGGCCGACTGTCAGGTCCTGCTGGAACGCCACGGCGTCGTCGTCTACCGCGAGACCCATGTCGGCGACGACG
ACCTGGTCGCCTTCAGTCGCCTGCTCGGCCAGGTGGTCGTCGCCCCCGTGGGCGGCACGGACACCCACCCCGAGATCTCG
AAGATCACTCTGGACCCCGCCGAAAGTGTCCTGGCCGCCTACCGGCGGGGAACCTTCTTCTGGCACATCGACGGGGCCAA
CGACGAGCTGCCGCAGAAGGCCACGCTGCTGACGGCCCACCAGGTCTCCGACGAGGGCGGCGACACCGAGTTCGCCAACA
CCTACGCCGCCTACGAGGCGCTCTCCGACGCCGAGAAGGAGCAGTTCGCGAAGCTGCGCGTCGTGCACAGCTTCGCGGCC
TCACAGTCGCTGGCCGAGCCCGACGCGTCGGAGCGGACCCGCGCGCTGTGGGCGCGGGTGCCGGCCCGTGAGCACCCGCT
GGTCTGGACCCGCCGCAGCGGCCGCAGGTCGCTGCTGGTCGGCGCGACGACCGACCACGTCGTCGGCTGGCCGGCGGACG
AAAGCCGCGCCCTGCTCGACCGGCTCCTCGAGTGGTCGACCCAGCCGCGGTTCGTCCTGCGTCATCACTGGCACCGCGGC
GACCTCGTGATCTGGGACAACACCGGCATGCTGCACCGGGCGATCCCGTACACGGCGACGTCGCGCCGGTTGATGCACCG
AACGACCCTCGTGGGCGAAGAAGTCGTAGCCTGA

Upstream 100 bases:

>100_bases
CTCGACGACGACCTCACCCAGACCTGACCGCCGGACGAGCGACCCGGCACGGCGCCGTCCCCCCCGGGTGGTGGCACACC
CAGACCCGACAGGAGTAGTC

Downstream 100 bases:

>100_bases
CCTCCGCGCGCGGCACCCCCGCGCGAAGCTCTGACGTCCATCGGACGGCCGGCCCGCGGGCAAGGCTGAGGCCGGCGGGA
CGACGGACGTCCGCACTGTC

Product: taurine catabolism dioxygenase TauD/TfdA

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: 2,4-D dioxygenase [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MAVTVTEISPEVGVEIAGLAGHQLADPAVAADCQVLLERHGVVVYRETHVGDDDLVAFSRLLGQVVVAPVGGTDTHPEIS
KITLDPAESVLAAYRRGTFFWHIDGANDELPQKATLLTAHQVSDEGGDTEFANTYAAYEALSDAEKEQFAKLRVVHSFAA
SQSLAEPDASERTRALWARVPAREHPLVWTRRSGRRSLLVGATTDHVVGWPADESRALLDRLLEWSTQPRFVLRHHWHRG
DLVIWDNTGMLHRAIPYTATSRRLMHRTTLVGEEVVA

Sequences:

>Translated_277_residues
MAVTVTEISPEVGVEIAGLAGHQLADPAVAADCQVLLERHGVVVYRETHVGDDDLVAFSRLLGQVVVAPVGGTDTHPEIS
KITLDPAESVLAAYRRGTFFWHIDGANDELPQKATLLTAHQVSDEGGDTEFANTYAAYEALSDAEKEQFAKLRVVHSFAA
SQSLAEPDASERTRALWARVPAREHPLVWTRRSGRRSLLVGATTDHVVGWPADESRALLDRLLEWSTQPRFVLRHHWHRG
DLVIWDNTGMLHRAIPYTATSRRLMHRTTLVGEEVVA
>Mature_276_residues
AVTVTEISPEVGVEIAGLAGHQLADPAVAADCQVLLERHGVVVYRETHVGDDDLVAFSRLLGQVVVAPVGGTDTHPEISK
ITLDPAESVLAAYRRGTFFWHIDGANDELPQKATLLTAHQVSDEGGDTEFANTYAAYEALSDAEKEQFAKLRVVHSFAAS
QSLAEPDASERTRALWARVPAREHPLVWTRRSGRRSLLVGATTDHVVGWPADESRALLDRLLEWSTQPRFVLRHHWHRGD
LVIWDNTGMLHRAIPYTATSRRLMHRTTLVGEEVVA

Specific function: Involved in degradation of the herbicide 2,4- dichlorophenoxyacetic acid (2,4-D). Is also able to degrade 2- methyl-4-chlorophenoxyacetic acid and 3-chlorobenzoic acid [H]

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=283, Percent_Identity=28.9752650176678, Blast_Score=97, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322971, Length=264, Percent_Identity=28.030303030303, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 30585; Mature: 30453

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTVTEISPEVGVEIAGLAGHQLADPAVAADCQVLLERHGVVVYRETHVGDDDLVAFSR
CEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHH
LLGQVVVAPVGGTDTHPEISKITLDPAESVLAAYRRGTFFWHIDGANDELPQKATLLTAH
HHHHEEEECCCCCCCCCCCEEEEECHHHHHHHHHHCCEEEEEEECCCCCCCCHHHEEEEE
QVSDEGGDTEFANTYAAYEALSDAEKEQFAKLRVVHSFAASQSLAEPDASERTRALWARV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
PAREHPLVWTRRSGRRSLLVGATTDHVVGWPADESRALLDRLLEWSTQPRFVLRHHWHRG
CCCCCCEEEEECCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHCCCCCCCHHHCCCCCC
DLVIWDNTGMLHRAIPYTATSRRLMHRTTLVGEEVVA
CEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVTVTEISPEVGVEIAGLAGHQLADPAVAADCQVLLERHGVVVYRETHVGDDDLVAFSR
EEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHH
LLGQVVVAPVGGTDTHPEISKITLDPAESVLAAYRRGTFFWHIDGANDELPQKATLLTAH
HHHHEEEECCCCCCCCCCCEEEEECHHHHHHHHHHCCEEEEEEECCCCCCCCHHHEEEEE
QVSDEGGDTEFANTYAAYEALSDAEKEQFAKLRVVHSFAASQSLAEPDASERTRALWARV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
PAREHPLVWTRRSGRRSLLVGATTDHVVGWPADESRALLDRLLEWSTQPRFVLRHHWHRG
CCCCCCEEEEECCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHCCCCCCCHHHCCCCCC
DLVIWDNTGMLHRAIPYTATSRRLMHRTTLVGEEVVA
CEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8779585 [H]