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The map label for this gene is dapA1 [H]

Identifier: 158313051

GI number: 158313051

Start: 1432260

End: 1433225

Strand: Direct

Name: dapA1 [H]

Synonym: Franean1_1199

Alternate gene names: 158313051

Gene position: 1432260-1433225 (Clockwise)

Preceding gene: 158313050

Following gene: 158313052

Centisome position: 15.95

GC content: 71.12

Gene sequence:

>966_bases
GTGGCAGGTATGTCAGCATTGCCCCCGGCCCCGTTCGGGCGGATGATCACGGCGATGATCACGCCGTTCACCGCGGACGG
CGGGCTGGACGTCCCCGGCGCCGCGGCGCTCGCGGAGCATCTCGTCGACGCCGGTAATGACGCGCTGGTCATCAACGGCA
CCACGGGCGAGTCGCCCACGACGTCGGATGCCGAGAAGGACATCCTGGTGCGCGCCGTCCGTGACGCGGTCGGCAGCCGC
GCCCAGGTGATCGCCGGCGTCGGCACGAACGACACCCGGCACACCGTCGAGCTGGCCGAGGCGGCCGAGAAGGCGGGCGC
CAACGGCCTGCTCGTGGTCGCGCCGTATTACAACAAGCCGCCGCAGGCCGGGCTGCTCGCGCACTTCCGGGCAGTCGCCG
ACGCGACATCCCTGCCTGTGATGATCTACGATATTCCCGGCAGGTCCGGTGTACCGGTCGCGACCGAGACTCTCCTGAAG
CTGGCCGAACACTCGCGTATCGTCGCGGTCAAGGACGCCAAGGACGATCTCTCCGCGTCTTCGTGGGTACTGGCCAACAC
CGGCCTCGCCTACTACTCGGGCACGGACGTGCTCAATCTTCCGCTTCTGTCCGTCGGTGCGTGCGGTGTGGTCAGTGTCG
TCGGTCACGTGGCCAGCCCCGCCATTCGGGCGATGATCGAGGCCTTCGGGGCCGGTGAGGTGGGTCGGGCGATCGCGCTC
CACAAGGGCTTGCTGCCCGCATATCAGGGAATCTTCCGCACTCAGGGTGTGATCACGGCAAAGGCGGCGCTGGCCATGGC
CGGCCTGCCCGCGGGGCCGGTCCGCTCCCCGCTCGTCGACGCGACGGAGGCCGAGCGAGCCCAGCTGCGTGCCGACCTGG
CCGCGGCCGTGCTCGATCCCGGGCCCCCGCCCGGGCCCGCGGGGCCGGGCGCCGCCGCGGTCGTCCCGGGGACGGCGGCC
TCATGA

Upstream 100 bases:

>100_bases
GACCCGGCGTGACCGGTCGGTGCCGCCCGCTCGCGGTGGGGGGCCGCCGACTGGCGCCGCTCGGCGACTGTCGGAGGAGA
TGTCGGAGGTGCCCGCTAGC

Downstream 100 bases:

>100_bases
TGCATCCGCACCCGGAGCTGGGCCCCCCACCGCCGCTGCGTGCCGACGGCCTGAGGATCATCCCGCTCGGCGGCCTCGGT
GAGATCGGTCGCAACATGAC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS 1 [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MAGMSALPPAPFGRMITAMITPFTADGGLDVPGAAALAEHLVDAGNDALVINGTTGESPTTSDAEKDILVRAVRDAVGSR
AQVIAGVGTNDTRHTVELAEAAEKAGANGLLVVAPYYNKPPQAGLLAHFRAVADATSLPVMIYDIPGRSGVPVATETLLK
LAEHSRIVAVKDAKDDLSASSWVLANTGLAYYSGTDVLNLPLLSVGACGVVSVVGHVASPAIRAMIEAFGAGEVGRAIAL
HKGLLPAYQGIFRTQGVITAKAALAMAGLPAGPVRSPLVDATEAERAQLRADLAAAVLDPGPPPGPAGPGAAAVVPGTAA
S

Sequences:

>Translated_321_residues
MAGMSALPPAPFGRMITAMITPFTADGGLDVPGAAALAEHLVDAGNDALVINGTTGESPTTSDAEKDILVRAVRDAVGSR
AQVIAGVGTNDTRHTVELAEAAEKAGANGLLVVAPYYNKPPQAGLLAHFRAVADATSLPVMIYDIPGRSGVPVATETLLK
LAEHSRIVAVKDAKDDLSASSWVLANTGLAYYSGTDVLNLPLLSVGACGVVSVVGHVASPAIRAMIEAFGAGEVGRAIAL
HKGLLPAYQGIFRTQGVITAKAALAMAGLPAGPVRSPLVDATEAERAQLRADLAAAVLDPGPPPGPAGPGAAAVVPGTAA
S
>Mature_320_residues
AGMSALPPAPFGRMITAMITPFTADGGLDVPGAAALAEHLVDAGNDALVINGTTGESPTTSDAEKDILVRAVRDAVGSRA
QVIAGVGTNDTRHTVELAEAAEKAGANGLLVVAPYYNKPPQAGLLAHFRAVADATSLPVMIYDIPGRSGVPVATETLLKL
AEHSRIVAVKDAKDDLSASSWVLANTGLAYYSGTDVLNLPLLSVGACGVVSVVGHVASPAIRAMIEAFGAGEVGRAIALH
KGLLPAYQGIFRTQGVITAKAALAMAGLPAGPVRSPLVDATEAERAQLRADLAAAVLDPGPPPGPAGPGAAAVVPGTAAS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=283, Percent_Identity=26.8551236749117, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI13540533, Length=301, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1788823, Length=288, Percent_Identity=32.2916666666667, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786463, Length=270, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI87082415, Length=294, Percent_Identity=27.5510204081633, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789620, Length=229, Percent_Identity=25.764192139738, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32161; Mature: 32030

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGMSALPPAPFGRMITAMITPFTADGGLDVPGAAALAEHLVDAGNDALVINGTTGESPT
CCCCCCCCCCCHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCC
TSDAEKDILVRAVRDAVGSRAQVIAGVGTNDTRHTVELAEAAEKAGANGLLVVAPYYNKP
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC
PQAGLLAHFRAVADATSLPVMIYDIPGRSGVPVATETLLKLAEHSRIVAVKDAKDDLSAS
CCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCC
SWVLANTGLAYYSGTDVLNLPLLSVGACGVVSVVGHVASPAIRAMIEAFGAGEVGRAIAL
CEEEECCCEEEECCCCEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HKGLLPAYQGIFRTQGVITAKAALAMAGLPAGPVRSPLVDATEAERAQLRADLAAAVLDP
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GPPPGPAGPGAAAVVPGTAAS
CCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
AGMSALPPAPFGRMITAMITPFTADGGLDVPGAAALAEHLVDAGNDALVINGTTGESPT
CCCCCCCCCCHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCC
TSDAEKDILVRAVRDAVGSRAQVIAGVGTNDTRHTVELAEAAEKAGANGLLVVAPYYNKP
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCC
PQAGLLAHFRAVADATSLPVMIYDIPGRSGVPVATETLLKLAEHSRIVAVKDAKDDLSAS
CCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCC
SWVLANTGLAYYSGTDVLNLPLLSVGACGVVSVVGHVASPAIRAMIEAFGAGEVGRAIAL
CEEEECCCEEEECCCCEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HKGLLPAYQGIFRTQGVITAKAALAMAGLPAGPVRSPLVDATEAERAQLRADLAAAVLDP
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GPPPGPAGPGAAAVVPGTAAS
CCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]