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The map label for this gene is thyX [H]

Identifier: 158313047

GI number: 158313047

Start: 1424991

End: 1425815

Strand: Direct

Name: thyX [H]

Synonym: Franean1_1195

Alternate gene names: 158313047

Gene position: 1424991-1425815 (Clockwise)

Preceding gene: 158313046

Following gene: 158313048

Centisome position: 15.86

GC content: 70.79

Gene sequence:

>825_bases
GTGGTGGAGGTCGGAGTGCCTGACGAGATCGACGAGACCGCCGGGCTGGAGCAGCTCGACGAGCCGAGCCCCGGCCCCGT
GGCGGCCCGGATGAAGGTCCAGGTCATAGCCCGAACGGAGTTCCTCCCGCCGGACGACGTCCCGTGGAGCACCGACGCCG
AGGGTGGCCAGGCGCTCGCGGAGTTCGCCGGTCGCGCCTGCTACCAGAGCTGGAACAAGCCGAACCCGGCGACGGCGACG
AACGCCGGCTACCTGCGGCACATCCTCGACGTCGGCCACCTGTCGGTGCTCGAGCACGGAACGGTCTCGCTGTACATCAC
CGGTGTCTCCCGGAGCCTGACCCACGAGCTCGTCCGGCACCGGCACTTCTCCTACAGCCAGCTCTCCCAGCGCTACGTCC
CCGAGCACGATGCGGCCGTCGTCGAGCCCGAGGTGATCGCCTCCGACCCCGAGTTGCACGCCCTGTTCACCGAGGCGGCC
GCCGCGTCCATGGACGCGTACGCGCGGCTGCTGGAGGGTCTCGAGAAGCGGTTCGCCGACGTGTCCGCGCCGACCTCGCG
CCGCAAGCAGGCTCGTCAGGCGGCCCGTTCGGCGCTGATGAACGCCACCGAGACCAGGATCGTCGTCACCGGCAACTACC
GCGCCTGGCGGCACTTCATCGCGATGCGGGCCAGTGAGCACGCCGACGTCGAGATCCGTGGGCTGGCGATCGCCGCGCTG
CGCGCCCTGCGGGATGTGGCACCGAACGTCTTCGCGGACTTCCGGGTGACCACCCTCGACGACGGCACGGAGGTGGCTTC
CAGCCCGCTGGTCGGCGAGGGCTGA

Upstream 100 bases:

>100_bases
ACGGTCTGGCCGCACGGGCGCGGTCCGGCGCGTGAACACGGCTGGCGCGAACACGGTCCGGCTGCGCGGACGTCCACGAG
CGGAGACGGTGGAGGTCGCT

Downstream 100 bases:

>100_bases
CCCAGGCCGGGGCTGACGAAGCCGGGCGGGCCCGTTCCGGGCGCGCCGGAACCCGTCCCGCCGTCCGCGCTGGACCATGC
CGCCCATGTCCGTCCATGCC

Product: FAD-dependent thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MVEVGVPDEIDETAGLEQLDEPSPGPVAARMKVQVIARTEFLPPDDVPWSTDAEGGQALAEFAGRACYQSWNKPNPATAT
NAGYLRHILDVGHLSVLEHGTVSLYITGVSRSLTHELVRHRHFSYSQLSQRYVPEHDAAVVEPEVIASDPELHALFTEAA
AASMDAYARLLEGLEKRFADVSAPTSRRKQARQAARSALMNATETRIVVTGNYRAWRHFIAMRASEHADVEIRGLAIAAL
RALRDVAPNVFADFRVTTLDDGTEVASSPLVGEG

Sequences:

>Translated_274_residues
MVEVGVPDEIDETAGLEQLDEPSPGPVAARMKVQVIARTEFLPPDDVPWSTDAEGGQALAEFAGRACYQSWNKPNPATAT
NAGYLRHILDVGHLSVLEHGTVSLYITGVSRSLTHELVRHRHFSYSQLSQRYVPEHDAAVVEPEVIASDPELHALFTEAA
AASMDAYARLLEGLEKRFADVSAPTSRRKQARQAARSALMNATETRIVVTGNYRAWRHFIAMRASEHADVEIRGLAIAAL
RALRDVAPNVFADFRVTTLDDGTEVASSPLVGEG
>Mature_274_residues
MVEVGVPDEIDETAGLEQLDEPSPGPVAARMKVQVIARTEFLPPDDVPWSTDAEGGQALAEFAGRACYQSWNKPNPATAT
NAGYLRHILDVGHLSVLEHGTVSLYITGVSRSLTHELVRHRHFSYSQLSQRYVPEHDAAVVEPEVIASDPELHALFTEAA
AASMDAYARLLEGLEKRFADVSAPTSRRKQARQAARSALMNATETRIVVTGNYRAWRHFIAMRASEHADVEIRGLAIAAL
RALRDVAPNVFADFRVTTLDDGTEVASSPLVGEG

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 29865; Mature: 29865

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEVGVPDEIDETAGLEQLDEPSPGPVAARMKVQVIARTEFLPPDDVPWSTDAEGGQALA
CCCCCCCCCCHHHCCHHHCCCCCCCCEEHHEEEEEEEECCCCCCCCCCCCCCCCHHHHHH
EFAGRACYQSWNKPNPATATNAGYLRHILDVGHLSVLEHGTVSLYITGVSRSLTHELVRH
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHH
RHFSYSQLSQRYVPEHDAAVVEPEVIASDPELHALFTEAAAASMDAYARLLEGLEKRFAD
CCCCHHHHHHHCCCCCCCEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSAPTSRRKQARQAARSALMNATETRIVVTGNYRAWRHFIAMRASEHADVEIRGLAIAAL
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEHHHHHHHH
RALRDVAPNVFADFRVTTLDDGTEVASSPLVGEG
HHHHHHCCCHHHCCEEEEECCCHHHHCCCCCCCC
>Mature Secondary Structure
MVEVGVPDEIDETAGLEQLDEPSPGPVAARMKVQVIARTEFLPPDDVPWSTDAEGGQALA
CCCCCCCCCCHHHCCHHHCCCCCCCCEEHHEEEEEEEECCCCCCCCCCCCCCCCHHHHHH
EFAGRACYQSWNKPNPATATNAGYLRHILDVGHLSVLEHGTVSLYITGVSRSLTHELVRH
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHH
RHFSYSQLSQRYVPEHDAAVVEPEVIASDPELHALFTEAAAASMDAYARLLEGLEKRFAD
CCCCHHHHHHHCCCCCCCEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSAPTSRRKQARQAARSALMNATETRIVVTGNYRAWRHFIAMRASEHADVEIRGLAIAAL
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEHHHHHHHH
RALRDVAPNVFADFRVTTLDDGTEVASSPLVGEG
HHHHHHCCCHHHCCEEEEECCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA