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The map label for this gene is frr [H]

Identifier: 158313016

GI number: 158313016

Start: 1386704

End: 1387261

Strand: Direct

Name: frr [H]

Synonym: Franean1_1164

Alternate gene names: 158313016

Gene position: 1386704-1387261 (Clockwise)

Preceding gene: 158313015

Following gene: 158313017

Centisome position: 15.44

GC content: 66.49

Gene sequence:

>558_bases
GTGATCGACGACACGCTCCTCGAGGCCGAGGAGAAGATGGACAAGGCCGTCTCGGTCGCCAAGGACGACTTCGCCAACAT
CCGCACGGGGCGGATCACGCCAGCGGTTTTCGGGAAGGTCCTGGTGGACTACTACGGCGCTCCCACGCCAGTGCAGCAGC
TCGCCTCGTTCCACATCCCCGAGCCGCGCATGGTCATCATCACCCCGTACGACAAGTCGTCGCTCGGCGCGGTGGAGAAG
GCCGTCCGTGACTCCGACCTCGGGGTCAACCCGAGCAACGACGGGACGATCATTCGGTGCGTCTTCCCGGAGCTGTCCGA
GCAGCGTCGTCGTGACCTGGTGAAGGTGGCCCGCACCAAGGCCGAGGAGGCCCGGGTCAGCATCCGCAACATCCGCCGGC
ACGCGAAGGACGCGATCGACCGGATCGTCCGCGACGGCGAGGCCGGCGAGGACGAGGGACGCCGCGGGGAGAAGGACCTC
GATGAGGCCACCCACCGTTACGTCAGCCAGGTCGACGAACTGCTTCGCATCAAGGAGTCGGACCTGTTGTCGGTCTGA

Upstream 100 bases:

>100_bases
TTTTCGACCTCCTGACCGAGGGGAACATCTCCCGCGCCGTCCGGGGTGAGAAGATCGGCACGCTGGTCGGAGTCGAGACG
TACGGAACGGAAGGTACGCG

Downstream 100 bases:

>100_bases
CCCTCGACCAGCGCCCGTCCACGTGCGACGCCGTGCCCATCCGCTGTCCCGGCCCCTGCGCCCGGGTTCCCGTCCCCGTC
TCCGTCCCGTCGGCAAGCTG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIDDTLLEAEEKMDKAVSVAKDDFANIRTGRITPAVFGKVLVDYYGAPTPVQQLASFHIPEPRMVIITPYDKSSLGAVEK
AVRDSDLGVNPSNDGTIIRCVFPELSEQRRRDLVKVARTKAEEARVSIRNIRRHAKDAIDRIVRDGEAGEDEGRRGEKDL
DEATHRYVSQVDELLRIKESDLLSV

Sequences:

>Translated_185_residues
MIDDTLLEAEEKMDKAVSVAKDDFANIRTGRITPAVFGKVLVDYYGAPTPVQQLASFHIPEPRMVIITPYDKSSLGAVEK
AVRDSDLGVNPSNDGTIIRCVFPELSEQRRRDLVKVARTKAEEARVSIRNIRRHAKDAIDRIVRDGEAGEDEGRRGEKDL
DEATHRYVSQVDELLRIKESDLLSV
>Mature_185_residues
MIDDTLLEAEEKMDKAVSVAKDDFANIRTGRITPAVFGKVLVDYYGAPTPVQQLASFHIPEPRMVIITPYDKSSLGAVEK
AVRDSDLGVNPSNDGTIIRCVFPELSEQRRRDLVKVARTKAEEARVSIRNIRRHAKDAIDRIVRDGEAGEDEGRRGEKDL
DEATHRYVSQVDELLRIKESDLLSV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=25, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=42.0765027322404, Blast_Score=156, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=24.8554913294798, Blast_Score=63, Evalue=1e-10,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20745; Mature: 20745

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDTLLEAEEKMDKAVSVAKDDFANIRTGRITPAVFGKVLVDYYGAPTPVQQLASFHIP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
EPRMVIITPYDKSSLGAVEKAVRDSDLGVNPSNDGTIIRCVFPELSEQRRRDLVKVARTK
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
AEEARVSIRNIRRHAKDAIDRIVRDGEAGEDEGRRGEKDLDEATHRYVSQVDELLRIKES
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLLSV
HHCCC
>Mature Secondary Structure
MIDDTLLEAEEKMDKAVSVAKDDFANIRTGRITPAVFGKVLVDYYGAPTPVQQLASFHIP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
EPRMVIITPYDKSSLGAVEKAVRDSDLGVNPSNDGTIIRCVFPELSEQRRRDLVKVARTK
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
AEEARVSIRNIRRHAKDAIDRIVRDGEAGEDEGRRGEKDLDEATHRYVSQVDELLRIKES
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLLSV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA