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The map label for this gene is rnc [H]

Identifier: 158312991

GI number: 158312991

Start: 1359075

End: 1359995

Strand: Direct

Name: rnc [H]

Synonym: Franean1_1139

Alternate gene names: 158312991

Gene position: 1359075-1359995 (Clockwise)

Preceding gene: 158312990

Following gene: 158312992

Centisome position: 15.13

GC content: 73.72

Gene sequence:

>921_bases
ATGAGCCGGTCACAGTCGGTCCCCCCGCCGCGGGACGGGTTGGTCGAGGCGCTCGACGTCCACATCGACCCCGAGCTGCT
CGACCGCGCGCTGACCCACCGTTCGTACGCGTACGAGAACGGCGGGCTGCCCACGAACGAGCGGCTGGAGTTCCTCGGTG
ACGCGGTGCTCGGCCTGATCGTCACGGCCGCGCTGTTCCGCCGCCATCCCGACCTCCCCGAGGGGCAGCTCGCCAAGCAG
CGTGCCTCGGTGGTGAACATGCGGGCACTGGCCGACGTCGCGCGGCGGATCGGTACGGCGGGCATCGGGCCCTACCTGCT
CCTCGGCCGCGGCGAGGAGGCGACCGGCGGGCGGGACAAGCCCAGCATCCTGGCCGACACGCTGGAGGCTGTGATCGGGG
CCGTCTACCTTTCGAACAGCCTCGACGTGGCCTCCGGGTTCGTCCACCGGCTCTTCGACCCACTCCTCGACGAGGCGGCC
GGGCGCGGCGCCGGGTTGGACTGGAAGACCTCGCTGCAGGAGCAGACGGCTCTGCTGGGCCTCGGCCCGCCCGACTATGC
CGTCACCGAGGCCGGCCCCGATCACGCGAAGCGGTTCACCGCGTTCGCGCGGGTCGCCGGCGAGGTGCTCGGCGAGGGTG
AGGGCGGTAGCAAGAAGGAGGCCGAGCAGCGCGCCGCGGCCGCCGCCTTCGCGGTGCTCGAGAAGCGCTCGGCGGTGAAC
GCCGAGGACGAGCTGACGGCCGCCGCGTCCGCCGATCCGGGCGATACCGCCGCCGGTTTGGGTAACGGAGCTGCCGCTTC
GGCTAACGGCGCCGCGTCGGGCCGGGCGTCCGCGGTGGACGGAACGGGGCCGGCGAGCGATGCGGACGTGGACGTGGCGG
TGAGGGGCGACGCGACGCCGGCGGCGCGGGACTCCCGATGA

Upstream 100 bases:

>100_bases
GCGTCGCCGCGGGCGCCGTGCGCGCCGGGCTCTCCGGGGCGGTGCGGCAGGCCATGGCGACGCTCGTCGACCGCCGCCGG
GAACTGGCGGGGCTGTCCCG

Downstream 100 bases:

>100_bases
CTCTCGCCATTGGTGATGCCTGAGCTGCCCGAGGTCGAGGTCGTCCGCCGGGGCCTCGAGCGCGGGGTGGTCGGCCGCAC
TGTCGCCGAGGTGGAGGTCC

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSRSQSVPPPRDGLVEALDVHIDPELLDRALTHRSYAYENGGLPTNERLEFLGDAVLGLIVTAALFRRHPDLPEGQLAKQ
RASVVNMRALADVARRIGTAGIGPYLLLGRGEEATGGRDKPSILADTLEAVIGAVYLSNSLDVASGFVHRLFDPLLDEAA
GRGAGLDWKTSLQEQTALLGLGPPDYAVTEAGPDHAKRFTAFARVAGEVLGEGEGGSKKEAEQRAAAAAFAVLEKRSAVN
AEDELTAAASADPGDTAAGLGNGAAASANGAASGRASAVDGTGPASDADVDVAVRGDATPAARDSR

Sequences:

>Translated_306_residues
MSRSQSVPPPRDGLVEALDVHIDPELLDRALTHRSYAYENGGLPTNERLEFLGDAVLGLIVTAALFRRHPDLPEGQLAKQ
RASVVNMRALADVARRIGTAGIGPYLLLGRGEEATGGRDKPSILADTLEAVIGAVYLSNSLDVASGFVHRLFDPLLDEAA
GRGAGLDWKTSLQEQTALLGLGPPDYAVTEAGPDHAKRFTAFARVAGEVLGEGEGGSKKEAEQRAAAAAFAVLEKRSAVN
AEDELTAAASADPGDTAAGLGNGAAASANGAASGRASAVDGTGPASDADVDVAVRGDATPAARDSR
>Mature_305_residues
SRSQSVPPPRDGLVEALDVHIDPELLDRALTHRSYAYENGGLPTNERLEFLGDAVLGLIVTAALFRRHPDLPEGQLAKQR
ASVVNMRALADVARRIGTAGIGPYLLLGRGEEATGGRDKPSILADTLEAVIGAVYLSNSLDVASGFVHRLFDPLLDEAAG
RGAGLDWKTSLQEQTALLGLGPPDYAVTEAGPDHAKRFTAFARVAGEVLGEGEGGSKKEAEQRAAAAAFAVLEKRSAVNA
EDELTAAASADPGDTAAGLGNGAAASANGAASGRASAVDGTGPASDADVDVAVRGDATPAARDSR

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=212, Percent_Identity=34.9056603773585, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI155030234, Length=212, Percent_Identity=34.9056603773585, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1788920, Length=214, Percent_Identity=39.2523364485981, Blast_Score=113, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193202651, Length=223, Percent_Identity=30.9417040358744, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17506883, Length=223, Percent_Identity=30.9417040358744, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137682, Length=212, Percent_Identity=33.4905660377358, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 31409; Mature: 31278

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSQSVPPPRDGLVEALDVHIDPELLDRALTHRSYAYENGGLPTNERLEFLGDAVLGLI
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VTAALFRRHPDLPEGQLAKQRASVVNMRALADVARRIGTAGIGPYLLLGRGEEATGGRDK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
PSILADTLEAVIGAVYLSNSLDVASGFVHRLFDPLLDEAAGRGAGLDWKTSLQEQTALLG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEE
LGPPDYAVTEAGPDHAKRFTAFARVAGEVLGEGEGGSKKEAEQRAAAAAFAVLEKRSAVN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
AEDELTAAASADPGDTAAGLGNGAAASANGAASGRASAVDGTGPASDADVDVAVRGDATP
CHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCC
AARDSR
CCCCCC
>Mature Secondary Structure 
SRSQSVPPPRDGLVEALDVHIDPELLDRALTHRSYAYENGGLPTNERLEFLGDAVLGLI
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VTAALFRRHPDLPEGQLAKQRASVVNMRALADVARRIGTAGIGPYLLLGRGEEATGGRDK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
PSILADTLEAVIGAVYLSNSLDVASGFVHRLFDPLLDEAAGRGAGLDWKTSLQEQTALLG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEE
LGPPDYAVTEAGPDHAKRFTAFARVAGEVLGEGEGGSKKEAEQRAAAAAFAVLEKRSAVN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
AEDELTAAASADPGDTAAGLGNGAAASANGAASGRASAVDGTGPASDADVDVAVRGDATP
CHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCC
AARDSR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA