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The map label for this gene is sigE [H]

Identifier: 158312896

GI number: 158312896

Start: 1221972

End: 1222529

Strand: Direct

Name: sigE [H]

Synonym: Franean1_1042

Alternate gene names: 158312896

Gene position: 1221972-1222529 (Clockwise)

Preceding gene: 158312893

Following gene: 158312897

Centisome position: 13.6

GC content: 70.43

Gene sequence:

>558_bases
ATGACAGTCGTGGAAGGGTGGCGGCCCGTGCCTGCGCGGAGCGACGCCGCCCGTAGCGCCGTCGCGCGGGACGCCGACGC
CGCTCTGACGGCGTTGTACTCCGAGCACTACCGATCCCTCGTCCGTCTCGCGGCACTGCTGCTGGATGACATCGGGTTGT
GCGAGGAGGTCGTGCAGGACGCCTACATCCGGGTGCACAGTGCCTGGGGTCGGCTCCAGGACCGGGACAAGGCCCTGGCC
TACCTCCGTCAGACGGTGGTCAATCTCGCACGGTCCACCCTCCGGCGTCGACTGGTCGCTCTCAAGCACGCCCCCAAGCC
GATGCCCGACGCCGCGAGCGCCGAAGAGGGGGCCTACTCTCTGGTCGAGCGGGCCGCCGTCGTCCAGGCACTGCGGGAGC
TGCCCAGACGGCAACGGGAAGCGGTCGTGCTCCGCTACTACGCGGACATGTCGGAGGCTGACGCCGCCGCGGTGATGGGC
TGCAGCGTCGGGTCGGTGAAGGCCTACACGTCACGGGGGCTGGCGGCACTGAGCGGCAAGCTGGAGGGCCTGCGGTGA

Upstream 100 bases:

>100_bases
CCAGGAGAACTGAGGGGTGTCGGCGTGCCGCGCGACGCGATAGAACTTCTGGGACAACCTTGGAGGGTCGGCGCGCGTCA
GACTTTGCGTGACCGCGCCC

Downstream 100 bases:

>100_bases
GCAGCGGGCTCGAACCGGAGGAGCTCACCCGCCTGCTGCGGGCGGCGGTGGAGCCCGTGCGGGCGTCCCCCGACGCGCTG
CACCGCATCCGGGCCGGGGT

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTVVEGWRPVPARSDAARSAVARDADAALTALYSEHYRSLVRLAALLLDDIGLCEEVVQDAYIRVHSAWGRLQDRDKALA
YLRQTVVNLARSTLRRRLVALKHAPKPMPDAASAEEGAYSLVERAAVVQALRELPRRQREAVVLRYYADMSEADAAAVMG
CSVGSVKAYTSRGLAALSGKLEGLR

Sequences:

>Translated_185_residues
MTVVEGWRPVPARSDAARSAVARDADAALTALYSEHYRSLVRLAALLLDDIGLCEEVVQDAYIRVHSAWGRLQDRDKALA
YLRQTVVNLARSTLRRRLVALKHAPKPMPDAASAEEGAYSLVERAAVVQALRELPRRQREAVVLRYYADMSEADAAAVMG
CSVGSVKAYTSRGLAALSGKLEGLR
>Mature_184_residues
TVVEGWRPVPARSDAARSAVARDADAALTALYSEHYRSLVRLAALLLDDIGLCEEVVQDAYIRVHSAWGRLQDRDKALAY
LRQTVVNLARSTLRRRLVALKHAPKPMPDAASAEEGAYSLVERAAVVQALRELPRRQREAVVLRYYADMSEADAAAVMGC
SVGSVKAYTSRGLAALSGKLEGLR

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for the synthesis of the antibiotic actinomycin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014325
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20219; Mature: 20088

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVVEGWRPVPARSDAARSAVARDADAALTALYSEHYRSLVRLAALLLDDIGLCEEVVQD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYIRVHSAWGRLQDRDKALAYLRQTVVNLARSTLRRRLVALKHAPKPMPDAASAEEGAYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
LVERAAVVQALRELPRRQREAVVLRYYADMSEADAAAVMGCSVGSVKAYTSRGLAALSGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LEGLR
CCCCC
>Mature Secondary Structure 
TVVEGWRPVPARSDAARSAVARDADAALTALYSEHYRSLVRLAALLLDDIGLCEEVVQD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYIRVHSAWGRLQDRDKALAYLRQTVVNLARSTLRRRLVALKHAPKPMPDAASAEEGAYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
LVERAAVVQALRELPRRQREAVVLRYYADMSEADAAAVMGCSVGSVKAYTSRGLAALSGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LEGLR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9004230; 11342219 [H]