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The map label for this gene is rfbB [C]

Identifier: 158312817

GI number: 158312817

Start: 1126323

End: 1127315

Strand: Direct

Name: rfbB [C]

Synonym: Franean1_0963

Alternate gene names: 158312817

Gene position: 1126323-1127315 (Clockwise)

Preceding gene: 158312816

Following gene: 158312819

Centisome position: 12.54

GC content: 72.91

Gene sequence:

>993_bases
GTGCGTATCCTCGTCACCGGCGCGGCCGGTTTCATCGGTTCCACCGTCGTCGATCGGATGCTTGCTGACGGTCATTCGGT
CGTGGGCATCGACGACCTGTCGTCCGGGCGCATGGAGAATCTCACGCAGGCGGCGACCGATGCCCGGTTCTCGTTCGAGA
AGGGCGATATCACGTCGCCCGATCTCGGTGACTTCGTCGCCCGGGTCCGCCCCGACGCGGTGGCTCATCTCGCGGCGCAG
ATCGACGTCCGGATCAGCGTCGCCGACCCGCTGCTCGACGCCCGGCTGAACGTTCTCGGCACGATCAACGTGCTGGAGGC
GGCCCGGGCCGCCGGGGTGGTGAAGGTCATCCACACCTCGTCCGGCGGGTCGATCTACGGCACGCCGGCCGCGCTGCCCG
TCGACGAGTCCGTGCCACCCGCGCCCGAGTCACCGTACGCGGCCGGGAAGGCCGCCGGCGAACTGTACCTCAACGTGTAC
CGGGTGACCTACGGTGTCGCGACGACGGCGCTGGCGCTCGGGAACGTCTACGGGCCCCGCCAGGACCCGCACGGCGAGGC
CGGGGTGGTCGCCATCTTCGGCACCGCCCTGCTCGAGGGGCGCCCGACCAAGATCTTCGGTGACGGCGCGACCAGCCGGG
ACTACGTCTTCGTCGGGGACGTCGCCGACGCCTTCGCCCGGTGCGTGCCGGCCCAGGCGGCCAACGGCCTGCGGATCAAC
ATCGGGACCGGCGCCGAGACCACCGTTCTCGACCTGCACAGCCGCATCGCGCGGGTGGTCGGGGTGCCGGACGAGCCCCA
GTTCGCCCCGCCGCGCCCCGGCGAGCTGCAGCGCATCAGCCTGGACGTCGGCCTCGCGGAGCGGGAGATCGGCTGGCGGC
CGCGGATGGACCTGGACGGCGGGCTCACCCGGACCGTCGACTGGATCCGGGCCCGGATCGGCGCCCGCGCCGCCGCCTCC
GGCTCGGCCGGCGCGACCGGCGCGACCGGCTGA

Upstream 100 bases:

>100_bases
GGCCCGCACGGGCGCCGACGCGACCGAGTTCCGCCCCGACTAGGCGAGCGCCTCCCCGCTCGCGCGGGGAGGTCGGCAGC
GGGCGGTTAGGCTGCCTGCT

Downstream 100 bases:

>100_bases
CGAGACCGGGCGGGAGCGCTGGGCGTCCCACCCGGTCCACCTGTCAGGTGTTCGGGCGCTTGCCGTGGTTGGCCTTGCTC
TTCGCCCGCGCGCGCCGCTT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MRILVTGAAGFIGSTVVDRMLADGHSVVGIDDLSSGRMENLTQAATDARFSFEKGDITSPDLGDFVARVRPDAVAHLAAQ
IDVRISVADPLLDARLNVLGTINVLEAARAAGVVKVIHTSSGGSIYGTPAALPVDESVPPAPESPYAAGKAAGELYLNVY
RVTYGVATTALALGNVYGPRQDPHGEAGVVAIFGTALLEGRPTKIFGDGATSRDYVFVGDVADAFARCVPAQAANGLRIN
IGTGAETTVLDLHSRIARVVGVPDEPQFAPPRPGELQRISLDVGLAEREIGWRPRMDLDGGLTRTVDWIRARIGARAAAS
GSAGATGATG

Sequences:

>Translated_330_residues
MRILVTGAAGFIGSTVVDRMLADGHSVVGIDDLSSGRMENLTQAATDARFSFEKGDITSPDLGDFVARVRPDAVAHLAAQ
IDVRISVADPLLDARLNVLGTINVLEAARAAGVVKVIHTSSGGSIYGTPAALPVDESVPPAPESPYAAGKAAGELYLNVY
RVTYGVATTALALGNVYGPRQDPHGEAGVVAIFGTALLEGRPTKIFGDGATSRDYVFVGDVADAFARCVPAQAANGLRIN
IGTGAETTVLDLHSRIARVVGVPDEPQFAPPRPGELQRISLDVGLAEREIGWRPRMDLDGGLTRTVDWIRARIGARAAAS
GSAGATGATG
>Mature_330_residues
MRILVTGAAGFIGSTVVDRMLADGHSVVGIDDLSSGRMENLTQAATDARFSFEKGDITSPDLGDFVARVRPDAVAHLAAQ
IDVRISVADPLLDARLNVLGTINVLEAARAAGVVKVIHTSSGGSIYGTPAALPVDESVPPAPESPYAAGKAAGELYLNVY
RVTYGVATTALALGNVYGPRQDPHGEAGVVAIFGTALLEGRPTKIFGDGATSRDYVFVGDVADAFARCVPAQAANGLRIN
IGTGAETTVLDLHSRIARVVGVPDEPQFAPPRPGELQRISLDVGLAEREIGWRPRMDLDGGLTRTVDWIRARIGARAAAS
GSAGATGATG

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=322, Percent_Identity=27.3291925465839, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI7657641, Length=325, Percent_Identity=28.9230769230769, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=29.6187683284457, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=29.6187683284457, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=29.6187683284457, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4504031, Length=334, Percent_Identity=24.251497005988, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI4507709, Length=237, Percent_Identity=29.535864978903, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1788353, Length=338, Percent_Identity=32.2485207100592, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI48994969, Length=335, Percent_Identity=31.6417910447761, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=31.1178247734139, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788366, Length=347, Percent_Identity=24.207492795389, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788365, Length=267, Percent_Identity=27.7153558052434, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=329, Percent_Identity=28.5714285714286, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17568069, Length=324, Percent_Identity=28.7037037037037, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71982035, Length=338, Percent_Identity=26.6272189349112, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI115532424, Length=322, Percent_Identity=27.9503105590062, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI133901790, Length=189, Percent_Identity=30.6878306878307, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17539424, Length=189, Percent_Identity=30.6878306878307, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI133901788, Length=189, Percent_Identity=30.6878306878307, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17539422, Length=189, Percent_Identity=30.6878306878307, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI133901786, Length=189, Percent_Identity=30.6878306878307, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17507723, Length=330, Percent_Identity=24.8484848484848, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=26.4094955489614, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321437, Length=353, Percent_Identity=23.2294617563739, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21356223, Length=320, Percent_Identity=28.125, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19923002, Length=340, Percent_Identity=29.4117647058824, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24158427, Length=330, Percent_Identity=25.4545454545455, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34160; Mature: 34160

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTGAAGFIGSTVVDRMLADGHSVVGIDDLSSGRMENLTQAATDARFSFEKGDITSP
CEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCEEEECCCCCCCC
DLGDFVARVRPDAVAHLAAQIDVRISVADPLLDARLNVLGTINVLEAARAAGVVKVIHTS
CHHHHHHHCCHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEC
SGGSIYGTPAALPVDESVPPAPESPYAAGKAAGELYLNVYRVTYGVATTALALGNVYGPR
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCC
QDPHGEAGVVAIFGTALLEGRPTKIFGDGATSRDYVFVGDVADAFARCVPAQAANGLRIN
CCCCCCCCEEEEEEHHHHCCCCCEEEECCCCCCCEEEECCHHHHHHHHHHHHCCCCEEEE
IGTGAETTVLDLHSRIARVVGVPDEPQFAPPRPGELQRISLDVGLAEREIGWRPRMDLDG
ECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHCCCCCCCCCCCC
GLTRTVDWIRARIGARAAASGSAGATGATG
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRILVTGAAGFIGSTVVDRMLADGHSVVGIDDLSSGRMENLTQAATDARFSFEKGDITSP
CEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCEEEECCCCCCCC
DLGDFVARVRPDAVAHLAAQIDVRISVADPLLDARLNVLGTINVLEAARAAGVVKVIHTS
CHHHHHHHCCHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEC
SGGSIYGTPAALPVDESVPPAPESPYAAGKAAGELYLNVYRVTYGVATTALALGNVYGPR
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCC
QDPHGEAGVVAIFGTALLEGRPTKIFGDGATSRDYVFVGDVADAFARCVPAQAANGLRIN
CCCCCCCCEEEEEEHHHHCCCCCEEEECCCCCCCEEEECCHHHHHHHHHHHHCCCCEEEE
IGTGAETTVLDLHSRIARVVGVPDEPQFAPPRPGELQRISLDVGLAEREIGWRPRMDLDG
ECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHCCCCCCCCCCCC
GLTRTVDWIRARIGARAAASGSAGATGATG
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]