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The map label for this gene is engD [H]

Identifier: 158312713

GI number: 158312713

Start: 1003592

End: 1004668

Strand: Direct

Name: engD [H]

Synonym: Franean1_0857

Alternate gene names: 158312713

Gene position: 1003592-1004668 (Clockwise)

Preceding gene: 158312706

Following gene: 158312715

Centisome position: 11.17

GC content: 68.71

Gene sequence:

>1077_bases
ATGGGTCTGTCGATAGGCATCGTCGGGCTGCCCAACGTCGGCAAGTCCACGCTTTTCAATGCCCTGACCCGTAACGAGGT
CCTGGCGGCGAACTATCCGTTCGCGACGATCGAGCCCAACGTGGGCGTGGTCGGCGTGCCGGATCCGCGGCTCGCGAAGC
TCGGCGAGGTGTTCTCCAGCGCGCGGGTCGTCCCTGCGACGGTGAGCTTCGTCGACATCGCCGGGCTGGTCAGAGGCGCG
TCGGAGGGTCAGGGCCTGGGCAACCGCTTCCTCGCGAACATCCGCGAGTCGGATGCGATCTGCCAGGTCGTGCGGGTCTT
CTCGGATCCTGACGTGGTCCACGTCGAGGGAACCGTCGACCCGTCCGCGGACATCGAGACCATCAACACCGAGCTGGTGC
TGGCCGATCTTCAGACCATCGGCGCCCGCCTGCCCAAGCTGGAGAAGGAAGCCCGCCTCGACCGGTCGAAGCAGTCCCTG
CTCGCCGCGATGAAGGCGGCGCACGAGGTGCTCGACGCCGGCCGGCCGCTGTCCAGCGAGCCGTCGATCGACCGCGCGGA
GCTGCGTGAGTTGTTCCTGCTCACCGCCAAGCCGTTCCTCTACGTCTTCAACGTCGACGAGGACGTCCTGGCCGACCCCG
GTAGACACAAGGAGCTCGCCGACCTCGTGGCCCCCGCCGATGCGGTGATCCTGTGCGCGAAGGTCGAGGCCGAGCTGATC
GAGCTTCCCGAGGCCGACGCGGCCGAGCTGCTGGCCTCCCTCGGCCAGGAGGAGAGCGGGCTGGTGCAGCTCGCCCGGAT
CGGCTTCCACACCCTGGGCCTGCAGACGTACCTGACCGCGGGCCCCAAGGAGTCCCGGGCCTGGACCATCCCGGCCGGAG
CCACCGCTCCCGAGGCGGCCGGAGTCATCCACAGCGACTTCCAGCGCGGCTTCATCAAGGCCGAGATCGTCTCCTACGAC
GACCTGATGGCCGCCGGCTCCATGGCCGCGGCGCGCGCCGCCGGCCGGGTCCGCATGGAGGGCAAGGACTACGTCATGGC
GGATGGCGACATCGTCGACTTCCGCTTCAACGTCTAG

Upstream 100 bases:

>100_bases
CGCGGTGGCGTCGCTGTGGTGTCGCGGGAGCGTGCGGTGGCATTGCGACCGGGACCTCCGCGATCGGGGCCGGGCGCGAT
CACCCGTAGACTGCTCGGTC

Downstream 100 bases:

>100_bases
CCAGTTCCTCGCTCGAGCCCGACCGCGGGTCGCCGCGGGGCCTGGACGAGCCGGGCCGCCCGGGGGAGCACCGAGACGGC
GGCCTCGGCCGGGCCGCGCC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MGLSIGIVGLPNVGKSTLFNALTRNEVLAANYPFATIEPNVGVVGVPDPRLAKLGEVFSSARVVPATVSFVDIAGLVRGA
SEGQGLGNRFLANIRESDAICQVVRVFSDPDVVHVEGTVDPSADIETINTELVLADLQTIGARLPKLEKEARLDRSKQSL
LAAMKAAHEVLDAGRPLSSEPSIDRAELRELFLLTAKPFLYVFNVDEDVLADPGRHKELADLVAPADAVILCAKVEAELI
ELPEADAAELLASLGQEESGLVQLARIGFHTLGLQTYLTAGPKESRAWTIPAGATAPEAAGVIHSDFQRGFIKAEIVSYD
DLMAAGSMAAARAAGRVRMEGKDYVMADGDIVDFRFNV

Sequences:

>Translated_358_residues
MGLSIGIVGLPNVGKSTLFNALTRNEVLAANYPFATIEPNVGVVGVPDPRLAKLGEVFSSARVVPATVSFVDIAGLVRGA
SEGQGLGNRFLANIRESDAICQVVRVFSDPDVVHVEGTVDPSADIETINTELVLADLQTIGARLPKLEKEARLDRSKQSL
LAAMKAAHEVLDAGRPLSSEPSIDRAELRELFLLTAKPFLYVFNVDEDVLADPGRHKELADLVAPADAVILCAKVEAELI
ELPEADAAELLASLGQEESGLVQLARIGFHTLGLQTYLTAGPKESRAWTIPAGATAPEAAGVIHSDFQRGFIKAEIVSYD
DLMAAGSMAAARAAGRVRMEGKDYVMADGDIVDFRFNV
>Mature_357_residues
GLSIGIVGLPNVGKSTLFNALTRNEVLAANYPFATIEPNVGVVGVPDPRLAKLGEVFSSARVVPATVSFVDIAGLVRGAS
EGQGLGNRFLANIRESDAICQVVRVFSDPDVVHVEGTVDPSADIETINTELVLADLQTIGARLPKLEKEARLDRSKQSLL
AAMKAAHEVLDAGRPLSSEPSIDRAELRELFLLTAKPFLYVFNVDEDVLADPGRHKELADLVAPADAVILCAKVEAELIE
LPEADAAELLASLGQEESGLVQLARIGFHTLGLQTYLTAGPKESRAWTIPAGATAPEAAGVIHSDFQRGFIKAEIVSYDD
LMAAGSMAAARAAGRVRMEGKDYVMADGDIVDFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=41.8918918918919, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI58761502, Length=203, Percent_Identity=36.4532019704434, Blast_Score=132, Evalue=5e-31,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=49.1803278688525, Blast_Score=351, Evalue=3e-98,
Organism=Escherichia coli, GI1789574, Length=130, Percent_Identity=33.8461538461538, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=39.945652173913, Blast_Score=264, Evalue=7e-71,
Organism=Saccharomyces cerevisiae, GI6319499, Length=372, Percent_Identity=42.2043010752688, Blast_Score=255, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=35.8839050131926, Blast_Score=220, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6321649, Length=143, Percent_Identity=37.7622377622378, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24640873, Length=370, Percent_Identity=42.972972972973, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24640877, Length=370, Percent_Identity=42.972972972973, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24640875, Length=370, Percent_Identity=42.972972972973, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=40.8536585365854, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24585318, Length=181, Percent_Identity=29.8342541436464, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 38082; Mature: 37951

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSIGIVGLPNVGKSTLFNALTRNEVLAANYPFATIEPNVGVVGVPDPRLAKLGEVFSS
CCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCEEEECCCCCEEECCCHHHHHHHHHHHC
ARVVPATVSFVDIAGLVRGASEGQGLGNRFLANIRESDAICQVVRVFSDPDVVHVEGTVD
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PSADIETINTELVLADLQTIGARLPKLEKEARLDRSKQSLLAAMKAAHEVLDAGRPLSSE
CCCCCEECCHHEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PSIDRAELRELFLLTAKPFLYVFNVDEDVLADPGRHKELADLVAPADAVILCAKVEAELI
CCCCHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCHHHHHHHCCCCCEEEEEHHHHHHH
ELPEADAAELLASLGQEESGLVQLARIGFHTLGLQTYLTAGPKESRAWTIPAGATAPEAA
HCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCEEECCCCCCCCHHC
GVIHSDFQRGFIKAEIVSYDDLMAAGSMAAARAAGRVRMEGKDYVMADGDIVDFRFNV
CHHHHHHHCCCEEEEEECHHHHHHHCHHHHHHHCCEEEECCCCEEEECCCEEEEEECC
>Mature Secondary Structure 
GLSIGIVGLPNVGKSTLFNALTRNEVLAANYPFATIEPNVGVVGVPDPRLAKLGEVFSS
CCEEEEEECCCCCHHHHHHHHHCCCEEEECCCEEEECCCCCEEECCCHHHHHHHHHHHC
ARVVPATVSFVDIAGLVRGASEGQGLGNRFLANIRESDAICQVVRVFSDPDVVHVEGTVD
CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
PSADIETINTELVLADLQTIGARLPKLEKEARLDRSKQSLLAAMKAAHEVLDAGRPLSSE
CCCCCEECCHHEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PSIDRAELRELFLLTAKPFLYVFNVDEDVLADPGRHKELADLVAPADAVILCAKVEAELI
CCCCHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCHHHHHHHCCCCCEEEEEHHHHHHH
ELPEADAAELLASLGQEESGLVQLARIGFHTLGLQTYLTAGPKESRAWTIPAGATAPEAA
HCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCCEEECCCCCCCCHHC
GVIHSDFQRGFIKAEIVSYDDLMAAGSMAAARAAGRVRMEGKDYVMADGDIVDFRFNV
CHHHHHHHCCCEEEEEECHHHHHHHCHHHHHHHCCEEEECCCCEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]