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The map label for this gene is yrpG [H]

Identifier: 158312558

GI number: 158312558

Start: 819956

End: 821002

Strand: Direct

Name: yrpG [H]

Synonym: Franean1_0701

Alternate gene names: 158312558

Gene position: 819956-821002 (Clockwise)

Preceding gene: 158312556

Following gene: 158312560

Centisome position: 9.13

GC content: 69.63

Gene sequence:

>1047_bases
ATGCGCTACCTGACCTTCGGACGGCACACCGGCCTGCGGGTCTCGGAGTACGCGCTCGGGACCGCGAACTTCGGCACGGC
CGACACCAGCGCCGGTCGGGACACCTCGCGGCAGATCTTCGACGCCTTCGTCGCCGCCGGCGGTACGACGTTCGACACGT
CCAACCTCTACCAGGACGGACAGGCCGAGACCGTGCTCGGTGAGCTGCTCGGCAGTCGCCGGGACGACTTCGTCGTGATC
ACCAAGTACGGCGGGACGAGGCGGGACCAGCCCCGCCCCGGCACGACCGGCAACAGCCGAAAGATCATGATTCGCTCCCT
GGAGGCCAGCCTGCGGCGGCTGAACACGGACTACGTCGACGTCTTCATGCCGCACTTCCCCGACGGAACCACCCCGATCG
ACGAGATCCTGGCCGGGTTCGACGACCTGAGCCGCGCCGGGAAGATCCGGTACGGCGGGCTGTCCAACTTTCCGGCCTGG
CGGGTCGCCGGCGCCGTGGTCCGGGCGGACCTGCGCGGACTCGCCCCGCTGGTCGGCATCCAGACCGAGTACAGCCTGGC
CGAACGCTCCGCCGAGCGGGAACTGCTACCGATGGTGCAGGCCCATGGCCTGGGAGTGTTCCTGTACTCGCCGCTGGCCG
GAGGTCTGCTCAGCGGCAAGTACCGGCAGGGTGGGAAAGGCCGGTTGAGCGTTCGCGGCGACGCCGTCGAGCGCACCGTT
CAGCAGAGCGCCGTCGTCGACGGGGTGTTGGCCGTCGCCGACGAGATCGGCAGCACCGCGGTCCAGGTCTCGCTGGCCTG
GCTGCGTCGCCGGGCCGTGTCGGCCCGGACCGCGCTGATCCCGATCGTCGGGCCTCGCACGCTGTCCCACCTCGAGCAGT
ACCTGCGCTCGCTCGAGCTGGAACTCGACGAACAGCACTGTCGACGTCTCGACGAGATCAGCGCGATCCGGTTGGGCACT
CCGCACGAGGACGTCGCGGCAGCTCTGGCCCACGGCTTCGACGGCGACCGCACCCTGCTCCAGACCCTGTACCTCCCCGT
GATCTGA

Upstream 100 bases:

>100_bases
AGGTGCGCCTGCCCTACCCTCGGCATAAAAAGAACGACCCCTCGTTTTACTTGGTACGGCACGGGCAGCCTACCTCGCAC
CACACCCTCCGGGAGTCCTC

Downstream 100 bases:

>100_bases
CCGGTGCGCGTTCACCGACTCATCGACCGGATCGGACACTCCGGTGGCGGTTGGTCACCCGGCGCCCGGTACCGGGGTGA
GCTCCAGGTGCAGCTCGGTC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MRYLTFGRHTGLRVSEYALGTANFGTADTSAGRDTSRQIFDAFVAAGGTTFDTSNLYQDGQAETVLGELLGSRRDDFVVI
TKYGGTRRDQPRPGTTGNSRKIMIRSLEASLRRLNTDYVDVFMPHFPDGTTPIDEILAGFDDLSRAGKIRYGGLSNFPAW
RVAGAVVRADLRGLAPLVGIQTEYSLAERSAERELLPMVQAHGLGVFLYSPLAGGLLSGKYRQGGKGRLSVRGDAVERTV
QQSAVVDGVLAVADEIGSTAVQVSLAWLRRRAVSARTALIPIVGPRTLSHLEQYLRSLELELDEQHCRRLDEISAIRLGT
PHEDVAAALAHGFDGDRTLLQTLYLPVI

Sequences:

>Translated_348_residues
MRYLTFGRHTGLRVSEYALGTANFGTADTSAGRDTSRQIFDAFVAAGGTTFDTSNLYQDGQAETVLGELLGSRRDDFVVI
TKYGGTRRDQPRPGTTGNSRKIMIRSLEASLRRLNTDYVDVFMPHFPDGTTPIDEILAGFDDLSRAGKIRYGGLSNFPAW
RVAGAVVRADLRGLAPLVGIQTEYSLAERSAERELLPMVQAHGLGVFLYSPLAGGLLSGKYRQGGKGRLSVRGDAVERTV
QQSAVVDGVLAVADEIGSTAVQVSLAWLRRRAVSARTALIPIVGPRTLSHLEQYLRSLELELDEQHCRRLDEISAIRLGT
PHEDVAAALAHGFDGDRTLLQTLYLPVI
>Mature_348_residues
MRYLTFGRHTGLRVSEYALGTANFGTADTSAGRDTSRQIFDAFVAAGGTTFDTSNLYQDGQAETVLGELLGSRRDDFVVI
TKYGGTRRDQPRPGTTGNSRKIMIRSLEASLRRLNTDYVDVFMPHFPDGTTPIDEILAGFDDLSRAGKIRYGGLSNFPAW
RVAGAVVRADLRGLAPLVGIQTEYSLAERSAERELLPMVQAHGLGVFLYSPLAGGLLSGKYRQGGKGRLSVRGDAVERTV
QQSAVVDGVLAVADEIGSTAVQVSLAWLRRRAVSARTALIPIVGPRTLSHLEQYLRSLELELDEQHCRRLDEISAIRLGT
PHEDVAAALAHGFDGDRTLLQTLYLPVI

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=339, Percent_Identity=31.2684365781711, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI27436962, Length=339, Percent_Identity=31.2684365781711, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436969, Length=291, Percent_Identity=33.6769759450172, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI4504825, Length=293, Percent_Identity=33.7883959044369, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI27436966, Length=339, Percent_Identity=30.9734513274336, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI27436971, Length=339, Percent_Identity=31.2684365781711, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI223718702, Length=196, Percent_Identity=37.7551020408163, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI41152114, Length=195, Percent_Identity=35.3846153846154, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI41327764, Length=187, Percent_Identity=36.3636363636364, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI223718708, Length=168, Percent_Identity=36.3095238095238, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=33.9506172839506, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789199, Length=343, Percent_Identity=32.0699708454811, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788081, Length=305, Percent_Identity=31.1475409836066, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789375, Length=288, Percent_Identity=31.5972222222222, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788070, Length=238, Percent_Identity=32.7731092436975, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787674, Length=317, Percent_Identity=26.1829652996845, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI48994888, Length=152, Percent_Identity=30.2631578947368, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323998, Length=337, Percent_Identity=28.486646884273, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6319958, Length=305, Percent_Identity=28.8524590163934, Blast_Score=150, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319951, Length=339, Percent_Identity=26.2536873156342, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6325169, Length=333, Percent_Identity=26.1261261261261, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322615, Length=259, Percent_Identity=27.7992277992278, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6321052, Length=147, Percent_Identity=31.9727891156463, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37873; Mature: 37873

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLTFGRHTGLRVSEYALGTANFGTADTSAGRDTSRQIFDAFVAAGGTTFDTSNLYQDG
CCEEECCCCCCCEEHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
QAETVLGELLGSRRDDFVVITKYGGTRRDQPRPGTTGNSRKIMIRSLEASLRRLNTDYVD
CHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCEE
VFMPHFPDGTTPIDEILAGFDDLSRAGKIRYGGLSNFPAWRVAGAVVRADLRGLAPLVGI
EECCCCCCCCCCHHHHHHCHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHCHHHHCC
QTEYSLAERSAERELLPMVQAHGLGVFLYSPLAGGLLSGKYRQGGKGRLSVRGDAVERTV
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHCHHHCCCCCCCCCCEEEECCHHHHHHH
QQSAVVDGVLAVADEIGSTAVQVSLAWLRRRAVSARTALIPIVGPRTLSHLEQYLRSLEL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHCC
ELDEQHCRRLDEISAIRLGTPHEDVAAALAHGFDGDRTLLQTLYLPVI
CCCHHHHHHHHHHCEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRYLTFGRHTGLRVSEYALGTANFGTADTSAGRDTSRQIFDAFVAAGGTTFDTSNLYQDG
CCEEECCCCCCCEEHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
QAETVLGELLGSRRDDFVVITKYGGTRRDQPRPGTTGNSRKIMIRSLEASLRRLNTDYVD
CHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCEE
VFMPHFPDGTTPIDEILAGFDDLSRAGKIRYGGLSNFPAWRVAGAVVRADLRGLAPLVGI
EECCCCCCCCCCHHHHHHCHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHCHHHHCC
QTEYSLAERSAERELLPMVQAHGLGVFLYSPLAGGLLSGKYRQGGKGRLSVRGDAVERTV
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHCHHHCCCCCCCCCCEEEECCHHHHHHH
QQSAVVDGVLAVADEIGSTAVQVSLAWLRRRAVSARTALIPIVGPRTLSHLEQYLRSLEL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHCC
ELDEQHCRRLDEISAIRLGTPHEDVAAALAHGFDGDRTLLQTLYLPVI
CCCHHHHHHHHHHCEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]