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The map label for this gene is fdhA [H]

Identifier: 158312445

GI number: 158312445

Start: 680387

End: 682402

Strand: Direct

Name: fdhA [H]

Synonym: Franean1_0588

Alternate gene names: 158312445

Gene position: 680387-682402 (Clockwise)

Preceding gene: 158312444

Following gene: 158312448

Centisome position: 7.57

GC content: 68.85

Gene sequence:

>2016_bases
ATGACGGAGATATCGGTTACCGACACGAGGACGGTCCGCAGCTTCTGCCGGATCTGCACGTCCGTGTGCGGCATCCTCGT
CGAGACGGCTGGTGACAAGGTAGTTCGGGTACGGGGCGACCGTGACCACCCACTGTCGCGGGGATACACCTGTCCGAAGG
GCCGGTCACTCCCGCAGATGCACCATCATCCGGATCGCATCGAGCGTCCGCTGATGAAGGTCGACGGGGAGCTGCGGCCG
ACGACGTGGGAGGAGTGCCTGGACGATCTCGGCGCCCGGCTGCGAAACATCATCGAGCGGTACGGGCCCGAGTCGGTCGG
TGTCTTTTTCGGGAGCGGCATCGGCATGGACGCCGCCGGTTACCGGATGGCGCAGGCCCTGCACGCCGCGATCGGCACGC
CGGCGAAGTTCAGTCCCATGACCATCGACGGAACGGCCAAGGTGCTGACCGCGGATCTGGTGGGCGGTTCACCGGCTCTC
AGCGGCCGGCCCGACTACGACAACGCCTCGTTCGTCCTCTTCGTCGGCAGCAACCCGGTGGTGTCCCACGGGCACACCGT
CGCGATGCCGAACCCCACGGGCACCTTACGGGCGCTGCGGGAGCGGGCGGAGGTGTGGGTCATCGACCCCCGTCACACCG
AGACCGCCCGCCTGGCCGGCCACCATCTCGCGCCGCGTCCCGGCACCGACTACGCGGTCCTCGCCTACCTTGTCCGTGAG
ATCCTCCGCGACGGCGCCGACCGCGAGATGCTCTCCCGTCACACCCAGGGTGGCGAGATCCTGGCTGCCGCCGTTGAGCC
GTTCACTCTGGAGCACGCCGCCCGAATCGCCGATGTCTCCGCCGACGAGCTGGCCGCGCTCCTCGCCGGCGTGCGACGAG
CGGGGCGCGTCGCGATCGAAACCGGAACCGGCGTCACCATGGCGTCCAGCGCGAACGTCACGCAGTGGCTCGCCTGGTCA
CTAATGATTATCACTGGGTCGATGAACCAGCCCGGCGGCGCATGGTTCCACCCCGGCTTCAAAAACCAGCTGGAGGCCTT
CAAGCTGCCGATCTCGCCGCCCGAAGGCTCGTTCGGGCCGGGCCCGCGCAGCCGTCCGGAGACACAGTCCTTTCTCGGCG
AGTGGCCCTGTGCCGTTCTGGCCGACGAGATCCGCGCGGGCAACATCCGGGCGGTCCTCAATCTCGGCGGCCATCTCGTC
GCGGCCTTCCCCGACACCGAGACGCTGGTTCCCGCGCTGCGGGACCTGGAGCTGTTCGCCACCATCGAGATCATCGGCAA
CGAGACGACGGCCCTGTCCACCCACGTCCTGCCGACCAAGGACCAGCTGGAGCGGGCCGACGTGAGCCTGTGGGACTTCC
TGATACAGCGCGTCGCCGTCCAGCACACCCCTGCCGTCGTCGAACCGGTCGGGGACCGGCGTTCCGTGTGGTGGGTGCTC
GCGGAACTCGGACAGCGCCTCGGTTACCAGCTCGCCGACAGCAGATCCGGGCAGGTCACCGACGACACCCTGCTCGCCGA
GATCACCGCCCACGCCCGGCGCCCGTTCGGTGAGGTCGTCTCCGAAGGCTGGGTCGAGGTACCCCGCGAGATTCCCGCGC
CGTGGGTGGACGGGCACGTCGAGCGGATGGGGGGATGGCGCCTCGCTCCCCGGCTGCTCGTCGACCAGCTGGCCGCGCTC
CAGCCTCCCGCCCCGCTCGTCCTCACACCACGACGCCAGAAGCGCCATCTGAACTCCCAGTTCGACTACCTCGGAGAACA
GCCCGAGATCATCCTGCATCCCGACGACGCGGCAGCGGCCGGCGTGGTCGACAGTCAGCCGGTGACCGTCCGCTCGACCA
GCGGCGAGATCACCGGGATCGCGAAGGTCGACGGCACCATCCGCCGTGGAGCGGTCTCGATACCCCACGGCCACCAGTCG
GCGAACGTCAACCGGCTGACGGACAAGAGCCAGGTCGACATCGTCACCGGCATGGTCCGCTACTGCGGCATCCCGGTGAG
CGTCCACCCGGCATAG

Upstream 100 bases:

>100_bases
CCCGGGCCCGGGCCCGGGCCCGGGTCGGTCGGCCCGACCGGCCGATGTCGGCGATCGGTGGCTGAGCTGGTGAACCGGTG
CCAGAACCAGGAGGGTGACG

Downstream 100 bases:

>100_bases
GAGGTCCGTGCGCGGCCTCGCGCTCGGGTAATGGAATTCGGACAGCGGCCGCACGAGTCCGGCCGCTGTCCGCCATGGGC
GAGATGATCCCGCCGGGAGG

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MTEISVTDTRTVRSFCRICTSVCGILVETAGDKVVRVRGDRDHPLSRGYTCPKGRSLPQMHHHPDRIERPLMKVDGELRP
TTWEECLDDLGARLRNIIERYGPESVGVFFGSGIGMDAAGYRMAQALHAAIGTPAKFSPMTIDGTAKVLTADLVGGSPAL
SGRPDYDNASFVLFVGSNPVVSHGHTVAMPNPTGTLRALRERAEVWVIDPRHTETARLAGHHLAPRPGTDYAVLAYLVRE
ILRDGADREMLSRHTQGGEILAAAVEPFTLEHAARIADVSADELAALLAGVRRAGRVAIETGTGVTMASSANVTQWLAWS
LMIITGSMNQPGGAWFHPGFKNQLEAFKLPISPPEGSFGPGPRSRPETQSFLGEWPCAVLADEIRAGNIRAVLNLGGHLV
AAFPDTETLVPALRDLELFATIEIIGNETTALSTHVLPTKDQLERADVSLWDFLIQRVAVQHTPAVVEPVGDRRSVWWVL
AELGQRLGYQLADSRSGQVTDDTLLAEITAHARRPFGEVVSEGWVEVPREIPAPWVDGHVERMGGWRLAPRLLVDQLAAL
QPPAPLVLTPRRQKRHLNSQFDYLGEQPEIILHPDDAAAAGVVDSQPVTVRSTSGEITGIAKVDGTIRRGAVSIPHGHQS
ANVNRLTDKSQVDIVTGMVRYCGIPVSVHPA

Sequences:

>Translated_671_residues
MTEISVTDTRTVRSFCRICTSVCGILVETAGDKVVRVRGDRDHPLSRGYTCPKGRSLPQMHHHPDRIERPLMKVDGELRP
TTWEECLDDLGARLRNIIERYGPESVGVFFGSGIGMDAAGYRMAQALHAAIGTPAKFSPMTIDGTAKVLTADLVGGSPAL
SGRPDYDNASFVLFVGSNPVVSHGHTVAMPNPTGTLRALRERAEVWVIDPRHTETARLAGHHLAPRPGTDYAVLAYLVRE
ILRDGADREMLSRHTQGGEILAAAVEPFTLEHAARIADVSADELAALLAGVRRAGRVAIETGTGVTMASSANVTQWLAWS
LMIITGSMNQPGGAWFHPGFKNQLEAFKLPISPPEGSFGPGPRSRPETQSFLGEWPCAVLADEIRAGNIRAVLNLGGHLV
AAFPDTETLVPALRDLELFATIEIIGNETTALSTHVLPTKDQLERADVSLWDFLIQRVAVQHTPAVVEPVGDRRSVWWVL
AELGQRLGYQLADSRSGQVTDDTLLAEITAHARRPFGEVVSEGWVEVPREIPAPWVDGHVERMGGWRLAPRLLVDQLAAL
QPPAPLVLTPRRQKRHLNSQFDYLGEQPEIILHPDDAAAAGVVDSQPVTVRSTSGEITGIAKVDGTIRRGAVSIPHGHQS
ANVNRLTDKSQVDIVTGMVRYCGIPVSVHPA
>Mature_670_residues
TEISVTDTRTVRSFCRICTSVCGILVETAGDKVVRVRGDRDHPLSRGYTCPKGRSLPQMHHHPDRIERPLMKVDGELRPT
TWEECLDDLGARLRNIIERYGPESVGVFFGSGIGMDAAGYRMAQALHAAIGTPAKFSPMTIDGTAKVLTADLVGGSPALS
GRPDYDNASFVLFVGSNPVVSHGHTVAMPNPTGTLRALRERAEVWVIDPRHTETARLAGHHLAPRPGTDYAVLAYLVREI
LRDGADREMLSRHTQGGEILAAAVEPFTLEHAARIADVSADELAALLAGVRRAGRVAIETGTGVTMASSANVTQWLAWSL
MIITGSMNQPGGAWFHPGFKNQLEAFKLPISPPEGSFGPGPRSRPETQSFLGEWPCAVLADEIRAGNIRAVLNLGGHLVA
AFPDTETLVPALRDLELFATIEIIGNETTALSTHVLPTKDQLERADVSLWDFLIQRVAVQHTPAVVEPVGDRRSVWWVLA
ELGQRLGYQLADSRSGQVTDDTLLAEITAHARRPFGEVVSEGWVEVPREIPAPWVDGHVERMGGWRLAPRLLVDQLAALQ
PPAPLVLTPRRQKRHLNSQFDYLGEQPEIILHPDDAAAAGVVDSQPVTVRSTSGEITGIAKVDGTIRRGAVSIPHGHQSA
NVNRLTDKSQVDIVTGMVRYCGIPVSVHPA

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=713, Percent_Identity=24.2636746143057, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI1788534, Length=367, Percent_Identity=25.6130790190736, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI3868720, Length=279, Percent_Identity=28.3154121863799, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI171474008, Length=737, Percent_Identity=23.202170963365, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1787870, Length=542, Percent_Identity=23.0627306273063, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI3868719, Length=284, Percent_Identity=24.2957746478873, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081797, Length=743, Percent_Identity=21.399730820996, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 72737; Mature: 72605

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEISVTDTRTVRSFCRICTSVCGILVETAGDKVVRVRGDRDHPLSRGYTCPKGRSLPQM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHH
HHHPDRIERPLMKVDGELRPTTWEECLDDLGARLRNIIERYGPESVGVFFGSGIGMDAAG
CCCHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
YRMAQALHAAIGTPAKFSPMTIDGTAKVLTADLVGGSPALSGRPDYDNASFVLFVGSNPV
HHHHHHHHHHHCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCE
VSHGHTVAMPNPTGTLRALRERAEVWVIDPRHTETARLAGHHLAPRPGTDYAVLAYLVRE
EECCCEEECCCCCHHHHHHHHCCCEEEECCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHH
ILRDGADREMLSRHTQGGEILAAAVEPFTLEHAARIADVSADELAALLAGVRRAGRVAIE
HHHCCCCHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEE
TGTGVTMASSANVTQWLAWSLMIITGSMNQPGGAWFHPGFKNQLEAFKLPISPPEGSFGP
CCCCEEEECCCCHHHHHHEEEEEEECCCCCCCCCCCCCCHHHCHHHEECCCCCCCCCCCC
GPRSRPETQSFLGEWPCAVLADEIRAGNIRAVLNLGGHLVAAFPDTETLVPALRDLELFA
CCCCCCHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHHCCEEEE
TIEIIGNETTALSTHVLPTKDQLERADVSLWDFLIQRVAVQHTPAVVEPVGDRRSVWWVL
EEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHH
AELGQRLGYQLADSRSGQVTDDTLLAEITAHARRPFGEVVSEGWVEVPREIPAPWVDGHV
HHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHCCCCCCCCHH
ERMGGWRLAPRLLVDQLAALQPPAPLVLTPRRQKRHLNSQFDYLGEQPEIILHPDDAAAA
HHCCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCHHHHCCCCCCEEECCCCCCCC
GVVDSQPVTVRSTSGEITGIAKVDGTIRRGAVSIPHGHQSANVNRLTDKSQVDIVTGMVR
CCCCCCCEEEEECCCCEEEEEECCCCHHCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
YCGIPVSVHPA
HCCCCEEECCC
>Mature Secondary Structure 
TEISVTDTRTVRSFCRICTSVCGILVETAGDKVVRVRGDRDHPLSRGYTCPKGRSLPQM
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHH
HHHPDRIERPLMKVDGELRPTTWEECLDDLGARLRNIIERYGPESVGVFFGSGIGMDAAG
CCCHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
YRMAQALHAAIGTPAKFSPMTIDGTAKVLTADLVGGSPALSGRPDYDNASFVLFVGSNPV
HHHHHHHHHHHCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCE
VSHGHTVAMPNPTGTLRALRERAEVWVIDPRHTETARLAGHHLAPRPGTDYAVLAYLVRE
EECCCEEECCCCCHHHHHHHHCCCEEEECCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHH
ILRDGADREMLSRHTQGGEILAAAVEPFTLEHAARIADVSADELAALLAGVRRAGRVAIE
HHHCCCCHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEE
TGTGVTMASSANVTQWLAWSLMIITGSMNQPGGAWFHPGFKNQLEAFKLPISPPEGSFGP
CCCCEEEECCCCHHHHHHEEEEEEECCCCCCCCCCCCCCHHHCHHHEECCCCCCCCCCCC
GPRSRPETQSFLGEWPCAVLADEIRAGNIRAVLNLGGHLVAAFPDTETLVPALRDLELFA
CCCCCCHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHHCCEEEE
TIEIIGNETTALSTHVLPTKDQLERADVSLWDFLIQRVAVQHTPAVVEPVGDRRSVWWVL
EEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHH
AELGQRLGYQLADSRSGQVTDDTLLAEITAHARRPFGEVVSEGWVEVPREIPAPWVDGHV
HHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHCCCCCCCCHH
ERMGGWRLAPRLLVDQLAALQPPAPLVLTPRRQKRHLNSQFDYLGEQPEIILHPDDAAAA
HHCCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCHHHHCCCCCCEEECCCCCCCC
GVVDSQPVTVRSTSGEITGIAKVDGTIRRGAVSIPHGHQSANVNRLTDKSQVDIVTGMVR
CCCCCCCEEEEECCCCEEEEEECCCCHHCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
YCGIPVSVHPA
HCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3531194; 1378430 [H]