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The map label for this gene is uhpB [C]

Identifier: 158312390

GI number: 158312390

Start: 619891

End: 621204

Strand: Direct

Name: uhpB [C]

Synonym: Franean1_0532

Alternate gene names: 158312390

Gene position: 619891-621204 (Clockwise)

Preceding gene: 158312386

Following gene: 158312391

Centisome position: 6.9

GC content: 75.72

Gene sequence:

>1314_bases
ATGGCGTCACGGCCGCGAAGCCGGTCACGATGGGCTGTGTCCTCGGCCATGGTCGCTTCCGACGTCCTGTCCGTCCCGCC
CGGCCCGCTGCCCCGGGAGGGCGCCGCCTCGCCCGGAGCCCGTCCGGGCCATCCGCTGTGGCGCGCGCGCCCGTACCGGG
CCGACGTCTGGCTGGCGATCGGCCTGGCGGTCGCGACGATCACGGTGACACTGGTCTCGTCCGGTCGGGCGCCCTACCAC
CCGCCGGACGCGGTCACGGCGGCGCTGGCCGCGGTGTCCGCGCTGGCGCTGGCCTGGCGGCAGGCCGCGCCGCTCGCCGC
GATGGCGGTGACGTCGACGATCGTCGCGGTCAACGCCGCGGCCGGCTACGCCGTCGTGGCCGTCCAGTGGCCAGCGTGGC
TGGCTCTGTTCGGCTGCTTCTCGGTGGGCGGCCGTGGTGTCCGGATCGCCAGCACCGCGCTGTGCGTCATGGCCGTCGGC
GGCTACGCCCTCTTCGACCGCGGTGCCCTGACGGTCGAGGACATGGCCGGGATCACGATGTCCTTCCTCATCGCGACGGT
CGGCGGCGACGCCGCGCGCAGCCGCCGCGCGGTCGCCGCGGCGCAGCACGCCCAGGTTCGCGGCGAGGCACGGGAGCAGG
CGCTGGCCGCCGAGCGCCTGCTGCACGAGGAAAGAGGCCGGCTGGCGGGCGAGCTGCACGACGCGCTGGGCCACACCGTG
AACGTGATGGTGTTGCAGGCGGGCGTCGCGCGGCGGCTGTTCGCGGAGAACCCGGCCTTCGCCCAGCAGGCGCTCGCCGA
CATCGAGAACGTGGGCCGGGAAGCGCTGGGCGAGCTGGACCGGATGCTGCGGGTGCTGCATCCGGTCCAGGACCCGCGCC
AGGGCGACGGGGGCCTCGACGTGAGTGACGACGACCCGGACGACGCCCACGGCCAGGCGGGCGCCCAAGGACTGGCGGCG
CTCGCCGACCGGATCCGCGCCACCGGGCGGGAGGTGGACCTCGACGCCGAACCCGTCGACCTGTCGGCGGGCAGCGAGCG
GGTGCTGTACCGGATCGTGCGGGAGGCGCTGACCAACGCCGTCCGGCACACCGACACGGGACGGATCCGCGTTCGGGTCA
GCCGGGTCGCCGACCAGATCCGGGTCGAGGTGTTCAACGAGGGCGCCGGGTTCGCCTCCCCGGTGCCGGGCCGGGGGCTG
ATCGGCATGCGGGAGCGGGCCCGGCTCGAGGGCGGGTCGTTCGAGGCCGGACCCGTCGAGGGCGGCTTCCGGGTGCTGGC
CACCCTCCCGACGCACCCGGCCACCGGCTCGTGA

Upstream 100 bases:

>100_bases
GCGGGGGACCGGGGGTCGACACCCTGGCGGGTCGTATCGGCCCGCGTCTGGTCACCCTCGGCGTCACCCGCGCGGGTGAC
GCTGGCTGCCCGGCCTGGGG

Downstream 100 bases:

>100_bases
TCACCGTGCTGCTGGCCGACGACGACGGCCTGGTGCGCAGCGGGCTGCGGGCGTTGCTGGACGCCGAGCCGGACATCTGT
GTCGCCGCCGAGGCGGCCAC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MASRPRSRSRWAVSSAMVASDVLSVPPGPLPREGAASPGARPGHPLWRARPYRADVWLAIGLAVATITVTLVSSGRAPYH
PPDAVTAALAAVSALALAWRQAAPLAAMAVTSTIVAVNAAAGYAVVAVQWPAWLALFGCFSVGGRGVRIASTALCVMAVG
GYALFDRGALTVEDMAGITMSFLIATVGGDAARSRRAVAAAQHAQVRGEAREQALAAERLLHEERGRLAGELHDALGHTV
NVMVLQAGVARRLFAENPAFAQQALADIENVGREALGELDRMLRVLHPVQDPRQGDGGLDVSDDDPDDAHGQAGAQGLAA
LADRIRATGREVDLDAEPVDLSAGSERVLYRIVREALTNAVRHTDTGRIRVRVSRVADQIRVEVFNEGAGFASPVPGRGL
IGMRERARLEGGSFEAGPVEGGFRVLATLPTHPATGS

Sequences:

>Translated_437_residues
MASRPRSRSRWAVSSAMVASDVLSVPPGPLPREGAASPGARPGHPLWRARPYRADVWLAIGLAVATITVTLVSSGRAPYH
PPDAVTAALAAVSALALAWRQAAPLAAMAVTSTIVAVNAAAGYAVVAVQWPAWLALFGCFSVGGRGVRIASTALCVMAVG
GYALFDRGALTVEDMAGITMSFLIATVGGDAARSRRAVAAAQHAQVRGEAREQALAAERLLHEERGRLAGELHDALGHTV
NVMVLQAGVARRLFAENPAFAQQALADIENVGREALGELDRMLRVLHPVQDPRQGDGGLDVSDDDPDDAHGQAGAQGLAA
LADRIRATGREVDLDAEPVDLSAGSERVLYRIVREALTNAVRHTDTGRIRVRVSRVADQIRVEVFNEGAGFASPVPGRGL
IGMRERARLEGGSFEAGPVEGGFRVLATLPTHPATGS
>Mature_436_residues
ASRPRSRSRWAVSSAMVASDVLSVPPGPLPREGAASPGARPGHPLWRARPYRADVWLAIGLAVATITVTLVSSGRAPYHP
PDAVTAALAAVSALALAWRQAAPLAAMAVTSTIVAVNAAAGYAVVAVQWPAWLALFGCFSVGGRGVRIASTALCVMAVGG
YALFDRGALTVEDMAGITMSFLIATVGGDAARSRRAVAAAQHAQVRGEAREQALAAERLLHEERGRLAGELHDALGHTVN
VMVLQAGVARRLFAENPAFAQQALADIENVGREALGELDRMLRVLHPVQDPRQGDGGLDVSDDDPDDAHGQAGAQGLAAL
ADRIRATGREVDLDAEPVDLSAGSERVLYRIVREALTNAVRHTDTGRIRVRVSRVADQIRVEVFNEGAGFASPVPGRGLI
GMRERARLEGGSFEAGPVEGGFRVLATLPTHPATGS

Specific function: Member Of The Two-Component Regulatory System Uhpb/Uhpa Involved In The Regulation Of The Uptake Of Hexose Phosphates. Uhpb Functions As A Membrane-Associated Protein Kinase That Phosphorylates Uhpa In Response To Environmental Signals. [C]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=230, Percent_Identity=30, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 45744; Mature: 45612

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRPRSRSRWAVSSAMVASDVLSVPPGPLPREGAASPGARPGHPLWRARPYRADVWLAI
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
GLAVATITVTLVSSGRAPYHPPDAVTAALAAVSALALAWRQAAPLAAMAVTSTIVAVNAA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECC
AGYAVVAVQWPAWLALFGCFSVGGRGVRIASTALCVMAVGGYALFDRGALTVEDMAGITM
CCEEEEEEEHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHH
SFLIATVGGDAARSRRAVAAAQHAQVRGEAREQALAAERLLHEERGRLAGELHDALGHTV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
NVMVLQAGVARRLFAENPAFAQQALADIENVGREALGELDRMLRVLHPVQDPRQGDGGLD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VSDDDPDDAHGQAGAQGLAALADRIRATGREVDLDAEPVDLSAGSERVLYRIVREALTNA
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VRHTDTGRIRVRVSRVADQIRVEVFNEGAGFASPVPGRGLIGMRERARLEGGSFEAGPVE
HHCCCCCEEEEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCC
GGFRVLATLPTHPATGS
CCEEEEEECCCCCCCCC
>Mature Secondary Structure 
ASRPRSRSRWAVSSAMVASDVLSVPPGPLPREGAASPGARPGHPLWRARPYRADVWLAI
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
GLAVATITVTLVSSGRAPYHPPDAVTAALAAVSALALAWRQAAPLAAMAVTSTIVAVNAA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECC
AGYAVVAVQWPAWLALFGCFSVGGRGVRIASTALCVMAVGGYALFDRGALTVEDMAGITM
CCEEEEEEEHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHH
SFLIATVGGDAARSRRAVAAAQHAQVRGEAREQALAAERLLHEERGRLAGELHDALGHTV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
NVMVLQAGVARRLFAENPAFAQQALADIENVGREALGELDRMLRVLHPVQDPRQGDGGLD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VSDDDPDDAHGQAGAQGLAALADRIRATGREVDLDAEPVDLSAGSERVLYRIVREALTNA
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VRHTDTGRIRVRVSRVADQIRVEVFNEGAGFASPVPGRGLIGMRERARLEGGSFEAGPVE
HHCCCCCEEEEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCC
GGFRVLATLPTHPATGS
CCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8661927 [H]