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The map label for this gene is atpB [H]

Identifier: 157964057

GI number: 157964057

Start: 5159138

End: 5159968

Strand: Reverse

Name: atpB [H]

Synonym: Spea_4246

Alternate gene names: 157964057

Gene position: 5159968-5159138 (Counterclockwise)

Preceding gene: 157964058

Following gene: 157964056

Centisome position: 99.72

GC content: 41.28

Gene sequence:

>831_bases
ATGGCGACAACTGGGGATGACACGTTAACCGTAACGGCTTCCGACTATATCCAGCATCACCTGACTAATGCGAAAATGTG
TTCCGCTGATGGCGGGATTGCTTTTAACTATGCATGTCAAGATGCTGGATTTTGGACTTGGCACATTGACTCACTTTTGT
TTTCAGTTGGTCTAGGGGTTCTATTTTTGTGGTTATTCTACAAAGTAGGACAGAAGGCAACAATTGGCGTTCCAGGCAAG
CTTCAATGTTTCGTTGAAATGTGCGTGGAAGGTGTAGATAAAATTGTAAAAGACTCATTTCATGGGAAAAATGCAGTTAT
CGCACCATTAGGTCTAACTATTTTCGTCTGGGTTTTCCTGATGAACTTAATGGACTTGATCCCTGTTGACTTTGTACCTG
AGGCCGCCAAACGATTCTTAGGCGTACCTTACCTAAAGATTGTACCAACAACTGACTTGAACGTTACTTTAGGCTTAGCT
TTAAGTGTGTTCGCGTTAATTGTTTTTTACAGTATCAAGGTTAAAGGTATTGGTGGGTTCACTAAAGAACTGACTATGCA
GCCTTTCAATCATTGGGCACTAATTCCAATTAACTTTGTATTGGAAACAGTGACCTTGGTTGCGAAGCCGATTTCATTAT
CGCTTCGTCTGTTTGGTAACCTGTATGCAGGTGAGTTGATCTTTATTCTGATAGCACTGATGCCTTGGTGGGCTCAGTTT
GCATTATCAGTGCCTTGGGCCATTTTCCATATTTTGGTAATTGTGCTACAGGCGTTTATCTTCATGATGCTTACGATTGT
ATATCTAAGCATGGCACATGAAGACCATTAA

Upstream 100 bases:

>100_bases
GAAATCGTCATTCATGCCGTTATTCGTCAGTTATCTACTCGTGTTAGTCGTACCGTGGACAGCCCCTTTATACTTCAAAC
AAAATTAAGTGAGATTAATC

Downstream 100 bases:

>100_bases
TTTATTAAAAATTAGATACTTATCGGAGATAAAATGGAAACTGTAATTAGCTTTACAGCAATAGCTGTTGCAATTATGAT
CGGCTTAGCAGCGCTAGGTA

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MATTGDDTLTVTASDYIQHHLTNAKMCSADGGIAFNYACQDAGFWTWHIDSLLFSVGLGVLFLWLFYKVGQKATIGVPGK
LQCFVEMCVEGVDKIVKDSFHGKNAVIAPLGLTIFVWVFLMNLMDLIPVDFVPEAAKRFLGVPYLKIVPTTDLNVTLGLA
LSVFALIVFYSIKVKGIGGFTKELTMQPFNHWALIPINFVLETVTLVAKPISLSLRLFGNLYAGELIFILIALMPWWAQF
ALSVPWAIFHILVIVLQAFIFMMLTIVYLSMAHEDH

Sequences:

>Translated_276_residues
MATTGDDTLTVTASDYIQHHLTNAKMCSADGGIAFNYACQDAGFWTWHIDSLLFSVGLGVLFLWLFYKVGQKATIGVPGK
LQCFVEMCVEGVDKIVKDSFHGKNAVIAPLGLTIFVWVFLMNLMDLIPVDFVPEAAKRFLGVPYLKIVPTTDLNVTLGLA
LSVFALIVFYSIKVKGIGGFTKELTMQPFNHWALIPINFVLETVTLVAKPISLSLRLFGNLYAGELIFILIALMPWWAQF
ALSVPWAIFHILVIVLQAFIFMMLTIVYLSMAHEDH
>Mature_275_residues
ATTGDDTLTVTASDYIQHHLTNAKMCSADGGIAFNYACQDAGFWTWHIDSLLFSVGLGVLFLWLFYKVGQKATIGVPGKL
QCFVEMCVEGVDKIVKDSFHGKNAVIAPLGLTIFVWVFLMNLMDLIPVDFVPEAAKRFLGVPYLKIVPTTDLNVTLGLAL
SVFALIVFYSIKVKGIGGFTKELTMQPFNHWALIPINFVLETVTLVAKPISLSLRLFGNLYAGELIFILIALMPWWAQFA
LSVPWAIFHILVIVLQAFIFMMLTIVYLSMAHEDH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=268, Percent_Identity=62.6865671641791, Blast_Score=321, Evalue=3e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 30713; Mature: 30582

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTGDDTLTVTASDYIQHHLTNAKMCSADGGIAFNYACQDAGFWTWHIDSLLFSVGLGV
CCCCCCCEEEEEHHHHHHHHHCCCCEECCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHH
LFLWLFYKVGQKATIGVPGKLQCFVEMCVEGVDKIVKDSFHGKNAVIAPLGLTIFVWVFL
HHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHH
MNLMDLIPVDFVPEAAKRFLGVPYLKIVPTTDLNVTLGLALSVFALIVFYSIKVKGIGGF
HHHHHHCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHEEECCCCC
TKELTMQPFNHWALIPINFVLETVTLVAKPISLSLRLFGNLYAGELIFILIALMPWWAQF
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSVPWAIFHILVIVLQAFIFMMLTIVYLSMAHEDH
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATTGDDTLTVTASDYIQHHLTNAKMCSADGGIAFNYACQDAGFWTWHIDSLLFSVGLGV
CCCCCCEEEEEHHHHHHHHHCCCCEECCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHH
LFLWLFYKVGQKATIGVPGKLQCFVEMCVEGVDKIVKDSFHGKNAVIAPLGLTIFVWVFL
HHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHH
MNLMDLIPVDFVPEAAKRFLGVPYLKIVPTTDLNVTLGLALSVFALIVFYSIKVKGIGGF
HHHHHHCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHEEECCCCC
TKELTMQPFNHWALIPINFVLETVTLVAKPISLSLRLFGNLYAGELIFILIALMPWWAQF
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSVPWAIFHILVIVLQAFIFMMLTIVYLSMAHEDH
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA