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The map label for this gene is ina [H]

Identifier: 157963960

GI number: 157963960

Start: 5038145

End: 5040961

Strand: Reverse

Name: ina [H]

Synonym: Spea_4149

Alternate gene names: 157963960

Gene position: 5040961-5038145 (Counterclockwise)

Preceding gene: 157963961

Following gene: 157963958

Centisome position: 97.42

GC content: 46.5

Gene sequence:

>2817_bases
ATGAATAAACTTCTTAGCACTAAATTGTTGGCAGCAGCTTTTGCCTCATTAATTTCATTCTCTCCTACCGCTCTAGCAGC
GCCTATGTTTGGTGGCACGACAGCCGATGCCAATATTATCAATAAGGAGCAGGTTCTTTATTGGTTAATTAAGCGTGGAG
AGCTTGCTGCTAGTGCAACGGATGCGGAAAAAGAGCAAGCGATTGCCGAATTTACCAAGAGAGCAAATGGTAACAAAAAG
CTACCGCTTATTCAGGCGCAGCAGCAAAGAAAGCGTTTAGATCAAGTTGAAAAGCGCTCTAAGTCGATGAGTTATTCCGA
TAGCCAGGTAGAAGGCTTTAAGAGCAAAACGGTCAAGGTGCTTACCGTTCTTATCGATTTTCCTGACCTGCCCCACGATG
ACAATGGCTTAACTAGCAGCGATACCCAAATGTTTTATAACGACTATTCCGTTGAACATTATCGCTCACTGCTATTTTCA
AATTCAGGTTATGAAGGCCCTCAAGGGCAAACCTTGATGACAGGGTATCAATACTATCTGGCTGAATCAGGCGGCAGTTT
CTTCTTTACTGGTGATGTTAAAGGCTGGTACCGCGCAGCAAGCAATGCGGCGTTTTATGGGGGCAATGATCCCGACGATA
ATGATAACGATATTGCGGTTTCTGACTTAGTCAAAGAGGCTGTTGCTGCAGCCGTTGCAGGTATGAGTGATGCAGAGTTA
GCCAGTTACGATATCGAAGATCCTTTTGACTCAAATAATAACGGCATAACCAATGAAGCCGATGGCATTATTGACCATGT
GATGATTTTCCACTCCAGCATAGGCGAAGAGGCGGGTGGGGGCATGTTGGGCGCCGATGCGATCTGGTCCCATCGCTCTT
TTGTCGATGGCGGTAGTTATCGCTTACCCGGGACTGCAATGAAGCTTTCCGGCTATACCATTCAGCCTATCGACGCCGCG
CTGGGCGTGTGTGTACATGAGTTTGGCCATGATTTAGGACTGCCCGATGAATATGACACCACATCGCTAGGTAAAGGCTC
GCCTGTAGGCTTCTGGTCAATTATGGCAGGCGGAAGTTGGGCGGGTGAGCTTGCAGGCTCCTTACCTACAGGTTTTAGTC
CTTATGCTCGCTCTTATCTGCAGAGTATCTACGGTGGAAACTGGGTCACAGAGCAGACAGTCGCATTAGATTCGATCACC
AGTTCAGGCTTAGACCTCAATCTCGCTGAAGCCATAAATCACGATAAGGTTAATCAGATATCGATTGCCGTGCCCGCTGT
TGATATTGATTTTAAGGAGCCCTATAGCGGCAAGTATCAGTATTACTCTGCTCAAGGCCATATGATAAATCATGCCATGT
CATTTGATATCGATCTACCTGCAGTGTCGCCGCTTACGTTAACCATGCAGGCACACTGGAGCATTGAGGAAGATTATGAT
TATGCTCAGGTGATGGTCGATGGTGTTGCGATAGCAGGGCTTTACACTAAAGCGAGTAACTTGCGTAATCACGAACGCAA
CATTATTACCGGTAAGTCTAGTGATTTGGCTGCAGCTGAAGGTACCGATGCTTGGGTTAATCTTTCCTATGATTTAAGCC
CATATGCAGGAAGAGAGGTACGGCTTTCTATTCGTTACGTGACCGATCCAGCTGTGGGGGACTATGGCATAGTGATTGAT
GACATTAATATCAAACACGATGATACCGAAACGGTGTTCTCTAATGGCGCCGAGCTGGATGAAGATATTGCCTATGCGGG
ATTTATTCGGGTGGGCAATACGCGTCCGGGTAAAGACAGGCGTTACATTGTCCAGCTAAGAAGCCAACAAGGGATTGATA
AAGGGCTTAAATCTGAATCTTATGATCCTGGAGTCGTACTCTGGTTTGAAAACCAAGAGTACAGCGATAATGAAGTCAGT
AATCATCCAGGTTATAGCTTAATTAGTGTGGTCGATGCCGACCAGAATCTAATTGGCAGCAATGACTCTAGTGTACAGGT
GAGAGATGCCGCTTTCAGTCTATTTAACCAGTCGAGCTATTTTAACGATGATCACTTAAGTGGCGCCAAGCTATTCGATG
ATGCCAATGATTATAGTGCGCCGCTACAACCAGAATCAGGAACGGTATTACCAGAGCTTGGACTCACTATGGAGGTGATG
GCTCAATCGAGTAATAGCAGCAATGCTACAGTGCAGCTTAGGTATACCAGTCAAACGCCGCCCGATTCACAAGAGCTGAA
TACAAGCATTAGTTATAGCTTACAAGGTCGAGAGGCTAGCTTCTCCGCCAATGCCAGCGGTGGTGATGGTCATTATACTT
ACACTTGGGATTTTGGTATCACAGGTGCGACTAGCACAGAGGCATCTCCTCGCTATACATATGCGACAGATGGTAATTAC
TTAGTATCGCTAACTGTGACTGACGGTAATGGGGCAAGCTTTATTAATCATCTCAATGTTGTAGTGGGCTCTGCTATTGA
GGTCGATTTTACTCATAGTATCTCTAACTTGCAGGTGAGTTTTTCGGATCAATCTACAGGCGGCAATGGCGAGTTGAGCT
ATCAGTGGGAGTTTGGTGATGGTAATACTAGCTCGGCAGCTTCACCTAGCTATACCTATGGTACAGCTGGTAGCTATACC
GTGATGTTGACAGTGACAGACAGTATGGGGCAAACGGCGAAGAAGAGTGCCACCATAACGGTAACCGCGGCTGCAGTTGT
CGATAATGGTGGTGAATCATCGGGTGGAGGGAGTTTAGGTTGGCTTTCTGTATTGGTGCTTGGCTTGTTGAGTGCGCACC
GACGCCAACAATCATAA

Upstream 100 bases:

>100_bases
ACCGAACAGATGACTGAAATTGAAGCGGAAGCGGTGGTTATCGAATACATCCGCAAGCGTCAGCAGGCATTCCAAGATTG
TAAAAAAGGAAGTCAGTAGC

Downstream 100 bases:

>100_bases
ATACAAAAAGCCCAATTCACGGGCTTTTTTTAGCTGTTACATAACAGCCAATGTTTATAGCTTGGCAATGGCTTGCTGAG
CGGCGGGCAGAAATACTTCG

Product: peptidase M6 immune inhibitor A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 938; Mature: 938

Protein sequence:

>938_residues
MNKLLSTKLLAAAFASLISFSPTALAAPMFGGTTADANIINKEQVLYWLIKRGELAASATDAEKEQAIAEFTKRANGNKK
LPLIQAQQQRKRLDQVEKRSKSMSYSDSQVEGFKSKTVKVLTVLIDFPDLPHDDNGLTSSDTQMFYNDYSVEHYRSLLFS
NSGYEGPQGQTLMTGYQYYLAESGGSFFFTGDVKGWYRAASNAAFYGGNDPDDNDNDIAVSDLVKEAVAAAVAGMSDAEL
ASYDIEDPFDSNNNGITNEADGIIDHVMIFHSSIGEEAGGGMLGADAIWSHRSFVDGGSYRLPGTAMKLSGYTIQPIDAA
LGVCVHEFGHDLGLPDEYDTTSLGKGSPVGFWSIMAGGSWAGELAGSLPTGFSPYARSYLQSIYGGNWVTEQTVALDSIT
SSGLDLNLAEAINHDKVNQISIAVPAVDIDFKEPYSGKYQYYSAQGHMINHAMSFDIDLPAVSPLTLTMQAHWSIEEDYD
YAQVMVDGVAIAGLYTKASNLRNHERNIITGKSSDLAAAEGTDAWVNLSYDLSPYAGREVRLSIRYVTDPAVGDYGIVID
DINIKHDDTETVFSNGAELDEDIAYAGFIRVGNTRPGKDRRYIVQLRSQQGIDKGLKSESYDPGVVLWFENQEYSDNEVS
NHPGYSLISVVDADQNLIGSNDSSVQVRDAAFSLFNQSSYFNDDHLSGAKLFDDANDYSAPLQPESGTVLPELGLTMEVM
AQSSNSSNATVQLRYTSQTPPDSQELNTSISYSLQGREASFSANASGGDGHYTYTWDFGITGATSTEASPRYTYATDGNY
LVSLTVTDGNGASFINHLNVVVGSAIEVDFTHSISNLQVSFSDQSTGGNGELSYQWEFGDGNTSSAASPSYTYGTAGSYT
VMLTVTDSMGQTAKKSATITVTAAAVVDNGGESSGGGSLGWLSVLVLGLLSAHRRQQS

Sequences:

>Translated_938_residues
MNKLLSTKLLAAAFASLISFSPTALAAPMFGGTTADANIINKEQVLYWLIKRGELAASATDAEKEQAIAEFTKRANGNKK
LPLIQAQQQRKRLDQVEKRSKSMSYSDSQVEGFKSKTVKVLTVLIDFPDLPHDDNGLTSSDTQMFYNDYSVEHYRSLLFS
NSGYEGPQGQTLMTGYQYYLAESGGSFFFTGDVKGWYRAASNAAFYGGNDPDDNDNDIAVSDLVKEAVAAAVAGMSDAEL
ASYDIEDPFDSNNNGITNEADGIIDHVMIFHSSIGEEAGGGMLGADAIWSHRSFVDGGSYRLPGTAMKLSGYTIQPIDAA
LGVCVHEFGHDLGLPDEYDTTSLGKGSPVGFWSIMAGGSWAGELAGSLPTGFSPYARSYLQSIYGGNWVTEQTVALDSIT
SSGLDLNLAEAINHDKVNQISIAVPAVDIDFKEPYSGKYQYYSAQGHMINHAMSFDIDLPAVSPLTLTMQAHWSIEEDYD
YAQVMVDGVAIAGLYTKASNLRNHERNIITGKSSDLAAAEGTDAWVNLSYDLSPYAGREVRLSIRYVTDPAVGDYGIVID
DINIKHDDTETVFSNGAELDEDIAYAGFIRVGNTRPGKDRRYIVQLRSQQGIDKGLKSESYDPGVVLWFENQEYSDNEVS
NHPGYSLISVVDADQNLIGSNDSSVQVRDAAFSLFNQSSYFNDDHLSGAKLFDDANDYSAPLQPESGTVLPELGLTMEVM
AQSSNSSNATVQLRYTSQTPPDSQELNTSISYSLQGREASFSANASGGDGHYTYTWDFGITGATSTEASPRYTYATDGNY
LVSLTVTDGNGASFINHLNVVVGSAIEVDFTHSISNLQVSFSDQSTGGNGELSYQWEFGDGNTSSAASPSYTYGTAGSYT
VMLTVTDSMGQTAKKSATITVTAAAVVDNGGESSGGGSLGWLSVLVLGLLSAHRRQQS
>Mature_938_residues
MNKLLSTKLLAAAFASLISFSPTALAAPMFGGTTADANIINKEQVLYWLIKRGELAASATDAEKEQAIAEFTKRANGNKK
LPLIQAQQQRKRLDQVEKRSKSMSYSDSQVEGFKSKTVKVLTVLIDFPDLPHDDNGLTSSDTQMFYNDYSVEHYRSLLFS
NSGYEGPQGQTLMTGYQYYLAESGGSFFFTGDVKGWYRAASNAAFYGGNDPDDNDNDIAVSDLVKEAVAAAVAGMSDAEL
ASYDIEDPFDSNNNGITNEADGIIDHVMIFHSSIGEEAGGGMLGADAIWSHRSFVDGGSYRLPGTAMKLSGYTIQPIDAA
LGVCVHEFGHDLGLPDEYDTTSLGKGSPVGFWSIMAGGSWAGELAGSLPTGFSPYARSYLQSIYGGNWVTEQTVALDSIT
SSGLDLNLAEAINHDKVNQISIAVPAVDIDFKEPYSGKYQYYSAQGHMINHAMSFDIDLPAVSPLTLTMQAHWSIEEDYD
YAQVMVDGVAIAGLYTKASNLRNHERNIITGKSSDLAAAEGTDAWVNLSYDLSPYAGREVRLSIRYVTDPAVGDYGIVID
DINIKHDDTETVFSNGAELDEDIAYAGFIRVGNTRPGKDRRYIVQLRSQQGIDKGLKSESYDPGVVLWFENQEYSDNEVS
NHPGYSLISVVDADQNLIGSNDSSVQVRDAAFSLFNQSSYFNDDHLSGAKLFDDANDYSAPLQPESGTVLPELGLTMEVM
AQSSNSSNATVQLRYTSQTPPDSQELNTSISYSLQGREASFSANASGGDGHYTYTWDFGITGATSTEASPRYTYATDGNY
LVSLTVTDGNGASFINHLNVVVGSAIEVDFTHSISNLQVSFSDQSTGGNGELSYQWEFGDGNTSSAASPSYTYGTAGSYT
VMLTVTDSMGQTAKKSATITVTAAAVVDNGGESSGGGSLGWLSVLVLGLLSAHRRQQS

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: COG4412

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 100925; Mature: 100925

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS50093 PKD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLLSTKLLAAAFASLISFSPTALAAPMFGGTTADANIINKEQVLYWLIKRGELAASAT
CCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCHHHEEEEEEECCCEEECCC
DAEKEQAIAEFTKRANGNKKLPLIQAQQQRKRLDQVEKRSKSMSYSDSQVEGFKSKTVKV
CHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEE
LTVLIDFPDLPHDDNGLTSSDTQMFYNDYSVEHYRSLLFSNSGYEGPQGQTLMTGYQYYL
EEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCEEEECEEEEE
AESGGSFFFTGDVKGWYRAASNAAFYGGNDPDDNDNDIAVSDLVKEAVAAAVAGMSDAEL
EECCCCEEEECCCCHHHHHCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCHH
ASYDIEDPFDSNNNGITNEADGIIDHVMIFHSSIGEEAGGGMLGADAIWSHRSFVDGGSY
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECHHHHHCCCCCCCCCCE
RLPGTAMKLSGYTIQPIDAALGVCVHEFGHDLGLPDEYDTTSLGKGSPVGFWSIMAGGSW
ECCCCEEEECCCEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCC
AGELAGSLPTGFSPYARSYLQSIYGGNWVTEQTVALDSITSSGLDLNLAEAINHDKVNQI
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCEEHHHHCCCCCCCEE
SIAVPAVDIDFKEPYSGKYQYYSAQGHMINHAMSFDIDLPAVSPLTLTMQAHWSIEEDYD
EEEEEEEEECCCCCCCCCEEEEECCCCEEEEEEEEEECCCCCCCEEEEEEEEECCCCCCC
YAQVMVDGVAIAGLYTKASNLRNHERNIITGKSSDLAAAEGTDAWVNLSYDLSPYAGREV
HHHHHHHCEEEEEHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCCCEE
RLSIRYVTDPAVGDYGIVIDDINIKHDDTETVFSNGAELDEDIAYAGFIRVGNTRPGKDR
EEEEEEEECCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCEEEEEEEECCCCCCCCC
RYIVQLRSQQGIDKGLKSESYDPGVVLWFENQEYSDNEVSNHPGYSLISVVDADQNLIGS
EEEEEEHHHCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCHHCCC
NDSSVQVRDAAFSLFNQSSYFNDDHLSGAKLFDDANDYSAPLQPESGTVLPELGLTMEVM
CCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
AQSSNSSNATVQLRYTSQTPPDSQELNTSISYSLQGREASFSANASGGDGHYTYTWDFGI
ECCCCCCCCEEEEEECCCCCCCHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCC
TGATSTEASPRYTYATDGNYLVSLTVTDGNGASFINHLNVVVGSAIEVDFTHSISNLQVS
CCCCCCCCCCCEEEEECCCEEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEECCCEEEEE
FSDQSTGGNGELSYQWEFGDGNTSSAASPSYTYGTAGSYTVMLTVTDSMGQTAKKSATIT
ECCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCEEEEEEEECCCCCCHHCCEEEE
VTAAAVVDNGGESSGGGSLGWLSVLVLGLLSAHRRQQS
EEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKLLSTKLLAAAFASLISFSPTALAAPMFGGTTADANIINKEQVLYWLIKRGELAASAT
CCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCHHHEEEEEEECCCEEECCC
DAEKEQAIAEFTKRANGNKKLPLIQAQQQRKRLDQVEKRSKSMSYSDSQVEGFKSKTVKV
CHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEE
LTVLIDFPDLPHDDNGLTSSDTQMFYNDYSVEHYRSLLFSNSGYEGPQGQTLMTGYQYYL
EEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCEEEECEEEEE
AESGGSFFFTGDVKGWYRAASNAAFYGGNDPDDNDNDIAVSDLVKEAVAAAVAGMSDAEL
EECCCCEEEECCCCHHHHHCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCHH
ASYDIEDPFDSNNNGITNEADGIIDHVMIFHSSIGEEAGGGMLGADAIWSHRSFVDGGSY
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECHHHHHCCCCCCCCCCE
RLPGTAMKLSGYTIQPIDAALGVCVHEFGHDLGLPDEYDTTSLGKGSPVGFWSIMAGGSW
ECCCCEEEECCCEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCC
AGELAGSLPTGFSPYARSYLQSIYGGNWVTEQTVALDSITSSGLDLNLAEAINHDKVNQI
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCEEHHHHCCCCCCCEE
SIAVPAVDIDFKEPYSGKYQYYSAQGHMINHAMSFDIDLPAVSPLTLTMQAHWSIEEDYD
EEEEEEEEECCCCCCCCCEEEEECCCCEEEEEEEEEECCCCCCCEEEEEEEEECCCCCCC
YAQVMVDGVAIAGLYTKASNLRNHERNIITGKSSDLAAAEGTDAWVNLSYDLSPYAGREV
HHHHHHHCEEEEEHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCCCEE
RLSIRYVTDPAVGDYGIVIDDINIKHDDTETVFSNGAELDEDIAYAGFIRVGNTRPGKDR
EEEEEEEECCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCEEEEEEEECCCCCCCCC
RYIVQLRSQQGIDKGLKSESYDPGVVLWFENQEYSDNEVSNHPGYSLISVVDADQNLIGS
EEEEEEHHHCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCHHCCC
NDSSVQVRDAAFSLFNQSSYFNDDHLSGAKLFDDANDYSAPLQPESGTVLPELGLTMEVM
CCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
AQSSNSSNATVQLRYTSQTPPDSQELNTSISYSLQGREASFSANASGGDGHYTYTWDFGI
ECCCCCCCCEEEEEECCCCCCCHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCC
TGATSTEASPRYTYATDGNYLVSLTVTDGNGASFINHLNVVVGSAIEVDFTHSISNLQVS
CCCCCCCCCCCEEEEECCCEEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEECCCEEEEE
FSDQSTGGNGELSYQWEFGDGNTSSAASPSYTYGTAGSYTVMLTVTDSMGQTAKKSATIT
ECCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCEEEEEEEECCCCCCHHCCEEEE
VTAAAVVDNGGESSGGGSLGWLSVLVLGLLSAHRRQQS
EEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]