Click here to switch to the map view.

The map label for this gene is moaA [H]

Identifier: 157963931

GI number: 157963931

Start: 5003438

End: 5004418

Strand: Reverse

Name: moaA [H]

Synonym: Spea_4120

Alternate gene names: 157963931

Gene position: 5004418-5003438 (Counterclockwise)

Preceding gene: 157963933

Following gene: 157963930

Centisome position: 96.71

GC content: 47.2

Gene sequence:

>981_bases
ATGTCCCAACTACAAGACAATTTTGGTCGACGGTTTCATTATTTGCGTATGTCAGTGACTGACGTATGTAACTTTAAGTG
CACGTATTGCCTCCCAGATGGCTACCGCCCAGACGGTAAGCCTAAATTCCTCGATCTCAATGAAATCGAGCATCTGGTTT
CGGCTTTTTCACAAGTAGGCACCCAAAAAATCCGTATTACCGGTGGTGAGCCTTCTTTGCGTAAAGATTTCACCGACATC
ATTCGCATCGTTAAAGACAACGATAAGATTAAAACCATTGCCACGACTACTAACGGTTACCGTTTAGCTAAGCATGCCCA
AGAGTGGTATGACGCAGGGCTTAGGCGCATCAACATCTCGGTCGATAGTTTAGACCCGAAAATGTTCTACCAGATCACCG
GTGAGAATAAGTTTGATGAGGTGATGCGTGGTGTCGATGCGGCGCTAGAGGCAGGTTTCGAGCGAGTTAAAATCAATGCT
GTTCTGCTTAAAGGCCTGAATGATAAAGACTTGCCACGTTTTTTACATTGGATTAAGAACACCCCGATTGACTTACGTTT
CATTGAGTTAATGGAAACGGGTCTAGGCCACGATTACTTTAAGGCTCATCATCTAGCGGGTAACGACATCAAGTTGCAGC
TAGAGCAGGCGGGTTGGCAATTCGATACCCCAGCGGCTGACGACGGCCCTGCGCAAAACTTCAGCCATCAAGACTATCAA
GGCCGCATCGGGCTCATCATGCCTTACGCGAAAAACTTCTGTGCCAGTTGTAACCGCTTGCGAGTATCAGCCAAAGGTAA
ACTGCATCTTTGTCTGTTTACCGAAAATGGTGTCGACTTGCGTGACTTGCTGCAAACTCCAGATCAACAAGCTGAATTAA
TTGAACGCTTGCATGGTCAGCTTGCACAGAAAAAAGAAACCCACTTCCTGCATGACGGCATCACAGGCGTCACGCAGCAC
CTCGCTTCTATCGGCGGCTAA

Upstream 100 bases:

>100_bases
TACCCTACGTCGAGACAGATAAGGGTTTTTAGCCGTGGCAATAACGCCACCGGGGTGAGAAAAGAAATGATCTCACCTCC
CCTTACTTGGAAAGGTGATC

Downstream 100 bases:

>100_bases
TTAAACTCTGATCTGACGCAACTAAGTTGCGTCAGAAGCTAGGTATAATTGTCGCTATGACTCAGTACGAAATGAATCGG
ACAAATAAGAGACCATAATG

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSQLQDNFGRRFHYLRMSVTDVCNFKCTYCLPDGYRPDGKPKFLDLNEIEHLVSAFSQVGTQKIRITGGEPSLRKDFTDI
IRIVKDNDKIKTIATTTNGYRLAKHAQEWYDAGLRRINISVDSLDPKMFYQITGENKFDEVMRGVDAALEAGFERVKINA
VLLKGLNDKDLPRFLHWIKNTPIDLRFIELMETGLGHDYFKAHHLAGNDIKLQLEQAGWQFDTPAADDGPAQNFSHQDYQ
GRIGLIMPYAKNFCASCNRLRVSAKGKLHLCLFTENGVDLRDLLQTPDQQAELIERLHGQLAQKKETHFLHDGITGVTQH
LASIGG

Sequences:

>Translated_326_residues
MSQLQDNFGRRFHYLRMSVTDVCNFKCTYCLPDGYRPDGKPKFLDLNEIEHLVSAFSQVGTQKIRITGGEPSLRKDFTDI
IRIVKDNDKIKTIATTTNGYRLAKHAQEWYDAGLRRINISVDSLDPKMFYQITGENKFDEVMRGVDAALEAGFERVKINA
VLLKGLNDKDLPRFLHWIKNTPIDLRFIELMETGLGHDYFKAHHLAGNDIKLQLEQAGWQFDTPAADDGPAQNFSHQDYQ
GRIGLIMPYAKNFCASCNRLRVSAKGKLHLCLFTENGVDLRDLLQTPDQQAELIERLHGQLAQKKETHFLHDGITGVTQH
LASIGG
>Mature_325_residues
SQLQDNFGRRFHYLRMSVTDVCNFKCTYCLPDGYRPDGKPKFLDLNEIEHLVSAFSQVGTQKIRITGGEPSLRKDFTDII
RIVKDNDKIKTIATTTNGYRLAKHAQEWYDAGLRRINISVDSLDPKMFYQITGENKFDEVMRGVDAALEAGFERVKINAV
LLKGLNDKDLPRFLHWIKNTPIDLRFIELMETGLGHDYFKAHHLAGNDIKLQLEQAGWQFDTPAADDGPAQNFSHQDYQG
RIGLIMPYAKNFCASCNRLRVSAKGKLHLCLFTENGVDLRDLLQTPDQQAELIERLHGQLAQKKETHFLHDGITGVTQHL
ASIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=306, Percent_Identity=36.6013071895425, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI22027536, Length=306, Percent_Identity=36.6013071895425, Blast_Score=204, Evalue=7e-53,
Organism=Escherichia coli, GI1786999, Length=327, Percent_Identity=58.1039755351682, Blast_Score=408, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI32566329, Length=326, Percent_Identity=34.6625766871166, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17561210, Length=326, Percent_Identity=34.9693251533742, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI32566331, Length=307, Percent_Identity=35.5048859934853, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI28574488, Length=322, Percent_Identity=34.1614906832298, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI28574490, Length=309, Percent_Identity=34.6278317152104, Blast_Score=191, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 37034; Mature: 36902

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLQDNFGRRFHYLRMSVTDVCNFKCTYCLPDGYRPDGKPKFLDLNEIEHLVSAFSQVG
CCCHHHHHHHEEEHEEEEHHHHHCCEEEEECCCCCCCCCCCCEECHHHHHHHHHHHHHCC
TQKIRITGGEPSLRKDFTDIIRIVKDNDKIKTIATTTNGYRLAKHAQEWYDAGLRRINIS
CEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEE
VDSLDPKMFYQITGENKFDEVMRGVDAALEAGFERVKINAVLLKGLNDKDLPRFLHWIKN
EECCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHEEEEEEEEECCCCCCHHHHHHHHHC
TPIDLRFIELMETGLGHDYFKAHHLAGNDIKLQLEQAGWQFDTPAADDGPAQNFSHQDYQ
CCCCHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
GRIGLIMPYAKNFCASCNRLRVSAKGKLHLCLFTENGVDLRDLLQTPDQQAELIERLHGQ
CCEEEEEHHHHHHHCCCCEEEEECCCEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHH
LAQKKETHFLHDGITGVTQHLASIGG
HHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SQLQDNFGRRFHYLRMSVTDVCNFKCTYCLPDGYRPDGKPKFLDLNEIEHLVSAFSQVG
CCHHHHHHHEEEHEEEEHHHHHCCEEEEECCCCCCCCCCCCEECHHHHHHHHHHHHHCC
TQKIRITGGEPSLRKDFTDIIRIVKDNDKIKTIATTTNGYRLAKHAQEWYDAGLRRINIS
CEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEEE
VDSLDPKMFYQITGENKFDEVMRGVDAALEAGFERVKINAVLLKGLNDKDLPRFLHWIKN
EECCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHEEEEEEEEECCCCCCHHHHHHHHHC
TPIDLRFIELMETGLGHDYFKAHHLAGNDIKLQLEQAGWQFDTPAADDGPAQNFSHQDYQ
CCCCHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
GRIGLIMPYAKNFCASCNRLRVSAKGKLHLCLFTENGVDLRDLLQTPDQQAELIERLHGQ
CCEEEEEHHHHHHHCCCCEEEEECCCEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHH
LAQKKETHFLHDGITGVTQHLASIGG
HHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA