BacMap

Definition	Shewanella pealeana ATCC 700345 chromosome, complete genome.
Accession	NC_009901
Length	5,174,581

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The map label for this gene is caiD [H]

Identifier: 157963845

GI number: 157963845

Start: 4898687

End: 4899472

Strand: Reverse

Name: caiD [H]

Synonym: Spea_4034

Alternate gene names: 157963845

Gene position: 4899472-4898687 (Counterclockwise)

Preceding gene: 157963846

Following gene: 157963844

Centisome position: 94.68

GC content: 49.87

Gene sequence:

>786_bases
ATGAGTGAATCATTACACGTTACCCGCAATGGCGCTATTTTAGAAATTACTCTTGATAGACCTAAAGCCAACGCGATTGA
CGCAAAAACAAGTTTTGAGATGGGTGAGGTCTTCCTAGCTTTCCGTGAAGATCCTGAACTGCGTGTGGCGATTATTACTG
GTGCCGGTGAGCGCTTCTTCTCTGCGGGGTGGGATCTTAAAGCCGCTGCAGAGGGTGAAGCACCTGATGCTGATTTCGGT
CCAGGCGGATTTGCGGGTTTAACAGAAATTTTTGACTTAGATAAGCCGGTTATCGCTGCGGTAAACGGTTATGCATTCGG
TGGTGGTTTCGAGTTGGCGTTAGCAGCCGATATGATTATCTGTTCTGAAAATGCCAGCTTTGCACTACCAGAAGCTAAGT
TAGGCATCGTGCCTGATAGCGGCGGAATGCTGCGTCTACCTAAGTTGCTACCACCTGCGATAGTCAATGAACTGATGATG
ACAGGCCGTGGTATGGGCGCCGAAGAAGCCCTACGTTGGGGCGTGGTGAATCGCGTGGTTGAGAGTGACAAGCTGATGGA
AAGTGCTCGTGAGCTGGCTCAGCAAATTGCTCAAGGCGCGCCATTAGCTATCGCAGCGATCAAAGAGATCTATCGTGAAA
CTAGCGAGCTATCGGTGGAAGAGGGTTATCGCCATATTCGTGCTGGTGGCTTGAAAAATTACCCATCGGTACTGCGTTCA
GAAGATGCATTAGAGGGCCCATTAGCCTTCTCTGAGAAGCGTGACCCAGTGTGGAAGGGTAGATAG

Upstream 100 bases:

>100_bases
CCTGTACCTGCAAAGTACAAAAAAAACTTCTTATGTGAAGTTAACTTAATTTAGCTTTTTAATAAAAGAGTCTGAAGTGG
CTCTATATTGGAGTATTAGC

Downstream 100 bases:

>100_bases
GTTTCAGTACTATCAATCGAAATAGAGCCTGATATTTCCCATGGGATATCGGGTTTTATTTTAAGTGTTCGTCGGTAATG
GAAGGATTCACCAATGGCGT

Product: carnitinyl-CoA dehydratase

Products: L-Carnitine.; L-carnitinyl-CoA [C]

Alternate protein names: Crotonobetainyl-CoA hydratase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSESLHVTRNGAILEITLDRPKANAIDAKTSFEMGEVFLAFREDPELRVAIITGAGERFFSAGWDLKAAAEGEAPDADFG
PGGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADMIICSENASFALPEAKLGIVPDSGGMLRLPKLLPPAIVNELMM
TGRGMGAEEALRWGVVNRVVESDKLMESARELAQQIAQGAPLAIAAIKEIYRETSELSVEEGYRHIRAGGLKNYPSVLRS
EDALEGPLAFSEKRDPVWKGR

Sequences:

>Translated_261_residues
MSESLHVTRNGAILEITLDRPKANAIDAKTSFEMGEVFLAFREDPELRVAIITGAGERFFSAGWDLKAAAEGEAPDADFG
PGGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADMIICSENASFALPEAKLGIVPDSGGMLRLPKLLPPAIVNELMM
TGRGMGAEEALRWGVVNRVVESDKLMESARELAQQIAQGAPLAIAAIKEIYRETSELSVEEGYRHIRAGGLKNYPSVLRS
EDALEGPLAFSEKRDPVWKGR
>Mature_260_residues
SESLHVTRNGAILEITLDRPKANAIDAKTSFEMGEVFLAFREDPELRVAIITGAGERFFSAGWDLKAAAEGEAPDADFGP
GGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADMIICSENASFALPEAKLGIVPDSGGMLRLPKLLPPAIVNELMMT
GRGMGAEEALRWGVVNRVVESDKLMESARELAQQIAQGAPLAIAAIKEIYRETSELSVEEGYRHIRAGGLKNYPSVLRSE
DALEGPLAFSEKRDPVWKGR

Specific function: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=254, Percent_Identity=33.4645669291339, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI70995211, Length=269, Percent_Identity=32.3420074349442, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI68989263, Length=188, Percent_Identity=35.1063829787234, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI31542718, Length=249, Percent_Identity=28.5140562248996, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI37594471, Length=229, Percent_Identity=27.9475982532751, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI37594469, Length=229, Percent_Identity=27.9475982532751, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI4502327, Length=257, Percent_Identity=31.1284046692607, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI150378541, Length=254, Percent_Identity=29.9212598425197, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI260274832, Length=226, Percent_Identity=28.7610619469027, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI45643119, Length=226, Percent_Identity=28.7610619469027, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI260275230, Length=226, Percent_Identity=28.7610619469027, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI20127408, Length=201, Percent_Identity=26.865671641791, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI157694516, Length=218, Percent_Identity=27.5229357798165, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI213417737, Length=218, Percent_Identity=27.5229357798165, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI157694520, Length=182, Percent_Identity=29.1208791208791, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4757966, Length=136, Percent_Identity=25.7352941176471, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI51538581, Length=136, Percent_Identity=25.7352941176471, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI261878539, Length=93, Percent_Identity=39.7849462365591, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI25453481, Length=136, Percent_Identity=25.7352941176471, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI51538573, Length=136, Percent_Identity=25.7352941176471, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI221136756, Length=135, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI221136753, Length=135, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI221307494, Length=136, Percent_Identity=26.4705882352941, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI221142681, Length=261, Percent_Identity=85.0574712643678, Blast_Score=460, Evalue=1e-131,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=37.8787878787879, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI87082183, Length=218, Percent_Identity=32.5688073394495, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788682, Length=190, Percent_Identity=36.3157894736842, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1787660, Length=268, Percent_Identity=32.089552238806, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790281, Length=258, Percent_Identity=29.4573643410853, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788597, Length=248, Percent_Identity=27.8225806451613, Blast_Score=87, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI25145438, Length=258, Percent_Identity=34.8837209302326, Blast_Score=142, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17554946, Length=247, Percent_Identity=34.412955465587, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17560910, Length=249, Percent_Identity=29.3172690763052, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17540714, Length=228, Percent_Identity=32.8947368421053, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17534483, Length=257, Percent_Identity=27.6264591439689, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17536985, Length=265, Percent_Identity=26.0377358490566, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17540306, Length=246, Percent_Identity=28.0487804878049, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17558304, Length=220, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17549921, Length=217, Percent_Identity=26.7281105990783, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25144276, Length=233, Percent_Identity=28.755364806867, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508953, Length=233, Percent_Identity=28.755364806867, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508951, Length=233, Percent_Identity=28.755364806867, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=219, Percent_Identity=26.9406392694064, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25144157, Length=198, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25144160, Length=198, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129971, Length=240, Percent_Identity=34.1666666666667, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24653477, Length=240, Percent_Identity=34.1666666666667, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24653139, Length=276, Percent_Identity=34.0579710144928, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI19920382, Length=230, Percent_Identity=30.8695652173913, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19922422, Length=265, Percent_Identity=26.7924528301887, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI21357171, Length=223, Percent_Identity=30.9417040358744, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24654903, Length=185, Percent_Identity=29.7297297297297, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24650670, Length=196, Percent_Identity=32.1428571428571, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19921000, Length=187, Percent_Identity=29.9465240641711, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583077, Length=187, Percent_Identity=29.9465240641711, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583079, Length=187, Percent_Identity=29.9465240641711, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571730, Length=173, Percent_Identity=29.4797687861272, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571729, Length=173, Percent_Identity=29.4797687861272, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583165, Length=233, Percent_Identity=25.3218884120172, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022852
- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 28023; Mature: 27892

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESLHVTRNGAILEITLDRPKANAIDAKTSFEMGEVFLAFREDPELRVAIITGAGERFF
CCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCHHHEEEEECCCCCEEEEEEECCCCHHH
SAGWDLKAAAEGEAPDADFGPGGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADMII
HCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCEEECCCEEEEEEEEEEE
CSENASFALPEAKLGIVPDSGGMLRLPKLLPPAIVNELMMTGRGMGAEEALRWGVVNRVV
ECCCCCEECCCCCEEEEECCCCEEECCHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ESDKLMESARELAQQIAQGAPLAIAAIKEIYRETSELSVEEGYRHIRAGGLKNYPSVLRS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCC
EDALEGPLAFSEKRDPVWKGR
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SESLHVTRNGAILEITLDRPKANAIDAKTSFEMGEVFLAFREDPELRVAIITGAGERFF
CCCEEEECCCEEEEEEECCCCCCCCCCCCCCCHHHEEEEECCCCCEEEEEEECCCCHHH
SAGWDLKAAAEGEAPDADFGPGGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADMII
HCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCEEECCCEEEEEEEEEEE
CSENASFALPEAKLGIVPDSGGMLRLPKLLPPAIVNELMMTGRGMGAEEALRWGVVNRVV
ECCCCCEECCCCCEEEEECCCCEEECCHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ESDKLMESARELAQQIAQGAPLAIAAIKEIYRETSELSVEEGYRHIRAGGLKNYPSVLRS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCC
EDALEGPLAFSEKRDPVWKGR
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-Carnitine; D-carnitinyl-CoA [C]

Specific reaction: D-Carnitine = L-Carnitine. D-carnitinyl-CoA = L-carnitinyl-CoA [C]

General reaction: Isomerases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA